Core Viewpoint - Seer Medical (603716) is actively engaging in a strategic investment in the healthcare sector, specifically focusing on the development of a therapeutic hypertension vaccine, which has received clinical trial approval and is preparing for Phase I trials [1] Group 1: Stock Performance - As of October 16, 2025, Seer Medical's stock closed at 25.88 yuan, down 3.65% from the previous trading day, with a total market capitalization of 5.439 billion yuan [1] - The stock opened at 26.04 yuan, reached a high of 26.98 yuan, and a low of 25.8 yuan, with a trading volume of 6.72 billion yuan and a turnover rate of 12.22% [1] Group 2: Investment and Development - Seer Medical received a regulatory work letter from the Shanghai Stock Exchange regarding related party investments and has responded to the inquiries [1] - The target company, Wuhan Huajiyuan, is developing the HJY-ATRQβ-001 injection, a therapeutic vaccine for hypertension, which has been approved for clinical trials and is currently preparing for Phase I trials [1] - Seer Medical plans to increase its investment by 42.7429 million yuan, resulting in a 41% ownership stake in the project, with the valuation based on the income approach [1] Group 3: Financials and Risks - Wuhan Huajiyuan has a net asset value of -43.8081 million yuan, with an assessed value of 274 million yuan, primarily driven by intangible assets [1] - The company emphasizes that the project follows the regularities of new drug development and possesses technical feasibility, but acknowledges risks such as long development cycles and significant capital investment [1] - Seer Medical has 135 million yuan in cash and plans to secure funding through financing and shareholder support to ensure the investment payment [1]

| 证券代码：603716 | 证券简称：塞力医疗 | 公告编号：2025-090 | | --- | --- | --- | | 债券代码：113601 | 债券简称：塞力转债 | | 塞力斯医疗科技集团股份有限公司 关于关联共同投资有关事项的监管工作函回复公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏,并对其内容的真实性、准确性和完整性承担法律责任。 重要风险提示： 研发进度缓慢风险：武汉华纪元生物技术开发有限公司（以下简称"武 汉华纪元"或"标的公司"）现阶段研发的 HJY-ATRQβ-001 注射液适用于治疗 轻中度原发性高血压，治疗性降血压疫苗项目严格遵循新药研发客观规律，当前 处于筹备Ⅰ期临床试验的关键阶段，产品研发后续还需经Ⅰ期、Ⅱ期临床试验， 试验能否成功存在重大不确定性。且标的公司尚未盈利，未来正式投产、销售时 间、销售收入及可能获得的投资回报尚难预测。 投资现金流及项目收益变现较难风险：本次投资对公司主营业务影响较 小，短期内没有可能产生收益，对公司现金流可能造成不利影响，且未来标的公 司股权出售或变现亦受多种因素影响，具有重大不确定性。 款项未能如 ...

Core Insights - The internet healthcare sector experienced a decline of 0.59% on October 16, with Rongke Technology leading the drop [1] - The Shanghai Composite Index closed at 3916.23, up 0.1%, while the Shenzhen Component Index closed at 13086.41, down 0.25% [1] Stock Performance - Notable gainers in the internet healthcare sector included: - Wanma Technology (300698) with a closing price of 50.09, up 10.94% and a trading volume of 237,000 shares, totaling 1.177 billion yuan [1] - Fengzhou Ziling (002424) at 5.95, up 9.98% with a volume of 482,600 shares, totaling 281 million yuan [1] - New Mileage (002219) at 2.45, up 9.87% with a volume of 3.4548 million shares, totaling 833 million yuan [1] - Decliners included: - Moke Technology (300290) at 22.16, down 8.54% with a volume of 435,700 shares, totaling 976 million yuan [2] - Zhongyuan Shares (300018) at 10.45, down 6.28% with a volume of 472,200 shares, totaling 500 million yuan [2] Capital Flow - The internet healthcare sector saw a net outflow of 702 million yuan from institutional investors, while retail investors contributed a net inflow of 343 million yuan [2][3] - Key stocks with significant capital flow included: - New Mileage (002219) with a net inflow of 1.59 billion yuan from institutional investors, but a net outflow from retail investors [3] - Wanma Technology (300698) with a net inflow of 146 million yuan from institutional investors [3]

