证券代码：688658 证券简称：悦康药业 公告编号：2025-025 悦康药业集团股份有限公司 自愿披露关于注射用更昔洛韦 通过仿制药一致性评价的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 剂型：注射剂 规格：0.5g 注册分类：化学药品 原药品批准文号：国药准字 H20053671 上市许可持有人：悦康药业集团股份有限公司 审批结论：根据《中华人民共和国药品管理法》、《国务院关于改革药品医 疗器械审评审批制度的意见》（国发〔2015〕44 号）、《关于仿制药质量和疗 效一致性评价工作有关事项的公告》（2017 年第 100 号）和《国家药监局关于 开展化学药品注射剂仿制药质量和疗效一致性评价工作的公告》（2020 年第 62 号）的规定，经审查，本品符合药品注册的有关要求，批准本品增加 0.5g 规格 的补充申请，核发药品批准文号，本品通过仿制药质量和疗效一致性评价。 二、药品的相关信息 注射用更昔洛韦主要用于治疗危及生命或视觉的免疫缺陷患者的巨细胞病 毒感染，以及预防器官移植病人的巨细胞病毒感染。 近日，悦 ...

证券代码：688658 证券简称：悦康药业 公告编号：2025-023 悦康药业集团股份有限公司 关于 2025 年第一季度计提资产减值准备的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 1-1 对于存在客观证据表明存在减值，以及其他适用于单项评估的应收票据、 应收账款，其他应收款、应收款项融资等单独进行减值测试，确认预期信用损 失，计提单项减值准备。对于不存在减值客观证据的应收票据、应收账款、其 他应收款、应收款项融资或当单项金融资产无法以合理成本评估预期信用损失 的信息时，本公司依据信用风险特征将应收票据、应收账款、其他应收款、应 收款项融资等划分为若干组合，在组合基础上计算预期信用损失。 经测试，2025 年第一季度计提信用减值损失金额共计-1,226,553.19 元。 悦康药业集团股份有限公司（以下简称"公司"）于 2025 年 4 月 28 日召 开第二届董事会第十九次会议、第二届监事会第十七次会议，分别审议通过了 《关于 2025 年第一季度计提资产减值准备的议案》。现将相关事项公告如下： 一、计提资 ...

证券代码：688658 证券简称：悦康药业 公告编号：2025-024 悦康药业集团股份有限公司 关于召开 2025 年第一季度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 会议召开时间：2025 年 5 月 16 日（星期五）9:00-10:00 会 议 召 开 地 点 ： 上 海 证 券 交 易 所 上 证 路 演 中 心 （ 网 址 ： https://roadshow.sseinfo.com/） 会议召开方式：上证路演中心网络互动 公司已于 2025 年 4 月 29 日发布公司《2025 年第一季度报告》，为便于广大 投资者更全面深入地了解公司 2025 年第一季度经营成果、财务状况，公司计划 于 2025 年 5 月 16 日（星期五）9:00-10:00 举行 2025 年第一季度业绩说明会， 就投资者关心的问题进行交流。 一、说明会类型 本次投资者说明会以网络互动形式召开，公司将针对 2025 年第一季度的经 营成果及财务指标的具体情况与投资者进行互动交流和沟通，在信息披露允 ...

