Ebglyss

Search documents
Lilly Down More Than 15% in a Year: Time to Buy, Sell or Hold?
ZACKS· 2025-07-10 15:11
Core Viewpoint - Eli Lilly and Company's stock has declined 15.7% over the past year due to a first-quarter earnings miss, guidance cut, and positive developments at rival Novo Nordisk, alongside broader economic challenges [1][10]. Group 1: Company Performance - Lilly's cardiometabolic division is its strongest segment, driven by the success of GLP-1 therapies Mounjaro and Zepbound, which together account for approximately 48% of total revenues [3][4]. - Despite slower-than-expected sales in the second half of 2024, Mounjaro and Zepbound saw a resurgence in the first quarter of 2025 due to new international market launches and improved supply [5][6]. - Lilly anticipates continued growth for Mounjaro and Zepbound through expanded international uptake and deeper market penetration in the U.S. [6][7]. Group 2: Product Pipeline and Future Growth - Lilly has secured approvals for several new therapies, including Omvoh, Jaypirca, Ebglyss, and Kisunla, which are expected to contribute to revenue growth in 2025 [10][11]. - The company is also advancing its pipeline in obesity, diabetes, and cancer, with several key mid and late-stage data readouts expected this year [12]. - Lilly is diversifying beyond GLP-1 drugs by expanding into cardiovascular, oncology, and neuroscience areas, including recent M&A deals to enhance its pipeline [13]. Group 3: Competitive Landscape - The obesity market is projected to reach $100 billion by 2030, with Lilly and Novo Nordisk currently dominating the space [14]. - Mounjaro and Zepbound face competition from Novo Nordisk's semaglutide products and emerging candidates from companies like Amgen and Viking Therapeutics [15][17]. - Other pharmaceutical companies are also entering the obesity market, which could challenge Lilly's and Novo Nordisk's market positions [18]. Group 4: Financial Outlook - Lilly expects 2025 revenues to be between $58 billion and $61 billion, indicating a year-over-year growth of approximately 32% [30]. - The company's stock has increased by over 400% in the past five years, primarily due to successful drug launches and a strong pipeline [29]. - Despite a high valuation with a price/earnings ratio of 29.54 compared to the industry average of 15.04, Lilly's stock is trading below its five-year mean [23].
Zepbound Powers Eli Lilly's Upbeat Q2 Outlook
Benzinga· 2025-07-09 18:55
Core Insights - Eli Lilly and Co. is expected to report adjusted earnings of $5.56 per share and sales of $14.4 billion for the second quarter [1] - The strong performance of the obesity drug Zepbound is driving higher expectations for the quarter [2] - Bank of America Securities has made minor adjustments to its earnings model, reflecting a slight increase in revenue and EPS forecasts due to anticipated stronger sales of Zepbound [3][4] Financial Projections - BofA expects total revenue to rise by 1% in 2025, with EPS growing by 1.9% in the same year, but a slight dip of 0.7% in 2026 [4] - Long-term forecasts for key products such as Mounjaro, Zepbound, orforglipron, and retatrutide remain largely unchanged [5] Analyst Ratings - BofA maintains a Buy rating on Eli Lilly with a price forecast of $1,000, citing the company's sustainable growth potential compared to peers [6] Earnings Call Focus Areas - The earnings call will address U.S. drug pricing changes and upcoming clinical trial results, including tirzepatide's SURPASS-CVOT and orforglipron's ATTAIN-1 [7] - Performance updates on major products like Mounjaro and Zepbound will be closely monitored, along with the launch progress of new drugs such as Kisunla and Ebglyss [8]
3 Reasons to Buy Eli Lilly Stock Like There's No Tomorrow
The Motley Fool· 2025-06-25 10:05
Core Viewpoint - Eli Lilly has shown exceptional financial performance and market growth, leading to a high forward price-to-earnings (P/E) ratio of over 35, which is significantly above the healthcare industry average of 15.8, raising questions about the timing of investment [1][2]. Group 1: Market Leadership in Weight Loss - Eli Lilly has established itself as a leader in the diabetes drug market and has made significant strides in the anti-obesity sector, with products like Mounjaro and Zepbound generating over $1 billion in quarterly revenue [4]. - The company is advancing its pipeline with investigational drugs such as orforglipron, an oral GLP-1 medicine, and retatrutide, a triple agonist, both showing promising clinical results [5]. - Eli Lilly has outperformed its competitor Novo Nordisk in the weight management market, capitalizing on clinical successes while the latter faced setbacks [6]. Group 2: Diversification of Product Line and Pipeline - Eli Lilly's portfolio includes successful drugs like Verzenio for cancer and Taltz for immunosuppression, along with potential future blockbusters such as Kisunla for Alzheimer's and Ebglyss for eczema [8]. - The company is actively expanding its pipeline through acquisitions, including SiteOne Therapeutics for $1 billion, which focuses on a non-opioid pain treatment, and Verve Therapeutics for $1.3 billion, which develops gene-editing therapies for cardiovascular diseases [9][10]. Group 3: Financial Outlook and Valuation Justification - Despite a high valuation that may deter some investors, Eli Lilly's revenue grew by 45% year over year to $12.7 billion, with net income increasing by 29% to $3 billion, showcasing strong financial health [12]. - The company's ongoing developments in weight management and diabetes are expected to yield significant clinical and regulatory successes, supporting above-average growth in the coming years, thus justifying its premium valuation [13].
