【SynBioCon】 获 悉， 近日，上海交通大学张江高等研究院、生命科学技术学院 瞿旭东团队 联 合澳大利亚昆士兰大学 Mehdi Mobli团队 、上海交通大学生命科学技术学院 赵一雷团队 及 孔旭东 团队 ，在《Nature Chemistry》发表题为"An enzymatic dual-oxa Diels-Alder reaction constructs the oxygen-bridged tricyclic acetal unit of (-)-anthrabenzoxocinone"的研究 论文，首次揭示了一种新型双氧杂Diels-Alder (HDA)酶的催化机制，该酶负责II型聚酮天然产物 (-)-anthrabenzoxocinone（(-)ABX）中手性三环缩酮氧桥结构单元的形成。 生命科学技术学院博士后闫晓丽与昆士兰大学贾新颖博士为论文共同第一作者，瞿旭东教授、Mehdi Mobli教授以及赵一雷教授为论文共同通讯作者；孔旭东长聘教轨副教授，籍顺佳和张梦洁等同学为 共同作者。 杂Diels-Alder反应（HDA）是构建六元杂环化合物最高效的方法之一，在药物化学、材料科学 及天然 ...

Group 1: Modern Agriculture - The first key highlight is modern agriculture, with a total planting area of 600,000 acres for tea, citrus, and kiwi in Pujiang, which was approved as a national modern agricultural industrial park in 2019 [2] - Pujiang has implemented the "two substitutions" project, replacing chemical fertilizers with organic fertilizers and chemical pest control with green prevention methods, making it the only county in the country with all three regional public brand values in the top 40 [2] - Annual sales revenue from agricultural products exceeds 12 billion yuan, with significant contributions from cold chain logistics, which has an annual turnover of 1 million tons [2] Group 2: Industrial Development - The second key highlight is industrial development, with Pujiang being the only small and medium-sized enterprise cooperation zone in Western China approved by the Ministry of Industry and Information Technology [3] - The contribution rate of the industrial sector to the county's economy is 37%, which is 7 percentage points higher than the provincial average, particularly driven by the biomanufacturing industry, which has maintained double-digit growth for several years [3] - Global market share for products like brassinosteroids, hesperidin, and tea polyphenols exceeds 70% [3] Group 3: Ecological Development - The third key highlight is ecological development, with Pujiang being the first national ecological civilization construction demonstration county in Sichuan [3] - The county has proposed the concept of a "rural ecological business district" and aims to transform ecological value into economic benefits, with its experience recognized as an excellent case nationwide [3] - The logistics port in Pujiang is part of the national western land-sea new passage, with trade import and export volume growing at double-digit rates for three consecutive years, and exports accounting for 94% of the total [3]

Core Viewpoint - The Chengdu-Chongqing Economic Circle is focusing on collaborative investment strategies to enhance industrial synergy and attract high-quality projects, with specific measures outlined for 2025 [1][2]. Group 1: Collaborative Investment Measures - The joint investment focus for 2025 includes five key areas with 15 specific measures aimed at deepening cooperation between Sichuan and Chongqing [1]. - The collaborative investment mechanism will be improved to facilitate project flow, including a shared benefits model to address project limitations due to regional constraints [1]. Group 2: Industry Development Initiatives - Targeted initiatives will be categorized by industry sectors such as electronic information, equipment manufacturing, advanced materials, and modern services to enhance competitiveness [2]. - The focus will also be on attracting key enterprises in emerging industries like aerospace information, biomanufacturing, and intelligent manufacturing to establish a hub for technological innovation [2]. Group 3: Global Investment Promotion - The Chengdu-Chongqing Economic Circle will expand its global investment outreach by hosting international promotional events to attract foreign investment in modern industries [2]. - The initiative aims to enhance the global appeal and influence of the Chengdu-Chongqing Economic Circle by presenting significant projects to overseas markets [2]. Group 4: Strategic Location for Investment - The recent joint investment meeting was held in Mianyang, a regional center, to promote investment opportunities and attract quality enterprises to the Chengdu-Chongqing area [3].

