Investors with a lot of money to spend have taken a bullish stance on Eli Lilly (NYSE:LLY).And retail traders should know.We noticed this today when the trades showed up on publicly available options history that we track here at Benzinga.Whether these are institutions or just wealthy individuals, we don't know. But when something this big happens with LLY, it often means somebody knows something is about to happen.So how do we know what these investors just did? Today, Benzinga's options scanner spotted 26 ...

Core Viewpoint - Eli Lilly and Company has issued a full-year revenue forecast that significantly exceeds analyst expectations, driven by strong demand for its weight-loss and diabetes treatments, resulting in an over 8% increase in shares during premarket trading [1] Group 1: Financial Performance - The company reported fourth-quarter revenue of $19.29 billion, marking a 43% year-over-year increase and surpassing Bloomberg consensus estimates of $18.01 billion [2] - Growth was primarily driven by strong volume increases in Zepbound and Mounjaro, which generated sales of $4.26 billion and $7.41 billion, respectively, both exceeding Wall Street forecasts [2] - U.S. volumes expanded by 50% during the quarter, contributing to a 43% increase in U.S. revenue, which reached $12.9 billion [2] Group 2: International Performance - Internationally, Mounjaro continued to support volume growth, partially offsetting pressures related to Jardiance, a diabetes drug developed in partnership with Boehringer Ingelheim [3] - International results were positively impacted by a one-time $300 million benefit tied to changes in the Jardiance collaboration during the quarter [3] Group 3: Future Guidance - The company has guided for full-year revenue between $80 billion and $83 billion, with earnings per share projected to be between $33.50 and $35.00 [4]

Eli Lilly (LLY) reported $19.29 billion in revenue for the quarter ended December 2025, representing a year-over-year increase of 42.6%. EPS of $7.54 for the same period compares to $5.32 a year ago.The reported revenue compares to the Zacks Consensus Estimate of $17.87 billion, representing a surprise of +7.95%. The company delivered an EPS surprise of +7.88%, with the consensus EPS estimate being $6.99.While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and ...

Core Insights - Eli Lilly and Company (LLY) reported strong fourth-quarter 2025 results, with adjusted earnings per share (EPS) of $7.54, exceeding the Zacks Consensus Estimate of $6.99, and a year-over-year earnings increase of 42% [1] - Revenues reached $19.3 billion, a 43% increase year over year, driven by the success of GLP-1 drugs Mounjaro and Zepbound, surpassing the Zacks Consensus Estimate of $17.87 billion [1] Revenue Drivers - Mounjaro generated sales of $7.41 billion, up 110% year over year, exceeding the Zacks Consensus Estimate of $6.65 billion [2] - Zepbound recorded sales of $4.26 billion, a 123% increase year over year, also beating the Zacks Consensus Estimate of $3.87 billion [3] Competitive Landscape - Mounjaro and Zepbound face competition from Novo Nordisk's semaglutide products, with Novo Nordisk reporting a decline in its Diabetes and Obesity Care segment sales due to competitive pressure from Lilly's offerings [4] - Despite competitive dynamics, Mounjaro and Zepbound are expected to maintain strong demand in 2026 [13] Other Drug Performance - Trulicity generated $1.04 billion in revenue, down 17% year over year, but still beating the Zacks Consensus Estimate of $1.0 billion [5] - Jardiance sales fell 36% to $768 million, missing the Zacks Consensus Estimate of $776 million [5] - Taltz brought in $1.05 billion, up 10% year over year, exceeding the Zacks Consensus Estimate of $955 million [6] - Verzenio generated $1.60 billion, up 3% year over year, but missed the Zacks Consensus Estimate of $1.62 billion [6] Full-Year Performance - For the full year 2025, Eli Lilly's sales rose 45% to $65.2 billion, significantly beating the Zacks Consensus Estimate of $63.54 billion [10] - Adjusted earnings for 2025 were $24.21 per share, an 86% increase year over year, surpassing the Zacks Consensus Estimate of $23.74 [10] 2026 Outlook - Eli Lilly expects 2026 revenues in the range of $80 billion to $83 billion, higher than the Zacks Consensus Estimate of $77.5 billion [11] - EPS for 2026 is projected to be between $33.50 and $35.00, exceeding the Zacks Consensus Estimate of $33.24 [11] Market Reaction - Following the positive quarterly earnings and optimistic 2026 outlook, Lilly's shares rose approximately 9% in pre-market trading [14] - Over the past year, Lilly's stock has increased by 19.2%, outperforming the industry average of 17.1% [14] Strategic Initiatives - Lilly is investing in obesity treatments and has several new molecules in clinical development, including orforglipron, an oral GLP-1 small molecule [16][17] - The company is diversifying its portfolio beyond GLP-1 drugs into cardiovascular, oncology, and neuroscience areas, including recent acquisitions to enhance its capabilities in oral small-molecule therapies [19]