Core Viewpoint - The pharmaceutical commercial sector experienced a decline of 0.27% on October 16, with Saily Medical leading the drop. The Shanghai Composite Index rose by 0.1%, while the Shenzhen Component Index fell by 0.25 [1][2]. Group 1: Market Performance - The pharmaceutical commercial sector's stocks showed mixed performance, with notable gainers including: - Jianfa Zhixin (301584) at 26.92, up 1.24% with a trading volume of 97,100 shares and a turnover of 262 million yuan - Yifeng Pharmacy (603939) at 24.41, up 1.12% with a trading volume of 75,400 shares and a turnover of 184 million yuan - Daclin (603233) at 17.31, up 1.11% with a trading volume of 96,800 shares and a turnover of 169 million yuan [1]. - Conversely, Saily Medical (603716) saw a significant decline of 3.65%, closing at 25.88 with a trading volume of 256,800 shares [2]. Group 2: Capital Flow - The pharmaceutical commercial sector experienced a net outflow of 243 million yuan from institutional investors, while retail investors saw a net inflow of 210 million yuan [2][3]. - Notable capital flows for specific stocks included: - Jianfa Zhixin (301584) with a net inflow of 15.55 million yuan from institutional investors, but a net outflow of 13.82 million yuan from retail investors [3]. - Baiyang Pharmaceutical (301015) had a net inflow of 10.41 million yuan from institutional investors, while retail investors experienced a net outflow of 11.76 million yuan [3].

Market Overview - On October 15, the AI medical sector rose by 2.05%, with Saili Medical leading the gains [1] - The Shanghai Composite Index closed at 3912.21, up 1.22%, while the Shenzhen Component Index closed at 13118.75, up 1.73% [1] Stock Performance - Saili Medical (603716) closed at 26.86, up 7.31% with a trading volume of 384,800 shares and a transaction value of 1.02 billion [1] - Meinian Health (002044) closed at 5.43, up 4.42% with a trading volume of 1,534,300 shares and a transaction value of 823 million [1] - Hongbo Pharmaceutical (301230) closed at 33.40, up 3.99% with a trading volume of 33,500 shares and a transaction value of 111 million [1] - Other notable stocks include Electric Science Digital (600850) up 3.79% and Yao Stone Technology (300725) up 3.45% [1] Capital Flow - The AI medical sector saw a net inflow of 189 million from institutional investors, while retail investors experienced a net outflow of 78.98 million [2][3] - Meinian Health had a net inflow of 88.56 million from institutional investors, but a net outflow of 93.20 million from retail investors [3] - Saili Medical also experienced a net inflow of 71.52 million from institutional investors, with retail investors withdrawing 32.95 million [3]

Market Overview - The SPD sector of medical consumables increased by 1.95% compared to the previous trading day, with Sely Medical leading the gains [1] - The Shanghai Composite Index closed at 3912.21, up 1.22%, while the Shenzhen Component Index closed at 13118.75, up 1.73% [1] Stock Performance - Sely Medical (603716) closed at 26.86, with a rise of 7.31% and a trading volume of 384,800 shares, amounting to a transaction value of 1.02 billion [1] - Other notable stocks include: - East China Pharmaceutical (000963) at 40.86, up 3.89% with a transaction value of 615 million [1] - Kangdelai (603987) at 9.21, up 2.33% with a transaction value of 80.62 million [1] - Longma Information (300288) at 13.95, up 1.90% with a transaction value of 54.30 million [1] Capital Flow - The SPD sector saw a net inflow of 40.98 million from main funds, while retail funds had a net inflow of 14.03 million [2] - Notably, speculative funds experienced a net outflow of 55.01 million [2] Individual Stock Capital Flow - Sely Medical had a main fund net inflow of 71.52 million, but speculative funds saw a net outflow of 38.57 million [3] - Other stocks with significant capital flow include: - Liuyou Group (603368) with a main fund net inflow of 9.20 million and a speculative fund net outflow of 12.49 million [3] - Guoxin Health (000503) with a main fund net inflow of 8.12 million and a speculative fund net inflow of 791,200 [3]

Market Overview - The pharmaceutical commercial sector increased by 1.0% on October 15, with Saili Medical leading the gains [1] - The Shanghai Composite Index closed at 3912.21, up 1.22%, while the Shenzhen Component Index closed at 13118.75, up 1.73% [1] Stock Performance - Saili Medical (603716) closed at 26.86, with a rise of 7.31% and a trading volume of 384,800 shares, amounting to a transaction value of 1.02 billion [1] - Baiyang Pharmaceutical (301015) rose by 4.16% to close at 27.28, with a trading volume of 49,900 shares and a transaction value of 134 million [1] - Huaren Health (301408) increased by 2.70% to close at 12.94, with a trading volume of 57,600 shares and a transaction value of 7.41 million [1] - Other notable stocks include Yiyang Pharmaceutical (2.28% increase) and Yaoyigou (1.87% increase) [1] Capital Flow - The pharmaceutical commercial sector saw a net inflow of 156 million from institutional investors, while retail investors experienced a net outflow of 1.04 billion [2] - The main stocks with significant net inflows include Saili Medical (71.52 million) and Shanghai Pharmaceutical (49.55 million) [3] - Retail investors showed a notable outflow from Shanghai Pharmaceutical, with a net outflow of 63.13 million [3]

