Revenue and Profit - The company's revenue for Q1 2025 was ¥455,018,107.75, representing a 20.55% increase compared to ¥377,460,431.51 in the same period last year[5] - Net profit attributable to shareholders decreased by 27.67% to ¥35,790,750.96 from ¥49,485,359.20 year-on-year[5] - Basic earnings per share fell by 28.00% to ¥0.18, compared to ¥0.25 in the same period last year[5] - Total operating revenue for the current period reached ¥455,018,107.75, an increase of 20.5% compared to ¥377,460,431.51 in the previous period[18] - Net profit for the current period was ¥35,790,750.96, a decrease of 27.7% from ¥49,485,359.20 in the previous period[19] - Earnings per share (EPS) for the current period was ¥0.18, down from ¥0.25 in the previous period[19] Cash Flow and Liquidity - The net cash flow from operating activities surged by 356.06% to ¥252,341,548.08, up from ¥55,330,257.73 in the previous year[5] - Cash inflow from operating activities totaled ¥680,318,835.89, up from ¥464,763,229.08, indicating a year-over-year increase of 46.3%[21] - Cash outflow from operating activities was ¥427,977,287.81, compared to ¥409,432,971.35, reflecting a slight increase of 4.2%[21] - The net increase in cash and cash equivalents was ¥355,283,193.12, contrasting with a decrease of ¥68,173,430.97 in the previous period[22] - The ending balance of cash and cash equivalents stood at ¥645,483,817.56, up from ¥440,098,278.17, reflecting an increase of 46.6%[22] Assets and Liabilities - Total assets at the end of the reporting period were ¥4,914,980,393.45, a slight decrease of 0.41% from ¥4,935,272,666.40 at the end of the previous year[5] - Total liabilities decreased to ¥1,890,748,249.96 from ¥1,947,719,670.04[17] - Total equity attributable to shareholders increased to ¥3,024,232,143.49 from ¥2,987,552,996.36[17] Research and Development - The company's R&D expenses decreased by 37.53% to ¥21,559,149.46 from ¥34,513,051.40 year-on-year, reflecting ongoing adjustments in business layout[8] - Research and development expenses were ¥21,559,149.46, down from ¥34,513,051.40 in the previous period, indicating a focus on cost management[18] Operating Costs and Income - The company experienced a 46.54% rise in operating costs, totaling ¥316,982,758.01, attributed to revenue growth and market competition[8] - Total operating costs amounted to ¥412,531,258.48, up 26.8% from ¥325,204,409.51 in the prior period[18] - The company recorded a 310.18% increase in investment income to ¥4,356,576.46, compared to a loss of ¥2,072,743.28 in the previous year[8] Shareholder Information - The total number of common shareholders at the end of the reporting period is 33,741[10] - The top shareholder, Yang Minmin, holds 20.73% of the shares, amounting to 41,403,319 shares[10] - The company has a total of 0 preferred shareholders with voting rights restored[10] - The company has no changes in the number of preferred shareholders or restricted shares during the reporting period[12] Miscellaneous - The company reported a significant increase in contract liabilities by 74.31% to ¥97,821,118.13, indicating pre-received sales not yet recognized as revenue[8] - The company reported a significant increase in other revenue categories, with a 615.29% rise in miscellaneous income[13] - The company's inventory decreased to ¥780,902,805.72 from ¥840,165,143.36[15] - The total assets at the end of the reporting period are ¥2,713,972,014.09, slightly down from ¥2,716,938,169.24[15] - The company's first quarter report was not audited, as stated in the financial disclosures[23]

