公司于2025年4月25日召开第九届董事会第十三次会议审议通过了《关于增 加回购股份资金来源的议案》，同意将本次回购股份的资金来源由"自有资金" 调整为"自有资金及金融机构借款"。除增加回购股份资金来源以外，公司本次 回购股份方案的其他内容未发生变化。具体内容详见公司于2025年4月26日在《证 券时报》和巨潮资讯网（http://www.cninfo.com.cn）上披露的《第九届董事会 第十三次会议决议公告》（公告编号：2025-26）、《关于增加回购股份资金来 源的公告》（公告编号：2025-27）。 根据《公司回购股份报告书》（公告编号：2025-06），若公司在本次回购 期限内发生派发红利、送红股、资本公积金转增股本等除权除息事项，自股价除 权除息之日起，按照中国证监会及深圳证券交易所的相关规定相应调整回购价格 上限。公司2024年度分红派息实施后，回购股份的价格上限由22元/股（含）调 整为21.65元/股（含），调整后的回购股份价格上限自2025年5月22日（除权除 息日）起生效。 证券代码：000739 证券简称：普洛药业 公告编号：2025-37 普洛药业股份有限公司 关于回购公司股份的进展 ...

Group 1 - Taotao Automotive expects a net profit of 310 million to 360 million yuan for the first half of 2025, representing a year-on-year increase of 70.34% to 97.81% [1] - The company specializes in the research, production, and sales of all-terrain vehicles, electric golf carts, electric scooters, electric balance bikes, electric bicycles, and their accessories [1] - China Communications Construction Company plans to repurchase shares worth between 500 million to 1 billion yuan, with a maximum repurchase price of 13.58 yuan per share [1][2] Group 2 - Annoqi's subsidiary received a government subsidy of 1.65 million yuan, accounting for 34.77% of the company's latest audited net profit [2] - Annoqi focuses on the research, production, and sales of mid-to-high-end differentiated dyes [3] - Minfeng Special Paper announced the complete shutdown of its Nanhu plant, as its Haiyan plant is now capable of handling the production capacity [4] Group 3 - Aoto Electronics received a trademark registration certificate from Saudi Arabia, covering various electronic products [5] - Landi Group plans to acquire up to 20.1667% of the shares of Jujia Technology for a total price not exceeding 121 million yuan [6][7] - Lifan Pharmaceutical's Danpi phenol raw material drug has been approved for market launch, utilizing a new process that enhances efficiency and meets market demand [8] Group 4 - Shanghai Construction received a total of 548 million yuan in government subsidies, which accounts for 22.79% of the company's latest audited net profit [8] - Wanbangde's subsidiary received ethical approval for a key clinical trial of a new drug for Alzheimer's disease [8] - Prolo Pharmaceutical's subsidiary received approval for the market launch of a new raw material drug for liver cancer treatment [9] Group 5 - Chenguang New Materials received a government subsidy of 26 million yuan, representing 62.86% of the company's latest audited net profit [10] - Sanyou Medical's subsidiary received a government subsidy of 331,000 yuan, accounting for 28.86% of the company's latest audited net profit [11] - Weichai Heavy Machinery expects a net profit of 132 million to 151 million yuan for the first half of 2025, reflecting a year-on-year increase of 40% to 60% [12] Group 6 - Guanhao Biological announced the termination of its application for a specific stock issuance [13] - China Film plans to use up to 1.5 billion yuan of idle funds for cash management [14] - Aotai Biological intends to use up to 480 million yuan of idle raised funds for cash management [15] Group 7 - Helin Micro-Nano is planning to issue overseas shares and list on the Hong Kong Stock Exchange [17] - Jinpan Technology's vice president resigned due to personal health reasons [18] - Tongyi Zhong's chairman and general manager plan to reduce their shareholdings in the company [19] Group 8 - Naipu Mining signed an overseas contract worth 18.85 million USD [21] - Zhengye Technology completed an asset sale transaction worth 178 million yuan [23] - Lianxin Equipment won a bid for a project worth 157 million yuan from BOE [24] Group 9 - Smart Control plans to apply for a comprehensive credit line of up to 260 million yuan from banks [25] - Keyuan Pharmaceutical's application for issuing shares to purchase assets has been accepted by the Shenzhen Stock Exchange [27] - Meige Intelligent's H-share listing application materials have been received by the China Securities Regulatory Commission [29] Group 10 - Siwei Tuxin's subsidiary submitted an H-share listing application [32] - Metro Design's application for issuing shares to purchase assets has been accepted by the Shenzhen Stock Exchange [32] - Aeston submitted an application for H-share listing [34] Group 11 - Jiu Ri New Materials' shareholders plan to reduce their holdings by a total of 98,900 shares [34] - Yihua Tong's shareholder plans to reduce their holdings by up to 700,000 shares [35] - Xishanghai plans to distribute a cash dividend of 0.08 yuan per share [36] Group 12 - Zhejiang Natural plans to distribute a cash dividend of 1.97 yuan for every 10 shares [37] - Kouzi Jiao plans to distribute a cash dividend of 1.30 yuan per share [38] - Huitong Group plans to distribute a cash dividend of 0.023 yuan per share [40] Group 13 - Tongyong Co. plans to reduce its holdings by up to 0.31% of the company's shares [41] - China Shenhua plans to distribute a cash dividend of 2.26 yuan for every 10 shares [43] - Huangting International's executive director resigned due to personal reasons [45] Group 14 - Jinkai New Energy plans to distribute a cash dividend of 1 yuan for every 10 shares [46] - Heimu Dan plans to distribute a cash dividend of 0.041 yuan per share [47] - Feiyada plans to acquire all or part of the controlling stake in Chang Kong Gear [48]