Financial Performance - The company's revenue for Q1 2025 was ¥577,383,322.42, representing a decrease of 40.35% compared to ¥967,900,022.68 in the same period last year[4] - The net profit attributable to shareholders was a loss of ¥49,271,134.83, a decline of 171.09% from a profit of ¥69,305,423.83 in the previous year[4] - The net cash flow from operating activities decreased by 44.54%, amounting to ¥81,041,633.19 compared to ¥146,130,897.27 in the prior year[4] - Total operating revenue for Q1 2025 was ¥577.38 million, a decrease of 40.4% compared to ¥967.90 million in Q1 2024[17] - Net profit for Q1 2025 was a loss of ¥49.50 million, compared to a profit of ¥69.12 million in Q1 2024, indicating a significant decline[18] - Operating profit for Q1 2025 was a loss of ¥58.45 million, contrasting with a profit of ¥80.36 million in Q1 2024[17] - Cash flow from operating activities for Q1 2025 was ¥81.04 million, down 44.5% from ¥146.13 million in Q1 2024[21] Assets and Liabilities - The total assets at the end of the reporting period were ¥5,611,332,242.14, a decrease of 2.21% from ¥5,738,112,424.72 at the end of the previous year[5] - The company's current assets totaled RMB 3,037,807,721.74, down from RMB 3,157,931,976.13, indicating a decrease of about 3.8%[12] - Cash and cash equivalents increased to RMB 1,454,983,942.63 from RMB 1,331,795,660.80, representing a growth of approximately 9.2%[12] - Inventory decreased significantly from RMB 757,335,702.72 to RMB 645,468,495.43, a reduction of around 14.7%[12] - Total liabilities decreased from RMB 2,153,155,749.09 to RMB 2,075,873,810.65, a decline of about 3.6%[14] - The company's equity attributable to shareholders decreased from RMB 3,577,629,966.77 to RMB 3,528,358,831.94, a decrease of approximately 1.4%[14] - The company reported a short-term loan of RMB 103,133,365.43, down from RMB 112,965,265.65, reflecting a decrease of about 8.0%[14] - The company's accounts receivable stood at RMB 575,284,268.66, a slight decrease from RMB 611,698,533.96, indicating a reduction of approximately 6.0%[12] - The company's total non-current assets were RMB 2,573,524,520.40, slightly down from RMB 2,580,180,448.59, reflecting a decrease of about 0.3%[13] Research and Development - Research and development expenses totaled ¥99,271,226.53, which is an increase of 2.27% year-over-year, and accounted for 17.19% of total revenue, up by 10.03 percentage points[5] - The company is actively promoting and increasing investment in key R&D projects, including small nucleic acid drugs and peptide drugs, to maintain industry leadership[7] - Research and development expenses for Q1 2025 were ¥97.17 million, an increase of 13.6% from ¥85.50 million in Q1 2024[17] Sales and Marketing - The company plans to optimize sales strategies and maintain core sales channels to address the decline in revenue and profit[7] - Sales expenses for Q1 2025 were ¥130.66 million, down 55.6% from ¥294.03 million in Q1 2024[17] Financial Metrics - The weighted average return on equity was -1.39%, down by 3.31 percentage points from 1.92% in the previous year[4] - The basic and diluted earnings per share were both -¥0.11, a decrease of 173.33% from ¥0.15 in the same period last year[4] - The company incurred a financial expense of ¥3.61 million in Q1 2025, compared to a financial income of ¥0.54 million in Q1 2024[17]

Financial Performance - The company reported a basic earnings per share of -0.1100 yuan for Q1 2025, a decrease of 173.33% compared to 0.1500 yuan in Q1 2024 [1] - The total revenue for Q1 2025 was 5.77 billion yuan, down 40.39% from 9.68 billion yuan in Q1 2024 [1] - The net profit for Q1 2025 was -0.49 billion yuan, representing a decline of 171.01% from a profit of 0.69 billion yuan in Q1 2024 [1] - The return on equity for Q1 2025 was -1.39%, a significant drop from 1.92% in Q1 2024 [1] Shareholder Structure - The top ten unrestricted shareholders collectively hold 25,836.88 million shares, accounting for 57.42% of the circulating shares, with a decrease of 1,485.70 million shares compared to the previous period [1] - The largest shareholder, Fuyang Jingyue Yongshun Information Consulting Co., Ltd., holds 18,024.01 million shares, representing 40.05% of the total share capital, with no change [2] - Hong Kong Central Clearing Limited and China Merchants Medical Health Industry Stock have exited the top ten shareholders list [2] Dividend Policy - The company has announced that it will not distribute dividends or transfer shares this time [3]

