截至月份: 2025年8月31日 狀態: 新提交 致：香港交易及結算所有限公司 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02359 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 387,076,150 | RMB | | 1 RMB | | 387,076,150 | | 增加 / 減少 (-) | | | 91,150,340 | | | RMB | | 91,150,340 | | 本月底結存 | | | 478,226,490 | RMB | | 1 RMB | | 478,226,490 | | 2. 股份分類 | 普通股 | 股份類別 | A | | 於香港聯交所上市 (註1) | | 否 | | | --- | --- | --- | --- | --- | -- ...

主力资金净流出的行业有23个，非银金融行业主力资金净流出规模居首，全天净流出资金80.79亿元， 其次是计算机行业，净流出资金为70.10亿元，净流出资金较多的还有电力设备、汽车、国防军工等行 业。 医药生物行业今日上涨2.79%，全天主力资金净流入34.75亿元，该行业所属的个股共474只，今日上涨 的有373只，涨停的有14只；下跌的有98只，跌停的有1只。以资金流向数据进行统计，该行业资金净流 入的个股有216只，其中，净流入资金超亿元的有16只，净流入资金居首的是药明康德，今日净流入资 金10.40亿元，紧随其后的是长春高新、恒瑞医药，净流入资金分别为5.99亿元、5.24亿元。医药生物行 业资金净流出个股中，资金净流出超亿元的有7只，净流出资金居前的有博瑞医药、爱尔眼科、美年健 康，净流出资金分别为2.11亿元、1.86亿元、1.82亿元。（数据宝） 医药生物行业资金流入榜 沪指9月1日上涨0.46%，申万所属行业中，今日上涨的有24个，涨幅居前的行业为通信、综合，涨幅分 别为5.22%、4.27%。医药生物行业今日上涨2.79%。跌幅居前的行业为非银金融、银行，跌幅分别为 1.28%、1.03%。 ...

沪指9月1日上涨0.46%，申万所属行业中，今日上涨的有24个，涨幅居前的行业为通信、综合，涨幅分别为5.22%、4.27%。医药生物行业今日上涨2.79%。跌幅居前的行业为非银金融、银行 资金面上看，两市主力资金全天净流出513.00亿元，今日有8个行业主力资金净流入，医药生物行业主力资金净流入规模居首，该行业今日上涨2.79%，全天净流入资金34.75亿元，其次是通信 主力资金净流出的行业有23个，非银金融行业主力资金净流出规模居首，全天净流出资金80.79亿元，其次是计算机行业，净流出资金为70.10亿元，净流出资金较多的还有电力设备、汽车、国 医药生物行业今日上涨2.79%，全天主力资金净流入34.75亿元，该行业所属的个股共474只，今日上涨的有373只，涨停的有14只；下跌的有98只，跌停的有1只。以资金流向数据进行统计， 医药生物行业资金流入榜 医药生物行业资金流出榜 ...

Group 1 - Pharmaceutical stocks in Hong Kong have shown strong performance, with notable gains in companies such as 加科思-B (up 23.18%), 三叶草生物-B (up 22.09%), and others [1] - The overall performance of Hong Kong pharmaceutical companies in the first half of the year has been robust, with 恒瑞医药 achieving record high revenue and profit, and 翰森制药 exceeding revenue expectations [1] - Upcoming major conferences, including the World Lung Cancer Conference (WCLC) and the European Society for Medical Oncology (ESMO), will showcase research results from innovative domestic drugs [1] Group 2 - 海通国际 maintains a positive outlook on Hong Kong pharmaceutical companies due to their stable cash flow, rich R&D pipelines, and normalizing external licensing revenues [2] - The recent slight pullback in the Hong Kong pharmaceutical sector is attributed to rapid fund rotation, with expectations of short-term fluctuations [2] - The long-term value reassessment logic in the pharmaceutical industry remains unchanged, supported by the engineer dividend and a rich catalyst environment in the innovative drug industry [2]

