2025 年干眼症治疗药物 品牌推荐 市场规模·····十大品牌·排行榜 | 一、市场背景 2 | | --- | | 1.1 摘要 2 | | 1.2 干眼症定义 2 | | 1.3 市场演变 2 | | 二、市场现状 3 | | 2.1 市场规模 3 | | 2.2 市场供需 3 | | 三、市场竞争 4 | | 3.1 市场评估维度 4 | | 3.2 市场竞争格局 4 | | 3.3 十大品牌推荐 4 | | 四、发展趋势 6 | | 4.1 市场规模持续增长 6 | | 4.2 药物创新多元化发展 7 | | 4.3 本土企业崛起与全球化布局 7 | | 4.4 竞争格局与风险应对 7 | 2025 年干眼症治疗药物品牌推荐 一、市场背景 1.1 摘要 随着公众对视觉健康关注度的提升，干眼症已从职场及老年群体的"专属困扰"，演变为 覆盖全年龄段的慢性眼部健康挑战。2024 年中国干眼症患病人数已达 3.6 亿，但治疗率 仅 10%-12%，市场潜力巨大。制剂技术与给药系统革新推动药物从传统人工泪液向多剂 量无防腐剂制剂、新型递药途径升级，以环孢素滴眼液、全氟己基辛烷眼用制剂等为代 表的新机制疗法成为 ...

智通财经APP获悉，华润啤酒-R(80291)、京东集团-SWR(89618)、友邦保险-R(81299)上一交易日沽空比 率位于前三位，分别为100.00%、92.61%、82.83%。美团-W(03690)、小米集团-W(01810)、腾讯控股 (00700)的沽空金额位居前三，分别为18.99 亿元、12.48 亿元、12.23 亿元。远大医药(00512)、越秀地产 (00123)、中粮家佳康(01610)的偏离值位居前三，分别为42.04%、40.19%、39.65%。 | 股票名称 | 沽空金额 | 沽空比率 | 偏离值↓ | | --- | --- | --- | --- | | 远大医药(00512) | 333.14 万元 | 53.62% | 42.04% | | 越秀地产(00123) | 1028.89 万元 | 56.01% | 40.19% | | 中粮家佳康(01610) | 632.42 万元 | 50.01% | 39.65% | | 融创服务(01516) | 240.14 万元 | 64.63% | 39.64% | | 中国船舶租赁(03877) | 1212.09 万 ...

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2026年1月31日 狀態: 新提交 致：香港交易及結算所有限公司 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 00512 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 100,000,000,000 | HKD | | 0.01 | HKD | | 1,000,000,000 | | 增加 / 減少 (-) | | | | | | | HKD | | | | 本月底結存 | | | 100,000,000,000 | HKD | | 0.01 | HKD | | 1,000,000,000 | 本月底法定/註冊股本總額： HKD 1,000,000,000 第 ...

Grand Pharmaceutical Group Limited 遠大醫藥集團有限公司* ( 於百慕達註冊成立之有限公司 ) (股份代號: 00512) 補充及澄清公告 關連交易 收購河北遠大九孚生物科技有限公司及 保定加合精細化工有限公司全部股權 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準 確性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生 或因倚賴該等內容而引致的任何損失承擔任何責任。 茲提述本公司於二零二五年十二月三十一日刊發有關股份購買協議項下擬進行交易之關連 交易之公告（「該公告」）。除另有說明外，本補充公告所用詞彙與該公告所界定者具 有相同涵義。 誠如公告所披露，本次交易之代價人民幣 316,000,000 元乃經買方與賣方參考下列因素後， 經公平磋商釐定：(i)目標公司之財務表現、業務增長及前景（包括現有資產、研發進程中 之技術專長及研發項目之未來前景）； (ii) 獨立合資格估值師根據市場法編製之估值報告， 據此，於扣除建議向賣方分派之利潤人民幣 134,000,000元後，目標公司 100%股權於 2025 年 9 月 30 ...

