Performance Forecast - The company expects a net loss attributable to shareholders of between 120 million and 160 million yuan, compared to a loss of 200.31 million yuan in the same period last year [1] - The net loss after deducting non-recurring gains and losses is estimated to be between 140 million and 170 million yuan, compared to a loss of 153.07 million yuan in the previous year [1] - The basic earnings per share are projected to be a loss of between 0.0925 yuan and 0.1233 yuan, compared to a loss of 0.1544 yuan per share last year [1] Reasons for Performance Change - The decrease in loss is attributed to cost reduction and efficiency improvement measures implemented by the company, along with a reduction in market development expenses due to the implementation of industry policies [1] - The company reported an increase in investment income from trading financial assets compared to the previous year, which contributed to the performance improvement [2]

[Hainan Haiyao 2025 Semi-Annual Performance Forecast](index=1&type=section&id=%E6%B5%B7%E5%8D%97%E6%B5%B7%E8%8D%AF%E8%82%A1%E4%BB%BD%E6%9C%89%E9%99%90%E5%85%AC%E5%8F%B82025%E5%B9%B4%E5%8D%8A%E5%B9%B4%E5%BA%A6%E4%B8%9A%E7%BB%A9%E9%A2%84%E5%91%8A) [Performance Forecast Overview](index=1&type=section&id=%E4%B8%80%E3%80%81%E6%9C%AC%E6%9C%9F%E4%B8%9A%E7%BB%A9%E9%A2%84%E8%AE%A1%E6%83%85%E5%86%B5) The company anticipates continued losses in the first half of 2025, but with a significant narrowing of the loss compared to the same period last year, with net profit attributable to shareholders expected to be a loss of 120 million to 160 million yuan, compared to a loss of 200.31 million yuan in the prior year period Key Financial Performance Indicators | Item | Current Period (2025 H1) | Prior Year Period (2024 H1) | | :--- | :--- | :--- | | **Net Profit Attributable to Shareholders** | Loss: 120 - 160 million yuan | Loss: 200.31 million yuan | | **Net Profit After Non-Recurring Items** | Loss: 140 - 170 million yuan | Loss: 153.07 million yuan | | **Basic Earnings Per Share** | Loss: 0.0925 - 0.1233 yuan/share | Loss: 0.1544 yuan/share | [Analysis of Performance Changes](index=1&type=section&id=%E4%B8%89%E3%80%81%E4%B8%9A%E7%BB%A9%E5%8F%98%E5%8A%A8%E7%9A%84%E4%B8%BB%E8%A6%81%E5%8E%9F%E5%9B%A0%E8%AF%B4%E6%98%8E) The narrowing of losses this period is primarily due to effective cost reduction and control measures, leading to a significant year-on-year decrease of approximately 60 million yuan in selling expenses, and an increase of approximately 46 million yuan in investment income due to the absence of debt restructuring losses incurred in the prior year period - Selling expenses decreased year-on-year: Current period selling expenses are estimated at approximately **86 million yuan**, a decrease of approximately **60 million yuan** compared to the prior year period, primarily due to the company's cost reduction and control initiatives and industry policy impacts[5](index=5&type=chunk) - Investment income increased year-on-year: Current period investment income is estimated at approximately **-5 million yuan**, an increase of approximately **46 million yuan** compared to the prior year period, mainly because a **39 million yuan** debt restructuring loss recognized in the prior year period did not recur this period[5](index=5&type=chunk) [Other Important Notes](index=1&type=section&id=%E4%BA%8C%E3%80%81%E4%B8%8E%E4%BC%9A%E8%AE%A1%E5%B8%88%E4%BA%8B%E5%8A%A1%E6%89%80%E6%B2%9F%E9%80%9A%E7%9A%84%E6%83%85%E5%86%B5) The company emphasizes that the financial data in this performance forecast is a preliminary estimate by the finance department, unaudited by a certified public accountant, with final accurate financial data to be disclosed in the 2025 semi-annual report, and advises investors to be aware of investment risks - The financial data related to this performance forecast has not been audited by a certified public accountant[4](index=4&type=chunk) - This performance forecast represents preliminary estimates by the company's finance department, with specific financial data subject to the company's 2025 semi-annual report[5](index=5&type=chunk)[6](index=6&type=chunk)

海南海药（000566）公告，2025年1月1日至2025年6月30日，预计归属于上市公司股东的净利润亏损1.2 亿元至1.6亿元，上年同期为亏损2亿元；扣除非经常性损益后的净利润亏损1.4亿元至1.7亿元，上年同 期为亏损1.53亿元；基本每股收益亏损0.0925元/股-0.1233元/股，上年同期为亏损0.1544元/股。公司推 进降本控费、提质增效，销售费用预计约0.86亿元，较上年同期减少约0.6亿元。投资收益预计约-0.05 亿元，较上年同期增加约0.46亿元。 ...