Core Insights - Financial giants are showing a bullish sentiment towards Eli Lilly and Co, with 47% of traders being bullish and 29% bearish based on options trading analysis [1] - The predicted price range for Eli Lilly and Co is between $720.0 and $1580.0, indicating significant interest from major players [2] - The average open interest for options stands at 224.91, with a total volume of 1,733.00, reflecting active trading in the past month [3] Options Activity - The largest options trades include a bullish sweep call with a total trade value of $967.9K at a strike price of $1160.00, indicating strong bullish sentiment [6] - Other notable trades include bearish calls with varying strike prices, showcasing mixed sentiments among traders [6] Company Overview - Eli Lilly and Co specializes in neuroscience, cardiometabolic, cancer, and immunology, with key products including Verzenio, Mounjaro, and Taltz [7] - Analysts have set an average price target of $1205.5 for Eli Lilly and Co, reflecting positive expectations for the stock [8] Market Performance - The current trading volume for Eli Lilly is 709,068, with the stock price up by 0.99% to $1089.16, indicating a stable market position [10] - Analysts from Guggenheim maintain a Buy rating with a target price of $1161, while UBS has adjusted its target price to $1250, reflecting confidence in the company's future performance [10]

Company Overview - Eli Lilly and Co is a pharmaceutical company focusing on neuroscience, cardiometabolic diseases, cancer, and immunology. Key products include Verzenio for cancer, Mounjaro, Zepbound, Jardiance, Trulicity, Humalog, and Humulin for cardiometabolic conditions, and Taltz and Olumiant for immunology [8]. Current Market Status - The current market price of Eli Lilly (LLY) is $1,069.3, reflecting a decrease of 0.73%. The stock has a trading volume of 1,133,591. RSI indicators suggest that the stock may be approaching overbought conditions. The next earnings report is expected in 21 days [10]. - Market experts have issued ratings for Eli Lilly, with a consensus target price set at $1,250. An analyst from UBS has downgraded the stock to a Buy rating with the same price target [9]. Options Trading Insights - Recent options trading activity indicates a bearish sentiment among large investors, with 45% of trades being bearish and 35% bullish. A total of 120 uncommon options trades were detected, with 39 puts amounting to $1,794,386 and 81 calls totaling $4,052,883 [2][3]. - The significant investors are targeting a price range for Eli Lilly between $610.0 and $1,660.0 over the past three months [3]. - The mean open interest for Eli Lilly options trades is 387.99, with a total volume of 2,219.00 [4].

Company Overview - Eli Lilly and Company (LLY) has a market cap of $1 trillion and is a leading global research-based pharmaceutical company, founded in 1876 and headquartered in Indianapolis, Indiana. The company offers a wide range of prescription medicines, including treatments for type 2 diabetes, weight management, cancer, autoimmune conditions, and established insulin therapies [1] Earnings Expectations - Analysts anticipate Eli Lilly to report Q4 earnings of $7.47 per share, representing a 40.4% increase from $5.32 per share in the same quarter last year. The company has surpassed Wall Street's EPS estimates in three of the last four quarters [2] - For fiscal 2025, the expected EPS is $23.95, an 84.4% increase from $12.99 in fiscal 2024, with a projected rise to $33.59 in fiscal 2026, reflecting a 40.3% annual growth [3] Stock Performance - Eli Lilly's stock has increased by 35.1% over the past 52 weeks, outperforming the S&P 500 Index's 19.7% gains and the S&P 500 Healthcare Sector SPDR's 12.7% returns during the same period [4] Strategic Developments - On January 7, Eli Lilly's shares rose by 3.3% following the announcement of a strategic partnership with Nimbus Therapeutics to develop an oral obesity treatment, which includes a $55 million upfront payment and potential milestone payments of up to $1.3 billion. Additionally, the company is in advanced talks to acquire Ventyx Biosciences for over $1 billion, aimed at enhancing its drug portfolio and reinforcing its position in the weight-loss therapeutics market [5] Analyst Consensus - The consensus opinion on Eli Lilly stock is "Strong Buy," with 22 out of 27 analysts recommending a "Strong Buy," two suggesting a "Moderate Buy," and three advising a "Hold." The average analyst price target for Eli Lilly is $1,161.76, indicating a potential upside of 7.5% from current price levels [6]

