R&D and Innovation - The company plans to complete the reserve of 40-50 drug varieties annually and initiate at least 6 self-developed generic drug projects[2] - The company has established a tiered R&D product sequence to ensure continuous market competitiveness by systematically applying for new drug varieties[2] - The company's R&D system continued to introduce high-level talents in 2022, optimizing the self-developed expert team and advancing the development of generic and innovative drug projects through international collaborations[109] - Completed registration and submission for 11 generic drug projects, with 11 receiving acceptance notices, including the FDA submission for Tofacitinib Citrate Tablets, a dual China-US project[191] - Initiated Phase I clinical trials for the anti-tumor innovative drug ZBD1006, with 5 dose escalation groups completed[191] - Increased R&D expenses by 28.46% to 709.48 million yuan compared to the previous year[200] - The company is actively expanding international cooperation to introduce innovative and generic drug projects that align with its strategic direction[193] - The company is exploring collaborations with multinational pharmaceutical companies, biotech firms, and academic institutions to develop innovative drugs[193] Quality Control and Safety - The company has implemented a dual-constraint system of "physical and chemical indicators + brand indicators" to ensure the quality and stability of raw materials[4] - The company has developed an online monitoring system for the extraction process and a network chromatography instrument detection system to enhance quality control[4] - The company has established a drug safety monitoring and re-evaluation system to ensure the safety of drugs throughout their lifecycle[4] Financial Performance and Dividends - The total remuneration for directors, supervisors, and senior management in the reporting period was 5.7856 million yuan[21] - The company's cash dividend for 2022 is RMB 26,303,308.98, with a dividend payout ratio of 14.19% of the net profit attributable to ordinary shareholders[29] - The total dividend amount, including cash dividends and share repurchases, is RMB 56,294,634.28, accounting for 30.37% of the net profit attributable to ordinary shareholders[29] - The company plans to distribute a cash dividend of 0.28 yuan per 10 shares, totaling 26,303,308.98 yuan[137] - Total cash dividends, including share repurchases, amount to 56,294,634.28 yuan, representing 30.37% of net profit attributable to shareholders[137] Environmental Protection and Compliance - The company's environmental protection investment in 2022 amounted to RMB 1,456.26 million[50] - The company's wastewater and exhaust emissions comply with national standards, with regular third-party testing conducted[36][52][58][59] - The company has established a comprehensive environmental protection management system, including waste management and emergency response plans[55][56] - The company's internal control system is effective, with an unqualified opinion from the audit firm[32][49] Market Performance and Sales - The company's blood stasis injection product saw a price adjustment from "limited to secondary and above medical institutions for stroke paralysis or central retinal vein occlusion patients" to "limited to secondary and above medical institutions"[70] - The company's bone and muscle system disease treatment segment generated revenue of 602.244 million yuan, with a gross profit margin of 75.34%, but revenue decreased by 27.56% year-over-year[71] - The company's traditional Chinese medicine products ranked first in hospital market share, with a year-over-year sales growth of 3.3% in the fourth quarter of 2022[85] - The company's anti-tumor and immunomodulator products ranked second in hospital market share, with a year-over-year sales decline of 1.9% in the fourth quarter of 2022[85] - The company's systemic anti-infective drugs ranked third in hospital market share, with a year-over-year sales decline of 2.1% in the fourth quarter of 2022[85] - The company's digestive and metabolic drugs ranked fourth in hospital market share, with a year-over-year sales decline of 5.6% in the fourth quarter of 2022[85] - The company's blood stasis injection product (200mg) had a procurement volume of 1.769 million units, with a price range of 20.08 to 28 yuan per unit[71] - The company's blood stasis injection product (100mg) had a procurement volume of 2.089 million units, with a price range of 27.96 to 48.2 yuan per unit[71] - The company's blood stasis capsule product had a procurement volume of 12.938 million units, with a price range of 1.5922 to 1.6642 yuan per unit[71] - Sales of "Zhusheyong Xuesaitong" (injection) increased by 20.70% year-on-year, reaching 2,884.38 million units[173] Corporate Governance and Shareholder Rights - The company has implemented a comprehensive governance structure, ensuring equal rights for all shareholders and transparent decision-making processes[9] - The company has maintained strict compliance with insider information management and disclosure regulations[11] - The company held 8 board meetings in 2022, with 5 conducted via telecommunication and 3 combining on-site and telecommunication methods[41] - The company's dividend policy is in compliance with the company's articles of association and shareholder meeting resolutions, with clear standards and proportions[161] Financial Metrics and Cash Flow - The company's basic earnings per share (EPS) decreased by 48.74% year-over-year to 0.1969 yuan in 2022[99] - The company's diluted EPS also decreased by 48.74% year-over-year to 0.1969 yuan in 2022[99] - The weighted average return on equity (ROE) decreased by 3.04 percentage points to 2.62% in 2022[99] - The company's industrial revenue reached 234,111.89 million yuan, with a pharmaceutical industrial gross margin of 65.34%[108] - The overall gross margin of the company was 59.44% in 2022[108] - The company's sales of cardiovascular and cerebrovascular drugs increased by 