Group 1 - Shenzhen aims to attract international talent by leveraging the Guangdong-Hong Kong-Macao Greater Bay Area to create a technology special zone and establish a talent list tailored to their needs [1] - The city has a total of 26,200 high-level talents and 220,000 returnees from studying abroad, with over 7 million various talents, and ranks first in China's 95 post-90s talent attraction for two consecutive years [1][2] - Shenzhen's R&D investment reached 223.66 billion yuan, with an 18.9% year-on-year growth, maintaining double-digit growth for nine consecutive years, and the R&D intensity is at 6.46% [2] Group 2 - Shenzhen is committed to innovation-driven development, focusing on strategic emerging industries such as artificial intelligence, low-altitude economy, biomanufacturing, quantum technology, and 6G [2] - The city plans to integrate resources from leading enterprises, universities, and government to form innovation alliances, enhancing the international technology innovation center in the Greater Bay Area [2][3] - Future plans include deepening cooperation with Hong Kong's Northern Metropolis to create a collaborative innovation pattern, leveraging national strategic platforms [3]

Group 1 - Hainan has issued opinions to develop new quality productivity, focusing on five directions: agricultural, marine, aerial, green, and digital development [1][4][6] - By 2030, Hainan aims to significantly increase R&D funding intensity and enhance innovation-driven development capabilities, with new quality productivity in the five areas accounting for a larger share of the provincial economy [1][4] Group 2 - The strategy includes optimizing the deep-sea technology innovation ecosystem, accelerating the construction of major platforms like the National Marine Comprehensive Test Field, and promoting Nanshan Port as a key deep-sea research base [1][2][4] - Plans to develop emerging marine industries such as deep-sea oil and gas, marine renewable energy, and marine biological manufacturing are outlined, alongside enhancing traditional marine industries like fisheries and tourism [2][5] Group 3 - The initiative emphasizes building a world-class tourism destination and advancing the international tourism consumption center, with a focus on high-quality tourism products and immersive experiences [3][5] - Strengthening the role of technological innovation is crucial, with a multi-level innovation system and support for technology-driven enterprises being prioritized [3][6] Group 4 - The opinions also highlight the importance of fostering a favorable environment for education and technology talent, enhancing financial support, and improving resource allocation mechanisms [6]

Core Viewpoint - The government of Sichuan province is promoting high-quality county economic development through the concept of "ecological high value," aiming to transform ecological advantages into economic benefits [1][2]. Group 1: Agricultural Development - The first "golden signboard" for Pujiang is modern agriculture, with three main products: tea, citrus, and kiwifruit, covering a contiguous planting area of 600,000 acres. The county has implemented organic fertilizer and green pest control initiatives, leading to significant sales revenue exceeding 12 billion yuan [2]. - "Pujiang kiwifruit" is the first in the country to carry a "carbon label," and "Pujiang papaya" has received an international "green pass" [2]. Group 2: Industrial Development - The second "golden signboard" is industrial development, with Pujiang having the only Sino-German SME cooperation zone in Western China. The industrial contribution to the county's economy is 37%, which is 7 percentage points higher than the provincial average. The biomanufacturing industry has maintained double-digit growth in output value for several consecutive years [2]. Group 3: Ecological Initiatives - The third "golden signboard" is ecology, with Pujiang being the first to propose the "Rural Ecological Business District" concept, creating a new economy focused on green development. This initiative has been recognized as an excellent case among small and medium-sized cities nationwide [2]. Group 4: Rural Ecological Business District - The Rural Ecological Business District serves as a new engine for accelerating the transformation of "ecological high value." It aims to create a multi-functional, inclusive industrial community distinct from traditional CBDs, thereby altering the industrial structure of rural areas [3]. - Over 800 companies in technology and digital sectors have settled in the district, generating total tax revenue exceeding 500 million yuan. The collective income of the local community has increased from 100,000 yuan in 2022 to over 2.8 million yuan in 2024 [3]. - Companies in the district report a positive environment for innovation and productivity, with a blend of rural and modern aesthetics enhancing their operational efficiency [3].

【SynBioCon】 获 悉，2025年4月19-20日，中国（海南）自由贸易试验区、国家全面深化改革开放试验区、国家生态文明试验区的重要城市三亚迎 来了一场盛会——生物经济50人论坛（三亚）。这场由深圳市华谷致远生物科技与产业研究院（下称"华谷研究院"）主办，招商三亚深海科技城开发有 限公司承办的论坛，在崖州湾科技城盛大开幕。 本次论坛以"海洋生物制造：重塑未来产业格局"为主题，不仅汇聚了国内200多位顶尖的"产、学、研、投、用"各界领导和专家，更搭建了为产业创新 发展提供战略思路与实践方案的高端平台。相信必将有力推动我国生物经济再上新台阶。 4月19日下午，论坛的预热会议——生物制造产业联盟第三次理事会率先召开，包括理事长单位、副理事长单位、理事单位以及特邀嘉宾在内共计50多 位代表参加。 会上重点围绕工信部国家生物制造业创新中心的建设问题展开讨论 ；会议期间还全面总结2024年联盟工作，并就 生物经济的形势、相 关政策、企业关注的重大问题 等进行深入探讨。 论坛的重要议程之一是 华谷研究院正式发布 2024生物制造产业蓝皮书 。这是华谷研究院联合国内相关机构，专门针对生物制造产业编撰的系统性报 告。该 ...

