Core Insights - The article narrates the emotional journey of a caregiver, Zhu Maomao, who reflects on her experiences caring for her mother suffering from bipolar disorder and Alzheimer's disease, highlighting the complexities of their relationship and the impact of illness on family dynamics [1][2][4][5][7][19]. Group 1: Caregiver Experience - Zhu Maomao describes her role as a full-time mother and caregiver, emphasizing the challenges faced while raising her daughter, who has autism, alongside her mother's mental health struggles [4][5]. - The narrative reveals the emotional toll of caregiving, including feelings of helplessness and the transformation of the mother-daughter relationship as they navigate illness together [7][19]. - Zhu Maomao's reflections on her mother's decline illustrate the gradual loss of independence and the caregiver's evolving role, leading to a reversal of traditional family roles [19][20]. Group 2: Mother's Illness Journey - The article details the progression of the mother's bipolar disorder and subsequent diagnosis of early-onset Alzheimer's disease, including specific symptoms and changes in behavior over time [10][11][15]. - It highlights the mother's emotional resilience and moments of clarity amidst her illness, showcasing her attempts to maintain a connection with her family, particularly her granddaughter [5][15][25]. - The narrative also discusses the impact of medication on the mother's health and quality of life, including side effects and the challenges of managing her care [14][20]. Group 3: Family Dynamics - The relationship between Zhu Maomao and her mother is characterized by a blend of love, frustration, and a search for understanding, as they both cope with their respective mental health issues [31][32]. - The article touches on the societal perceptions of success and failure, contrasting the mother's life experiences with conventional standards, ultimately recognizing her wisdom and resilience as invaluable [31][32]. - The story concludes with reflections on loss and the complexities of familial love, emphasizing the importance of understanding and appreciating the sacrifices made by caregivers [34][35].

Core Viewpoint - The drug Gantoret Sodium Capsule (brand name: Jiuyi) for Alzheimer's disease has become scarce, leading to widespread concern about the difficulties patients face in obtaining medication [2][4][5] Group 1: Supply Issues - Since 2025, Gantoret Sodium Capsule has faced prescription difficulties in hospitals and supply shortages on online platforms [4][5] - The manufacturer, Green Valley Pharmaceutical Technology, acknowledged the supply issues and is in communication with relevant authorities to address the situation [2][4] - Reports indicate that the drug's market price has increased by approximately 40% in recent months, with some pharmacies listing prices as high as 5000 yuan per box [5][6] Group 2: Market Dynamics - The drug was first approved for conditional listing in November 2019 and officially launched in December 2019, allowing patients to purchase it with a doctor's prescription [4][6] - The initial price of the drug was set at 895 yuan per box, but it was later included in the national medical insurance directory, reducing the price to 296 yuan per box [6][7] - The current monthly cost for patients using Gantoret Sodium is approximately 1184 yuan, significantly lower than the combined cost of traditional treatments [6][7] Group 3: Disease Context - Alzheimer's disease is a major neurodegenerative condition affecting over 55 million people globally, with China having the highest number of patients [8] - The treatment options for Alzheimer's disease are limited, with Gantoret Sodium being one of the few drugs that can improve cognitive function without worsening the condition [8][9] - The drug was conditionally approved due to the urgent need for treatment options, despite some initial concerns regarding long-term safety data [9]