74.13% year-over-year to 72,869.97 million yuan[108] - Q1 2022 revenue was RMB 1,003,658,954.36, Q2 revenue was RMB 1,474,995,212.74, Q3 revenue was RMB 837,929,544.71, and Q4 revenue was RMB 897,565,147.91[115] - Net profit attributable to shareholders in Q1 2022 was RMB 157,983,557.32, Q2 was RMB 81,173,585.54, Q3 was a loss of RMB -85,661,561.06, and Q4 was RMB 31,895,075.33[115] - Net cash flow from operating activities in Q1 2022 was RMB 77,223,705.06, Q2 was a negative RMB -98,605,456.45, Q3 was a negative RMB -5,181,535.20, and Q4 was a negative RMB -300,229,473.94[115] - Revenue for 2022 reached 4,214,148,859.72 yuan, a 2.12% increase compared to 2021[133] - Net cash flow from operating activities was -326,792,760.53 yuan, a 24.69% improvement from the previous year[140] - Net cash flow from investing activities was 283,931,024.95 yuan, a significant 167.40% increase compared to 2021[140] - Net cash flow from financing activities was -418,944,606.70 yuan, a 152.54% decrease from the previous year[140] Inventory and Asset Management - Inventory increased by 37.16% to RMB 1,005,750,391.69 in 2022, mainly due to strategic reserve increases[120] - Intangible assets grew by 265.06% to RMB 764,289,818.20, driven by increased product patent technology[120] - Development expenditure increased by 42.45% to RMB 198,491,520.56, reflecting higher R&D investment[120] - Short-term borrowings surged by 116.67% to RMB 1,301,648,472.23, primarily due to increased short-term credit loans[120] - Contract liabilities rose by 343.27% to RMB 54,886,001.28, mainly due to increased advance payments from customers[120] - Long-term borrowings decreased by 64.35% to RMB 460,000,000.00, as the company repaid long-term loans and reclassified some to short-term liabilities[120] - Monetary funds decreased by 35.44% to 1,001,392,531.66 yuan, mainly due to increased investment in fundraising projects[141] - Accounts receivable increased by 59.58% to 135,397,401.38 yuan, primarily due to increased bill settlements[141] - Restricted monetary funds totaled 19,078,340.09 yuan, mainly due to housing deposits and bank acceptance bill guarantees[143] Talent and Compensation - The company has strengthened its talent strategy by combining internal training with external recruitment, focusing on R&D and marketing talent[7] - The company's board of directors includes Chairman Fang Tonghua, who has been in the position since March 2011, with an annual pre-tax compensation of 2.7074 million yuan[152] - The company's total pre-tax compensation for all directors, supervisors, and senior management in 2022 was 8.2162 million yuan[152] - The company is focusing on improving its salary policies to maintain regional industry leadership and integrating incentive mechanisms with the salary system[156] Accounts Receivable and Bad Debt - Accounts receivable within 1 year amounted to 1,398,279,028.46 yuan, with a bad debt provision ratio of 0.50%[166] - Accounts receivable aged 1 to 2 years totaled 188,415,496.95 yuan, with a bad debt provision ratio of 5.00%[166] - Accounts receivable aged 2 to 3 years were 16,767,435.19 yuan, with a bad debt provision ratio of 20.00%[166] - Total accounts receivable stood at 1,606,977,800.91 yuan, with a total bad debt provision of 23,281,498.74 yuan[166] Industry Trends and Market Analysis - MAT sales of multinational companies in China decreased by 4.3% year-over-year in 2022, while domestic companies saw a smaller decline of 1.3%[89] - The Chinese pharmaceutical market is expected to grow at a rate of 7-8% in terms of actual drug sales volume, driven by innovation drugs and influenced by healthcare cost control and volume-based procurement[90] - In 2022, the National Medical Products Administration approved 51 new drugs, including 7 traditional Chinese medicine (TCM) new drugs[90] - Innovation drugs accounted for 25% of the total hospital drug sales in China in 2021, up 5 percentage points from 2017, with domestic innovation drugs increasing their share from 17% to 23%[90] Product and Market Share - The company has 65 products in the 2022 national medical insurance catalog, including 34 Class A and 31 Class B products, with 2 products having adjusted medical insurance notes compared to 2021[68] - The top five customers accounted for 16.44% of total annual sales, with no related party sales[176] - The top five suppliers accounted for 8.37% of total annual purchases, with no related party purchases[177] - The company has 160 R&D personnel, accounting for 5.8% of the total workforce[179] Expenses and Costs - Sales expenses decreased by 5.62% to 608.31 million yuan year-on-year[200] - Management expenses slightly decreased by 0.86% to 321.99 million yuan[200] - Financial expenses decreased by 5.04% to 135.32 million yuan[200] - Revenue from Chinese herbal medicine trade increased by 28.16%, while costs rose by 32.53% due to seasonal and regional price fluctuations[172] Government Subsidies and Other Receivables - The company has a policy for handling government subsidies, where any confirmed subsidies that need to be returned will offset the relevant deferred income balance, with any excess recorded in current profits and losses[163] - Total other receivables amounted to 823.41 million yuan, with government subsidies accounting for 658.84 million yuan[198] Leasing and Asset Recognition - The company recognizes the right to use leased assets as a lessee at the commencement of the lease term, except for simplified short-term leases and low-value asset leases[165] Business Overview and Product Information - The company's main business is in the pharmaceutical manufacturing industry, specifically in the production of traditional Chinese medicine[144] - The product "Injection of Xuesaitong (Freeze-dried)" is used for promoting blood circulation and removing blood stasis, and is classified as a prescription drug and protected traditional Chinese medicine[145] - The company's registered address is in Heilongjiang Province, and its office address is in Harbin, Heilongjiang Province[150]

