Core Insights - The 28th Beijing-Hong Kong Cooperation Conference serves as a platform for the Huairou District delegation to showcase its "hard technology" capabilities and explore collaboration opportunities with Hong Kong's international advantages [1] Group 1: Collaboration Opportunities - The Huairou District delegation visited Hong Kong Cyberport, which hosts over 400 tech companies, including 10 newly listed firms this year, highlighting the potential for collaboration in the tech sector [3] - A significant opportunity was identified between Hong Kong Cyberport's AI supercomputing center and Huairou Science City’s large scientific facilities, indicating a natural complementarity in their capabilities [3] - Discussions included specific areas for collaboration such as joint research in key technologies and talent exchange programs [3] Group 2: Academic Partnerships - The delegation's visit to the Hong Kong University of Science and Technology (HKUST) revealed potential for collaboration in semiconductor and sensor research, leveraging Huairou's major national research facilities [4] - Initial cooperation discussions focused on research talent exchange and the use of large scientific instruments, aiming to establish a regular communication mechanism for future joint research [4] Group 3: Financial Support for Innovation - The delegation engaged with Far East Horizon, a comprehensive group spanning finance and industry, to explore solutions for financing challenges faced by tech startups in Huairou [4] - Far East Horizon's vice president indicated plans to discuss the establishment of a tech investment fund to support Huairou's industrial development in high-end instruments [4] - The essence of the exchange was captured in the statement that cooperation between Huairou and Hong Kong is not a "multiple-choice question," but rather an "addition question," emphasizing the mutual benefits of collaboration [4]

"十四五"是我国科技事业发展历程中具有里程碑意义的五年。这五年，科技创新能力稳步提升，科技强国根基不断夯实。我国在科技领域的投入也持续增 加，一起了解大科学装置的三大硬核本领。 0:00 硬核本领一： 从0到1挑战根本性科学问题 中国科学院自然科学史研究所研究员 陈朴：大科学装置不但关系着我们国家的未来的科技竞争力，它同时也可以像毛细血管一样渗透到我们人类生活的方 方面面。可以让我们未来的生活更方便、更便捷、更安全。所以投资大科学装置不单是投资我们国家的未来，也是投资人民和人类的福祉，关系着人类可持 续发展的未来。 硬核本领二： 创新策源 催生颠覆性技术突破 大科学装置是原始创新的策源地，能够催生颠覆性和变革性技术。例如，利用散裂中子源可以研究材料的内部应力，为航空航天、高铁等高端制造提供关键 数据。利用大科学装置平台，还能将新材料的研发周期和成本"减半"，为我国在芯片、新能源等关键领域实现突破提供强大工具，解决国家面临的"卡脖 子"技术难题。 硬核本领三： 关切民生 保障人民生命健康 大科学装置看似高大上，但其实与我们的日常生活和人民的生命健康息息相关。借助大科学装置解析蛋白质结构，可以更快地设计出针对癌症 ...

Core Viewpoint - The "14th Five-Year Plan" marks a milestone in China's technological development, emphasizing the importance of large scientific facilities in driving innovation and addressing fundamental scientific challenges [1][5]. Group 1: Investment in Scientific Infrastructure - Large scientific facilities are crucial for national innovation, requiring significant investment and long-term commitment [3]. - China's R&D investment is projected to exceed 3.6 trillion yuan in 2024, reflecting a steady increase in technological innovation capabilities [5]. Group 2: Core Competencies of Large Scientific Facilities - **Competency 1: Addressing Fundamental Scientific Questions** Large scientific facilities represent the pinnacle of engineering technology, essential for exploring unknowns and tackling fundamental scientific issues, such as those addressed by the Tianyan and Jiangmen neutrino experiments [7]. - **Competency 2: Catalyzing Disruptive Technological Breakthroughs** These facilities serve as sources of original innovation, enabling significant advancements in materials science and reducing the development cycle and costs of new materials, particularly in critical areas like semiconductors and renewable energy [8][9]. - **Competency 3: Enhancing Public Health** Large scientific facilities are directly linked to public health, facilitating the development of targeted therapies for diseases like cancer and Alzheimer's through advanced techniques such as protein structure analysis and proton therapy [11][13]. Group 3: Broader Implications - Investment in large scientific facilities not only enhances national technological competitiveness but also contributes to the well-being and sustainable development of humanity, making it a vital area for future investment [13].

Group 1 - The China Academy of Sciences Shenyang Instrument Co., Ltd. (referred to as Zhongke Instrument) has completed the counseling report for its public offering of stocks and listing on the Beijing Stock Exchange, as disclosed by the China Securities Regulatory Commission [1] - Zhongke Instrument has established a governance structure, accounting foundation, and internal control system necessary for becoming a listed company, and its key personnel are well-versed in the legal responsibilities and obligations related to the issuance and operation in the securities market [1] - The company's IPO journey has undergone several adjustments, initially applying for the Sci-Tech Innovation Board in December 2020, withdrawing the application in May 2021, and later restarting its listing plan in January 2023, ultimately deciding to change its application to the Beijing Stock Exchange by April 2025 [1] Group 2 - Zhongke Instrument primarily engages in the research, production, and sales of dry vacuum pumps and vacuum instruments, which are essential for creating a clean vacuum environment in semiconductor manufacturing processes [2] - The company's vacuum instrument products are categorized into three main types: large scientific devices, vacuum film instruments, and new material preparation equipment, with services including maintenance and technical support for these products [2] - The technical service business focuses on providing maintenance and support for dry vacuum pumps and vacuum instruments to integrated circuit and photovoltaic product manufacturers, with subsidiaries established in Shanghai and Wuhan for efficient customer service [2] Group 3 - The subsidiaries Shanghai Shangkai Instrument and Wuhan Shangkai Instrument are qualified suppliers for major integrated circuit manufacturers such as TSMC, SMIC, Changjiang Storage, and Dalian Intel, directly handling maintenance and repair orders for dry vacuum pumps [3] - These subsidiaries manage the entire process of receiving customer equipment, performing repairs, replacing parts, and testing before returning the equipment to clients [3]