Group 1: Key Insights on Companies - Cansino Biologics has a clear strategic pipeline for innovative drug development, shifting focus from fast-follow monoclonal antibodies to dual-target or tri-target antibodies from 2022 to 2023, and planning to introduce FIC tri-target antibodies starting in 2024 [1] - The company anticipates completing some business development collaborations for its pipeline by 2025, with a focus on overseas partnerships from PCC to IND stages [1] - The GB18 project aims to improve weight loss and enhance muscle and fat weight, with injections expected every 3-4 weeks, and is currently under IND review in both China and the US [1] - The GB12 project, utilizing AI technology in collaboration with Baidu, features a bispecific antibody targeting IL-4R and IL-31, with limited market competition [1] - Cansino's international sales revenue growth target is set at 200%-400%, leveraging its overseas commercialization platform for long-term business growth [1] Group 2: Key Insights on Industry Trends - Lattice Semiconductor is focusing on the development of computing hardware chips over the next 5-10 years, particularly in interconnect chips, benefiting from over 20 years of deep technical accumulation [2] - The demand for DDR5 memory interface chips is expected to surge due to trends in the AI industry, with MRCD/MDB chips anticipated to become preferred solutions for high-performance computing and AI applications [2] - The company is advancing its PCIe Switch chip development, leveraging its successful experience with PCIe Retimer chips, which are expected to see increased demand driven by AI server shipments and PCIe protocol iterations [2] - The market potential for CXL-related applications is significant, with the company planning to continue its R&D in memory interface chips, PCIe Retimer, and MXC chips [2] - The company has implemented a performance evaluation system for executives based on market capitalization, aligning management interests with shareholder interests [2]

Core Insights - Shangya Investment recently conducted research on a listed company, focusing on the innovative drug development pipeline of Kexing Pharmaceutical, which has a clear strategy for different stages of drug development [1] Group 1: Company Overview - Kexing Pharmaceutical has shifted its focus from Fast-follow monoclonal antibodies in 2022 to dual-target or triple-target antibodies in 2022-2023, with plans to develop FIC class triple-target antibodies starting in 2024 [1] - The company anticipates completing some business development collaborations for its pipeline by 2025, particularly focusing on overseas collaborations from PCC to IND stages [1] Group 2: Product Pipeline - The GB18 project aims to improve weight loss, muscle and fat weight, and exercise function, with injections expected every 3-4 weeks; the domestic IND has been accepted, and the US IND is under application [1] - The GB12 project, which targets IL-4R and IL-31, benefits from dual specificity antibody advantages and has a competitive edge in the market, utilizing AI technology in collaboration with Baidu Biotechnology [1] - The GB20 and GB24 projects focus on the TL1 target, providing synergistic effects for inflammation and fibrosis prevention, covering the entire disease course of IBD [1] Group 3: Market Strategy - The product Bai Zi has seen increasing order volumes since its sales began in the EU in August 2024, with production scheduled based on orders for 2025 [1] - Kexing Pharmaceutical is prioritizing the introduction of high-tech barrier products, advancing local operations of its overseas subsidiaries, and accelerating the registration and listing process [1] - The company aims for an export revenue growth target of 200%-400%, relying on its overseas commercialization platform for long-term business growth [1]

Market Overview - The A-share market indices continued to rise, achieving a five-day consecutive increase, with a total trading volume of 1.31 trillion yuan, a decrease of 78 billion yuan from the previous trading day [1] - The Hainan sector experienced significant growth, while a few sectors such as shipping ports and the茅指数 saw declines [1] Stock Performance - A total of 103 stocks hit the daily limit, with 13 stocks achieving consecutive limit-ups, and 31 stocks failed to close at the limit, resulting in a limit-up rate of 77% (excluding ST and delisted stocks) [3] - Notable stocks included: - Guofang Group achieved a 7-day limit-up, driven by retail and brokerage investments [4] - Zhongqi New Material saw a 10.01% increase, marking its 9th day with 7 limit-ups, influenced by semiconductor equipment [4] - Zhongyuan Home achieved a limit-up, marking its 5th consecutive limit-up, supported by the sofa and e-commerce sectors [4] Institutional Trading - The top three net buying stocks on the Dragon and Tiger list were Hunan Gold, Tianhe Magnetic Materials, and Yuekang Pharmaceutical, with net purchases of 179 million yuan, 157 million yuan, and 106 million yuan, respectively [6] - The top three net selling stocks were Baolingbao, Hongbaoli, and Ouyagu, with net sales of 64.35 million yuan, 54.92 million yuan, and 46.72 million yuan, respectively [6] Sector Highlights - Hunan Gold's stock price surged due to rising gold prices, with spot gold breaking historical highs at $3,245.45 per ounce, and forecasts from Goldman Sachs and UBS predicting further increases [7] - Yuekang Pharmaceutical reported a 42.2 million yuan R&D investment in 2024, accounting for 11.16% of its revenue, reflecting a 0.78 percentage point increase year-on-year [12] - Baolingbao's stock experienced abnormal fluctuations, with a cumulative increase of over 20% in three consecutive trading days, while the company maintains a diverse product range in functional sugars [13] Notable Stock Movements - Kexing Pharmaceutical saw a significant increase of 16.83%, with a trading volume of 288 million yuan and a net institutional purchase of 89.31 million yuan [16] - Ha Sanlian's stock rose by 3.01%, with a trading volume of 787 million yuan and a net institutional purchase of 49.39 million yuan [16] - Qingdao Jinwang's stock increased by 5.41%, with a trading volume of 2.6 billion yuan and a net institutional purchase of 44.02 million yuan [16]