| 证券代码：300725 | 证券简称：药石科技 | 公告编号：2025-026 | | --- | --- | --- | | 债券代码：123145 | 债券简称：药石转债 | | 南京药石科技股份有限公司 关于提请股东大会授权董事会以简易程序向 特定对象发行股票的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 南京药石科技股份有限公司（以下简称"公司"或"药石科技"）根据《上 市公司证券发行注册管理办法》《深圳证券交易所上市公司证券发行上市审核规 则》《深圳证券交易所上市公司证券发行与承销业务实施细则》等相关规定，公 司董事会于2025年4月24日召开第四届董事会第四次会议，审议通过了《关于提 请股东大会授权董事会办理以简易程序向特定对象发行股票相关事宜的议案》， 同意董事会提请股东大会授权董事会以简易程序向特定对象发行融资总额不超 过人民币3亿元且不超过最近一年末净资产20%的股票，授权期限为2024年年度股 东大会审议通过之日起至2025年年度股东大会召开之日止。上述事项尚需公司 2024年年度股东大会审议通过。现将具体情况公告如下： 一、 ...

| 证券代码：300725 | 证券简称：药石科技 | 公告编号：2025-010 | | --- | --- | --- | | 债券代码：123145 | 债券简称：药石转债 | | 南京药石科技股份有限公司 关于使用部分暂时闲置募集资金及自有资金进行现金管理的公告 一、 募集资金的基本情况 1、2020 年向特定对象发行股票募集资金情况 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有 虚假记载、误导性陈述或重大遗漏。 重要内容提示： 1、投资种类：拟在不影响募集资金投资项目建设和正常经营的前提下，利 用部分暂时闲置募集资金购买安全性高、流动性好、有保本约定的投资产品；利 用自有资金购买安全性高、流动性好、中低风险理财产品等。 2、投资金额：拟使用不超过人民币4.2亿元的暂时闲置募集资金、不超过9.8 亿元的自有资金，该投资额度在投资期限内可循环使用。 3、风险提示：尽管相关产品风险较低，但金融市场受宏观经济的影响较大， 不排除该项投资受到市场波动的影响，敬请投资者注意投资风险。 南京药石科技股份有限公司（以下简称"公司"或"药石科技"）于2025 年4月22日召开的第四届董事会第三次会议 ...

| 证券代码：300725 | 证券简称：药石科技 | 公告编号：2025-008 | | --- | --- | --- | | 债券代码：123145 | 债券简称：药石转债 | | 南京药石科技股份有限公司 第四届董事会第三次会议决议公告 2、审议通过了《关于使用部分暂时闲置募集资金进行现金管理的议案》 经审核，同意在确保不影响募集资金投资计划正常进行和募集资金安全的情 况下，公司使用不超过人民币 4.2 亿元闲置募集资金进行现金管理，有效期自公 司董事会审议通过之日起 12 个月内，在上述额度和期限内，资金可循环滚动使 用。 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 南京药石科技股份有限公司（以下简称"公司"）第四届董事会第三次会议于 2025年4月22日以书面审议会议文件、传签表决的方式召开。会议通知已于2025 年4月18日通过电子邮件方式送达各位董事。会议由董事长杨民民先生召集主持， 应出席董事人数7人，实际出席董事人数7人。本次会议的召集、召开符合《中华 人民共和国公司法》和《南京药石科技股份有限公司公司章程》等有关规定。 一、 董事会会 ...

华泰联合证券有限责任公司关于 二、募集资金投资项目情况 南京药石科技股份有限公司使用部分暂时闲置募集资金 进行现金管理的核查意见 华泰联合证券有限责任公司（以下简称"华泰联合"、"保荐机构"）作为南 京药石科技股份有限公司（以下简称"药石科技"、"公司"）2020 年度向特定对 象发行股票的保荐机构，根据《证券发行上市保荐业务管理办法》《上市公司监 管指引第 2 号—上市公司募集资金管理和使用的监管要求》《深圳证券交易所上 市公司自律监管指引第 2 号—创业板上市公司规范运作》等有关法律法规规定， 对药石科技使用部分暂时闲置募集资金进行现金管理事项进行了核查，具体如下： 一、募集资金的基本情况 根据《2020年度创业板向特定对象发行股票募集说明书》及2023年募集资金 投资项目变更情况，该项募集资金投资项目及使用计划如下： 单位：万元 | 序号 | 项目名称 | 项目投资总额 | 拟投入募集资金 | | --- | --- | --- | --- | | 1 | 南京研发中心升级改造建设项目 | 45,871.64 | 30,300.00 | | 2 | 药物制剂生产基地建设项目 | 40,376.97 | ...