证券代码：000739 证券简称：普洛药业 公告编号：2025-35 普洛药业股份有限公司 3、规格：15kg/桶 4、生产企业：浙江普洛康裕制药有限公司 5、通知书编号：2025YS00506 6、审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查， 本品符合药品注册的有关要求，批准注册。 二、药品其他相关情况 关于获得化学原料药上市申请批准通知书的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 近日，普洛药业股份有限公司（以下简称"公司"）控股子公司浙江普洛康 裕制药有限公司收到国家药品监督管理局（以下简称"药监局"）签发的甲苯磺 酸多纳非尼《化学原料药上市申请批准通知书》。现将有关情况公告如下： 一、药品注册批准情况 1、化学原料药名称：甲苯磺酸多纳非尼 2、申请事项：境内生产化学原料药上市申请 甲苯磺酸多纳非尼片（商品名：泽普生/Zepsun）是药监局批准上市的Ⅰ类 创新药，上市许可持有人为公司战略合作伙伴苏州泽璟生物制药股份有限公司 （以下简称"泽璟制药"）；用于治疗既往未接受过全身系统性治疗的不可切除 肝细胞癌，以及进展性、局部晚期 ...

Core Viewpoint - Pro Pharmaceutical (000739) announced that its subsidiary, Zhejiang Pro Kangyu Pharmaceutical Co., Ltd., received the approval notice for the listing application of Tofacitinib Tosylate from the National Medical Products Administration. This innovative Class I drug is intended for the treatment of unresectable hepatocellular carcinoma and refractory differentiated thyroid cancer. The approval is expected to have a positive impact on the company's future operations [1]. Group 1 - The drug Tofacitinib Tosylate is classified as an innovative Class I drug [1]. - The drug is specifically used for treating unresectable hepatocellular carcinoma and refractory differentiated thyroid cancer [1]. - The company has signed a research and production service contract with its partner, Suzhou Zejing Biopharmaceutical Co., Ltd., with the raw material ownership belonging to Zejing [1]. Group 2 - The approval from the National Medical Products Administration is anticipated to positively influence the company's future business operations [1].

