登录新浪财经APP 搜索【信披】查看更多考评等级 本公司及董事会全体成员保证信息披露的内容真实、准确和完整，没有虚假记载、误导性陈述或者重大 遗漏。 一、股票交易异常波动的情况介绍 南华生物医药股份有限公司（以下简称"公司"或"南华生物"）股票（证券简称：*ST生物（维权），证 券代码：000504）于2025年8月12日、2025年8月13日、2025年8月14日连续三个交易日内收盘价格跌幅 偏离值累计超过12%，根据《深圳证券交易所交易规则》的有关规定，属于股票异常波动情形。 二、公司关注并核实情况 （一）公司核查情况 针对公司股票交易异常波动，公司对有关事项进行了核查，对影响公司股票异常波动的情况说明如下： 1.公司前期披露的信息不存在需要更正、补充之处； 2.近期公共传媒未出现报道了可能或已经对本公司股票交易价格产生较大影响的未公开重大信息； 2.不存在买卖南华生物股票的情形； 3.不存在需要说明的其他重大情形。 三、是否存在应披露而未披露信息的说明 本公司董事会确认，除前述事项外，公司目前没有任何根据《深圳证券交易所股票上市规则》规定应予 以披露而未披露的事项；董事会也未获悉本公司有根据《深圳证券交 ...

证券代码：000504 证券简称：*ST 生物 公告编号：2025-048 南华生物医药股份有限公司 3.近期公司经营情况及内外部经营环境未发生重大变化； 4.公司不存在涉及要参照相关公告格式作出说明和披露的其他事项； 股票交易异常波动公告 5.公司不存在需要根据《深圳证券交易所股票上市规则》等有关规定应予以 披露而未披露的事项； 本公司及董事会全体成员保证信息披露的内容真实、准确和完整，没有虚 假记载、误导性陈述或者重大遗漏。 一、股票交易异常波动的情况介绍 南华生物医药股份有限公司（以下简称"公司"或"南华生物"）股票（证 券简称：*ST生物，证券代码：000504）于2025年8月12日、2025年8月13日、2025 年8月14日连续三个交易日内收盘价格跌幅偏离值累计超过12%，根据《深圳证券 交易所交易规则》的有关规定，属于股票异常波动情形。 二、公司关注并核实情况 （一）公司核查情况 针对公司股票交易异常波动，公司对有关事项进行了核查，对影响公司股票 异常波动的情况说明如下： 1.公司前期披露的信息不存在需要更正、补充之处； 2.近期公共传媒未出现报道了可能或已经对本公司股票交易价格产生较大 影响 ...

Market Overview - On August 14, the medical services sector declined by 0.47%, with XD Zhaoyan leading the drop [1] - The Shanghai Composite Index closed at 3666.44, down 0.46%, while the Shenzhen Component Index closed at 11451.43, down 0.87% [1] Top Gainers in Medical Services - Nanjing Momo Biological Technology (688265) saw a closing price of 60.60, up 16.20% with a trading volume of 45,800 shares and a transaction value of 262 million [1] - Innovation Medical (002173) closed at 24.92, up 10.02% with a trading volume of 1,071,000 shares and a transaction value of 2.609 billion [1] - Sanbo Brain Science (301293) closed at 67.82, up 8.51% with a trading volume of 396,800 shares and a transaction value of 2.618 billion [1] Top Losers in Medical Services - XD Zhaoyan (603127) closed at 32.21, down 5.74% with a trading volume of 455,800 shares and a transaction value of 1.497 billion [2] - Chengda Pharmaceutical (301201) closed at 27.34, down 5.50% with a trading volume of 98,100 shares and a transaction value of 276 million [2] - ST Biological (000504) closed at 10.75, down 5.04% with a trading volume of 110,000 shares and a transaction value of 120 million [2] Capital Flow Analysis - The medical services sector experienced a net outflow of 364 million from institutional investors, while retail investors saw a net inflow of 138 million [2] - Notable net inflows from retail investors were observed in Innovation Medical (002173) with 117 million, while significant outflows were noted in Sanbo Brain Science (301293) with 46 million [3]