Lilly Moves Past 50-Day Average: Should You Buy the Stock Now?
ZACKS· 2025-06-13 15:46
Core Insights - Eli Lilly and Company (LLY) has reached a significant support level, making it an attractive option for investors from a technical standpoint, with the stock breaking through its 50-day simple moving average (SMA), indicating a potential short-term bullish trend [1][9] - The company's cardiometabolic business, particularly the success of its diabetes drug Mounjaro and weight loss medicine Zepbound, has become a key driver of revenue [3][4] - Despite some challenges, Lilly expects substantial revenue growth in 2025, driven by Mounjaro, Zepbound, and other new drug approvals [31][32] Company Performance - LLY's stock has traded below its 50-day average since early May due to an earnings miss and guidance cut, but it has recently shown signs of recovery [2][9] - Mounjaro and Zepbound generated combined sales of $6.15 billion in Q1 2025, accounting for approximately 48% of the company's total revenues [4][9] - The company expects 2025 revenues to be between $58 billion and $61 billion, reflecting a 32% year-over-year growth [31][32] Product Pipeline and Growth Drivers - Lilly has launched Mounjaro in new international markets, including China, India, and Mexico, which is expected to drive future sales growth [6][11] - The FDA approved Zepbound for a second indication, which could further enhance sales [7] - Lilly's pipeline includes several promising candidates in obesity, diabetes, and cancer, with key mid and late-stage data readouts expected this year [11][12] Competitive Landscape - The obesity market is projected to expand to $100 billion by 2030, leading to increased competition, particularly from Novo Nordisk and other companies developing GLP-1-based therapies [14][15] - Mounjaro and Zepbound face competition from Novo Nordisk's semaglutide medicines and other emerging candidates from companies like Amgen and Viking Therapeutics [15][16] Financial Metrics and Valuation - Lilly's stock has risen 5.6% this year, outperforming the industry and S&P 500 [22][24] - The stock currently trades at a price/earnings ratio of 31.34, higher than the industry average of 15.51, but below its 5-year mean of 34.54 [26][29] - Estimates for Lilly's 2025 earnings have declined recently, but the company still shows solid growth prospects [29][32]
跨国药企CEO年薪晒一晒
Xin Lang Cai Jing· 2025-05-06 09:25
Core Insights - Johnson & Johnson remains the top revenue-generating pharmaceutical company with projected 2024 revenue of $88.8 billion, a 4% year-over-year increase [1][3] - The CEO compensation landscape has shifted, with Eli Lilly's CEO David Ricks now the highest-paid in the industry, earning $29.2 million in 2024, a 10% increase from 2023 [4][6] - The pharmaceutical industry is facing challenges from biosimilars, particularly affecting sales of established drugs like Humira and Stelara [2][1] Revenue Rankings - Johnson & Johnson leads with $88.8 billion in revenue, followed by AbbVie at $65.3 billion and Merck at $64.2 billion [3] - Other notable companies include Pfizer with $63.6 billion, and AstraZeneca with $54.1 billion, showing varying growth rates [3] CEO Compensation - Eli Lilly's David Ricks has surpassed Johnson & Johnson's Joaquin Duato, whose compensation decreased by approximately 14% to $24.6 million in 2024 [4][6] - Pfizer's CEO Albert Bourla earned $24.6 million, reflecting a 14% increase, while Merck's Robert Davis earned $23.2 million, also up by 14% [5][6] - Notably, Bristol Myers Squibb's CEO saw the highest percentage increase in compensation, rising by 122% [4][6] Market Dynamics - AbbVie's Humira faced a 37.6% decline in sales to $8.9 billion due to biosimilar competition, but its successors Skyrizi and Rinvoq are projected to generate over $17 billion in 2024 [2] - Merck's Keytruda and Gardasil are expected to account for approximately 59% of the company's total sales in 2024, highlighting the importance of these products [2]