Core Viewpoint - The article discusses the planned price increases of prescription drugs by U.S. pharmaceutical companies in 2026, despite ongoing pressure from the Trump administration to lower drug prices. The number of drugs set for price increases has risen compared to the previous year, indicating a persistent issue with high drug costs in the U.S. [5][7] Price Increases - U.S. pharmaceutical companies plan to raise prices on at least 350 prescription drugs in 2026, including vaccines for COVID-19, respiratory syncytial virus (RSV), and shingles, as well as the cancer drug Ibrance [5] - The median price increase for these drugs is approximately 4%, consistent with the increase seen in 2025 [5] - In contrast, around 9 drugs will see price reductions, with the diabetes drug Jardiance and its related medications experiencing a price drop of over 40% [5] Comparison with Other Countries - Patients in the U.S. pay significantly higher prescription drug costs compared to other developed countries, often nearly three times as much [7] - Despite agreements reached by Trump with 14 pharmaceutical companies to lower some drug prices, companies still plan to increase prices starting January 1 [7] Specific Company Actions - Pfizer plans to adjust prices for about 80 drugs, including Ibrance, Nurtec, and Paxlovid, with most increases below 10%. However, the price of the COVID-19 vaccine Comirnaty will rise by 15%, and some hospital drugs will see increases exceeding four times their previous prices [7] - European pharmaceutical company GSK intends to raise prices on approximately 20 drugs and vaccines, with increases ranging from 2% to 8.9% [8] Legislative and Market Context - U.S. pharmaceutical companies have been reducing significant price hikes in recent years due to legislative scrutiny and government policies that penalize drug prices exceeding inflation rates [8] - More price adjustments are expected to be announced in early January, a traditional peak period for pharmaceutical price changes [8]

Company Overview - Eli Lilly is a pharmaceutical company focusing on neuroscience, cardiometabolic diseases, cancer, and immunology, with key products including Verzenio, Mounjaro, Zepbound, Jardiance, Trulicity, Humalog, Humulin, Taltz, and Olumiant [11]. Market Sentiment - Recent options trading indicates a bearish sentiment among large investors, with 42% bearish and 39% bullish positions noted [3]. - A total of 33 uncommon options trades were identified, with 9 puts amounting to $1,005,471 and 24 calls totaling $1,892,620 [2][3]. Options Analysis - The average open interest for Eli Lilly options is 420.12, with a total volume of 954.00, indicating significant trading activity [5]. - The price target for Eli Lilly based on recent options activity is projected between $500.0 and $1600.0 [4]. Expert Ratings - Analysts have provided an average target price of $1,222.67 for Eli Lilly, with individual ratings from Wells Fargo, BMO Capital, and B of A Securities maintaining target prices of $1,200 and $1,268 [12][13]. Current Stock Performance - Eli Lilly's stock price is currently at $1,064.19, reflecting a decrease of 0.98%, with upcoming earnings expected in 34 days [15].

Core Insights - U.S. pharmaceutical companies plan to increase the prices of at least 350 brand-name drugs in 2026, despite pressure from the Trump administration to lower prices [1] - The scale of price increases has expanded from over 250 drugs in the previous year, with a median increase of approximately 4%, consistent with 2025 [1] - Major drugs affected include vaccines for COVID-19, respiratory syncytial virus, shingles, and the cancer drug Ibrance [1] Group 1: Price Increases - Pfizer leads with the highest number of price increases, planning to raise prices on about 80 different drugs, including Ibrance, Nurtec, and Paxlovid [2] - Most of Pfizer's price increases are below 10%, but the COVID-19 vaccine Comirnaty will see a 15% increase, while some hospital medications will increase by over four times [2] - GlaxoSmithKline plans to raise prices on approximately 20 drugs and vaccines by 2% to 8.9%, emphasizing that price increases are necessary to support scientific innovation [2] Group 2: Price Decreases - A small number of drugs will see price reductions, including Boehringer Ingelheim's diabetes drug Jardiance, which will decrease by over 40% [3] - Jardiance is one of the ten drugs targeted for price negotiations under the U.S. government's Medicare plan for individuals aged 65 and older, with a two-thirds price cut agreed upon by Boehringer Ingelheim and Eli Lilly [3] Group 3: Government Agreements and Trends - Despite agreements with 14 pharmaceutical companies regarding some drug prices under government programs, the trend of price increases continues [4] - Companies like Pfizer, Sanofi, Boehringer Ingelheim, Novartis, and GlaxoSmithKline still plan to raise prices on certain drugs, indicating a strategy to maximize list prices while negotiating discounts behind the scenes [4] - Historical data shows that January is typically the month with the highest number of price adjustments, suggesting more increases and decreases are expected in early January [3][4]