股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年5月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 麗珠醫藥集團股份有限公司 呈交日期: 2025年6月3日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01513 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 307,052,417 | RMB | | 1 RMB | | 307,052,417 | | 增加 / 減少 (-) | | | -7,245,300 | | | RMB | | -7,245,300 | | 本月底結存 | | | 299,807,117 | RMB | | 1 RMB | | 299,807,117 | 本月底法定/註冊股本總額： ...

证券代码：000513、01513 证券简称：丽珠集团、丽珠医药 公告编号：2025-046 根据回购本公司 H 股的一般授权，公司将通过香港联合交易所有限公司进 行场内回购，每次回购价格不高于相关回购日前 5 个交易日平均收盘价的 5%， 回购的 H 股股份将用于注销减少注册资本。 于 2025 年 5 月 14 日，已回购的公司 H 股股份共计 7,245,300 股已完成注 销。截至目前，本次回购 H 股的一般授权下，尚未进行 H 股回购。 丽珠医药集团股份有限公司关于回购公司股份的进展公告 本公司及董事会全体成员保证信息披露内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 丽珠医药集团股份有限公司（以下简称"公司"）于 2024 年 12 月 24 日召 开了公司 2024 年第四次临时股东大会、2024 年第二次 A 股类别股东会及 2024 年第二次 H 股类别股东会，审议通过了《关于回购公司部分 A 股股份方案的议 案》，于 2025 年 5 月 29 日召开了公司 2024 年度股东大会、2025 年第一次 A 股 类别股东会及 2025 年第一次 H 股类别股东会，审议通过了《关 ...

证券代码：000513、01513 证券简称：丽珠集团、丽珠医药 公告编号：2025-045 丽珠医药集团股份有限公司 2024 年度股东大会、2025 年第一次 A 股类别股东会及 2025 年 第一次 H 股类别股东会决议公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 特别提示： 2024 年度股东大会、2025 年第一次 A 股类别股东会及 2025 年第一次 H 股 类别股东会没有出现否决议案的情形，未涉及变更以往股东大会已通过的决议。 一、会议的召集、召开和出席情况 1、股东大会届次：丽珠医药集团股份有限公司（以下简称"公司"）2024 年度股东大会、2025 年第一次 A 股类别股东会及 2025 年第一次 H 股类别股东 会。 2、股东大会的召集人：公司董事会。公司已于 2025 年 4 月 23 日召开了第 十一届董事会第二十四次会议，审议通过了《关于召开公司 2024 年度股东大会、 2025 年第一次 A 股类别股东会及 2025 年第一次 H 股类别股东会的议案》。 3、股东大会的主持人：副董事长陶德胜先生。 4、会议召开的合法、合 ...

广东德赛律师事务所 关于丽珠医药集团股份有限公司关于召开 2024 年度股东大会、 2025 年第一次 A 股类别股东会及 2025 年第一次 H 股类别股东会的 法 律 意 见 书 致：丽珠医药集团股份有限公司 受丽珠医药集团股份有限公司(下称"公司")之委托，广东德赛律师事务所 (下称"本所")指派王先东、谢翔律师(下称"本律师")，就公司 2024 年度股 东大会(下称"本次股东大会")、2025 年第一次 A 股类别股东会（下称"A 股类 别股东会"）及 2025 年第一次 H 股类别股东会（下称"H 股类别股东会"）的召 集、召开程序、出席会议人员资格、股东大会的表决程序、议案表决情况等相关 问题出具法律意见。 本法律意见书依据《中华人民共和国公司法》(下称《公司法》)、《中华人 民共和国证券法》(下称《证券法》)、《上市公司股东大会规则》(下称《规则》) 及《深圳证券交易所股票上市规则》等相关法律、法规、条例、规则的规定及《公 司章程》出具。 为出具本法律意见书之目的，本律师依照现行、有效的中国法律、法规及中 国证券监督管理委员会(下称"中国证监会")相关条例、规则的要求和规定，对 公司提供的与上 ...

Group 1 - The National Vaccine and Biotechnology Index (980015) has seen a strong increase of 2.39% as of May 29, 2025, with notable gains in constituent stocks such as Zhaoyan New Drug (603127) up 9.99%, Yifan Pharmaceutical (002019) up 9.17%, and Dizhe Pharmaceutical (688192) up 8.73% [1] - The Biovaccine ETF (159657) rose by 2.28%, with the latest price reported at 0.63 yuan [2] - The 2025 American Society of Clinical Oncology (ASCO) Annual Meeting will take place from May 30 to June 3, 2025, in Chicago, showcasing the development of oncology research in China, with over 70 studies from Chinese scholars selected for presentation [2] Group 2 - The top ten weighted stocks in the National Vaccine and Biotechnology Index (980015) as of April 30, 2025, include Fosun Pharma (600196), Changchun High-tech (000661), and others, collectively accounting for 63.18% of the index [3] - The Biovaccine ETF closely tracks the National Vaccine and Biotechnology Index, which consists of 50 companies involved in the biotechnology industry, reflecting the overall performance of quality listed companies in the sector [2]