南京药石科技股份有限公司 第四届监事会第三次会议决议公告 本公司及监事会全体成员保证信息披露的内容真实、准确、完整，没有虚假记载、 误导性陈述或重大遗漏。 | 证券代码：300725 | 证券简称：药石科技 | 公告编号：2025-009 | | --- | --- | --- | | 债券代码：123145 | 债券简称：药石转债 | | （http://www.cninfo.com.cn）披露的相关公告。 南京药石科技股份有限公司（以下简称"公司"）第四届监事会第三次会议 于2025年4月22日以书面审议会议文件、传签表决的方式召开，会议通知已于2025 年4月18日通过电子邮件等方式送达各位监事，通知中包括会议的相关资料。本 次会议应出席监事人数3人，实际出席3人。本次会议由监事会主席张树强先生召 集。 本次会议的召集、召开和表决程序符合《中华人民共和国公司法》等法律法 规和《公司章程》的有关规定，所作决议合法有效。 一、 监事会会议审议情况 会议在保证所有监事充分发表意见的前提下，以投票表决方式通过了以下议 案： 1、审议通过了《关于使用部分闲置自有资金进行现金管理的议案》。 经审核，监事会认为：公司 ...

| 证券代码：300725 | 证券简称：药石科技 公告编号：2025-007 | | --- | --- | | 债券代码：123145 | 债券简称：药石转债 | 南京药石科技股份有限公司 关于可转换公司债券 2025 年付息的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 特别提示： 1、"药石转债"将于 2025 年 4 月 21 日按面值支付第三年利息，每 10 张"药 石转债"（面值 1,000 元）利息为 10.00 元（含税）； 2、债权登记日：2025 年 4 月 18 日（星期五）； 3、除息日：2025 年 4 月 21 日（星期一）； 4、付息日：2025 年 4 月 21 日（星期一）； 5、"药石转债"票面利率：第一年为 0.3%、第二年为 0.5%、第三年为 1.0%、 第四年为 1.5%、第五年为 1.8%、第六年为 2.0%。 6、凡在本次付息的债权登记日 2025 年 4 月 18 日（含）前买入并持有本期 债券的投资者享有本次派发的利息，2025 年 4 月 18 日卖出本期债券的投资者不 享有本次派发的利息； 7、 ...

| 证券代码：300725 | 证券简称：药石科技 | 公告编号：2025-006 | | --- | --- | --- | | 债券代码：123145 | 债券简称：药石转债 | | 南京药石科技股份有限公司 关于 2025 年第一季度可转债转股情况的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 特别提示： 1、"药石转债"（债券代码：123145）转股期为 2022 年 10 月 26 日至 2028 年 4 月 19 日；最新有效的转股价格为 33.89 元/股。 2、2025 年第一季度，共有 347 张"药石转债"完成转股（票面金额共计 34,700.00 元人民币），合计转成 1,012 股"药石科技"股票（股票代码：300725）。 3、截至 2025 年第一季度末，公司剩余可转债为 11,471,888 张，剩余可转债 票面总金额为 1,147,188,800.00 元人民币。 根据《深圳证券交易所创业板股票上市规则》《深圳证券交易所上市公司自 律监管指引第 15 号——可转换公司债券》等有关规定，南京药石科技股份有限 公司（以下简称 ...