本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 悦康药业集团股份有限公司（以下简称"公司"或"悦康药业"）控股股东 阜阳京悦永顺信息咨询有限公司（以下简称"京悦永顺"）持有公司股份 180,240,120 股，占公司总股本的比例为 40.05%。截至本公告披露日，本次京悦 永顺持有的本公司 26,500,000 股无限售流通股股票将被司法拍卖。 目前拍卖事项尚在公示阶段，后续可能涉及竞拍、缴款、法院执行法定 程序、股权变更过户等环节，存在一定的不确定性。公司将根据最终结果，依法 履行相应的信息披露义务。 拍卖成交后，买受人后续减持股票需符合《上市公司股东减持股份管理 暂行办法》及《上海证券交易所上市公司自律监管指引第 15 号——股东及董事、 高级管理人员减持股份（2025 年 3 月修订）》等相关规定。同时买受人还需遵守 中国证监会、上海证券交易所等关于上市公司信息披露的相关规定，依法履行信 息披露义务。股票后续能否立即在二级市场进行交易，具体的情况应以监管部门 的认定为准。 京悦永顺持有的部分本公司股份 ...

证券代码：688658 证券简称：悦康药业 公告编号：2025-020 悦康药业集团股份有限公司 关于控股股东部分股份被冻结的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： 一、公司股东股份被冻结的具体情况 股东 名称 是否为控 股股东及 其一致行 动人 冻结股份数 量 占其 所持 股份 比例 占公 司总 股本 比例 冻结股 份是否 为限售 股 冻结起始日 冻结到期日 冻结申请人 冻结 原因 京悦 永顺 是 13,130,000 7.28% 2.92% 否 2025 年 1 月 20 日 2028 年 1 月 19 日 宁波惟精昫竔 股权投资合伙 企业（有限合 伙）、宁波焓湜 枫德股权投资 合伙企业（有限 合伙） 财产 保全 是 2,066,002 1.15% 0.46% 否 2025 年 1 月 27 日 2028 年 1 月 26 日 合计 - 15,196,002 8.43% 3.38% - - - - - 司法冻结，具体情况如下： 悦康药业集团股份有限公司（以下简称"公司"）控股股东阜阳京悦永 ...

Investment Rating - The industry investment rating is "Positive" (maintained) [1] Core Viewpoints - The Chinese traditional medicine sector is expected to experience a relative recovery in 2025, with opportunities in key lines and individual stocks [4][12] - The overall market demand is gradually recovering due to the end of the pandemic and the impact of influenza, leading to a high base and inventory digestion pressure in 2024 [4][12] - The State Council's March 2025 document supports the quality improvement of traditional Chinese medicine, which is expected to stimulate innovation and commercialization of high-quality products [5][13] Summary by Sections Industry Trends - In April 2025, the pharmaceutical and biotechnology sector rose by 1.16%, outperforming the CSI 300 index by 0.77 percentage points [6][15] - The medical research outsourcing sector saw the largest increase of 6.34%, while the vaccine sector experienced the largest decline of 3.78% [20][21] Investment Opportunities - Four main investment lines are identified: 1. Innovative R&D-focused companies with strong capabilities, benefiting from accelerated approvals and optimized procurement, recommended stocks include Fangsheng Pharmaceutical, Yuyuan Pharmaceutical, Tianshili, and Yiling Pharmaceutical [5][14] 2. State-owned enterprises undergoing operational efficiency improvements, recommended stocks include Dong'e Ejiao, Jiangzhong Pharmaceutical, and Kunming Pharmaceutical [5][14] 3. Companies with strong brand power and relatively scarce products, recommended stocks include Zoli Pharmaceutical and Lingrui Pharmaceutical [5][14] 4. Companies experiencing turnaround and valuation recovery, recommended stock includes Jichuan Pharmaceutical [5][14] Market Performance - The traditional Chinese medicine sector has faced pressure since the pandemic, but the situation is expected to improve in 2025 as macro disturbances ease [4][12] - The price index of traditional Chinese medicine materials has been declining since mid-July 2024, which is expected to alleviate the gross margin pressure on companies in 2025 [5][12]