Core Viewpoint - The acquisition of 64.81% stake in Imexpharm Corporation (IMP) by Lijuz Group for 1.587 billion yuan has sparked market discussions primarily due to its high valuation [1]. Group 1: Acquisition Details - The transaction price corresponds to a price-to-earnings (P/E) ratio of 27.6 times IMP's projected net profit for 2024, significantly higher than Lijuz Group's own P/E ratio of 15 times [4]. - If calculated based on the annualized net profit for the first quarter of 2025, the dynamic P/E ratio rises to 29.7 times [4]. - The acquisition price represents a premium of 293.79% over IMP's net assets at the end of 2024, indicating a control premium and a bet on the potential of the Vietnamese pharmaceutical market [4]. Group 2: Company Background and Market Position - IMP, established in 1977, is a leading pharmaceutical company in Vietnam, with core products including antibiotics (first in market share) and cardiovascular drugs (fifth in market share), covering over 80% of medical institutions in Vietnam [4]. - In 2024, IMP reported revenue of 696 million yuan and a net profit of 88.83 million yuan; for the first quarter of 2025, revenue was 186 million yuan with a net profit of 20.61 million yuan [4]. Group 3: Strategic Rationale - The acquisition aims to complement Lijuz Group's existing product lines in antibiotics and cardiovascular drugs, allowing both companies to share research and development resources as well as sales channels [4]. - The Vietnamese pharmaceutical market is growing at an annual rate exceeding 10%, and IMP holds EU GMP certification, which could provide Lijuz Group with a gateway to Southeast Asian and European markets [4]. - Lijuz Group's revenue in 2024 decreased by 4.97% year-on-year, primarily due to price reductions from centralized procurement and a decline in demand for antiviral drugs, necessitating the search for new growth opportunities [4].

Core Viewpoint - Lijun Group is accelerating its overseas market expansion through the acquisition of a majority stake in Imexpharm Corporation (IMP) in Vietnam for approximately 1.587 billion RMB, which is expected to enhance its international presence and product synergy [1][2][3] Group 1: Acquisition Details - Lijun Group's wholly-owned subsidiary, LIAN SGP, plans to acquire 64.81% of IMP for about 57.3 trillion VND, equivalent to approximately 1.587 billion RMB, representing 11.45% of the company's latest audited net assets [2] - The acquisition does not constitute a related party transaction or a major asset restructuring, and upon completion, IMP will be included in Lijun Group's consolidated financial statements [2] - IMP, established in 1977, is a leading pharmaceutical company in Vietnam, focusing on the research, production, and sales of pharmaceuticals, including antibiotics and cardiovascular drugs [2] Group 2: Financial Performance - Lijun Group has shown consistent growth in overseas revenue, with figures of 1.565 billion RMB, 1.571 billion RMB, and 1.724 billion RMB from 2022 to 2024, reflecting year-on-year growth rates of 1.72%, 0.4%, and 9.69% respectively [3] - The overseas gross profit margin reached 48.9% in 2024, marking a ten-year high [3] - The company's net profit has been on a positive growth trajectory since 2019, with a net profit of 637 million RMB in Q1 2025, representing a year-on-year increase of 4.75% [1][5] Group 3: Research and Development - Lijun Group has invested over 1 billion RMB annually in R&D since 2021, with total R&D expenditures amounting to 4.941 billion RMB from 2021 to 2024 [5] - As of the 2024 annual report, the company has 45 projects under development, including 23 innovative drugs and high-barrier complex formulations, with 7 projects in the review stage for market approval [5] Group 4: Shareholder Returns - Lijun Group has a strong track record of returning value to shareholders, having distributed cash dividends 25 times, totaling 10.54 billion RMB, with a dividend payout ratio of 47.75% [5]

Market Overview - As of 13:59 today, the Shanghai Composite Index is at 3372.33 points, with a slight decline of -0.23% [1] - The total trading volume of A-shares today is 838.849 billion yuan [1] Stocks Breaking Annual Line - A total of 68 A-shares have surpassed their annual line today, with notable stocks including: - Puris (乖离率 6.48%) - Aisen Co., Ltd. (乖离率 5.81%) - Fosa Technology (乖离率 4.02%) [1] Stocks with Significant Deviation - The stocks with the largest deviation from the annual line include: - Puris: Today's price increased by 7.19% to 30.70 yuan - Aisen Co., Ltd.: Today's price increased by 7.47% to 42.00 yuan - Fosa Technology: Today's price increased by 4.30% to 32.71 yuan [1] Additional Stocks with Positive Performance - Other stocks showing positive performance and their respective deviations include: - Yao Stone Technology: 3.77% increase, 3.51% deviation - Fuling Power: 6.24% increase, 3.42% deviation - Yingjie Electric: 5.37% increase, 3.38% deviation [1] Summary of Stocks with Minor Deviations - Stocks with minor deviations from the annual line include: - Huayang Intelligent: 4.58% increase, 2.48% deviation - Boying Special Welding: 2.32% increase, 2.06% deviation - Stone Technology: 2.02% increase, 1.96% deviation [1]

市场表现： 2025 年5 月22 日，医药板块涨跌幅-0.73%，跑输沪深300 指数0.67pct，涨跌幅居申万31 个子行业第14 名。各医药子行业中，医疗研发外包(+0.04%)、血液制品(-0.37%)、其他生物制品（-0.51%）表现居 前，医院（-1.83%)、线下药店(-1.65%)、医药流通（-1.37%)表现居后。个股方面，日涨幅榜前3 位分别 为三生国健(+20.00%)、亚虹医药(+12.26%)、迈威生物(+11.71%)；跌幅榜前3 位为赛升药业 （-11.63%）、拓新药业(-10.93%)、拱东医疗（-9.99%)。 行业要闻： 近日，Ionis 宣布，公司开发的反义寡核苷酸（ASO）疗法Tryngolza（Olezarsen）在Essence 临床3 期研 究中取得积极的顶线结果。数据显示，该药在治疗6 个月后显著降低了患者的甘油三酯水平，达到主要 终点，且在所有关键次要终点上也取得统计学显著改善。Olezarsen 是一种反义寡核苷酸疗法，旨在抑 制机体产生载脂蛋白C-III（apoC-III，一种在肝脏中产生的调节血液中TG 代谢的蛋白）。 风险提示：新药研发及上市不及预 ...