证券代码：000739 证券简称：普洛药业 公告编号：2025-36 普洛药业股份有限公司 关于对下属公司担保的进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 一、担保情况概述 1、2025 年 6 月 10 日，普洛药业股份有限公司（以下简称"公司"）与中 国银行股份有限公司东阳支行（以下简称"中国银行"）签订《保证合同》（合 同编号：横店 2025 人保字 095 号），同意为公司全资子公司浙江普洛家园药业 有限公司（以下简称"家园药业"）与中国银行签署的《商业汇票承兑协议》（合 同编号：横店 2025 人承字 095 号）中的 10,000 万元银行承兑汇票提供连带责任 保证，担保期限 6 个月。 6、2025 年 6 月 25 日，公司与中国银行签订《保证合同》（合同编号：横 店 2025 人保字 112 号），同意为公司控股子公司浙江普洛康裕制药有限公司（以 下简称"康裕制药"）与中国银行签署的《商业汇票承兑协议》（合同编号：横 店 2025 人承字 112 号）中的 2,859 万元流动资金借款提供连带责任保证，担保 期限 6 个月。 7 ...

Investment Rating - The report maintains a "Buy" rating for multiple companies in the pharmaceutical sector, including Junshi Bioscience, Hualing Pharmaceutical-B, and others [2]. Core Insights - The report emphasizes the broad market for lipid-lowering treatments, particularly focusing on the competitive landscape of PCSK9-targeted drugs, with approximately 500 million adults in China suffering from dyslipidemia, including 120 million with high cholesterol [3][15]. - The pharmaceutical sector saw a 1.60% increase this week, underperforming the CSI 300 index by 0.35 percentage points, with sub-sectors like medical infrastructure and life sciences performing better than generics and innovative drugs [4][31]. Summary by Sections 1. Industry Perspective and Investment Recommendations - The lipid-lowering market is vast, with intense competition in PCSK9-targeted drugs [15]. - Investment strategies should focus on innovative drugs, particularly in the context of increased liquidity and risk appetite in the market [4][31]. 2. Pharmaceutical Sector Performance - The pharmaceutical sector's performance was mixed, with medical infrastructure and life sciences leading, while generics and innovative drugs lagged [4][37]. - The overall P/E ratio for the pharmaceutical industry is 27.69, with a premium of 35.26% compared to the broader A-share market [37]. 3. Company Dynamics - Notable company announcements include Baiyoutai's licensing agreement for BAT2406 in Latin America and Yifan Pharmaceutical's approval for clinical trials of a growth hormone injection [38][40]. - Companies like WuXi AppTec and Lijun Group have made significant moves, including share buybacks and new product approvals [39][41]. 4. Industry Trends - The report highlights the upcoming patent expirations for major small molecule drugs, which could lead to increased demand for raw materials [5][32]. - The report also notes the expected recovery in overseas demand, which may improve the performance of CXO companies [34]. 5. Research and Development Focus - The report discusses the clinical progress of various PCSK9-targeted therapies, including monoclonal antibodies and gene editing approaches, indicating a strong pipeline in this area [3][23][25]. - The competitive landscape for PCSK9 drugs in China is characterized by pricing and adherence challenges, with several products already on the market [27].

Core Viewpoint - The company has completed the cancellation of repurchased shares, reducing its total share capital from 1,169,323,576 shares to 1,158,443,576 shares, which is expected to enhance earnings per share and improve shareholder returns [1][2][3] Summary by Sections 1. Approval and Implementation of Share Repurchase - The company approved a share repurchase plan on March 27, 2024, allowing for the repurchase of shares at a price not exceeding RMB 20 per share, with a total repurchase fund of at least RMB 153 million [1][2] - The actual repurchase involved 10,880,000 shares, accounting for 0.93% of the total share capital, with a total transaction amount of approximately RMB 153 million [1][2] 2. Cancellation of Repurchased Shares - The cancellation of the repurchased shares was confirmed by the China Securities Depository and Clearing Corporation on June 19, 2025, in compliance with relevant laws and regulations [2][3] - The number of shares canceled was 10,880,000, which represented 0.93% of the total share capital before cancellation [2] 3. Changes in Shareholding Structure - Following the cancellation, the total number of shares decreased to 1,158,443,576, with the structure remaining compliant with listing requirements [2][3] - The proportion of unrestricted circulating shares slightly decreased from 99.9628% to 99.9624% after the cancellation [2] 4. Impact of Share Cancellation - The cancellation is expected to enhance the company's earnings per share and improve returns for shareholders without significantly affecting the company's financial status or future development [3] - The cancellation will not harm the interests of shareholders, particularly minority shareholders, and will not lead to changes in the controlling shareholder or actual controller [3] 5. Follow-up Arrangements - The company will proceed with necessary changes in business registration and articles of association as per legal requirements following the completion of the share cancellation [3]

