随着上半年公募基金业绩收官战进入倒计时，医药主题基金以碾压性优势席卷收益榜单。 Wind数据显示，截至6月14日，公募主动权益类基金前十名中竟有9只医药主题产品，汇添富香港优势精选A更 以103.67%的收益率率先撞线"翻倍基"，暂居收益率榜首，2025年半程 悬念花落谁家 ，值得期待。 多位公募业内人士对券商中国记者表示，这场由创新药研发突破、港股流动性复苏、跨境BD交易重构估值体 系等多重动能驱动的医药盛宴，不仅改写了年度基金排名格局，更折射出资本市场对"中国创新"力量的重估与 期待。 医药基金霸屏公募半年业绩榜 随着6月过半，半年度公募主动权益基金的业绩排名即将出炉。年初至今，医药板块延续强势表现，多只医药 主题基金凭借精准布局和行业红利实现业绩爆发，市场无重大变化之下，医药基金将成为半年度收益最大的赢 家。 以汇添富香港优势精选A为例，此前披露的一季报显示，一季度末前十大重仓股分别是荣昌生物、科伦博泰生 物-B、信达生物、和黄医药、康诺亚-B、翰森制药、康方生物、诺诚健华、来凯医药-B、百济神州，创新药概 念股占据绝大多数。 唐晨对记者表示，香港联交所于2018年推出18A上市规则，较科创板更早地为未 ...

| 证券代码：688331 | 证券简称：荣昌生物 | 公告编号：2025-033 | | --- | --- | --- | | 港股代码：09995 | 港股简称：榮昌生物 | | 荣昌生物制药（烟台）股份有限公司 关于公司核心药品专利获得期限补偿的提示性公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重 大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 近日，荣昌生物制药（烟台）有限公司（以下简称"公司"或"荣昌生物"）收到 国家知识产权局下发的《药品专利权期限补偿审批决定》，现将相关情况公告如下： 一、 涉及药品专利基本情况 专利号：ZL200710111162.2 专利名称：优化的 TACI-Fc 融合蛋白 专利申请日：2007 年 6 月 15 日 涉及药品：注射用泰它西普 二、 药品专利权期限补偿审批决定主要内容 按照中国专利法及其实施细则相关规定，决定给予该专利药品专利权期限补偿，补 偿天数 1827 天，原专利权期满终止日 2027 年 6 月 15 日，现专利权期满终止日 2032 年 6 月 15 日。药品专利权期限补偿期间，其保护范围限于国务院药品监 ...

Core Viewpoint - Rongchang Biopharma has received a patent term compensation decision from the National Intellectual Property Administration, extending the patent protection for its drug TACI-Fc fusion protein until June 15, 2032, which enhances its market exclusivity and competitive edge in the Chinese market [1] Summary by Relevant Sections - **Patent Information** - The patent number is ZL200710111162.2, with the application date of June 15, 2007, and the original expiration date of June 15, 2027 [1] - The compensation period granted is 1827 days, extending the patent protection [1] - **Impact on Company Strategy** - The extension aligns with the company's strategic development plan, providing an additional 5 years of market protection for its core product [1] - This extension is expected to significantly enhance the drug's exclusive sales window in the Chinese market, contributing to long-term performance growth and strengthening the company's core competitiveness [1]

Group 1 - The innovative drug sector is experiencing a downturn, with Rongchang Biologics falling over 7% [1] - Other companies such as Rundu Co., Ltd. (002923), Rejing Biologics, Warner Pharmaceuticals, and Wanbang Medicine (301520) also saw declines [1] - There is a disclosure of dark pool fund flows, indicating signals for early detection of stock accumulation by major investors [1]

Group 1 - Shengxiang Biology plans to acquire 10% equity of Hunan Shengweisi Rui Biotechnology Co., Ltd. for 5 million RMB, focusing on sepsis diagnostic products for emergency and critical care [1] - This acquisition is expected to expand Shengxiang's business in the in vitro diagnostic field and enhance its competitiveness in severe infection diagnostics, signaling a proactive approach to seeking new growth points [1] Group 2 - Changfeng Pharmaceutical has submitted an IPO application to the Hong Kong Stock Exchange, with CITIC Securities and CMB International as joint sponsors [2] - Established in 2007, Changfeng focuses on inhalation technology and drugs for respiratory diseases, with its first approved product CF017 for bronchial asthma [2] - The IPO aims to leverage capital markets to expand R&D and production scale, enhancing market competitiveness in the respiratory disease treatment sector [2] Group 3 - BeiGene announced that the FDA approved its "Baiyueze" tablet for all approved indications, based on studies showing bioequivalence with the capsule form [3] - The tablet form is smaller and easier to swallow, which may improve patient compliance and expand market applications [3] - This approval strengthens BeiGene's competitiveness in the global hematologic oncology market and boosts investor confidence in future growth [3] Group 4 - Rongchang Biopharmaceutical's stock surged over 20% following news of international cooperation discussions at the European Renal Association Congress [4] - The company highlighted its research capabilities and international potential, with expectations for product collaboration to maximize commercial value [4] - This reflects the capital market's recognition of the overseas prospects for domestic innovative pharmaceutical companies [4] Group 5 - Hecolin Pharmaceuticals' subsidiary, Nona Bio, entered into a licensing agreement with Visterra, Inc. to utilize its HCAb technology platform for advancing next-generation immunotherapy and autoimmune disease treatments [5][6] - This collaboration showcases the competitive and commercial value of the HCAb technology platform, potentially enhancing Hecolin's influence in the biotherapy field [6] - The partnership is expected to attract investor interest and drive stock price and valuation increases [6]