证券代码：000566 证券简称：海南海药 公告编号：2025-048 海南海药股份有限公司 关于子公司注射用头孢唑肟钠通过仿制药质量和疗效一致性评价的 公告 本公司董事会及全体董事保证公告内容的真实、准确和完整，没有虚假记载、 误导性陈述或者重大遗漏。 海南海药股份有限公司（以下简称"公司"）全资子公司海口市制药厂有限 公司近日获得国家药品监督管理局核准签发的化学药品"注射用头孢唑肟钠"的 《药品补充申请批准通知书》。现将相关情况公告如下： 一、药品基本情况 （一）药品名称：注射用头孢唑肟钠 剂型：注射剂 规格：0.5g、1.0g、2.0g 受理号：CYHB2450238、CYHB2450239、CYHB2450240 适应症：敏感菌所致的下呼吸道感染、尿路感染、腹腔感染、盆腔感染、败 血症、皮肤软组织感染、骨和关节感染、肺炎链球菌或流感嗜血杆菌所致脑膜炎 和单纯性淋病。 审批结论：经审查，本品通过仿制药质量和疗效一致性评价。 （二）药品的其他相关情况 头孢唑肟钠是一种第三代广谱半合成头孢菌素类抗生素，具有广泛的抗菌谱 和较低的耐药性，适用于敏感菌所致的下呼吸道感染、尿路感染、腹腔感染、盆 腔感染、败血症、 ...

证券代码：000566 证券简称：海南海药 公告编号：2025-047 海南海药股份有限公司 关于子公司获得利奈唑胺片药品注册批件的公告 受理号：CYHS2302666 适应症：本品用于治疗由特定微生物敏感株引起的下列感染：院内获得性肺 炎，社区获得性肺炎，复杂性皮肤和皮肤软组织感染，非复杂性皮肤和皮肤软组 织感染，万古霉素耐药的屎肠球菌感染，包括伴发的菌血症等。 药品上市许可持有人：海口市制药厂有限公司 本公司董事会及全体董事保证公告内容的真实、准确和完整，没有虚假记载、 误导性陈述或者重大遗漏。 海南海药股份有限公司（以下简称"公司"）全资子公司海口市制药厂有限 公司近日获得国家药品监督管理局核准签发的化学药品"利奈唑胺片"的《药品 注册证书》。现将相关情况公告如下： 一、药品基本情况 （一）药品名称：利奈唑胺片 剂型：片剂 规格：600mg 审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品 符合药品注册的有关要求，批准注册，发给药品注册证书。 （二）药品的其他相关情况 利奈唑胺是细菌蛋白质合成抑制剂，可以抑制核糖体 50S 亚基的 mRNA 基因 核苷酸与核糖体的结合，组织细菌形成 7 ...

Core Viewpoint - Hainan Haiyao's subsidiary has received approval for the antibiotic "Linezolid Tablets," which will enhance the company's product line and market competitiveness in the high-end antibiotic sector [1] Company Summary - Hainan Haiyao's wholly-owned subsidiary, Haikou Pharmaceutical Factory, has obtained the drug registration certificate for Linezolid Tablets from the National Medical Products Administration [1] - The approval of Linezolid, a bacterial protein synthesis inhibitor, will allow the company to enter the high-end antibiotic market and strengthen its brand influence in the antibiotic field [1] Industry Summary - Linezolid is indicated for the treatment of hospital-acquired pneumonia and community-acquired pneumonia caused by specific sensitive strains of microorganisms [1] - The unique mechanism of Linezolid, which inhibits the binding of mRNA to the ribosome, allows for the formation of the 70S ribosomal complex, providing a competitive edge in antibiotic treatment [1]