LLY's Q1 Earnings Miss, Mounjaro & Zepbound Drive Sales, Stock Down
ZACKS· 2025-05-01 16:55
Core Viewpoint - Eli Lilly and Company reported mixed first-quarter 2025 results, missing earnings estimates but exceeding revenue expectations, driven by strong sales of its diabetes and weight loss medications [1][2][13]. Financial Performance - Adjusted EPS for Q1 2025 was $3.34, missing the Zacks Consensus Estimate of $3.52, but representing a 29% year-over-year increase [1]. - Total revenues reached $12.73 billion, a 45% increase year-over-year, surpassing the Zacks Consensus Estimate of $12.62 billion [2]. Key Drug Sales - Mounjaro sales were $3.84 billion, up 113% year-over-year, exceeding the Zacks Consensus Estimate of $3.75 billion [3]. - Zepbound generated $2.31 billion in sales, compared to $1.91 billion in the previous quarter, beating the Zacks Consensus Estimate of $2.27 billion [4]. - Trulicity sales fell 25% year-over-year to $1.1 billion, aligning with the Zacks Consensus Estimate [6]. - Jardiance sales increased 48% to $1.01 billion, significantly surpassing the Zacks Consensus Estimate of $675 million [7]. - Taltz generated $761.9 million, up 30% year-over-year, beating the Zacks Consensus Estimate of $663 million [7]. - Verzenio sales were $1.16 billion, a 10% increase year-over-year, but missed the Zacks Consensus Estimate of $1.25 billion [8]. - Emgality revenues dropped 45% to $124.6 million, while Olumiant sales rose 5% to $228.7 million [9]. Guidance and Market Position - The company maintained its 2025 revenue guidance of $58.0 billion to $61.0 billion, indicating a 32% year-over-year growth, but lowered EPS guidance to $20.78 to $22.28 [11][12]. - Competition from Novo Nordisk's semaglutide products is significant, with expectations of strong revenue growth for Novo's offerings [5][16]. - Lilly is investing in obesity treatments and has new molecules in clinical development, including a promising oral GLP-1 agonist [16][18]. Market Reaction - Despite strong sales, Lilly's shares fell nearly 5% in pre-market trading due to the EPS miss and lowered earnings guidance [14]. - CVS Caremark's decision to exclude Zepbound from its preferred drug list may impact sales [14]. - Lilly's stock has increased 16.7% year-to-date, outperforming the industry average of 3.5% [14].
Lilly(LLY) - 2025 Q1 - Earnings Call Presentation
2025-05-01 11:22
Financial Performance - Total revenue reached $12.7 billion, a 45% increase compared to Q1 2024[11] - Key product revenue surged to $7.5 billion, representing a 119% growth rate[11] - Non-GAAP earnings per share (EPS) increased by 29% to $3.34[11] - The company reaffirms its 2025 revenue guidance of $58.0 billion to $61.0 billion[9] Market Leadership and Expansion - The company gained U.S. incretin analogs market leadership with a 53.3% market share in total prescriptions[9] - Mounjaro U.S. type 2 diabetes incretin analogs TRx share of market (SOM) reached 39% and NBRx SOM 46% at the end of Q1 2025[22] - Zepbound U.S. branded anti-obesity TRx SOM exceeded 60% and NBRx SOM 74% at the end of Q1 2025[22] Strategic Investments and Pipeline Development - The company announced plans to double U.S. manufacturing investments, committing a total of $50 billion since 2020[9] - Research & Development investment reached $2.7 billion, accounting for 8% growth[11] - The company disclosed positive Phase 3 trial results for oral GLP-1, orforglipron, demonstrating statistically significant efficacy and a safety profile consistent with injectable GLP-1 medicines[9] - Jaypirca achieved Q1 2025 sales of $92 million and secured regulatory approval in the EU for relapsed or refractory CLL patients previously treated with a BTK inhibitor[22]