Core Viewpoint - The company *ST Biopharmaceuticals is planning to acquire a 51% stake in Hunan Huize Biopharmaceutical Technology Co., Ltd. in a cash transaction, which is expected to constitute a significant asset restructuring but will not involve issuing shares or changing control [1][4]. Group 1: Acquisition Details - The acquisition aims to enhance the company's biopharmaceutical business and improve profitability and risk resistance [5]. - Hunan Huize, established in 2014, specializes in drug research and clinical evaluation, with over 85% of its revenue coming from clinical evaluation services [4]. - The acquisition is still in the planning stage, and the specific transaction terms will be finalized after due diligence and negotiations [4]. Group 2: Financial Performance - On August 12, *ST Biopharmaceuticals' stock hit the daily limit down, closing at 11.91 yuan, following two consecutive days of limit up [2]. - The company has faced financial difficulties, with a reported revenue of 134 million yuan and a net loss of 19.85 million yuan for 2024 [8]. - The company is projected to have a revenue of 49 to 52 million yuan in the first half of the year, indicating a year-on-year decline [8]. Group 3: Historical Context - The company has a history of financial struggles, having been warned of delisting multiple times due to consecutive years of negative net profits [6][7]. - Previous attempts to improve financial performance included a failed acquisition of Yuan Tai Biopharmaceuticals in 2017, which was later sold due to high R&D costs and poor financial conditions [9][11].

Market Performance - On August 13, the medical services sector rose by 4.02%, led by Innovative Medical [1] - The Shanghai Composite Index closed at 3683.46, up 0.48%, while the Shenzhen Component Index closed at 11551.36, up 1.76% [1] Individual Stock Performance - The table lists various stocks in the medical services sector, with notable declines including *ST Bio down 4.95% and ST Zhongzhu down 2.66% [1] - Other stocks such as Lanwei Medical and Baicheng Pharmaceutical also experienced minor declines of 1.76% and 1.59% respectively [1] Capital Flow Analysis - The medical services sector saw a net inflow of 1.962 billion yuan from institutional investors, while retail investors experienced a net outflow of 1.888 billion yuan [3] - Notable stocks with significant net inflows from institutional investors include Yaoming Kande with 1.13 billion yuan and Kanglong Huacheng with 248 million yuan [3] - Conversely, retail investors showed significant outflows from stocks like Yaoming Kande and Kanglong Huacheng, indicating a shift in investor sentiment [3]

本次签署的《股权收购意向协议》系各方就收购事宜达成的初步意向协议，旨在表达各方合作意向，具体的交易方案及交易条款以各方签署的正式协议为 准。本次交易尚处于筹划阶段，相关事项尚存在不确定性。 慧泽医药成立于2014年9月25日，注册资本为1109.8万元，法定代表人为易木林，是一家专注于药物研发及临床评价的专业CRO公司，85%以上的收入来源 于临床评价服务。公司是国家级高新技术企业、国家级专精特新"小巨人"企业等。 股权方面，目前，慧泽医药由程泽能持股51.81%，易木林持股38.3%，长沙君合致远企业管理咨询合伙企业（有限合伙）持股8.37%，长沙市履方医药信息 咨询合伙企业（有限合伙）持股1.52%。 截至目前，慧泽医药与国内外三百多家医药（含器械）A证企业（A证企业即自行生产的药品上市许可持有人（MAH），批准文号与生产主体为同一主 体）、B证企业（B证企业即委托生产的药品上市许可持有人（MAH），自身不生产，委托符合条件的药品生产企业生产）、C证企业（C证企业即接受委托 的药品生产企业（受托方））及药学CRO、科研院所等建立了长期、友好的战略合作伙伴关系，已完成各类型技术服务项目总计超过1000项。 ...

