Core Viewpoint - The article emphasizes that Haizheng Pharmaceutical is undergoing a transformation by focusing on high-margin businesses while improving operational efficiency and profitability through cost control and strategic adjustments [1][26]. Financial Performance - In the first three quarters of 2025, Haizheng Pharmaceutical reported total revenue of 7.923 billion, a slight increase of 0.61% year-on-year, while net profit attributable to shareholders decreased by 10.55% to 461 million [3][4]. - The company's non-recurring net profit reached 491 million, marking a significant year-on-year increase of 41.96% [3][4]. - In Q3 2025, revenue was 2.672 billion, up 1.57% year-on-year, with net profit attributable to shareholders soaring by 102.14% to 162 million [3][4]. Profitability Improvement - The non-recurring net profit of 169 million in Q3 2025 is the highest for the same period in history, indicating a strong improvement in the company's core profitability [4][6]. - The overall gross margin increased from approximately 41% in previous years to 45% in the first three quarters of 2025, a rise of 3.8 percentage points year-on-year [7]. - The R&D expense ratio increased from 2.9% in 2021 to 4.7% in 2025, reflecting a commitment to innovation [8]. Cost Control - Management and financial expense ratios have decreased significantly, with the financial expense ratio dropping from 2.9% in 2021 to 0.8% in 2025, indicating reduced financial pressure [11]. - The company has successfully reduced its interest-bearing debt, with short-term borrowings decreasing from 5.112 billion at the end of 2020 to 2.071 billion by Q3 2025 [12]. Business Focus - Haizheng Pharmaceutical is shifting its focus towards high-margin businesses, particularly in the formulation and animal health sectors, which have seen significant sales growth [15][17]. - The company is gradually reducing its involvement in low-margin pharmaceutical distribution, enhancing the overall profitability of its operations [17]. Innovation and R&D - The company is actively pursuing innovation through a three-pronged approach: self-research, collaboration, and investment in new drug development [21]. - Haizheng's self-developed innovative drug, Haibo Maibu Tablets, has seen a 31% increase in sales in 2024, with estimated terminal sales exceeding 500 million [22][24]. - The company is also exploring opportunities in synthetic biology and health aesthetics, with new products launched in these areas [20][24]. Market Position - Haizheng Pharmaceutical has improved its ranking among Chinese pharmaceutical companies, moving up 13 places to 38th, with strong positions in key therapeutic areas [18]. - The company has established a comprehensive production capability in the active pharmaceutical ingredient sector, exporting to over 80 countries [20].

Core Viewpoint - After parting ways with Pfizer, Zhejiang Hai Zheng Pharmaceutical Co., Ltd. is facing significant challenges in its development, despite recent approval of its fumarate bedaquiline raw material, which brings a glimmer of hope for the company [1] Group 1: Company Background - Hai Zheng Pharmaceutical was founded in 1956 and listed on the A-share market in 2000, operating as a state-controlled comprehensive pharmaceutical group with a diverse portfolio including chemical drugs, biological drugs, and veterinary drugs [2] - The company’s core products include the self-developed first-class new drug Haibo Maibu tablets and other medications for liver bile accumulation treatment [2] Group 2: Partnership with Pfizer - The partnership with Pfizer began in September 2012, forming Hai Zheng Pfizer Pharmaceutical Co., Ltd. with a total investment of $295 million, where Hai Zheng held a 51% stake [2] - Initially, the collaboration was beneficial, with the antibiotic "Tezhixing" becoming a major revenue source, contributing significantly to the company's profits in 2013 and 2014 [2][3] Group 3: Challenges Post-Partnership - In 2015, production issues at Pfizer's overseas factories led to a significant drop in sales, and by 2017, Pfizer completely exited the partnership, leaving Hai Zheng to adjust its strategies without a key growth driver [3] - The company has since faced continuous revenue declines from 2022 to 2024, with a drop of 0.82%, 13.82%, and 5.65% year-on-year, and a further decline of 3.48% in Q1 2025 [4] Group 4: Impact of Market Dynamics - The company’s performance has been adversely affected by centralized procurement policies, leading to a significant reduction in market share and a decrease in revenue from its main products [5][6] - In 2023, the revenue from self-operated pharmaceutical business decreased by 10.41 billion yuan, indicating the impact of competitive pressures in the market [6] Group 5: Innovation and R&D - Hai Zheng's self-developed drug Haibo Maibu tablets has shown promising sales growth, reaching over 4 billion yuan in 2023, with potential peak sales estimated at 19.54 billion yuan if market penetration improves [7] - The company has recently received approval for clinical trials of HS387 tablets targeting advanced ovarian cancer and non-small cell lung cancer, but faces stiff competition in these therapeutic areas [8] - The approval of fumarate bedaquiline raw material is a positive development, but the timeline for mass production and revenue contribution remains uncertain [9] Group 6: R&D Investment Trends - R&D investment has fluctuated, with 4.42 billion yuan in 2022, decreasing to 3.94 billion yuan in 2023, but showing a slight increase to 4.16 billion yuan in 2024 [9][10] - The company is establishing advanced R&D platforms, but the effectiveness and impact of these initiatives on innovation remain unclear [10]