Core Insights - JD Health's self-developed medical model "Jingyi Qianxun" is set to undergo a significant upgrade to version 2, following its full open-source release in February this year [1] - The upgraded model utilizes multimodal perception and deep retrieval technology to integrate clinical multi-source information, creating a decision support system that closely resembles real-world scenarios [1] - In the field of specialized disease treatment, "Jingyi Qianxun" 2 demonstrates breakthrough value, particularly in complex scenarios related to malignant tumors and cardiovascular diseases [1] Company Developments - The new version of "Jingyi Qianxun" combines evidence-based medicine with individual patient data to provide personalized treatment recommendations for clinicians [1] - The imaging pathology diagnosis module can quickly analyze imaging and pathological images, significantly reducing the burden on doctors and assisting in treatment decisions [1]

Core Viewpoint - The pharmaceutical e-commerce giants, such as Alibaba Health and JD Health, are experiencing significant growth in their performance, contrasting sharply with the struggles faced by offline pharmacies amid a wave of store closures [1][4]. Group 1: Company Performance - Alibaba Health reported a revenue of 30.598 billion yuan for the fiscal year ending March 31, 2025, representing a year-on-year growth of 13.2%, with a net profit of 1.432 billion yuan, up 62.2% [1]. - JD Health achieved a revenue of 16.645 billion yuan in the first quarter of 2025, marking a year-on-year increase of 25.5%, with an operating profit of 1.071 billion yuan, up 119.8% [2]. - Both companies have achieved profitability for three consecutive years, with JD Health also reporting a net profit of 934 million yuan in the first quarter of 2025, a 4.6% increase year-on-year [3][2]. Group 2: Industry Trends - Offline pharmacies are facing challenges, with five out of eight A-share pharmacy companies reporting a decline in net profit for 2024, and half of the companies continuing to see profit declines in the first quarter of 2025 [4]. - The total number of pharmacies in China decreased by 0.5% at the end of 2024 compared to the third quarter, marking the first quarterly decline in recent years, with a net reduction of 3,395 stores in the fourth quarter [4]. - The shift towards online pharmaceutical retail is accelerating, with the drug sales scale in China's retail market reaching 501.9 billion yuan in 2024, a slight increase of 0.8%, while e-commerce drug sales grew by 4.6% [5]. Group 3: Market Dynamics - Pharmaceutical companies are increasingly focusing on e-commerce channels due to changing patient purchasing habits and the rise of online consultations [6]. - JD Health has solidified its position as a leading platform for the online launch of new specialty drugs, introducing several innovative medications in the first quarter of 2025 [7]. - Alibaba Health continues to leverage its platform for the launch of new drugs, collaborating with well-known pharmaceutical companies to enhance its market presence [7].

Core Viewpoint - The performance of online pharmaceutical giants like Alibaba Health and JD Health continues to grow, contrasting sharply with the struggles faced by offline pharmacies in the current market environment [2][4]. Company Performance - Alibaba Health reported a revenue of 30.598 billion yuan for the fiscal year 2025, marking a year-on-year increase of 13.2%, with a net profit of 1.432 billion yuan, up 62.2% [2][3]. - JD Health achieved a revenue of 16.645 billion yuan in the first quarter of 2025, reflecting a year-on-year growth of 25.5%. The operating profit was 1.071 billion yuan, up 119.8%, and the net profit was 934 million yuan, a 4.6% increase [3]. Industry Trends - Offline pharmacies are experiencing a downturn, with five out of eight listed pharmacy companies reporting a decline in net profit for 2024. In the first quarter of 2025, half of these companies continued to see a drop in net profit [4]. - The total number of pharmacies in China decreased by 0.5% at the end of 2024 compared to the third quarter, marking the first quarterly decline in recent years. In the fourth quarter of 2024, 10,700 new stores opened while 14,100 closed, resulting in a net decrease of 3,395 stores [4]. - The online penetration of pharmaceutical retail is accelerating, with the drug sales scale in China's retail market reaching 501.9 billion yuan in 2024, a slight increase of 0.8%. Online drug sales accounted for 64.5 billion yuan, growing at a rate of 4.6%, surpassing the growth of physical pharmacies [5]. New Product Launches - JD Health has solidified its position as the "first station for online launch of new specialty drugs," introducing several innovative drugs in the first quarter of 2025 [6]. - Alibaba Health continues to leverage its platform for the launch of new drugs, collaborating with well-known pharmaceutical companies to facilitate the introduction of multiple new products [6].