Core Viewpoint - The company *ST Bio plans to acquire 51% of Hunan Huize Biomedical Technology Co., Ltd. in a cash transaction, which is expected to enhance its core business and improve profitability, while also addressing its ongoing delisting risk [1][6][9]. Group 1: Acquisition Details - The acquisition is expected to constitute a significant asset restructuring but will not involve issuing new shares or changing control of the company [2]. - The acquisition agreement has been signed, and the specific terms will be finalized after due diligence and negotiations [6]. - Huize Biomedical, established in 2014, specializes in drug research and clinical evaluation, with over 85% of its revenue coming from clinical evaluation services [7]. Group 2: Financial Performance and Risks - The company has faced continuous losses, leading to multiple delisting warnings since 2016, with its stock currently labeled as *ST Bio due to negative net profits in recent years [10][11]. - In 2024, *ST Bio reported revenues of 134 million yuan and a net loss of 19.85 million yuan, with expectations of further declines in revenue for the first half of 2025 [11]. - The company previously attempted to improve its financial situation through the acquisition of Yuan Tai Bio in 2017, but ultimately sold it due to high R&D costs and financial strain [14][15]. Group 3: Strategic Intent - The acquisition of Huize Biomedical is aimed at extending the company's biopharmaceutical business and enhancing its profitability and risk resilience [7]. - The integration of drug research and clinical evaluation services is expected to create strong synergies and improve operational efficiency [7].

Core Viewpoint - *ST Bio is undertaking a new round of restructuring efforts to avoid delisting risks by planning to acquire a 51% stake in Hunan Huize Biomedical Technology Co., Ltd. through cash payment, aiming to enhance its profitability and operational efficiency [1][4][10]. Group 1: Acquisition Details - On August 12, *ST Bio announced the signing of a share acquisition intention agreement to acquire 51% of Huize Biomedical, a company specializing in drug research and clinical evaluation, with over 85% of its revenue coming from clinical evaluation services [4][10]. - The acquisition is intended to extend *ST Bio's biopharmaceutical business and improve its main business profitability, while also enhancing operational efficiency through asset integration [4][10]. Group 2: Stock Performance - Prior to the restructuring announcement, *ST Bio's stock experienced two consecutive days of trading at the upper limit, with a peak price of 12.54 yuan per share on August 11, marking a new high for the year and a trading volume of 1.07 billion yuan [5][6]. - Following the announcement, *ST Bio's stock hit the lower limit on August 12, closing at 11.91 yuan per share, reflecting a decline of 5.02% [6]. Group 3: Financial Status and Risks - *ST Bio has been under delisting risk warning since April 30, 2023, due to negative financial performance, including a projected revenue of approximately 1.34 billion yuan and a net loss of about 19.85 million yuan for 2024 [8][9]. - The company has taken multiple self-rescue measures, including selling loss-making subsidiaries and restructuring its board of directors to improve its financial situation and operational capabilities [10][11].

Group 1 - The stock price of *ST Bio (000504) closed at 11.91 yuan, down 5.02%, with a turnover rate of 1.1% and a trading volume of 36,100 shares, amounting to 43.0165 million yuan [1] - The net outflow of main funds was 12.0255 million yuan, accounting for 27.96% of the transaction amount, with large orders showing a net outflow of 12.9843 million yuan, which is 30.18% of the transaction amount [1] - The latest financial report for *ST Bio shows total operating revenue of 22.4536 million yuan, a year-on-year decrease of 13.55%, while net profit attributable to shareholders was 2.2186 million yuan, an increase of 19.92% [1] Group 2 - Nanhua Biological Pharmaceutical Co., Ltd. was established in 1991 and is primarily engaged in the pharmaceutical manufacturing industry, with a registered capital of 3,300.23098 million yuan and paid-in capital of 3,115.73901 million yuan [2] - The company has made investments in 11 enterprises and participated in 7 bidding projects, holding 46 trademark registrations and 4 patents [2]

消息面上，*ST生物发布公告称，公司正在筹划以现金方式收购湖南慧泽生物医药科技有限公司51%股 权。在披露重组公告前，*ST生物连续两个交易日涨停。 北京商报讯（记者 丁宁）8月12日，*ST生物（000504）开盘跌停，报跌停价11.91元/股，跌幅为 5.02%。 ...