Investment Rating - The report assigns an investment rating of "Recommended" for the pharmaceutical and biotechnology industry [3][33]. Core Insights - The "AI + Healthcare/Pharmaceutical" theme continues to gain traction, with short-term momentum expected to persist. The report highlights significant stock performance in the sector, with the pharmaceutical and biotechnology sector (SW) rising by 2.71%, outperforming the CSI 300 index, and all sub-sectors showing positive growth, particularly in medical services [3][4]. - In the U.S., Tempus AI, a representative company in medical AI, saw a weekly increase of approximately 30% and over 160% year-to-date, driving the momentum of the medical AI concept. In China, companies like KingMed Diagnostics and Dian Diagnostics announced collaborations with DeepSeek, indicating a shift towards the commercialization of AI applications in healthcare [4][3]. - The report emphasizes investment opportunities in sub-sectors such as "AI + Medical Imaging," "AI + Diagnostic Services," and "AI + Drug Development," recommending key companies including United Imaging, Mindray, BGI Genomics, and WuXi AppTec [3][4]. Industry Performance Tracking - The pharmaceutical and biotechnology sector (SW) rose by 2.71% in the week of February 10-14, ranking 5th among 31 Shenwan primary industries. The CSI 300 index increased by 1.19% during the same period [5][6]. - All sub-sectors experienced growth, with medical services leading at +6.51%, followed by medical devices at +4.81%, and pharmaceutical commerce at +4.18% [5][6]. - Notable individual stock performances included Dian Diagnostics (+46.29%), Mian Health (+31.58%), and United Imaging (+27.33%) [6]. Industry Dynamics and Key Company Tracking - The National Healthcare Security Administration released a list of key tasks for 2025, focusing on efficient medical insurance processes and direct settlements for collected drugs and consumables [7]. - The retail terminal drug sales scale in China is projected to reach 574 billion yuan in 2024, with a growth rate of 3.7%, indicating a slowdown in growth due to demographic and economic factors [8]. - The report also notes significant collaborations, such as Baiyang Pharmaceutical's agreement with Roche for the exclusive marketing rights of a targeted cancer drug in mainland China [9][11]. Industry Data Tracking - The report tracks various industry metrics, including the basic medical insurance fund income, which reached 28,507.29 billion yuan in 2024, showing a year-on-year growth of 5% [15][16]. - The domestic pharmaceutical manufacturing industry achieved a total revenue of 25,298.50 billion yuan in 2024, with profit totals declining by 1.1% year-on-year [17].

Investment Rating - The report assigns an investment rating of "Recommended" for the pharmaceutical and biotechnology industry [3][33]. Core Insights - The "AI + Healthcare/Pharmaceutical" theme continues to gain traction, with short-term momentum expected to persist. The domestic and international markets are witnessing significant developments in AI applications within healthcare, particularly with companies like Tempus AI showing substantial stock price increases [3][4]. - The report highlights investment opportunities in specific segments such as "AI + Medical Imaging," "AI + Diagnostic Services," and "AI + Drug Development," recommending key companies including United Imaging, Mindray, BGI, and WuXi AppTec [3][4]. Industry Performance Tracking - The pharmaceutical and biotechnology sector (SW) rose by 2.71% last week, outperforming the CSI 300 index, which increased by 1.19%. All sub-sectors within the industry experienced growth, with medical services leading at +6.51% [5][6]. - Notable individual stock performances included Dean Diagnostics (+46.29%) and Meinian Health (+31.58%), while stocks like Betta Pharmaceuticals saw declines of -11.36% [6]. Industry Dynamics and Key Company Tracking - The National Healthcare Security Administration released a list of key tasks for 2025, focusing on efficient medical insurance processes and direct settlements for collected drugs and consumables [7]. - Recent collaborations include Baiyang Pharmaceutical signing a commercialization agreement with Roche for the drug Rituximab, and Sanofi Biologics partnering with Baili Tianheng to explore new treatment potentials in oncology [11][12]. Industry Data Tracking - The retail terminal drug sales in China are projected to reach CNY 574 billion in 2024, with a growth rate of 3.7%, indicating a slowdown compared to previous years [8]. - The medical insurance fund's income for 2024 is reported at CNY 28,507.29 billion, reflecting a year-on-year growth of 5.00% [15][16]. - The domestic pharmaceutical manufacturing industry achieved a total revenue of CNY 25,298.50 billion in 2024, remaining stable compared to the previous year [17].