Group 1 - JD Health and BD Medical have launched a new service called "Caring for Bedridden Women's Health: Professional Care Delivered to Home," starting in Beijing [2][3] - The service combines instant retail of medical health products with at-home nursing services, providing a new solution for urinary management for bedridden female patients [2][3] - The target demographic includes women with urinary incontinence, limited mobility, and post-operative patients, addressing complications associated with catheter use [2] Group 2 - PureWick® is an innovative non-invasive urinary management solution designed specifically for bedridden women, improving comfort and dignity while simplifying the workflow for caregivers [3] - Users in Beijing can order PureWick® products through the JD app and receive at-home care services from experienced nurses, ensuring professional care and privacy [3] - This collaboration aims to contribute to the "Healthy China 2030" strategic goals by providing more efficient and user-centered home care solutions [4]

Group 1 - Hong Kong tech stocks showed strength, with JD Health (06618.HK) rising over 4% [1] - JD.com (09618.HK) and Xiaomi Group (01810.HK) both increased by more than 3% [1] - Alibaba (09988.HK) and Baidu (09888.HK) also experienced gains [1]

截至2025年5月20日 09:35，恒生医疗保健指数(HSHCI)强势上涨2.69%，成分股三生制药(01530)上涨33.93%，欧康维视生物-B(01477)上涨7.44%，再鼎医药 (09688)上涨6.39%，石药集团(01093)，诺诚健华(09969)等个股跟涨。恒生医疗ETF(513060)高开高走上涨2.48%，冲击3连涨。最新价报0.50元。流动性方 面，恒生医疗ETF盘中换手2.6%，成交2.66亿元。拉长时间看，截至5月19日，恒生医疗ETF近1月日均成交12.37亿元，居可比基金第一。 湘财证券指出，近期在国家鼓励创新大背景下创新药产业链表现活跃，虽然医药工业复苏仍有待验证，行业受医保控费压力仍在，但多层次的支付体系正在 建立，医疗需求的刚性将共同推动行业企稳回升，建议关注高成长及预期改善两大方向，具体而言：（1）高成长：医药外包服务中的ADCCDMO、减肥药 产业链多肽CDMO等方向公司。（2）预期改善：盈利能力有望触底回升的第三方检验医学实验室，消费医疗中的眼科及口腔等方向的公司。 恒生医疗ETF紧密跟踪恒生医疗保健指数，恒生医疗保健指数提供一项市场参考指标，反映在香港上市、主要 ...

Group 1 - The recent COVID-19 outbreak, highlighted by the diagnosis of singer Eason Chan, has led to a significant increase in demand for antiviral medications and online consultations, with antiviral drug sales on JD.com increasing by 700% year-on-year and 75% month-on-month [1] - JD Health's online hospital has reported a 20% week-on-week increase in COVID-19 related consultations, indicating a rising public concern regarding respiratory infections [1] - JD Health provides 24/7 services for patients, allowing them to access professional medical consultations and medication guidance through the JD app [1] Group 2 - JD.com has ensured a sufficient inventory of respiratory pathogen-related medications, including seven preferred antiviral drugs specifically for COVID-19, such as Molnupiravir and Nirmatrelvir/Ritonavir [2] - To alleviate patient burdens, JD Health has reduced prices on certain antiviral medications, including a 20 yuan decrease on a combination pack of Nirmatrelvir and Ritonavir [2] - JD Health has also launched China's first self-developed influenza-specific drug, Isodax, which has shown to significantly shorten the duration of flu symptoms with a single dose [2] Group 3 - Medical professionals recommend that the public maintain hygiene practices, such as regular handwashing and wearing masks, and seek medical attention promptly if experiencing severe symptoms [3] - Special populations, including the elderly and pregnant women, are advised to monitor their blood oxygen levels to prevent dangerous situations due to hypoxia [3]

