Core Viewpoint - PerkinElmer announced a price adjustment for consumables effective January 1, 2026, due to rising procurement costs influenced by tariffs and other factors [5][6]. Group 1: Price Adjustment Announcement - The company expressed gratitude to its customers and partners for their ongoing support [5]. - The price adjustment is a response to the continuous increase in procurement costs, particularly core procurement costs [5][6]. - The company has attempted to mitigate these pressures through operational optimizations and cost reductions but found it insufficient to fully offset the rising costs [5][6]. Group 2: Implementation Details - The price adjustment will vary across different products, and specific pricing details will be available through the official WeChat account or by consulting regional sales personnel [6]. - The company aims to ensure stable and high-quality product supply and service assurance despite the cost increases [6].

摘要 ： 近日，齐鲁工业大学发布多批政府采购意向，仪器信息网特对其中的仪器设备品目进行梳理，统 计出29项仪器设备采购意向，预算总额达1.68亿元。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我 们的推送。 近日， 齐鲁工业大学发布 29 项仪器设备采购意向，预算总额达 1.68亿 元，涉及 场发射透 射电子显微镜,耐破度仪,透气度测试仪,纤维分析仪,压缩强度测试仪,撕裂度仪,打浆度测定仪,肖 伯尔耐折度仪,自动纸浆粘度计,超声波桌面型喷涂机,热重分析仪,动态热机械分析仪,红外水蒸 气透过率测试仪,压差法气体透过率测定仪,原位傅立叶变换红外光谱仪,荧光光谱仪,纳米粒度与 ZETA测定仪,全自动比表面积孔径分析仪,倒置荧光显微镜,正置专业偏光荧光显微系统,微射流 高压纳米均质机,堆肥红外法生物降解仪,白度仪,耐破度仪,平滑度仪,耐折度仪,内结合强度仪,高 效液相色谱仪,气相色谱质谱联用仪等，预计采购时间为2 0 2 5 年 4~12 月。 部分采购仪器简介： 肖伯尔耐折度仪 肖伯尔耐折度仪是一种标准化测试设备，用于评估材料在反复折叠下的耐久性，通过夹 ...

Core Insights - Guangxi Medical University has announced six procurement intentions for laboratory instruments, with a total budget of 111 million yuan [2][3]. Procurement Overview - The procurement includes advanced instruments such as: - Coherent Raman Spectroscopy - Fully Automated Integrated Droplet Digital PCR - X-ray Powder Diffraction Instrument - Chemiluminescence Imaging System - Inductively Coupled Plasma Mass Spectrometry System - Rotational Shear Rheometer - Protein Liquid Chromatography System - The expected procurement date is December 2025 [3]. Instrument Descriptions - **Fully Automated Integrated Droplet Digital PCR**: This technology offers high sensitivity and absolute quantification of nucleic acids, crucial for applications in oncology, pathogen detection, and prenatal testing [4]. - **X-ray Powder Diffraction Instrument**: A fundamental tool for material characterization, it accurately determines crystal structures and compositions, essential for various fields including materials science and pharmaceuticals [5][6]. - **Rotational Shear Rheometer**: This instrument measures the flow characteristics and viscoelastic behavior of materials, applicable in polymer science, food science, and chemical engineering [7]. Research and Development Strengths - Guangxi Medical University is recognized as a leading medical institution in the region, with a strong focus on research in nasopharyngeal and liver cancers, contributing significantly to public health [11][13]. - The university has established several national-level research platforms, enhancing its capabilities in translational medicine and clinical applications [11][12].