Market Overview - The A-share market experienced slight fluctuations with the Shanghai Composite Index up by 0.01%, the Shenzhen Component down by 0.11%, and the ChiNext Index up by 0.26% [1] - The total market turnover reached 1,303.5 billion yuan, an increase of 16.9 billion yuan compared to the previous day [1] Innovation Drug Sector Performance - The Guotai Innovation Drug ETF (517110) saw a daily increase of 4.39% [2] Driving Factors for Growth - On June 12, China Biopharmaceutical announced potential landmark licensing deals at the 46th Goldman Sachs Global Healthcare Conference, following similar announcements from other companies [4] - The National Healthcare Security Administration released a draft for the 2024 National Medical Insurance Drug List, indicating a more favorable review process for innovative drugs, which is expected to ease pricing pressure [4] - Local governments, including Shanghai and Beijing, have introduced supportive policies for the biopharmaceutical industry, enhancing confidence in the sector [4] Clinical Progress and Data - The ASCO conference showcased a record 73 studies from Chinese innovative drug companies, with nearly 50% focused on ADC and bispecific antibody fields [5] - Notable clinical results include: - Heng Rui Medicine's PD-1 inhibitor showing a median progression-free survival (mPFS) of 10.2 months, a 35% improvement over existing therapies [5] - BeiGene's BTK inhibitor achieving a total response rate (ORR) of 78% in lymphoma indications [5] - Rongchang Biopharmaceutical's ADC drug receiving FDA breakthrough therapy designation for gastric cancer [5] - Kangfang Biopharmaceutical's bispecific antibody AK112 meeting primary endpoints in Phase III trials [5] Future Outlook - The FDA is expected to make a decision on Innovent Biologics' PD-1 inhibitor for lung cancer on June 15, which could mark a significant milestone for Chinese innovative drugs in the U.S. market [6] - The upcoming ESMO conference is anticipated to reveal more clinical data from Chinese innovative drugs, particularly in high-incidence cancers [6] - The total value of License-out transactions for Chinese innovative drugs has surpassed 50 billion USD, reflecting a 30% increase year-on-year [6] Financial Performance Expectations - Approximately 60% of companies in the CSI Hong Kong-Shenzhen Innovation Drug Index are expected to achieve positive operating cash flow by 2025, driven by the commercialization of key products and improved R&D efficiency [7] Investment Opportunities - The Guotai Innovation Drug ETF (517110) closely tracks the CSI Hong Kong-Shenzhen Innovation Drug Industry Index, capturing beta opportunities in the sector [10]

暗盘资金正涌入这些股票，点击速看>>> 荣昌生物今日涨17.55%，成交额12.09亿元，换手率11.04%，盘后龙虎榜数据显示，沪股通专用席位买 入1.18亿元，三机构专用席位净买入1.44亿元，二机构专用席位净卖出1.93亿元。 ...

Group 1 - The core viewpoint of the news highlights the significant stock performance of Rongchang Biopharmaceuticals, with a notable increase in share price and trading volume, outperforming the Hang Seng Index [1] - As of June 12, the Hang Seng Index fell by 1.36%, while Rongchang Biopharmaceuticals' stock price rose by 20.1%, with a trading volume of 28.84 million shares and a turnover of 1.605 billion HKD [1] - Over the past month, Rongchang Biopharmaceuticals has seen a cumulative increase of 28.17%, and a year-to-date increase of 233.33%, surpassing the Hang Seng Index's growth by 21.47% [1] Group 2 - Financial data shows that as of March 31, 2025, Rongchang Biopharmaceuticals achieved total revenue of 526 million RMB, a year-on-year increase of 59.17%, and a net profit attributable to shareholders of -254 million RMB, with a growth of 27.16% [1] - The gross profit margin stands at 83.26%, and the debt-to-asset ratio is 66.62% [1] - Institutional ratings from Zhongtai International Securities Co., Ltd. give a "Buy" rating with a target price of 51.3 HKD [1] Group 3 - The average price-to-earnings (P/E) ratio for the pharmaceutical and biotechnology industry is 4.2 times, with a median of 6.01 times [1] - Rongchang Biopharmaceuticals has a P/E ratio of -18.33 times, ranking 107th in the industry [1] - Comparatively, other companies in the health sector have P/E ratios such as Dajiang International (0.56), Jingyou Pharmaceutical (0.68), Kingsray Biotechnology (1.6), Dongrui Pharmaceutical (3.08), and Charoen Pokphand International (3.16) [1] Group 4 - Rongchang Biopharmaceuticals was co-founded in 2008 by Wang Weidong and Dr. Fang Jianmin, with its headquarters located in Yantai, Shandong Province, China [2] - The company focuses on discovering, developing, producing, and commercializing innovative biopharmaceuticals targeting major diseases such as autoimmune disorders, tumors, and ophthalmology [2]

Group 1 - The Hong Kong stock market's innovative drug concept saw a strong performance in the afternoon, with Rongchang Biopharmaceutical and China National Pharmaceutical Group rising over 15% [1] - Other companies such as Junshi Biosciences, Zhaoyan New Drug (603127), BeiGene, and Kelun Pharmaceutical (002821) also experienced gains exceeding 5% [1] - Investors can buy Hong Kong stocks through A-share accounts without the need for the Hong Kong Stock Connect, allowing for T+0 trading [1]

Group 1 - Hong Kong biopharmaceutical stocks experienced a significant rise in early trading, with Zai Lab (09688.HK) increasing by over 8.5% [1] - Kelun-Biotech (06990.HK) saw a nearly 6% increase, while BeiGene (06160.HK) rose by over 4% [1] - Other companies such as Rongchang Biologics (09995.HK), WuXi Biologics (02269.HK), Innovent Biologics (09969.HK), and WuXi AppTec (02359.HK) all recorded gains of over 3% [1]