Group 1 - The core initiative is the "Home Testing, Love Assistance for the Disabled" public welfare activity launched by JD Health and JD Public Welfare in collaboration with the Beijing Disabled Persons Welfare Foundation, aimed at providing health services to the disabled community in Beijing [1][2] - JD Health, in partnership with three national laboratories, donated home testing services valued at a total of 520,000 yuan, which includes tests for Helicobacter pylori C13, HPV 23 typing, and trace elements such as iodine [1] - The service allows disabled individuals to receive high-quality health testing from home, facilitating a full process of "sample collection delivered to home, professional laboratory testing, and interpretation of reports by top-tier hospitals" [1] Group 2 - The event highlights the social responsibility and compassion of JD Health, JD Public Welfare, and the collaborating laboratories, showcasing how technology and innovation can lower health management barriers for special groups [2] - The initiative is not only a public welfare action but also a call for more social forces to join in supporting the disabled community, aiming to create a better life for them [2] - The event was marked by an 83-year-old hearing-impaired artist presenting a piece of art to express gratitude, symbolizing the emotional connection and appreciation fostered by the initiative [2]

Investment Rating - The stock rating for JD Health International Inc. is Underweight [5] - The industry view is Attractive [5] Core Insights - JD Health International Inc. maintained its 2025 targets despite a strong performance in Q1 2025, aiming for mid-teens revenue growth and flat operating profit [3][8] - The company expects over 20% growth in drug sales, mid-teens growth in nutritional products, and high single-digit growth in medical devices for the full year 2025 [3] - The gross profit margin (GPM) is anticipated to improve due to supply chain management efficiencies and increased advertising income, particularly in nutritional products [3] - JD Health's strategic focus includes enhancing B2C drug sales, especially for originator drugs, which currently represent approximately 30% of total drug sales [4] - The company plans to increase offline investments through greenfield projects rather than large-scale mergers and acquisitions [4] Financial Performance - In Q1 2025, JD Health reported revenue of RMB 16.6 billion, reflecting a year-over-year increase of 25.5%, which was 11% above consensus estimates [8] - The adjusted operating profit grew by 73% year-over-year to RMB 1.31 billion, with an adjusted operating profit margin of 7.9%, up 2.2 percentage points year-over-year [8] - Adjusted net profit rose by 47.7% year-over-year to RMB 1.77 billion, with an adjusted net margin of 10.6% [8]

Group 1 - The Hang Seng Medical Index ETF has shown significant liquidity with a turnover of 1% and a transaction volume of 2.6148 million yuan, with an average daily transaction volume of 27.4616 million yuan over the past month [2] - The ETF's scale has increased by 28.6087 million yuan in the past month, ranking first among comparable funds, with a share increase of 12 million units in the last two weeks, also the highest among peers [2] - In terms of capital inflow, the ETF has seen net inflows on 5 out of the last 8 trading days, totaling 14.5271 million yuan [2] - The current price-to-earnings ratio (PE-TTM) of the Hang Seng Medical Healthcare Index is 23.4, which is in the 4.36% percentile over the past year, indicating a valuation lower than 95.64% of the time in the past year, suggesting historical low valuations [2] - The top ten weighted stocks in the Hang Seng Medical Healthcare Index account for 57.09% of the index, including companies like WuXi Biologics and BeiGene [2] Group 2 - Since the reform of new drug research and development policies in 2015, China's innovative drug industry has developed a strong ecosystem, integrating excellent resources in preclinical and clinical stages, which has gained recognition from multinational corporations (MNCs) [3] - The pharmaceutical and biotechnology sector's Q1 2025 financial reports show stable revenue and profit performance, with notable improvements in certain sub-industries, indicating a return of market enthusiasm for the sector [3] - There is a recommendation to focus on international biotech companies, revaluation of innovative pipelines in generic companies, and companies in the CXO industry with significant order and operational improvements [3] - Investors without stock accounts can access investment opportunities in the Hong Kong medical sector through the Hang Seng Medical Index ETF linked fund (018433) [3]