Investment Rating - The investment rating for the pharmaceutical and biotechnology industry is "Positive" and the rating has been maintained [1] Core Insights - The pharmaceutical and biotechnology industry index declined by 3.65% during the reporting period, ranking 21st among 31 primary industries, underperforming the CSI 300 index which fell by 2.73% [4][16] - The valuation of the pharmaceutical and biotechnology industry as of October 17, 2025, is a PE (TTM overall method, excluding negative values) of 30.08x, down from 31.23x in the previous period, indicating a downward trend and below the average [4][21] - Key sub-industries include vaccines (55.76x), hospitals (39.64x), and medical devices (38.84x), with the lowest valuation in pharmaceutical circulation (14.29x) [4][21] - The report highlights significant innovations presented at the 2025 ESMO conference, indicating a shift in global oncology drug development from "single-agent breakthroughs" to "combination therapy strategies" [6][8] - The newly released regulations by the State Council aim to standardize clinical research pathways, promoting innovation while ensuring safety [7][25][26] Industry Overview - The report notes that 26 listed companies in the pharmaceutical and biotechnology sector experienced a net reduction in shareholder holdings amounting to 501 million yuan, while 4 companies increased their holdings by 519 million yuan [4] - The report emphasizes the importance of monitoring third-quarter earnings to validate the fundamentals of companies, particularly those with innovative product launches and significant performance improvements [8] Important Industry News - The approval of the first domestic PDE4 inhibitor by He Mei Pharmaceutical marks a significant milestone in the industry [6][34] - The approval of a new indication for GSK's recombinant shingles vaccine expands its application to adults at increased risk due to immunodeficiency [6][36] - The U.S. Senate passed a revised version of the Biosecurity Act, which continues to impose restrictions on certain Chinese biotechnology companies [6][44] - The collaboration between Bai Li Tian Heng and BMS on the iza-bren project has reached a milestone, triggering a payment of 250 million USD [6][47] - The IPO of Xuan Zhu Biotechnology on the Hong Kong Stock Exchange saw a significant oversubscription and a substantial increase in share price during the dark trading period [6][49]

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担个别及连带责任。 近日，天士力医药集团股份有限公司（以下简称"公司"）收到国家药品监督管理局颁发的关于温经汤颗 粒（以下简称"该药品"）的《药品注册证书》，现将相关情况公告如下： 一、药品的基本情况 生产企业：天士力医药集团股份有限公司 审批结论：根据《中华人民共和国药品管理法》及有关规定，经审查，本品符合药品注册的有关要求， 批准本品上市，发给药品注册证书。 二、药品的相关信息 温经汤颗粒处方来源于宋·陈自明《妇人大全良方》，并已列入国家中医药管理局发布的《古代经典名 方目录（第一批）》，由肉桂、酒当归、川芎、醋莪术、牡丹皮、酒牛膝等9味组成。该药品温经补 虚，化瘀止痛。用于血海虚寒，气血凝滞证。症见妇人月经不调，脐腹作痛，脉沉紧。截至目前，公司 针对该药品累计研发投入为1,071.55万元人民币。 药品名称：温经汤颗粒 剂型：颗粒剂 规格：每袋相当于饮片10g 注册分类：中药3.1类 证书编号：2025S03004 药品批准文号：国药准字C20250013 上市许可持有人：天士力医药集团 ...

Core Points - The company has received the drug registration certificate for "Wenjing Decoction Granules" from the National Medical Products Administration, which allows the product to be marketed [1][2] - The drug is classified as a traditional Chinese medicine and is composed of nine ingredients, aimed at treating menstrual irregularities and related symptoms in women [2] Drug Information - Drug Name: Wenjing Decoction Granules - Dosage Form: Granules - Specification: Each bag is equivalent to 10g of medicinal materials - Registration Category: Traditional Chinese Medicine Class 3.1 - Certificate Number: 2025S03004 - Approval Number: National Drug Standard C20250013 - License Holder: Tianjin Tianshi Pharmaceutical Group Co., Ltd. - Manufacturer: Tianjin Tianshi Pharmaceutical Group Co., Ltd. - R&D Investment: The total R&D investment for this drug has reached 10.72 million RMB [1][2] Market Context - The company is one of three manufacturers in China that have obtained the drug registration certificate for Wenjing Decoction Granules [2]

Core Viewpoint - Recently, the company received a drug registration certificate for Wengjing Decoction Granules from the National Medical Products Administration [2] Group 1 - The company is Tianjin Tasly Pharmaceutical Group Co., Ltd. [2] - The announcement was made on the evening of October 13 [2] - The drug registration certificate is a significant regulatory milestone for the company [2]

Core Viewpoint - Tianshili (600535) has received a drug registration certificate from the National Medical Products Administration for its product, Wengjing Decoction Granules, which is indicated for treating specific gynecological conditions [1] Company Summary - Tianshili announced the receipt of the drug registration certificate on October 13 [1] - The product, Wengjing Decoction Granules, is designed to supplement and warm the body, alleviate pain, and is used for conditions related to blood deficiency and stagnation [1] - The specific symptoms addressed by the product include menstrual irregularities and abdominal pain in women [1]