Market Performance - The Hong Kong stock market experienced a decline, with the Hang Seng Index falling by 0.29% to 26,487.51 points, the Hang Seng Tech Index down 1.16% to 5,683.44 points, and the National Enterprises Index decreasing by 0.43% to 9,094.76 points [1] - Major technology stocks generally declined, with Alibaba down 0.44%, Tencent down 1.48%, and Xiaomi down 2.74%, while JD.com saw a slight increase of 0.09% [1] - New consumption concept stocks performed well, with Pop Mart rising by 9% and Naixue's Tea increasing by over 4% [1] Corporate News - Codex-B (02487.HK) reported positive top-line results from a Phase III clinical trial for CU-20101, an injectable botulinum toxin type A for moderate to severe glabellar lines [2] - Saint Bella (02508.HK) entered a strategic cooperation framework agreement with Cloudwise Technology to explore the integration of AI and robotics in high-demand home care scenarios [2] Profit Forecasts - China Taiping (00966.HK) expects a net profit increase of approximately 215% to 225% in 2025, compared to 8.432 billion HKD in the previous year [3] - TCL Electronics (01070.HK) anticipates an adjusted net profit of approximately 2.33 billion to 2.57 billion HKD in 2025, representing a growth of 45% to 60% [3] - Jihong Co. (02603.HK) forecasts a net profit of approximately 273 million to 291 million RMB in 2025, a year-on-year increase of 50% to 60% [3] - Guolian Minsheng (01456.HK) expects a net profit of 2.008 billion RMB in 2025, a growth of around 406% [3] - China Railway (00390.HK) reported a new contract amount of 1,165.98 billion RMB in Q4 2025, with a cumulative new contract amount of 2,750.9 billion RMB, a year-on-year growth of 1.3% [3] Sales and Revenue - Shenzhen Holdings (00604.HK) anticipates a total contract sales amount of approximately 13.311 billion RMB in 2025, a decrease of 21.55% [4] - SF Holding (06936.HK) reported a total revenue of 27.339 billion RMB in December from its logistics, supply chain, and international businesses, reflecting a year-on-year growth of 3.41% [5] Institutional Insights - Dongwu Securities noted that the Hong Kong market is in a long-term upward trend but faces short-term challenges, with strong consensus on domestic fundamentals but mixed views on overseas factors [9] - Huaxia Fund emphasized the high sensitivity of the Hong Kong market to corporate earnings and macroeconomic data, suggesting that positive economic surprises could significantly boost market expectations [10] - Tianfeng Securities highlighted that the Hong Kong market has the foundation for a rebound due to valuation recovery and sentiment improvement, but upward momentum may be constrained by high overseas interest rates [10] - Huaxi Securities pointed out that the "AI+" logic is catalyzing valuation optimization in the Hong Kong market, with a focus on internet, technology, and emerging consumption sectors [10]

Core Viewpoint - The announcement by Yuan Da Pharmaceutical regarding the acceptance of its new drug application for the innovative radiopharmaceutical conjugate drug TLX591-CDx marks a significant advancement in the field of nuclear medicine for cancer diagnosis, particularly for prostate cancer patients in China [1]. Company Summary - Yuan Da Pharmaceutical has submitted a new drug application (NDA) for TLX591-CDx to the National Medical Products Administration, which has been accepted [1]. - This development is expected to enhance the company's product pipeline in the nuclear medicine sector, specifically targeting tumor diagnosis [1]. Industry Summary - The acceptance of TLX591-CDx signifies the introduction of a globally leading precision diagnostic tool for prostate cancer, which could facilitate early detection, precise classification, and optimization of treatment plans for patients [1].

Group 1: Major Developments - 康耐特光学 (02276) and 歌尔光学 plan to establish a joint venture to expand the application market for customized lenses in AI/AR/VR/MR glasses [1] - 圣贝拉 (02508) and 云迹科技 signed a strategic cooperation framework agreement to explore the deep integration and application of artificial intelligence and robotics in high-demand home care scenarios [1] - KKCG Maritime intends to initiate a voluntary conditional partial public acquisition offer to acquire 15.4% of 法拉帝 (09638) shares [1] - 远大医药 (00512) announced that the new drug application for the innovative radiolabeled drug TLX591-CDx has been accepted by the China National Medical Products Administration [1] - 艾美疫苗 (06660) received approval to conduct clinical trials for a 20-valent pneumococcal polysaccharide conjugate vaccine [1] - 中国东方航空股份 (00670) sold the 凯迪克大厦 in Shanghai and related assets to 东航置业 for approximately 134 million yuan [1] - 佑驾创新 (02431) signed a memorandum of understanding with India's leading automotive parts manufacturer STL [1] - 南山铝业国际 (02610) plans to develop electrolytic aluminum and related raw materials and supporting businesses [1] Group 2: Financial Performance - 顺丰控股 (06936) reported a total revenue of 27.339 billion yuan from its express logistics, supply chain, and international businesses in December, representing a year-on-year increase of 3.41% [2] - 美丽田园医疗健康 (02373) issued a profit warning, expecting adjusted net profit for 2025 to be no less than 380 million yuan, a year-on-year increase of at least 40% [2] - 中国太平 (00966) issued a profit warning, anticipating a year-on-year increase of approximately 215% to 225% in shareholder profit for the 2025 fiscal year [2] - 吉宏股份 (02603) issued a profit warning, expecting a net profit attributable to shareholders of approximately 273 million to 291 million yuan for 2025, a year-on-year increase of 50% to 60% [2] - 兖煤澳大利亚 (03668) reported a fourth-quarter coal sales volume of 10.8 million tons, a year-on-year increase of 4% [2] - 兖矿能源 (01171) reported a fourth-quarter commodity coal production of 46.51 million tons, a year-on-year increase of 4.4% [2] - 深圳控股 (00604) projected a total contract sales amount of approximately 13.311 billion yuan for 2025, a year-on-year decrease of 21.55% [2] - 上海石油化工股份 (00338) issued a profit warning, expecting a net loss attributable to shareholders of approximately 1.289 billion to 1.576 billion yuan for 2025, indicating a shift from profit to loss [2] - 上海石油化工股份 (00338) reported gasoline sales revenue of 24.656 billion yuan for 2025 [2]