Group 1 - CRO concept stocks have shown significant gains, with WuXi AppTec (603259) up 6.3% at HKD 114.7, WuXi Biologics (02269) up 6.02% at HKD 35.2, and others like Kanglong Chemical (300759) and Kelaiying (002821) also experiencing notable increases [1] - Dongwu Securities reports that 22 CXO listed companies are expected to see revenue, net profit attributable to shareholders, and net profit excluding non-recurring gains and losses grow by 14.16%, 64.03%, and 24.82% year-on-year for the first half of 2025, respectively [1] - The second quarter of 2025 is projected to show further improvement in revenue and profit growth rates, with expected increases of 15.15% in revenue and 53.58% in net profit attributable to shareholders [1] Group 2 - Xiangcai Securities highlights the active performance of the innovative drug industry chain under the backdrop of national encouragement for innovation, despite ongoing pressures from medical insurance cost control [2] - The establishment of a multi-tiered payment system and the rigid demand for medical services are expected to stabilize and rebound the industry [2] - Companies in the pharmaceutical outsourcing services sector, particularly in ADC CDMO and peptide CDMO for weight loss drugs, are recommended for attention, including WuXi AppTec, Haoyuan Pharmaceutical, and WuXi Biologics [2]

Group 1 - The innovative drug sector is experiencing active trading, with companies like Maiwei Bio reaching a 20% limit up and others like Yipin Hong and Zhixiang Jintai seeing over 10% gains [1] - The innovative drug sector has maintained rapid growth in product revenue and external licensing over the past three years, with significant business development (BD) transactions occurring this year [1] - The adjustment of the medical insurance catalog will include commercial insurance for innovative drugs for the first time, indicating a positive trend for the sector [1] Group 2 - According to CICC, domestic engineer dividends, abundant clinical resources, and supportive policies are contributing to the transition of domestic innovative drugs from following to FIC and BIC innovation [1] - The innovative drug industry is entering a 2.0 era, having completed qualitative improvements, with strong pipeline data and ongoing large BD transactions [1] - The upcoming ESMO conference in mid-October is expected to bring new investment opportunities for the sector based on clinical data releases and BD activities [1] Group 3 - Since 2025, policies related to commercial health insurance have been continuously promoted, which is expected to accelerate payment reform in the medical system and support domestic innovation [2] - Recent policies on childcare subsidies are anticipated to alleviate long-term population pressures and stimulate consumption related to infants and young children [2] - With the increase in fiscal policies, domestic medical equipment-related stocks are also gaining market attention [2]

Group 1 - CRO concept stocks have shown significant gains, with WuXi AppTec (02359) up 6.3% to HKD 114.7, WuXi Biologics (02269) up 6.02% to HKD 35.2, and others also experiencing notable increases [1] - Dongwu Securities reports that 22 CXO listed companies are expected to see revenue, net profit attributable to parent, and net profit excluding non-recurring gains and losses grow by 14.16%, 64.03%, and 24.82% year-on-year for the first half of 2025, respectively [1] - The second quarter of 2025 is projected to show further improvement in revenue and profit growth rates, with expected increases of 15.15% in revenue and 53.58% in net profit attributable to parent [1] Group 2 - Xiangcai Securities highlights the active performance of the innovative drug industry chain under the backdrop of national encouragement for innovation, despite ongoing pressures from medical insurance cost control [2] - The establishment of a multi-tiered payment system and the rigid demand for medical services are expected to stabilize and rebound the industry [2] - Companies such as WuXi AppTec, Haoyuan Pharmaceutical, and WuXi Biologics are recommended for attention in the ADC CDMO and peptide CDMO sectors [2]

Core Insights - WuXi AppTec's stock increased by 5.19% to 108.66 CNY per share, with a trading volume of 6.298 billion CNY and a turnover rate of 2.39%, resulting in a total market capitalization of 320.711 billion CNY [1] Company Overview - WuXi AppTec, established on December 1, 2000, and listed on May 8, 2018, is located in Shanghai and Hong Kong. The company provides comprehensive integrated platform services for the discovery, development, and production of small molecule chemical drugs [1] - The revenue composition of WuXi AppTec includes: Chemical business 78.37%, Testing business 12.93%, Biological business 6.02%, Terminated operations 1.90%, Other businesses 0.79% [1] Fund Holdings - According to data, one fund under Guolian An Fund holds a significant position in WuXi AppTec. The Guolian An CSI Pharmaceutical 100A fund (000059) reduced its holdings by 2,800 shares in the second quarter, now holding 35,500 shares, which accounts for 1.04% of the fund's net value, ranking it as the fourth-largest holding [2] - The Guolian An CSI Pharmaceutical 100A fund was established on August 21, 2013, with a latest scale of 178 million CNY. Year-to-date returns are 19.34%, ranking 2403 out of 4222 in its category, while the one-year return is 34.98%, ranking 2704 out of 3779 [2]