证券代码：603567 证券简称：珍宝岛 重要内容提示 单位：元 币种：人民币 2023 年第一季度报告 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真实、准确、完整，不存 在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 第一季度财务报表是否经审计 一、 主要财务数据 | --- | --- | --- | |-----------------------------------------------|------------------|-------------------------------------| | 项目 | 本报告期 | 本报告期比上年同期增减 变动幅度 (%) | | 营业收入 | 1,532,479,010.19 | 52.69 | | 归属于上市公司股东的净利润 | 254,149,498.07 | 60.87 | | 归属于上市公司股东的扣除非经常 性损益的净利润 | 238,212,167.05 | 80.97 | | 经营活动产生的现金流量净额 | -153,277,856.55 | -298.49 | | 基本每股收益（元/股） | 0. ...

2022 年第三季度报告 证券代码：603567 证券简称：珍宝岛 黑龙江珍宝岛药业股份有限公司 2022 年第三季度报告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏， 并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真实、准确、完整， 不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 公司负责人、主管会计工作负责人及会计机构负责人（会计主管人员）保证季度报告中财务 信息的真实、准确、完整。 第三季度财务报表是否经审计 □是√否 一、 主要财务数据 (一)主要会计数据和财务指标 | --- | --- | --- | --- | --- | --- | |-----------------------------|-----------------|---------------------------------------|-------|------------------|--------------------------------------------| | | ...