Core Viewpoint - The acceptance of the new drug application (NDA) for TLX591-CDx by the National Medical Products Administration marks a significant advancement for the company in the field of nuclear medicine for cancer diagnosis [1][2]. Group 1: Product Development and Market Potential - TLX591-CDx is a diagnostic radiopharmaceutical targeting prostate-specific membrane antigen (PSMA), suitable for diagnosing both newly diagnosed and recurrent prostate cancer [1]. - The NDA application includes data from a clinical study conducted in China, which is a Phase III open-label study involving over 100 patients with biochemical recurrence of prostate cancer [1]. - The incidence of prostate cancer in China is on the rise, with projections indicating nearly 200,000 new cases by 2030 according to Frost & Sullivan data [1]. Group 2: Commercial Performance and Expansion - TLX591-CDx has been approved for commercialization in 24 countries, including Australia, the USA, and several European nations, demonstrating strong commercial performance with sales of approximately $517 million in 2024 and $461 million in the first three quarters of 2025, reflecting a year-on-year growth of over 25% [2]. - The acceptance of the NDA is a crucial step in the company's strategy to build an integrated diagnostic and therapeutic product portfolio for prostate cancer, with the complementary therapeutic product TLX591 already approved for international Phase III clinical studies in China [2]. Group 3: Strategic Positioning and Future Outlook - The company has established a comprehensive layout in the nuclear medicine sector, covering research and development, production, distribution, and sales [2]. - The ongoing "Go Global" strategy and the anticipated launch of TLX591-CDx and other innovative products are expected to enhance the company's core competitiveness in the nuclear medicine field [2].

北京商报讯（记者 王寅浩 宋雨盈）1月19日，远大医药发布公告称，公司用于诊断前列腺癌的创新在研 放射性核素偶联药物TLX591-CDx近日正式向中华人民共和国国家药品监督管理局递交了新药上市申请 并获得了受理。根据公告，TLX591-CDx是一款全球创新、基于放射性核素-小分子偶联技术的靶向前列 腺特异性膜抗原的诊断型放射性药物，适用于初诊和复发性前列腺癌的诊断。 ...

Core Viewpoint - The acceptance of the new drug application (NDA) for TLX591-CDx by the National Medical Products Administration marks a significant advancement for the company in the nuclear medicine field, particularly for prostate cancer diagnosis, providing a leading-edge tool for early detection and treatment optimization [1][12]. Group 1: Market Potential and Clinical Data - Prostate cancer is increasingly prevalent in China, with an expected 200,000 new cases by 2030 and a market size projected to grow at a compound annual growth rate (CAGR) of approximately 21.8% to nearly 50.6 billion RMB [2][4]. - The overall positive predictive value (PPV) of TLX591-CDx in detecting tumors is reported at 94.8%, demonstrating its effectiveness compared to non-Chinese patient studies [9]. - Over 67.2% of patients had their treatment plans adjusted after undergoing PET imaging with TLX591-CDx, indicating its significant impact on clinical decision-making [9]. Group 2: Product Advantages and Technology - TLX591-CDx features a unique design with the PSMA-11 targeting agent, which binds specifically to PSMA expressed in prostate cancer, ensuring high diagnostic precision and safety [10][11]. - The product's characteristics include precise targeting, efficient imaging, and reliable safety, fulfilling clinical needs for early diagnosis and monitoring of prostate cancer [11]. Group 3: Strategic Development and Global Positioning - The acceptance of TLX591-CDx's NDA is a crucial step in the company's strategy to build an integrated diagnostic and therapeutic nuclear medicine product portfolio for prostate cancer [12]. - The company has established a comprehensive global layout in the nuclear medicine sector, with R&D and production bases in Boston and Chengdu, and a sales network covering over 50 countries [13]. - The company has a pipeline of 16 innovative products, including both diagnostic and therapeutic nuclear medicine options, aimed at various cancer types, enhancing its competitive edge [13]. Group 4: Future Outlook and Expansion - The successful international approval of the company's innovative small molecule RDC drug GPN01530 for clinical research signifies its strong clinical development capabilities and potential for future cancer imaging standards [16]. - The Chengdu production base, equipped with 14 high-standard GMP production lines, enables the company to meet diverse production needs and reduce reliance on imports, enhancing its operational efficiency [16]. - The ongoing "Go Global" strategy and the launch of innovative products like TLX591-CDx are expected to strengthen the company's competitive position in the global nuclear medicine market [17].