Group 1 - The China Securities Hong Kong Stock Connect Medical Theme Index (932069) has risen by 2.99%, with notable increases in constituent stocks such as Chunli Medical (01858) up 10.49%, MicroPort Medical (00853) up 7.02%, and Crystal Technology Holdings (02228) up 6.89% [1] - The Hong Kong Medical ETF (159366) has also seen an increase of 2.44% [1] - The China Securities All Index Medical Device Index (H30217) has increased by 1.46%, with significant gains from Ji Min Health (603222) up 9.98%, Hualan Biological Engineering (301093) up 7.81%, and Huatai Medical (688617) up 6.93% [2][3] Group 2 - The FDA has accepted Vibration-Controlled Transient Elastography (VCTE) as an alternative endpoint for assessing liver fibrosis in patients with Metabolic Associated Steatotic Liver Disease (MASH), marking a significant breakthrough in non-invasive diagnostic technology [4] - This advancement is expected to enhance drug development efficiency for MASH and provide growth opportunities for domestic companies in the non-invasive companion diagnostics field [4] - The pharmaceutical and biotechnology sector showed marginal improvement in Q2 2025, with the innovative drug and CXO sectors performing particularly well, as the CXO industry rebounded with a 14% year-on-year revenue increase and a 54% increase in net profit [4] Group 3 - The domestic medical device industry is gradually recovering from an adjustment period, with market demand showing signs of recovery [5] - In Q2 2025, the medical equipment sector experienced a 5.26% year-on-year revenue growth, and the medical consumables sector maintained stable growth [5] - The Hong Kong Medical ETF (159366) focuses on rare medical segment leaders and has a high CXO content, while the Medical Device ETF (159883) is the largest in A-shares, covering various sub-sectors of the medical device industry [5]

Core Viewpoint - Foreign institutional investors are significantly increasing their holdings in Chinese assets, particularly in H-shares of companies like CATL, ZTE, and WuXi AppTec, indicating a growing confidence in the Chinese market [2][4]. Group 1: Foreign Investment Activities - JPMorgan increased its long position in CATL H-shares from 5.98% to 6.06% and in ZTE H-shares from 6.27% to 6.98% [4]. - Citigroup raised its long position in ZTE H-shares from 6.71% to 7.17% and in WuXi AppTec H-shares from 4.71% to 5.12% [4]. - Morgan Stanley increased its long position in CATL H-shares from 4.96% to 6.05% and in Ganfeng Lithium H-shares from 4.20% to 6.06% [4]. Group 2: Market Performance - The Hang Seng Index recorded a monthly increase of 1.23% in August, marking four consecutive weeks of gains [2][7]. - On August 29, the Hang Seng Index rose by 0.32%, while the Hang Seng Tech Index increased by 0.54% [7]. - Southbound capital saw a significant net purchase of HKD 120.46 billion on August 29, reversing the previous day's net selling trend [7]. Group 3: Sector Insights - The lithium battery industry is experiencing a "de-involution," with a consensus on price discipline emerging, which is expected to improve the competitive landscape [5]. - The solid-state battery industrialization process is accelerating, with several companies planning to achieve mass production by 2026 [5]. - WuXi AppTec's stock surge is driven by favorable policy changes, including the recent announcement of new drug listings by the National Healthcare Security Administration [5]. Group 4: Future Outlook - Analysts expect the Hong Kong market to benefit from improved global liquidity conditions as the Federal Reserve's monetary policy shifts towards a more dovish stance [7][8]. - The ongoing economic stabilization policies in mainland China are anticipated to accelerate the earnings recovery of listed companies, further supporting the Hong Kong market [7]. - The deepening of the Hong Kong listing system reforms is expected to enhance market asset quality and liquidity [7].