从营收结构来看，国发股份医药制造板块包括"海宝"牌珍珠明目滴眼液、珍珠末、珍珠层粉、"国发"牌 胃肠宁颗粒、金银花合剂，"海马"牌跌打药酒、海蛇药酒等产品，上半年收入为1274万元。 此外，国发股份旗下的北海医药和钦州医药两大公司深耕广西北海市、钦州市、防城港市等北部湾地 区，从事医药流通业务，上半年贡献收入9537万元。截至2025年6月，国发股份合计拥有直营店5家，特 许加盟店8家，加盟店53家。 在司法IVD(体外诊断)、分子医学影像中心业务布局上，国发股份主要通过全资子公司高盛生物、北京 香雅医疗技术有限公司，提供法医DNA检测整体解决方案，以及医学影像中心、医疗器械销售等。 2025年前六个月，该部分业务实现营收4362万元。 不久前，国发股份已经完成多项重要人事调整，完善治理结构。2025年公司任命张小玮担任总裁；聘任 李峰为总裁助理、国发制药厂负责人；选举董秋红担任独立董事。 8月25日晚间，国发股份（600538）发布公告称，公司董事长姜烨已完成增持计划，其通过上海证券交 易所集中竞价交易方式累计增持公司股份480.49万股，累计增持金额为3001.66万元。此前公司宣布董事 吴培诚已完成增持 ...

Company Overview - Beihai Guofa Chuanshan Biological Co., Ltd. is primarily engaged in pharmaceutical manufacturing and distribution, judicial IVD (in vitro diagnostics), and molecular medical imaging centers [3][11] - The company operates under various business models including direct sales, agency sales, and self-owned sales teams [5][6] Financial Performance - For the first half of 2025, the company reported a revenue of approximately 153.73 million yuan, a decrease of 13.02% compared to the same period last year [2] - The total profit for the period was a loss of approximately 4.58 million yuan, improving from a loss of 13.69 million yuan in the previous year [2] - The net profit attributable to shareholders was approximately -5.84 million yuan, compared to -16.11 million yuan in the same period last year [2] Industry Context - The pharmaceutical manufacturing industry in China saw a revenue of 1,227.52 billion yuan in the first half of 2025, a decline of 1.2% year-on-year [12] - The drug distribution industry experienced a significant slowdown, with a growth rate of only 0.6% in 2024, the lowest in 15 years [12] - The IVD market is expected to remain stable, with a projected market size of less than 120 billion yuan in 2024, indicating limited growth potential [13] Business Segments - The pharmaceutical manufacturing segment includes products such as eye drops, granules, and traditional Chinese medicine, with a focus on quality control and compliance with GMP standards [3][11] - The judicial IVD segment, operated by the subsidiary Gaoshen Biological, focuses on DNA testing equipment and services, utilizing a direct sales model primarily targeting public security units [5][6] - The molecular medical imaging center, managed by Beijing Xiangya, collaborates with medical institutions to provide imaging services and sells medical devices [11] Market Trends - The pharmaceutical industry is characterized by cyclical, regional, and seasonal demand patterns, with a relatively stable long-term outlook despite short-term fluctuations [11] - The IVD industry is witnessing a shift towards automation and intelligent detection technologies, driven by advancements in AI and big data [13][14]

Performance Meeting Overview - The company held its 2024 annual performance meeting on June 5, 2025, via an online interactive format at the Shanghai Stock Exchange [1] - Key executives including the Secretary of the Board, CFO, and an independent director participated in the meeting to address investor inquiries [1] Product Registration and Development - As of now, the company has completed re-registration for 29 drug numbers at its Lin'an Pharmaceutical Center, with 11 drug numbers at Huangshan Tianmu and Huangshan Mint also completed [2] - The company is working on small-scale trials and commissioned processing for some re-registered drug numbers to enhance its product diversity [2] Key Product Updates - The company's flagship product, Pearl Eye Drops, is undergoing preparations for GMP compliance checks, but the timeline for resuming normal production and sales remains uncertain [2] - The company has launched White Flower Snake Grass Water in collaboration with East China Grape Brewing Co., achieving sales revenue of 342.32 million yuan in 2024 [2] Health Product Strategy - The company is focused on a dual strategy of "premium traditional Chinese medicine + health products," aiming to expand its health product offerings [3] - New products such as Iron Skin Fengtou tablets, soft capsules, and extracts have been added to the existing product line [3] Collaborations and Market Expansion - The company has established a subsidiary for research and development in traditional Chinese medicine and health products, collaborating with renowned TCM teams [3] - Partnerships with Qingdao University aim to innovate TCM applications in health foods and functional products [3] E-commerce Initiatives - The company launched its flagship store on Tmall in May 2025, facilitating online sales of its Iron Skin Fengtou product line [4] - The company plans to leverage internet channels to enhance product promotion and expand market share [4] Mergers and Acquisitions - The company has adopted a cautious yet open approach to mergers and acquisitions, having acquired 51% stakes in Qingdao Simulation Medical Technology Co., Ltd. and Qingdao Tianmu Mountain Medical Technology Co., Ltd. in 2024 [5] - These acquisitions are expected to improve asset quality and enhance the company's operational capabilities [5]

Core Viewpoint - The company held a performance briefing for the fiscal year 2024 and the first quarter of 2025, discussing its business transformation plans and financial performance [1][2]. Group 1: Meeting Details - The performance briefing took place on May 13, 2025, from 11:00 to 12:00 via the Shanghai Stock Exchange Roadshow Center [1]. - Key attendees included the Chairman, CEO, CFO, and independent directors, who engaged with investors through an interactive online format [1]. Group 2: Business Transformation and Progress - The company is focusing on deepening its industrial layout and enhancing market competitiveness, particularly in the judicial IVD sector, with plans for independent R&D and market penetration of DNA testing products [2]. - In the pharmaceutical distribution sector, the company aims to optimize hospital channel management and expand its chain franchise business [2]. - The pharmaceutical manufacturing segment will enhance operational efficiency through organizational restructuring and brand building, with a focus on core products like eye drops [2]. Group 3: Revenue Structure and Performance - The company reported a total revenue of 78.61 million for Q1 2025, with a net profit of 3.14 million, marking a turnaround from losses [9]. - The revenue contributions from different business segments for 2024 were as follows: - Pharmaceutical distribution: 182 million, down 9.34% year-on-year - Judicial IVD: 119 million, up 1.6% year-on-year - Pharmaceutical manufacturing: 35.45 million, down 20% year-on-year [5][6]. Group 4: Future Growth and Market Strategy - The company plans to continue optimizing its business structure, focusing on high-tech development and core biotechnology [8]. - Future growth will be driven by expanding into the health and judicial IVD sectors, leveraging both internal and external growth strategies [10]. - The company is also addressing potential impacts from the US-China trade war by seeking non-US suppliers and promoting domestic product alternatives [12].