2022 年半年度报告 公司代码：603567 公司简称：珍宝岛 黑龙江珍宝岛药业股份有限公司 2022 年半年度报告 1 / 169 2022 年半年度报告 重要提示 一、 本公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容的真实性、准确性、 完整性，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 二、 公司全体董事出席董事会会议。 三、 本半年度报告未经审计。 四、 公司负责人方同华、主管会计工作负责人王磊及会计机构负责人（会计主管人员）王磊声明： 保证半年度报告中财务报告的真实、准确、完整。 五、 董事会决议通过的本报告期利润分配预案或公积金转增股本预案 无 六、 前瞻性陈述的风险声明 √适用 □不适用 本报告中所涉及的未来计划、发展战略等前瞻性陈述,不构成公司对投资者的实际承诺,请投 资者注意投资风险。 七、 是否存在被控股股东及其关联方非经营性占用资金情况 否 八、 是否存在违反规定决策程序对外提供担保的情况？ 否 九、 是否存在半数以上董事无法保证公司所披露半年度报告的真实性、准确性和完整性 否 十、 重大风险提示 报告期内，不存在对公司生产经营产生实质性影响的特 ...

2021 年年度报告 公司代码：603567 公司简称：珍宝岛 黑龙江珍宝岛药业股份有限公司 2021 年年度报告 1 / 222 2021 年年度报告 重要提示 一、 本公司董事会、监事会及董事、监事、高级管理人员保证年度报告内容的真实性、准确性、 完整性，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 二、 公司全体董事出席董事会会议。 三、 中准会计师事务所（特殊普通合伙）为本公司出具了标准无保留意见的审计报告。 四、 公司负责人方同华、主管会计工作负责人王磊及会计机构负责人（会计主管人员）王磊声明： 保证年度报告中财务报告的真实、准确、完整。 五、 董事会决议通过的本报告期利润分配预案或公积金转增股本预案 黑龙江珍宝岛药业股份有限公司拟以2021年12月31日总股本941,963,592股为基数，向全体股 东每10股派发现金股利1.06元人民币(含税)，共计分配现金股利总额为99,848,140.76元，母公司 累计剩余未分配利润人民币2,840,224,619.68元结转下一年度。2021年度不送股，不以资本公积 金转增股本。 六、 前瞻性陈述的风险声明 √适用 □不适用 本报告 ...

证券代码：603567 证券简称：珍宝岛 公告编号：临 2022-040 黑龙江珍宝岛药业股份有限公司 关于参加"2022 年投资者网上集体接待日活动 暨业绩说明会"的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 为进一步加强与投资者的互动交流，黑龙江珍宝岛药业股份有限公司（以 下简称"公司"）将参加由黑龙江省上市公司协会联合深圳市全景网络有限公司 共同举办的"黑龙江省上市公司 2022 年度投资者网上集体接待日活动暨业绩说 明会"，现将有关事项公告如下： 为促进上市公司规范运作、健康发展，增强上市公司信息透明度，加强与广 大投资者沟通交流，进一步提升投资者关系管理水平，黑龙江省上市公司协会联 合深圳市全景网络有限公司，在"全景路演"举办"黑龙江省上市公司 2022 年 投资者网上集体接待日活动暨业绩说明会"。投资者可以登陆"全景路演"网站 （https://rs.p5w.net/html/132395.shtml）参与公司本次投资者集体接待日活 动,时间为 2022 年 5 月 12 日（周四）14:30 至 ...

