Core Insights - Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that imposes a significant burden on patients, families, and society, necessitating a focus on controlling disease activity while minimizing long-term treatment risks [1][2] Group 1: Disease Characteristics - SLE is characterized by an immune system that mistakenly attacks the body's own tissues and organs, leading to diverse clinical manifestations [2] - Approximately 45% of SLE patients in China experience kidney involvement, and 37% have blood system abnormalities, with these rates being higher than in Western populations [2] - China has the highest number of SLE patients globally, predominantly affecting young women of childbearing age, with an average onset age of around 30 years [2] Group 2: Treatment Landscape - Historically, SLE treatment options were limited, primarily relying on steroids and immunosuppressants, leading to a "drug scarcity" situation for patients [3] - Long-term use of steroids can result in significant side effects, including obesity, osteoporosis, and elevated blood sugar levels, while immunosuppressants may increase infection risks [3] - The treatment strategy for SLE is shifting from "symptom control" to "long-term remission and organ protection," with the concept of "targeted therapy" emerging to maintain low disease activity or clinical remission [3] Group 3: Advances in Treatment - Recent advancements in treatment options, including biological agents, small molecule drugs, and cell therapies, have revolutionized SLE management [3] - Effective management of steroid use is crucial, as maintaining steroid levels without reduction equates to not achieving treatment goals [3] - The evolving treatment landscape aims to balance the reduction of steroid-related side effects with the risk of disease relapse during tapering [3]

首企阳光招采公共服务平台由北京企业联合会、北京市企业家协会主办，平台以公开、公平、公正为核 心原则，立足首都丰富采购资源，聚焦三地优势互补、互利共赢，通过精准拉动津冀生产消费升级、畅 通物流运输脉络，为京津冀高质量协同发展凝聚强劲合力。 新京报贝壳财经讯（记者阎侠）2月10日上午，记者获悉，首企阳光招采公共服务平台在北京正式上 线，来自天津、河北的企业代表与北京市政协委员、北京企业联合会会长张建利共同按下启动按键，见 证这一京津冀首家以采购驱动三地产业深度融合发展的阳光招采平台正式投入运营，此举也成为北京优 化营商环境、擦亮"北京服务"品牌的重要实践，为京津冀协同发展注入全新动力。 作为链接三地产业发展的重要桥梁，首企阳光招采公共服务平台实现了产销对接与物流协同的双重升 级。平台通过推行阳光采购模式，将北京优质采购需求全面向天津、河北优质供应商开放，推动三地产 销精准对接，有效激活区域市场活力；同时依托平台数据互通优势，推动京津冀三地完善物流联动机 制，打通跨区域运输堵点，实现物流资源共享，保障采购物资高效流通，助力区域物流运输体系协同优 化。 在打破信息壁垒、推动要素流动方面，平台同样发挥着核心作用。通过京 ...

Core Viewpoint - As the Spring Festival approaches, the choice between "holding stocks or holding cash" has become a focal point for investors, with a consensus emerging among major brokerages favoring "holding stocks" as the better option this year [1][2]. Group 1: Market Sentiment and Predictions - Major brokerages, including Guotai Junan and GF Securities, express optimism about the market's potential for recovery post-holiday, suggesting that the A-share market may experience a favorable "timing, location, and human factors" for an upward trend [2][17]. - Despite a general consensus on holding stocks, several brokerages caution that market performance may still be influenced by multiple risks, including slower-than-expected economic recovery and geopolitical uncertainties [3]. Group 2: Investment Strategies and Sector Focus - Guotai Junan recommends focusing on emerging technology and value sectors, highlighting themes such as commercial aerospace, robotics, urban renewal, and domestic consumption [4]. - Dongwu Securities suggests three main investment directions: overvalued technology sectors, booming industries like energy storage and lithium batteries, and themes related to the 14th Five-Year Plan, including commercial aerospace and 6G technology [5]. - Galaxy Securities advocates for a cautious approach with "light positions," emphasizing the importance of the upcoming "Two Sessions" and the shift towards "new productive forces" in sectors like semiconductors and artificial intelligence [6][7]. - Huaxia Securities emphasizes the importance of preparing for the post-holiday "red envelope" market, noting that technology sectors typically show better elasticity after the holiday [13]. - The investment focus should also include sectors that have underperformed but are expected to recover, such as food and beverage, agriculture, and healthcare [12]. Group 3: Market Dynamics and Historical Trends - Historical data indicates that the market tends to perform better after the Spring Festival, with a common pattern of "lower before the holiday and higher after" across various style indices [11]. - The current market environment is characterized by a high trading volume, with brokerages maintaining a cautious yet optimistic stance, suggesting that the market is not likely to turn bearish easily [8][9]. - The upcoming Spring Festival is seen as a critical period for potential market recovery, with many brokerages encouraging investors to remain confident and prepared for the first wave of the new year's upward cycle [17].