证券代码：688136 证券简称：科兴制药 公告编号：2025-020 科兴生物制药股份有限公司 股票交易异常波动公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 科兴生物制药股份有限公司（以下简称"公司"）股票连续三个交易日 内（2025 年 4 月 10 日、4 月 11 日、4 月 14 日）收盘价格涨幅偏离值累计超过 30%，属于股票交易异常波动。 经公司自查，并向公司控股股东、实际控制人进行书面询证，截至本公 告披露日，确认不存在关于公司的应披露而未披露的重大事项，公司日常经营情 况正常，未发生重大变化，所处的行业政策未发生重大调整。 公司股价短期波动幅度较大，公司特别提醒广大投资者，注意投资风险、 理性决策、审慎投资。 一、股票交易异常波动的具体情况 公司股票连续三个交易日内（2025 年 4 月 10 日、4 月 11 日、4 月 14 日） 收盘价格涨幅偏离值累计超过 30%，根据《上海证券交易所科创板股票异常交易 实时监控细则》的有关规定，属于股票交易异常波动的情形。 二、公司关注并核实的 ...

特此回函! 关于《科兴生物制药股份有限公司股票交易异常波动询证函》的回函 8 实际控制人: 1225 科兴生物制药股份有限公司: 贵公司发出的《科兴生物制药股份有限公司股票交易异常波动询证函》已收 悉，经过认真自查，现就有关情况回复如下： 截至本函签署日,本人作为贵公司的实际控制人,不存在影响贵公司股票交 易异常波动的重大事项,不存在其他应披露而未披露的重大信息,包括但不限于 筹划并购重组、股份发行、债务重组、业务重组、资产剥离和资产注入等对贵公 司股票交易价格产生较大影响的重大事项。本人在贵公司本次股票交易异常波动 期间未买卖贵公司股票。 2025 年 4 月 14 日 ...

关于《科兴生物制药股份有限公司股票交易异常波动询证函》的回函 科兴生物制药股份有限公司: 贵公司发出的《科兴生物制药股份有限公司股票交易异常波动询证函》已收 悉,经过认真自查,现就有关情况回复如下: 深圳科益医药 202 一、截至目前,本企业不存在除在指定媒体上已公开披露的信息以外影响贵 公司股票交易价格异常波动的重大事宜; 二、截至目前,本企业不存在处于筹划阶段的涉及贵公司的重大事项,包括 但不限于重大资产重组、股份发行、上市公司收购、债务重组、业务重组、资产 剥离、资产注入等重大事项; 三、在本次股票交易异常波动期间,本企业不存在买卖贵公司股票的情形。 特此回函! ...

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 会议召开时间：2025 年 04 月 23 日 （星期三） 15:00-17:00 会 议 召 开 地 点 ： 上 海 证 券 交 易 所 上 证 路 演 中 心 （ 网 址 ： https://roadshow.sseinfo.com/） 证券代码：688136 证券简称：科兴制药 公告编号：2025-021 科兴生物制药股份有限公司 关于参加 2024 年度科创板生物制品及 CXO 行业 集体业绩说明会的公告 会议召开方式：上证路演中心网络互动 投资者可于 2025 年 04 月 16 日（星期三）至 04 月 22 日（星期二）16:00 前登录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 ir@kexing.com 进行提问。公司将在说明会上对投资者普遍关注的问题进行回答。 科兴生物制药股份有限公司（以下简称"公司"）已于 2025 年 4 月 11 日发布 公司 2024 年度报告，为便于广大投资者更全面深入地了解公司 2024 年度经营成 ...