2022 年第一季度报告 单位：元 币种：人民币 证券代码：603567 证券简称：珍宝岛 黑龙江珍宝岛药业股份有限公司 2022 年第一季度报告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真实、准确、完整，不存 在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 公司负责人、主管会计工作负责人及会计机构负责人（会计主管人员）保证季度报告中财务报表 信息的真实、准确、完整。 第一季度财务报表是否经审计 □是√否 一、 主要财务数据 (一)主要会计数据和财务指标 | --- | --- | --- | |-----------------------------------------------|------------------|---------------------------------------| | 项目 | 本报告期 | 本报告期比上年同期增减 \n变动幅度 (%) | | 营业收入 | 1,003,658, ...

2021 年年度报告 公司代码：603567 公司简称：珍宝岛 黑龙江珍宝岛药业股份有限公司 2021 年年度报告 1 / 217 2021 年年度报告 重要提示 一、 本公司董事会、监事会及董事、监事、高级管理人员保证年度报告内容的真实性、准确性、 完整性，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 二、 公司全体董事出席董事会会议。 三、 中准会计师事务所（特殊普通合伙）为本公司出具了标准无保留意见的审计报告。 四、 公司负责人方同华、主管会计工作负责人王磊及会计机构负责人（会计主管人员）王磊声明： 保证年度报告中财务报告的真实、准确、完整。 五、 董事会决议通过的本报告期利润分配预案或公积金转增股本预案 黑龙江珍宝岛药业股份有限公司拟以2021年12月31日总股本941,963,592股为基数，向全体股 东每10股派发现金股利1.06元人民币(含税)，共计分配现金股利总额为99,848,140.76元，母公司 累计剩余未分配利润人民币2,840,224,619.68元结转下一年度。2021年度不送股，不以资本公积 金转增股本。 六、 前瞻性陈述的风险声明 √适用 □不适用 本报告 ...

证券代码：603567 证券简称：珍宝岛 编号：2022-001 √特定对象调研□分析师会议□媒体采访□业绩说明会 投资者关系活 □新闻发布会□路演活动□现场参观 动类别 □其他（请文字说明其他活动内容） 参与单位名称 上海冰河资本刘春茂、东方阿尔法基金乔海英、长江证券朱学辉、 泰康资产杨磊 及人员姓名 公司领导对公司基本情况做了系统介绍，参会机构与公司相 关领导进行了沟通交流，主要内容如下： 1、中药创新药未来的布局？对公司影响如何？ 答：公司正在布局中药创新药产品，根据不同品种特点做到 投资者关系活动 创新药上市还需要时间。现在有的品种马上进行二期临床，还有 主要内容介绍 的品种在做药学研究，预计明年年底有望拿到批件，还有其他一 些已经立项。其他中药品种的补充也在不断引进有临床和市场价 值的产品，不断补充短线产品和几个大的品种，今年有销售预期。 中药创新药的研发及引进，将会进一步提升公司主营业务产品核 黑龙江珍宝岛药业股份有限公司 投资者关系活动记录表 | --- | --- | --- | |----------------|--------------------------------------- ...

2021 年第三季度报告 单位：元 币种：人民币 1 / 12 证券代码：603567 证券简称：珍宝岛 黑龙江珍宝岛药业股份有限公司 2021 年第三季度报告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真实、准确、完整， 不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 公司负责人、主管会计工作负责人及会计机构负责人（会计主管人员）保证季度报告中财务 报表信息的真实、准确、完整。 第三季度财务报表是否经审计 □是√否 一、 主要财务数据 主要会计数据和财务指标 本报告期比 年初至报告 | --- | --- | --- | --- | --- | |------------------------------------------------|------------------|---------------------------|------------------|---------------------- ...