Core Viewpoint - The company has received a drug registration certificate from the National Medical Products Administration for a nebulized solution of Terbutaline Sulfate, which is intended to alleviate bronchial asthma, chronic bronchitis, emphysema, and other lung diseases associated with bronchospasm [1] Company Summary - The approved product is a nebulized solution of Terbutaline Sulfate, which targets respiratory conditions [1] - The cumulative R&D investment for this drug has reached approximately 5.0111 million RMB [1]

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重 大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 近日，浙江莎普爱思药业股份有限公司（以下简称 "公司"、"莎普爱思"）收 到国家药品监督管理局核发的硫酸特布他林雾化吸入用溶液的《药品注册证书》（证书 编号：2025S02611），现将有关信息公告如下： 证券代码：603168 证券简称：莎普爱思 公告编号：临 2025-048 浙江莎普爱思药业股份有限公司 关于获得硫酸特布他林雾化吸入用溶液 《药品注册证书》的公告 审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品符合药 品注册的有关要求，批准注册，发给药品注册证书。 二、药品其他情况 本次获批的硫酸特布他林雾化吸入用溶液，可缓解支气管哮喘、慢性支气管炎、肺 气肿及其它肺部疾病所合并的支气管痉挛。 一、《药品注册证书》主要内容 药品名称：硫酸特布他林雾化吸入用溶液 剂型：吸入制剂 规格：2ml：5mg 注册分类：化学药品4类 药品批准文号：国药准字H20255228 上市许可持有人：浙江莎普爱思药业股份有限公司 截至本公告披露日，公司针对该药品的累计研发投入约 ...

莎普爱思（603168）(603168.SH)公告，公司收到国家药品监督管理局核发的硫酸特布他林雾化吸入用 溶液的《药品注册证书》。本次获批的硫酸特布他林雾化吸入用溶液，可缓解支气管哮喘、慢性支气管 炎、肺气肿及其它肺部疾病所合并的支气管痉挛。 ...

Core Viewpoint - The company received a drug registration certificate from the National Medical Products Administration for a new medication, which is expected to alleviate respiratory conditions such as bronchial asthma and chronic bronchitis [1] Company Summary - The newly approved medication is a sulfate terbutaline aerosol inhalation solution [1] - This drug is indicated for the relief of bronchospasm associated with bronchial asthma, chronic bronchitis, emphysema, and other pulmonary diseases [1]

Core Viewpoint - The company has received a drug registration certificate from the National Medical Products Administration for its nebulized solution of Terbutaline Sulfate, which is intended to alleviate bronchial asthma, chronic bronchitis, emphysema, and other lung diseases associated with bronchospasm [1] Group 1 - The approved product is a nebulized solution of Terbutaline Sulfate [1] - The solution is indicated for the relief of bronchial asthma and other respiratory conditions [1]

Core Viewpoint - The recent surge in A-share ophthalmology stocks is driven by the news of the discontinuation of a specific eye drop formulation, which has led to increased investor interest in alternative products and companies in the sector [1][2]. Company Developments - Shapuaisi (603168.SH) and Innovation Medical (002173.SZ) reached their daily limit up, while Xingqi Eye Medicine (300573.SZ) rose over 14%, and Baicheng Pharmaceutical (301096.SZ) increased by over 8% [1]. - Xingqi Eye Medicine's atropine eye drops have seen significant stock price increases following their approval for market release, with the stock reaching a historical high of 152.04 yuan per share on May 30, 2024 [2]. - In 2024, Xingqi Eye Medicine reported a revenue of 1.943 billion yuan, a year-on-year increase of 32.42%, and a net profit of 338 million yuan, up 40.84% [2]. Market Dynamics - The market for atropine eye drops is becoming increasingly competitive, with several companies, including Zhaoke Ophthalmology and Heng Rui Medicine, actively pursuing approvals for their own formulations [3]. - The discontinuation of the 0.01% atropine eye drops from Henan Provincial Eye Hospital is expected to create opportunities for other companies to capture market share [1][3]. - The ongoing development of new formulations, such as Xingqi Eye Medicine's upcoming SQ-729 eye drops, is anticipated to enhance the company's product offerings and performance [3].

Core Insights - The company reported a total revenue of 236 million yuan for the first half of 2025, with a net profit attributable to shareholders of 21.86 million yuan, an increase of 46.58 million yuan compared to the same period last year [1] - Operating cash flow showed a net inflow of 51.45 million yuan, which is an increase of 61.58 million yuan year-on-year [1] Financial Metrics - The latest debt-to-asset ratio stands at 23.32%, ranking 59th among disclosed peers, a decrease of 0.72 percentage points from the previous quarter [3] - The gross profit margin is reported at 60.30%, ranking 55th among peers, with an increase of 2.31 percentage points from the previous quarter and an increase of 8.85 percentage points year-on-year [3] - Return on equity (ROE) is at 1.36%, which is an increase of 2.82 percentage points compared to the same period last year [3] - The diluted earnings per share are 0.06 yuan, an increase of 0.13 yuan from the same period last year [3] - The total asset turnover ratio is 0.11 times, remaining flat year-on-year, while the inventory turnover ratio is 1.00 times [3] Shareholder Structure - The number of shareholders is 27,600, with the top ten shareholders holding a total of 192 million shares, accounting for 51.08% of the total share capital [3] - The largest shareholder is Shanghai Yanghe Industrial Co., Ltd., holding 20.82% of the shares [3]