Core Insights - The article discusses the recent announcement by zycgr regarding 14 procurement intentions for scientific instruments, with a total budget of 396 million yuan [2][3]. Procurement Overview - The procurement includes various advanced instruments such as inductively coupled plasma etching machines, non-destructive global film thickness testing systems, multi-chamber deep silicon etching machines, and high-vacuum high-speed deposition systems [3][4]. - The expected procurement date is set for December 2025 [3]. Detailed Procurement List - The procurement list includes: - Dilution refrigerator: 700,000 yuan, requiring at least one year of warranty and lifetime technical support [5]. - Arbitrary waveform generator: 1.1 million yuan, with specifications including 4-channel output and a sampling rate of 10 GSa/s [5]. - High-vacuum high-speed deposition system: 2 million yuan, with a vacuum requirement of less than 5e-8 Torr [5]. - Inductively coupled plasma etching machine: 46.16 million yuan, for etching ion traps and quantum materials [5]. - Non-destructive global film thickness testing system: 1.5 million yuan, for testing film thickness distribution on 12-inch wafers [6]. - Multi-chamber deep silicon etching machine: 18 million yuan, for advanced packaging TSV hole etching [6]. - Fully automatic uniform coating and developing system: 32 million yuan, for automated coating and developing processes [6]. - Automated robot wafer transfer and workflow monitoring system: 100 million yuan, aimed at improving process efficiency [6]. - Ultra-stable lasers and other specialized laser systems with various specifications and budgets ranging from 143,000 to 238,000 yuan [6]. Conclusion - The procurement intentions reflect a significant investment in advanced scientific instruments, indicating a focus on enhancing research capabilities and technological advancements in the relevant fields [2][3].

Core Viewpoint - The article discusses the introduction of LipidIN, a novel AI model for lipidomics that significantly enhances the speed and depth of lipid identification while enabling platform-independent analysis [1][3]. Group 1: Importance of Lipids - Lipids are crucial molecules in living organisms, serving as structural components of cell membranes, energy reserves, and signaling messengers [2]. - Lipidomics can reveal metabolic abnormalities linked to major diseases such as cardiovascular diseases, tumors, and diabetes, but the complexity of lipid molecules presents significant research challenges [2]. Group 2: Development of LipidIN - The research team from Xiamen University published their findings in Nature Communications, introducing LipidIN as the first rapid, platform-independent reverse lipidomics mass spectrometry AI model [3]. - LipidIN integrates the lipid categories intelligence (LCI) model and the wide-spectrum modeling yield network (WMYn) model for lipid mass spectrometry data analysis [4]. Group 3: Features of LipidIN - LipidIN employs a four-tier workflow: 1. Establishing a tiered spectral library covering 121 lipid classes with 168 million theoretical spectra 2. Implementing a rapid search module capable of over 100 billion spectral matches per second 3. Utilizing the LCI model to reduce false positive rates 4. Generating high-resolution secondary fingerprint spectra through WMYn [5][6]. Group 4: Performance Evaluation - The platform demonstrated stable performance across various biological samples and successfully adapted to different technical platforms, providing significant technical assurance for data comparability in the field [6]. - LipidIN achieved a false discovery rate of 5.7% and successfully annotated 8,923 lipid species across species, with a 20% improvement in target molecule recall rate [6]. Group 5: Comparative Analysis - In performance comparisons with existing tools like MS-DIAL, LipidSearch, and others, LipidIN showed a recall rate of over 90% when using its tiered spectral library strategy, significantly outperforming traditional methods [12]. - The LCI module of LipidIN outperformed the LDA method in annotation accuracy across most lipid subclasses, demonstrating its effectiveness in removing false positives [13]. Group 6: High-Resolution Spectrum Reconstruction - The WMYn model was systematically compared with various spectrum prediction methods, showing superior prediction accuracy, especially at high resolution [14]. - The integration of a five-tier spectral library into the Entropy Search framework further enhanced the recall rates for various lipid subclasses, validating LipidIN's unique value in complex lipid analysis [14].

Core Insights - The article emphasizes a significant shift in the scientific instrument industry from "selling equipment" to "selling services," highlighting the importance of after-sales service as a core element of brand trust [2][3] - The "Customer Care Season" initiative, launched in 2021, has seen participation from 30 brand partners and over 9,000 users, showcasing the proactive approach to after-sales service [2][3] Group 1: Customer Care Season Overview - The "Customer Care Season" has evolved over five years, with over 9000 users participating and more than 100 engineers providing live Q&A sessions [2][3] - In 2025, the initiative will upgrade to include live streaming and on-site inspections, enhancing user engagement and service visibility [3] Group 2: Brand Participation and Strategies - PerkinElmer has introduced a one-stop service system since 2010, enhancing user experience through live demonstrations in real lab settings [5][6] - Thermo Fisher has created five inspection videos focusing on key product lines, successfully visualizing service processes and building industry benchmarks [10][12] - Danaher Group has integrated its sub-brands to provide comprehensive service coverage across various fields, showcasing a collaborative service model [14][16] Group 3: Domestic Brands and Innovations - Domestic brands like Puxi and Leici are shifting from reactive to proactive service strategies, with Puxi hosting live training sessions to address user queries [25][27] - New entrants like Tianmei and Yuanxi are showcasing their service capabilities through on-site inspections and interactive content [29] Group 4: Value Creation and Marketing - The article outlines three core values that drive long-term brand growth: building brand trust through real service scenarios, reaching high-intent users, and establishing differentiated service reputations [34] - Jenoptik emphasizes the importance of high-quality service alongside product quality, aiming to transform every interaction into a trust-building opportunity [21]