截至2025年4月14日 14:12，上证科创板综合指数(000680)上涨0.61%，成分股悦康药业(688658)上涨 19.91%，科兴制药(688136)上涨16.90%，华丰科技(688629)上涨11.72%，路德环境(688156)上涨8.36%， 南亚新材(688519)上涨8.04%。 数据显示，截至2025年3月31日，上证科创板综合指数(000680)前十大权重股分别为海光信息(688041)、 寒武纪(688256)、中芯国际(688981)、金山办公(688111)、中微公司(688012)、传音控股(688036)、联影 医疗(688271)、百利天恒(688506)、澜起科技(688008)、晶科能源(688223)，前十大权重股合计占比 22.34%。 科创综指ETF鹏华(589680)，场外联接A：023757；联接C：023758。 以上内容与数据，与界面有连云频道立场无关，不构成投资建议。据此操作，风险自担。 申万宏源证券指出，AI产业链持续突破——国产算力突围×物理智能革命×机器人量产元年，市场每次 回调都是筹码再沉淀。后续AI产业链催化节点或集中在5-6月，届时阿里、 ...

Investment Rating - The report maintains a "Recommendation" rating for Kexing Pharmaceutical (688136.SH) [3][10] Core Viewpoints - Kexing Pharmaceutical achieved a revenue of 1.407 billion yuan in 2024, representing an increase of 11.75%, and turned a profit with a net profit of 31 million yuan [4][7] - The company plans to distribute a cash dividend of 0.8 yuan per 10 shares to all shareholders [4] - The overseas sales revenue is expected to grow significantly, with a projected increase of 62% in 2024 [7] - The company is focusing on new emerging markets and has submitted over 120 registration applications for its products in more than 60 countries [7] - Kexing's innovative drug pipeline is progressing, with multiple projects in clinical trials, including two in Phase III [8] Summary by Sections Financial Performance - In 2024, Kexing Pharmaceutical reported a revenue of 1.407 billion yuan, up 11.75% from the previous year, and a net profit of 31 million yuan [4][7] - The company’s operating expenses showed a decrease in sales expense ratio by 12.33 percentage points to 42.42% [7] - The R&D expense ratio decreased by 15.45 percentage points to 11.94% due to reduced clinical and trial costs [7] Market Expansion - The company’s flagship product, albumin paclitaxel, received EU approval in July 2024, with increasing sales orders [7] - Kexing is targeting emerging markets, achieving over 15% sales growth in these regions during the reporting period [7] Innovation Pipeline - Kexing is advancing several projects in clinical trials, including GDF15 monoclonal antibody and dual-specific antibodies targeting VEGF/ANG-2 and IL-4R/IL-31 [8] - The GDF15 project is aimed at treating cancer cachexia and has received IND application acceptance from the Chinese regulatory authority [8] Future Projections - Revenue forecasts for 2025-2027 have been adjusted to 1.935 billion, 2.288 billion, and 2.807 billion yuan respectively [8] - Net profit projections for the same period are revised to 123 million, 243 million, and 357 million yuan respectively [8]

科兴制药 20250412 摘要 Q&A 科兴制药 2024 年的业绩表现如何？ 科兴制药 2024 年实现了稳健的收入增长和利润扭亏为盈。全年收入达 14 亿元， 同比增长 12%。其中，第四季度收入为 3.17 亿元，同比增长 27%。海外销售收 入为 2.2 亿元，同比增长 60%。扣除非经营性因素后的净利润为 3,500 万元， 息税前折旧摊销利润为 2.04 亿元，同比增长 200%以上。此外，经营净现金流 也从负数转正，实现了 1 亿元。 • 科兴制药 2024 年总收入达 18.5 亿元，同比增长 60%，扣非净利润 3,500 万元，息税前折旧摊销利润 2.04 亿元，增长超 200%，经营净现金流转正 至 1 亿元。海外销售增长 60%，主要受益于白介素在欧盟的销售增长。 • 科兴制药国内市场销售收入 11.8 亿元，集采影响下销量保持稳定增长，显 示国内市场基本盘稳固。海外市场通过引进 16 个新产品，设立覆盖多区域 的分支机构，积极推进本地化运营，增强营销能力。 • 科兴制药 2024 年研发费用保持约 10 亿元高位，临床三期研发投入较大。 公司围绕抗体和蛋白技术平台布局创新产品，如儿 ...