Core Viewpoint - Hainan Haiyao's subsidiary has received approval for the injectable drug Cefoperazone Sodium, which is expected to enhance market competitiveness and positively impact the company's performance [1] Company Summary - Hainan Haiyao's wholly-owned subsidiary, Haikou Pharmaceutical Factory, has been granted a drug supplement approval notice by the National Medical Products Administration for the injectable drug Cefoperazone Sodium [1] - The drug has passed the consistency evaluation of quality and efficacy for generic drugs, which is beneficial for the company's market position [1] Industry Summary - Cefoperazone Sodium is a third-generation broad-spectrum semi-synthetic cephalosporin antibiotic, effective against various infections including lower respiratory tract infections, urinary tract infections, and sepsis [1] - The approval of this drug aligns with the industry's trend towards enhancing the quality and efficacy of generic medications, which is crucial for maintaining competitiveness in the pharmaceutical market [1]

Group 1 - Xinhua Medical's subsidiary has received a Class II medical device registration certificate for its thoracic and abdominal endoscope, enhancing its product offerings in minimally invasive surgery [1] - The successful registration of the thoracic and abdominal endoscope enriches Xinhua Medical's portfolio and creates new market growth opportunities [1] Group 2 - Sino-Pharmaceutical has signed a joint research and licensing agreement with Gero PTE to develop new therapies for age-related diseases, involving potential payments of up to $250 million [2] - The collaboration reflects significant market interest and investment potential in the field of age-related disease treatments, combining Gero's AI-driven technology with Sino-Pharmaceutical's resources [2] Group 3 - Yiling Pharmaceutical's G201-Na capsule, a new chemical drug for controlling ovulation in assisted reproductive technology, has received approval for clinical trials [3] - The approval marks a significant breakthrough in Yiling Pharmaceutical's drug development, targeting a market with substantial potential [3] Group 4 - Hainan Haiyao plans to accept financial support from its controlling shareholder, with a maximum amount of RMB 500 million, to stabilize operations and enhance market confidence [4] - The financial assistance, with an annual interest rate of 5%, will be used for the company's main business and to supplement working capital [4]

海南海药股份股份有限公司 独立董事提名人声明与承诺 提名人海南海药股份有限公司董事会现就提名邵蓉 为海南海药股份有限公司第十一届董事会独立董事候选 人发表公开声明。被提名人已书面同意作为海南海药股 份有限公司第十一届董事会独立董事候选人（参见该独 立董事候选人声明）。本次提名是在充分了解被提名人 职业、学历、职称、详细的工作经历、全部兼职、有无 重大失信等不良记录等情况后作出的，本提名人认为被 提名人符合相关法律、行政法规、部门规章、规范性文 件和深圳证券交易所业务规则对独立董事候选人任职资 格及独立性的要求，具体声明并承诺如下事项： 一、被提名人已经通过海南海药股份有限公司第十 一届董事会提名委员会或者独立董事专门会议资格审查， 提名人与被提名人不存在利害关系或者其他可能影响独 立履职情形的密切关系。 ? 是 □ 否 二、被提名人不存在《中华人民共和国公司法》第 一百七十八条等规定不得担任公司董事的情形。 ? 是 □ 否 如否，请详细说明： 三、被提名人符合中国证监会《上市公司独立董事 管理办法》和深圳证券交易所业务规则规定的独立董事 任职资格和条件。 ? 是 □ 否 如否，请详细说明： 四、被提名人符合公 ...

Overview - Hainan Haiyao Co., Ltd. has approved a financial assistance agreement with its controlling shareholder, Xinxing Jihua Pharmaceutical Holdings Co., Ltd., for a maximum amount of RMB 500 million, with a borrowing period of three years [1][2]. Financial Assistance Details - The financial assistance will primarily be used for Hainan Haiyao's main business and to supplement working capital [1]. - The annual interest rate for the financial assistance is set at 5% [4]. Related Party Transaction - The transaction constitutes a related party transaction and does not qualify as a major asset restructuring under relevant regulations [2]. - The independent directors have reviewed and approved the transaction, confirming it does not harm the interests of the company or its shareholders, particularly minority shareholders [5]. Company and Shareholder Information - Xinxing Jihua Pharmaceutical Holdings Co., Ltd. was established on March 13, 2018, with a registered capital of RMB 1.5 billion and total assets of RMB 7.655 billion as of April 30, 2025 [2][3]. - The company has already engaged in various related party transactions amounting to RMB 1.35 billion since the beginning of the year [5]. Impact on Company - The financial assistance is expected to optimize the company's debt structure and enhance liquidity, contributing to stable business operations without significant adverse effects on financial status or operational results [4][5].