Group 1 - The ophthalmology medical concept stocks experienced a surge during trading, with Sharplife reaching a limit up [1] - Xingqi Eye Medicine rose over 10% in the afternoon session [1] - Lifang Pharmaceutical previously hit the limit up, indicating strong market interest [1] Group 2 - Other companies such as Baicheng Pharmaceutical, Aibo Medical, Guangzheng Eye Care, and He Shi Eye Care also saw increases in their stock prices [1]

Policy Developments - Guangzhou's "Sui Xin Bao" has added 60 innovative drugs and 6 hospitals, enhancing its coverage to include local innovative drugs and those not covered by medical insurance [1] - Shandong Province has implemented a funding management method to support the consistency evaluation of generic drug quality and efficacy, offering up to 2 million yuan for qualifying products [2] Drug Approvals - Sanofi's covalent inhibitor Wayrilz (rilzabrutinib) has been approved by the FDA for treating adult patients with immune thrombocytopenia (ITP) [3] - Heng Rui Medicine's new drug Zemeituosita tablets has been approved, marking it as the first domestic EZH2 inhibitor for treating relapsed or refractory peripheral T-cell lymphoma [4] Financial Reports - Shanghai Laishi reported a revenue of 3.952 billion yuan for the first half of 2025, a decrease of 7.06%, with a net profit of 1.03 billion yuan, down 17% [5] - Beijing Tongrentang achieved a revenue of 9.769 billion yuan in the first half of 2025, with a net profit of 945 million yuan, a decrease of 7.39% [6][8] - Shapuaisi turned a profit with a net profit of 21.86 million yuan, recovering from a loss in the previous year [7] - Yixin Hall reported a revenue of 8.914 billion yuan, down 4.20%, with a net profit of 250 million yuan, down 11.44% [9] - Changchun High-tech reported a revenue of 6.603 billion yuan, down 0.54%, with a net profit of 983 million yuan, down 42.85% [10] Corporate Actions - Maiwei Biotech has re-submitted its application for H-share listing on the Hong Kong Stock Exchange [11] - Olin Biotech plans to acquire a 15% stake in its subsidiary Xin Nuo Ming Biotech to enhance control and management efficiency [12] - Meinian Health signed a cooperation framework agreement with Guofu Quantum and Jingbeifang to explore digital asset business in the health sector [13] Industry Events - Hainan Lecheng signed cooperation agreements with 13 leading biopharmaceutical companies, with expected total investments of no less than 3 billion yuan [14] - Novo Nordisk has invested up to $5.5 billion in a partnership with Replicate Bioscience to develop new therapies for metabolic diseases [15]

Core Viewpoint - The company reported a turnaround in profitability for the first half of 2025, achieving a net profit of 21.86 million yuan, driven by increased demand in ophthalmic and maternal-child healthcare markets, alongside supportive policy measures [1] Group 1: Financial Performance - In the first half of 2025, the company achieved operating revenue of 236.09 million yuan and a net profit of 21.86 million yuan, marking a significant improvement from the previous year [1] - The company has strengthened its research and development efforts and channel construction, leading to enhanced core business momentum [1] Group 2: Product Development and Innovation - The company focuses on the research, production, and sales of eye drops, large-volume infusions, and cefixime, while also expanding into ophthalmic and maternal-child healthcare, forming a dual-driven business model of "pharmaceuticals + medical services" [2] - Several products are progressing well in the research pipeline, with multiple eye drop formulations receiving drug registration certificates from the National Medical Products Administration [2] Group 3: Channel Development - The company has established a comprehensive marketing network across most provinces and cities in China, enhancing product penetration through a professional OTC marketing team [3] - The company is leveraging new media trends to build a broad and interactive communication matrix, thereby increasing brand influence [3] Group 4: Market Trends and Strategic Positioning - The company is capitalizing on the accelerating demand in the ophthalmic drug market, which is projected to reach 108.4 billion USD by 2030, driven by aging population and increasing vision issues among youth [4] - The company is focusing on a research-driven strategy in the ophthalmic field, with ongoing clinical trials for key products targeting common eye diseases [4] - The maternal-child healthcare sector is expected to grow due to favorable policies aimed at reducing childcare costs and enhancing support for families [4] Group 5: Future Outlook - The company aims to achieve business growth through the synergistic effect of its "pharmaceuticals + medical services" strategy, with ongoing product development and solid market resources [5]