Core Viewpoint - Optoelectronics plans to issue convertible bonds to raise up to 1.38 billion yuan for various projects aimed at enhancing its capabilities in industrial automation and robotics [1] Group 1: Fundraising Purpose - The company intends to use the raised funds for the expansion of industrial 3D vision sensors and smart hardware production [1] - Funds will also support the research and development of AI intelligent vision solution systems [1] - Additional allocations include the industrialization of core components and vision systems for industrial-grade robots, as well as supplementing working capital [1] Group 2: Strategic Goals - The fundraising effort aims to deepen the company's existing advantages in the industrial automation sector [1] - The company seeks to further establish its presence in the core components and vision system solutions for robotics [1]

新京报贝壳财经讯 2月9日，智光电气发布公告称，公司控股子公司智光储能与某公司签订了金额合计 为10.04亿元的《买卖合同》，买方向智光储能购买储能系统。该合同涉及的业务为公司主营业务，若 该合同顺利履行，预计将对公司财务状况以及经营业绩产生积极影响。 ...

模型内测页面提示暂不支持真人人脸。 北京航空航天大学人工智能研究院教授沙磊评价说，现在Seedance 2.0还在小范围内测阶段，字节也限制了一部分模 型功能，比如只有在进行活体认证的情况下可以生成真人视频，不支持输入真人图片或视频做主体参考等，以防止 AI技术被滥用，"这种尝试是企业在技术狂奔时要守住的责任底线"。他表示，AI 的进步从不会因争议停下脚步，而 如何在技术创新与数据合规、版权保护之间找到平衡，让技术突破的红利真正惠及行业与用户，不仅是字节或某家 公司需要持续探索的问题，更是全球 AI 产业共同的命题。 新京报贝壳财经讯（记者罗亦丹）近期，字节跳动最新视频生成模型Seedance 2.0在即梦、豆包、小云雀等产品开启 内测，引发国内国外广泛关注。 新京报贝壳财经记者体验发现，目前在即梦web端、小云雀等平台使用Seedance 2.0，平台会提示暂不支持真人人脸 参考；在即梦App和豆包App，用户需要录制本人形象与声音完成真人校验后才可以制作数字分身，在AI视频中出 镜。 值得注意的是，由于该模型在真实感上的突出表现，引发不少网友对可能混淆现实的担忧。 一名AI创作者介绍，自己第一时间参加了S ...

新京报贝壳财经讯 2月9日，瑞风新能源发布公告称，公司与河北省张家口市宣化经济开发区管理委员 会正式签署投资框架协议，计划总投资约人民币240亿元，在宣化区建设华北地区规模最大的推理算力 集群园区——宣化人工智能算力中心项目。项目主要建设内容为"智算中心+绿电+储能"，分五期工程 建设。一期智算中心拟建设规模不低于3000机架，预计2028年2月前实现一期项目投产运营。 ...

Core Viewpoint - The company plans to acquire 100% of Shanghai Shengpu Fluid Equipment Co., Ltd. through a combination of share issuance and cash payment, with a preliminary valuation of the target company set between 1 billion to 1.2 billion yuan [1] Group 1 - The acquisition will involve 95.97% of the shares being paid for with a 50% cash and 50% share issuance method, while the remaining 4.03% will be acquired entirely in cash [1] - The company's stock has been suspended since January 27 and is set to resume trading on February 10 [1]

新京报贝壳财经讯 2月9日，华润医药在港交所公告称，全资附属公司华润医药投资有限公司已启动潜 在出售华润医药投资及其附属公司所持有合肥天麦生物科技发展有限公司（简称"天麦生物科技"）的约 17.87%股权，其将通过上海联合产权交易所进行公开挂牌，挂牌底价约为14.2亿元。截至公告日期，华 润医药投资及其附属公司持有天麦生物科技少于30%股权。 ...

Core Viewpoint - The recent restructuring actions taken by major state-owned real estate companies in China, including China Overseas Land & Investment, reflect a broader trend of streamlining operations to enhance efficiency and focus on core business areas amid industry challenges [1][2][3][17]. Group 1: Organizational Restructuring - China Overseas Land & Investment has eliminated four regional companies, shifting from a three-tier structure ("headquarters-regional-city") to a two-tier structure ("headquarters-city") [1][4]. - Other companies such as China State Construction Engineering Corporation, Poly Developments, and China Resources Land have also made similar moves to reduce regional layers and consolidate functions, indicating a trend towards "streamlining and focusing" [2][8]. - The elimination of regional companies is seen as a response to the inefficiencies created by additional management layers, which do not align with the current need for cost reduction and efficiency improvement [7][10]. Group 2: Performance Pressures - China Overseas Land & Investment reported a significant decline in sales performance, with a total contracted property sales amount of 251.23 billion yuan in 2025, a year-on-year decrease of 19.1% [9]. - The company also experienced a drop in revenue and net profit, with 2024 revenues at 185.15 billion yuan, down 8.6%, and a net profit of 15.64 billion yuan, down 38.9% [9]. - Similarly, Huafa Group announced its first loss since going public, projecting a net profit loss of between 9 billion to 7 billion yuan for 2025, reflecting a year-on-year decline of over 1000% [11]. Group 3: Strategic Focus and Integration - Companies are not only cutting regional structures but are also integrating business functions to strengthen core competencies. For instance, Poly Developments is restructuring its headquarters into ten functional departments to support its strategic transformation into a "real estate ecological platform" [12][13]. - China State Construction Engineering Corporation's subsidiary, China State Construction Eight Bureau, is reorganizing its operations into three major business segments to concentrate on real estate and enhance competitiveness [15][16]. - The overarching goal of these adjustments is to reduce costs, improve efficiency, and better position companies to navigate the ongoing industry adjustments [17][18].