Core Points - Suzhou is striving to become the "preferred city for youth entrepreneurship," actively recruiting outstanding young scientific talents globally [1] - The "Suzhou Young Scientist" program will officially launch in 2025, focusing on supporting talents in strategic emerging industries and cutting-edge technology fields [1] - The first list of "Suzhou Young Scientists" will be announced at the 2024 Suzhou International Science and Technology Innovation Conference, with 10 individuals selected [2] Group 1 - The "Suzhou Young Scientist" program offers a one-time pre-tax financial support of 500,000 yuan to selected individuals, who will be recognized as leading talents in innovation and entrepreneurship in Suzhou [1] - In 2024, Suzhou's industrial output value reached 4.7 trillion yuan, providing a solid industrial foundation for young talents [1] - Suzhou ranks fifth in national talent friendliness and has been recognized as one of the most attractive cities for foreign experts for 13 consecutive years [1] Group 2 - Among the first 10 "Suzhou Young Scientists," five are professors from universities and research institutions, while the other five are founders or co-founders of companies, with an average age of 33 [2] - The program aims to encourage the growth of outstanding young talents within Suzhou and attract top talents from outside the city [2] - In addition to financial support, Suzhou will provide facilities, investment, and other services to facilitate the rapid implementation of research projects [2]

会议背景 在 2025 年全国"两会"的政府工作报告中，李强总理郑重提出："要建立未来产业投入增长机制，培育生物制造、量子科技、具身智能、6G等未来产业"。 生物制造迎来历史性发展新机遇。 落实党中央、国务院的决策部署，在海南省委、省政府的指导下，经协商，海南省工信厅、三亚崖州湾科技城、华谷生物经济研究院决定以"海洋生物制 造：重塑未来产业格局"为主题，在三亚市共同主办"生物经济 50 人论坛"。 本次论坛邀请国内生物经济领域知名专家、产业龙头、投资机构以及政府部门代表出席，共商涉海生物制造产业发展新未来。 会议概况 一、会议时间 2025年4月19日 15:00-17:00 生物制造产业联盟会议（仅限联盟成员） 2025年4月20日 08:30-17:00 生物经济50人论坛(三亚) 二、会议地点 4月19日 生物制造产业联盟会议——富山厅 4月20日 生物经济50人论坛(三亚)——崖州厅 会议议程 END | I IME 4月20日 | | | | | --- | --- | --- | --- | | | 海洋生物制造 重塑未来产业格局生物经济50人论坛(三亚) | | | | 时间 | 日程安排 | ...

近日，依科赛生物COO陈刚受邀参加媒体访谈，向媒体讲述了依科赛胎牛血清如何从"南美鼻祖"成 为"南美霸主"的艰辛历程，充分展示了企业的家国情怀和社会责任感。 问：南美胎牛血清进入中国市场的早期，面临澳洲产品的主导地位。依科赛为何选择深耕南美血清？在 当时的市场环境下，公司如何突破供应链与技术壁垒，成为"第一个吃螃蟹的人"？ 答：在21世纪初，中国生物医药产业方兴未艾，科研与制药领域对高品质胎牛血清需求激增，但国内市 场以澳洲血源为主，价格较高，供应不稳定。科学家经常面临"揭不开锅"的窘境，严重制约了中国生命 科学产业的发展。 答：主要由三个方面： 1、产品性能优越，屡获殊荣 依科赛生物（ExCell Bio）血清工厂遵循GMP体系，从血源的把控、生产加工、产品制成、成品检测到 成品入库、冷链运输以及售后质量的跟踪解决等全过程，建立了完善的质量控制和管理链，各类型手续 和资质齐全，每个批次的产品均会进行50多项的质量控制检测，不仅涉及全面的理化、微生物检测，也 会进行特定的细胞生长以及病毒检测，保证每一瓶血清的卓越品质和可溯源性。 到目前，依科赛胎牛血清已成为国内同类产品线中占有最大市场份额的品牌，已经初步实现 ...