2017年，WHO推荐升级版Xpert MTB/RIF Ultra，检测灵敏度进一步提升，尤其适用于痰涂片阴性和儿童结核病。 2024年12月5日，WHO正式预认证Xpert MTB/RIF Ultra，这是首个符合WHO全部质量、性能和安全标准的结核 病诊断和抗生素敏感性检测工具。 时至今日，核酸扩增技术正沿着 提升速度 、 简化操作 、 降低污染 及 拓展应用场景 的方向持续发展，并与多种前 沿技术深度融合，在医疗诊断、生物信息等领域展现出巨大潜力。尽管部分前沿探索仍处于研究阶段，但其发展方向已 清晰可见： 点击免费限量礼盒 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 2010年12月8日。 世界卫生组织 (WHO) 正式批准并推荐使用Xpert MTB/RIF，这是一种 全自动核酸扩增检测技术 (NAAT)， 将结 核 病诊断时间从3个月缩短至100分钟，这种 全自动核酸扩增检测仪器系统 融合DNA技术与全自动操作流程，被纳入全 球结核病防控项目，推动传染病快速检测技术规模化应用。 Xpert MTB/RIF是由美国Cepheid ...

→点击免费限量礼盒 摘要 ： 12月3日，中国科学院与科睿唯安公司面向全球发布年度《2025研究前沿》，遴选出11大学科领域的TOP10热点前沿和18 个新兴前沿。 此次遴选涵盖农业科学、植物学和动物学，生态与环境科学，地球科学，临床医学，生物科 学，化学与材料科学，物理学，天文学与天体物理学，数学，信息科学，经济学、心理学及其他社会科学等11个高度 聚合的大学科领域。 化学与材料科学领域Top10热点前沿主要分布在合成化学、材料回收与循环利用、锂电池、 能源材料等研究方向。 | 合成化学方向有四项，涉及药物化学（ | | 苯环的生物电子等排体合成 | | --- | --- | --- | | ）、光化学（ | COF光催化合成过氧化氢 | ）、电化学（ | | 电化学还原二氧化碳制多碳产物 | ）、生物化学（ | ET水解酶的定向进化与 | | 设计 ）。 | | | 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 12月3日，中国科学院与科睿唯安公司面向全球发布年度《2025研究前沿》，报告以文献计量 学中的共被引分析方法为基础，研究 ...

Group 1 - Agilent and Sartorius are deepening their presence in China with localized products [3] - Thermo Fisher and Rigaku have launched new products [3] - BGI Genomics has opened a customer experience center in Singapore, furthering its globalization efforts [3]

Core Insights - The article emphasizes the importance of advancing high-end instruments and key core technologies as part of China's 15th Five-Year Plan [3][4][5] Group 1: National Strategy - The Ministry of Science and Technology highlighted the need for a full-chain approach to tackle key core technologies in high-end instruments [3] - The central government has issued strategic directives to enhance technological innovation across various sectors, including high-end instruments, advanced materials, and biomanufacturing [4] Group 2: Regional Policies - Shandong Province's plan includes accelerating major technological innovation projects and overcoming critical common technologies in fields such as high-end instruments and advanced manufacturing [4] - Guangdong Province aims to strengthen strategic technological support and achieve breakthroughs in key areas like integrated circuits and high-end instruments through a robust laboratory system [4] - Chongqing's strategy focuses on cultivating emerging industries, particularly in smart medical equipment and instrumentation, to promote large-scale development of strategic emerging industry clusters [5]