证券代码：000739 证券简称：普洛药业 公告编号：2025-34 普洛药业股份有限公司 关于回购股份注销完成暨股份变动的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 特别提示： 1、本次注销的回购股份数量为 10,880,000 股，占注销前公司总股本的 0.93%。 本次注销完成后，公司总股本将由 1,169,323,576 股变更为 1,158,443,576 股。 2、经中国证券登记结算有限责任公司深圳分公司审核确认，公司本次回购股份 注销事宜已于 2025 年 6 月 19 日办理完成。 根据《深圳证券交易所上市公司自律监管指引第 9 号——回购股份》等相关规 定，回购股份注销完成后，公司应当及时披露，并及时办理变更登记手续。现将公 司回购股份注销完成暨股份变动的具体情况公告如下： 一、本次回购股份的批准及实施情况 关法律法规和公司回购股份方案的有关要求。 公司于 2025 年 3 月 7 日召开第九届董事会第十一次会议，并于 2025 年 4 月 17 日召开 2024 年年度股东大会，审议通过了《关于注销回购股份并减少注册资本的议 案》 ...

Investment Rating - The report recommends a "Buy" rating for multiple companies in the pharmaceutical sector, including Junshi Biosciences, Hualing Pharmaceutical-B, and others [3]. Core Insights - The pharmaceutical sector has outperformed the market, with a focus on the potential of innovative drugs and the CD73 target in cancer immunotherapy [4][5]. - The report highlights the promising clinical progress of CD73 inhibitors, with several products in various stages of clinical trials [21][25]. Summary by Sections Industry Investment Rating - The report provides a list of recommended companies with "Buy" and "Hold" ratings, indicating strong investment potential in the pharmaceutical sector [3]. Industry Performance - The pharmaceutical sector rose by 1.13%, outperforming the CSI 300 index by 0.25 percentage points, with innovative drugs and vaccines leading the performance [5][32]. Company Dynamics - Companies such as Lepu Medical and Sunshine Nuohua have made significant announcements regarding new product approvals and clinical trial progress, indicating a robust pipeline and growth potential [33][34]. Industry Trends - The report discusses the increasing focus on innovative drugs and the impact of regulatory changes on the pharmaceutical landscape, suggesting a shift towards high-efficiency business models in the industry [31][40].

3、规格：25kg/桶 4、生产企业：浙江普洛家园药业有限公司 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 近日，普洛药业股份有限公司（以下简称"公司"）全资子公司浙江普洛家 园药业有限公司（以下简称"家园药业"）收到国家药品监督管理局（以下简称 "药监局"）签发的琥珀酸地文拉法辛《化学原料药上市申请批准通知书》。现 将有关情况公告如下： 一、药品注册批准情况 1、化学原料药名称：琥珀酸地文拉法辛 2、申请事项：境内生产化学原料药上市申请 证券代码：000739 证券简称：普洛药业 公告编号：2025-33 普洛药业股份有限公司 关于获得化学原料药上市申请批准通知书的公告 5、通知书编号：2025YS00429 6、审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查， 本品符合药品注册的有关要求，批准注册。 二、药品其他相关情况 琥珀酸地文拉法辛是第三代抗抑郁药，其通过抑制 5-羟色胺-去甲肾上腺素 再摄取机制来增加 5-羟色胺和去甲肾上腺素浓度而发挥双重抗抑郁作用。该产 品用于成人抑郁症(MDD)的治疗。 三、对公司的影响 此次公司琥珀酸地文拉 ...