Market Overview - The A-share market indices continued to rise, achieving a five-day consecutive increase, with a total trading volume of 1.31 trillion yuan, a decrease of 78 billion yuan from the previous trading day [1] - The Hainan sector experienced significant growth, while a few sectors such as shipping ports and the茅指数 saw declines [1] Stock Performance - A total of 103 stocks hit the daily limit, with 13 stocks achieving consecutive limit-ups, and 31 stocks failed to close at the limit, resulting in a limit-up rate of 77% (excluding ST and delisted stocks) [3] - Notable stocks included: - Guofang Group achieved a 7-day limit-up, driven by retail and brokerage investments [4] - Zhongqi New Material saw a 10.01% increase, marking its 9th day with 7 limit-ups, influenced by semiconductor equipment [4] - Zhongyuan Home achieved a limit-up, marking its 5th consecutive limit-up, supported by the sofa and e-commerce sectors [4] Institutional Trading - The top three net buying stocks on the Dragon and Tiger list were Hunan Gold, Tianhe Magnetic Materials, and Yuekang Pharmaceutical, with net purchases of 179 million yuan, 157 million yuan, and 106 million yuan, respectively [6] - The top three net selling stocks were Baolingbao, Hongbaoli, and Ouyagu, with net sales of 64.35 million yuan, 54.92 million yuan, and 46.72 million yuan, respectively [6] Sector Highlights - Hunan Gold's stock price surged due to rising gold prices, with spot gold breaking historical highs at $3,245.45 per ounce, and forecasts from Goldman Sachs and UBS predicting further increases [7] - Yuekang Pharmaceutical reported a 42.2 million yuan R&D investment in 2024, accounting for 11.16% of its revenue, reflecting a 0.78 percentage point increase year-on-year [12] - Baolingbao's stock experienced abnormal fluctuations, with a cumulative increase of over 20% in three consecutive trading days, while the company maintains a diverse product range in functional sugars [13] Notable Stock Movements - Kexing Pharmaceutical saw a significant increase of 16.83%, with a trading volume of 288 million yuan and a net institutional purchase of 89.31 million yuan [16] - Ha Sanlian's stock rose by 3.01%, with a trading volume of 787 million yuan and a net institutional purchase of 49.39 million yuan [16] - Qingdao Jinwang's stock increased by 5.41%, with a trading volume of 2.6 billion yuan and a net institutional purchase of 44.02 million yuan [16]

截至2025年4月14日 14:12，上证科创板综合指数(000680)上涨0.61%，成分股悦康药业(688658)上涨 19.91%，科兴制药(688136)上涨16.90%，华丰科技(688629)上涨11.72%，路德环境(688156)上涨8.36%， 南亚新材(688519)上涨8.04%。 数据显示，截至2025年3月31日，上证科创板综合指数(000680)前十大权重股分别为海光信息(688041)、 寒武纪(688256)、中芯国际(688981)、金山办公(688111)、中微公司(688012)、传音控股(688036)、联影 医疗(688271)、百利天恒(688506)、澜起科技(688008)、晶科能源(688223)，前十大权重股合计占比 22.34%。 科创综指ETF鹏华(589680)，场外联接A：023757；联接C：023758。 以上内容与数据，与界面有连云频道立场无关，不构成投资建议。据此操作，风险自担。 申万宏源证券指出，AI产业链持续突破——国产算力突围×物理智能革命×机器人量产元年，市场每次 回调都是筹码再沉淀。后续AI产业链催化节点或集中在5-6月，届时阿里、 ...