Core Insights - The A-share market has seen a significant rally in innovative drug concept stocks, with notable increases in share prices for several companies [1] Group 1: Stock Performance - Guangxi Shengtang (广生堂) experienced a rise of approximately 18% [2] - Shutaishen (舒泰神) increased by over 12% [2] - Jimin Health (济民健康) and Anglikang (昂利康) both hit the 10% daily limit up [2] - Huahai Pharmaceutical (华海药业) rose by over 9% [2] - Frontier Biologics (前沿生物) increased by over 8% [2] - Hanyu Pharmaceutical (翰宇药业) saw a rise of over 7% [2] - Saily Medical (塞力医疗) and Jiuzhou Pharmaceutical (九洲药业) both increased by over 6% [2] Group 2: Market Capitalization and Year-to-Date Performance - Guangxi Shengtang has a market capitalization of 19.2 billion with a year-to-date increase of 269.02% [2] - Shutaishen has a market capitalization of 17.3 billion with a year-to-date increase of 389.07% [2] - Jimin Health has a market capitalization of 5.76 billion with a year-to-date increase of 61.56% [2] - Anglikang has a market capitalization of 8.31 billion with a year-to-date increase of 213.50% [2] - Huahai Pharmaceutical has a market capitalization of 31.4 billion with a year-to-date increase of 18.92% [2] - Frontier Biologics has a market capitalization of 5.544 billion with a year-to-date increase of 51.64% [2] - Hanyu Pharmaceutical has a market capitalization of 19.2 billion with a year-to-date increase of 68.35% [2] - Saily Medical has a market capitalization of 5.628 billion with a year-to-date increase of 270.91% [2] - Jiuzhou Pharmaceutical has a market capitalization of 18.5 billion with a year-to-date increase of 56.50% [2]

Core Viewpoint - The innovative drug concept stocks experienced a significant surge in early trading on October 15, with several companies reaching their daily price limits and notable increases in stock prices [1]. Group 1: Stock Performance - Angli康 reached the daily limit up, indicating strong investor interest [1]. - Guangshengtang saw a rise of over 10%, with a notable increase of 14.41% in its stock price [2]. - Other companies such as Saili Medical, Shutaishen, Rongchang Bio, and Lianhuan Pharmaceutical also experienced substantial gains, contributing to the overall positive trend in the innovative drug sector [1]. Group 2: Notable Stock Increases - Guangshengtang (300436) reported a stock increase of 116.94%, with a rise of 14.41% [2]. - Pinlikang (002940) increased by 41.20%, with a rise of 10.01% [2]. - Saili Medical (603716) saw a 27.12% increase, with an 8.35% rise [2]. - Shutaishen (300204) experienced a 34.77% increase, with a 7.88% rise [2]. - Jimin Health (603222) rose by 10.64%, with a 6.72% increase [2]. - Lianhuan Pharmaceutical (600513) increased by 20.21%, with a 6.37% rise [2]. - Rongchang Bio (688331) saw a 97.06% increase, with a 6.31% rise [2]. - Zhendong Pharmaceutical (300158) increased by 6.95%, with a 5.95% rise [2]. - Kangchen Pharmaceutical (035500) rose by 48.68%, with a 4.91% increase [2]. - Maiwei Niwu-U (688062) saw a 46.58% increase, with a 4.86% rise [2].

Group 1 - The core point of the news is that Sely Medical's stock price increased by 5.55% to 26.42 CNY per share, with a trading volume of 246 million CNY and a turnover rate of 4.62%, resulting in a total market capitalization of 5.553 billion CNY [1] - Sely Medical Technology Group Co., Ltd. is based in Wuhan, Hubei Province, and was established on February 23, 2004, with its listing date on October 31, 2016. The company's main business involves centralized marketing and service for medical testing, as well as the agency and independent research, production, and sales of in vitro diagnostic products [1] - The revenue composition of Sely Medical includes IVD business at 39.91%, SPD business at 38.01%, and pure sales at 22.08% [1] Group 2 - From the perspective of the top ten circulating shareholders, the Caitong Fund has one fund among the top shareholders of Sely Medical. The Caitong Advantage Industry Rotation Mixed A Fund (011201) entered the top ten circulating shareholders in the second quarter, holding 643,400 shares, which accounts for 0.34% of the circulating shares. The estimated floating profit today is approximately 894,300 CNY [2] - The Caitong Advantage Industry Rotation Mixed A Fund (011201) was established on February 9, 2021, with a latest scale of 536 million CNY. Year-to-date returns are 17.35%, ranking 4543 out of 8161 in its category; the one-year return is 8.66%, ranking 5742 out of 8015; and since inception, it has a loss of 28.59% [2]