Group 1 - The core point of the article is that Tian Shi Li has received a drug registration certificate for its product "Wen Jing Tang Granules" from the National Medical Products Administration [1] - Tian Shi Li's revenue composition for the year 2024 is as follows: Traditional Chinese medicine accounts for 70.89%, chemical preparations for 15.38%, pharmaceutical commerce for 10.53%, biological drugs for 2.25%, and chemical raw materials for 0.61% [1] - As of the report, Tian Shi Li's market capitalization stands at 23.8 billion yuan [1]

Core Viewpoint - Tianshili (600535.SH) has received a drug registration certificate from the National Medical Products Administration for its product, Wengjing Decoction Granules, which enhances blood circulation and alleviates pain, particularly for women experiencing menstrual irregularities and abdominal pain [1] Summary by Categories Product Development - The company has invested a total of 10.72 million RMB in the research and development of Wengjing Decoction Granules [1] Market Positioning - The approval of Wengjing Decoction Granules enriches the company's portfolio in traditional Chinese medicine products [1]

Core Viewpoint - The company has received a drug registration certificate from the National Medical Products Administration for its product, Wengjing Decoction Granules, which is derived from a historical prescription and is aimed at treating specific gynecological conditions [1] Group 1: Product Information - Wengjing Decoction Granules is based on a prescription from the Song Dynasty and is included in the first batch of the National Administration of Traditional Chinese Medicine's list of classic ancient formulas [1] - The formulation consists of nine ingredients, including cinnamon, wine-soaked angelica, chuanxiong, vinegar-curcuma, peony root, and wine-soaked achyranthes [1] - The product is indicated for conditions such as menstrual irregularities and abdominal pain due to blood deficiency and stagnation [1] Group 2: Financial Investment - The company has invested a total of 10.7155 million RMB in the research and development of this product to date [1]

Group 1: Monetary Supply and Loan Rates - In April, the broad money supply (M2) reached 325.17 trillion yuan, growing by 8% year-on-year, exceeding market expectations [1] - The weighted average interest rate for new corporate loans in April was approximately 3.2%, down about 50 basis points from the same period last year, marking a historical low [2] - The weighted average interest rate for new personal housing loans was around 3.1%, down about 55 basis points year-on-year, also at a historical low [2] Group 2: Corporate Financial Performance - Tencent Holdings reported Q1 2025 revenue of 180.022 billion yuan, a 13% increase year-on-year, with net profit attributable to shareholders rising by 22% to 61.329 billion yuan [2] - Easytron achieved a net profit of 41.7698 million yuan in Q1 2025, reflecting a year-on-year growth of 34.19% [7] - Goldwind Heavy Industry's subsidiary signed a contract worth approximately 1 billion yuan for an offshore wind power project with a European energy company [8] Group 3: Market Trends and Predictions - The AR/VR market in China is expected to grow at a compound annual growth rate (CAGR) of 41.1% from 2024 to 2029, with total investment projected to exceed 10.5 billion USD by 2029, accounting for 26.5% of the global market [2] - The raw milk production in China is projected to decline to 40.79 million tons in 2024, marking the first decrease since 2018, indicating a potential turning point for milk prices in the second half of the year [3] Group 4: Corporate Actions and Developments - Baidu is planning to expand its autonomous driving service "Luobo Kuaipao" to Switzerland and Turkey, with plans to establish a local entity in Switzerland [3] - CATL has received over 50 billion USD in institutional orders, with a subscription rate exceeding 30 times, potentially becoming the largest IPO globally for the year [3] - Vanke A announced that its largest shareholder, Shenzhen Metro Group, intends to provide a loan of up to 1.552 billion yuan to repay bond principal and interest [6]

Group 1 - Vanke A's largest shareholder, Shenzhen Metro Group, plans to provide a loan of up to 1.55 billion yuan to repay the company's bonds [1] - Yidelong reported a net profit of 41.77 million yuan for Q1 2025, a year-on-year increase of 34.19% [1] - Overseas Chinese Town A achieved a contract sales amount of 1.78 billion yuan in April, a year-on-year increase of 10% [1][2] Group 2 - Dajin Heavy Industry's subsidiary signed a contract worth approximately 1 billion yuan for an offshore wind power project with a European energy company [4] - Liao Port Co. announced the resignation of Chairman Wang Zhixian due to reaching retirement age [4] - China Energy Construction's application for a specific stock issuance has been approved by the Shanghai Stock Exchange [6] Group 3 - Xinhua Insurance reported a 27% year-on-year increase in premium income from January to April, totaling 85.38 billion yuan [11] - 吉祥航空's passenger turnover increased by 6.34% in April, with a seat occupancy rate of 86.16% [13] - New City Holdings reported a contract sales amount of approximately 1.76 billion yuan in April, a year-on-year decrease of 52.46% [28] Group 4 - Three Yuan Bio announced a preliminary ruling of a 3.49% countervailing duty on its products in the U.S. [23] - Shanghai Pharmaceutical's product, Wengjing Decoction Granules, has been approved for production [20] - A strategic cooperation agreement was signed between *ST Dali and Zhuhai Yunzhou Intelligent Technology Co., Ltd. to promote the development of intelligent unmanned equipment [22] Group 5 - The construction of the automotive lightweight forging precision processing project by Sanlian Forging has been completed [25] - The company Tianma Technology reported an output of approximately 1,480.16 tons of eel in April [18][19] - The company Victory Technology plans to invest up to 3 billion yuan for share repurchase [42]