本公司及董事会全体成员保证信息披露的内容真实、准确和完整，没 有虚假记载、误导性陈述或重大遗漏。 2025年5月14日，公司全资子公司华兰生物工程重庆有限公司收到重庆市卫 生委员会印发的重庆市丰都县华兰单采血浆站（以下简称"丰都浆站"）《单采血 浆许可证》，主要信息如下： 机构名称：重庆市丰都县华兰单采血浆站 证券代码：002007 证券简称：华兰生物 公告编号：2025-017 华兰生物工程股份有限公司 关于公司取得单采血浆许可证的公告 采浆区域（范围）：重庆市丰都县 有效期限：自2025年5月14日至2027年5月13日 丰都浆站自取得《单采血浆许可证》之日起可正式采浆。丰都浆站实现采浆 将有利于提升公司原料血浆供应能力，对公司长期发展具有积极作用。 特此公告。 华兰生物工程股份有限公司董事会 业务项目：机采单采普通原料血浆、机采单采破伤风免疫原料血浆、机采单 采狂犬免疫原料血浆、机采单采乙肝免疫原料血浆 许可证号：50023016F2009031 2025年5月15日 ...

Core Viewpoint - The blood products sector is experiencing revenue growth among listed companies, but profitability is declining due to price reductions driven by increased competition and centralized procurement policies [1][2]. Group 1: Company Performance - In 2024, all nine listed companies in the blood products sector achieved revenue growth, with seven companies reporting an increase in net profit [1]. - In Q1 2024, eight companies reported a decline in net profit year-on-year, including Shanghai Raist and Tian Tan Biological, with declines of 25.20% and 22.90% respectively [1][2]. - Tian Tan Biological attributed its profit decline to a greater reduction in product prices than the increase in sales volume, primarily due to intensified market competition and centralized procurement [2][5]. - Shanghai Raist's net profit decline was also linked to increased credit impairment losses, which surged by 481% due to a rise in accounts receivable [2]. Group 2: Market Dynamics - The price of human albumin has been decreasing, with terminal prices dropping by 10% and 20% for human albumin and intravenous immunoglobulin respectively in Q1 2024 [5]. - The blood products market is characterized by a limited number of qualified players, with fewer than 30 companies holding production qualifications [1]. - The industry is facing pressure from imported human albumin, which is expected to account for 68% of total batch issuance in 2024, creating competitive challenges for domestic producers [7][12]. Group 3: Industry Trends - Centralized procurement has been a significant factor in price reductions, but its impact is considered manageable due to the rigid clinical demand for blood products [6]. - The blood products industry is heavily reliant on plasma supply, with a noted shortage in domestic plasma availability to meet market demand [7][12]. - Companies are actively pursuing acquisitions of plasma collection stations to secure raw material supply, indicating a competitive landscape for plasma resources [14][15].

Core Insights - The Chinese biotechnology industry, focusing on biopharmaceuticals, biomanufacturing, and bioagriculture, is experiencing high-quality development supported by national policies, with a projected industry scale of 21.4 trillion yuan in 2024, representing a year-on-year growth of 3.88% [1][8] - Technological innovation is identified as the core engine for industry advancement, with significant breakthroughs in gene editing, synthetic biology, and cell therapy, enhancing China's competitive position in the global biotechnology landscape [1][8] Industry Overview - The biotechnology sector encompasses living organisms and is classified based on similarities in morphology and physiology, aiding in understanding evolutionary relationships [2] - The industry has evolved through five stages, from initial laboratory research in the 1980s to a focus on commercialization and internationalization in recent years [3][4][5] Market Scale - The biopharmaceutical sector is projected to face pricing pressures, with the PPI index for biopharmaceutical manufacturing at 95.7, down 4.3% year-on-year as of March 2025, yet the demand for biopharmaceuticals is expected to grow due to aging populations and increased health awareness [10] - The biomass power generation capacity in China is expected to reach 45.99 million kilowatts by 2024, with a year-on-year growth of 4.19%, indicating a significant role in the low-carbon energy transition [12] Key Enterprises - Major players in the biopharmaceutical sector include Huazhong Biotech, which has a comprehensive blood product portfolio and a significant vaccine production platform, and Longping High-Tech, known for its hybrid rice innovations and international breeding initiatives [18][20] - The biomanufacturing and bioenergy sectors are led by companies like Guoneng Bio and Malu Bio, focusing on biomass power generation and organic waste treatment, respectively [15][16] Industry Development Trends - Technological innovation is driving breakthroughs across multiple fields, including personalized medicine in biopharmaceuticals and enhanced efficiency in bioenergy production [22][23] - The integration of biomanufacturing and bioagriculture is expected to yield innovative solutions, improving resource utilization and creating a circular economy [25]

华兰生物工程股份有限公司投资者关系活动记录表 证券代码：002007 证券简称：华兰生物 答：您好！目前国内主要有三家企业开展重组人血白蛋白的研发，截止 目前均未取得《药品注册证书》，未获批上市，后续若获准上市且产品质量 稳定、成本可控，可适当缓解国内人白供应进口占比较高的局面，公司正在 对重组人血白蛋白各种生产表达系统进行对比评估，包含：酵母表达系统、 植物细胞表达系统、细菌表达系统。 3、问：贵公司贝伐单抗已经上市销售，请问 2025 年 1 季度是否产生销 售收入，未来 1-2 年是否有新产品上市？ 答：我公司贝伐单抗 2024 年底取得《药品注册证书》，可以正式生产 和销售，2025 年 1 季度开始有一定金额的销售收入；基因公司已于 2024 年 11 月份向国家药监局递交了利妥昔单抗注射液的药品注册上市许可申请并 被受理；阿达木单抗、曲妥珠单抗、地舒单抗处于 III 期临床阶段；伊匹 木单抗、帕尼单抗处于 I 期临床阶段，预计未来三年华兰基因会有 1-3 个 品种陆续上市，丰富公司的产品梯队。 4、问：公司在 2024 年如何提高运营效率，实现公司高质量发展？ | | simonsun；KITMC ...

Investment Rating - The report maintains a "Buy" rating for the company [5][8]. Core Views - The company demonstrated resilience with revenue and profit growth in Q1 2025 despite challenges in the blood products industry, with revenue, net profit attributable to the parent, and net profit excluding non-recurring items increasing by 10.2%, 19.6%, and 35.4% year-over-year, respectively [1]. - The company is expected to benefit from increased plasma collection and recovery in vaccine sales, leading to double-digit revenue growth in 2025 [2][5]. Summary by Sections Financial Performance - In Q1 2025, the company reported revenues of 8.7 billion RMB, net profit attributable to the parent of 3.1 billion RMB, and net profit excluding non-recurring items of 3.0 billion RMB, reflecting year-over-year increases of 10.2%, 19.6%, and 35.4% respectively [1]. - The blood products segment saw revenue growth, with albumin revenue exceeding 3 billion RMB and immunoglobulin revenue surpassing 2 billion RMB [2]. Growth Drivers - The company’s plasma collection volume is projected to grow by 16% in 2025, supported by the addition of new plasma collection stations [2]. - Vaccine sales are expected to recover in 2025 as the market normalizes and competition stabilizes, following a seasonal decline in Q1 2025 [2]. Product Pipeline - The company has several products in development, including high-concentration immunoglobulin and various vaccines, with significant progress in clinical trials [4]. - The approval of biosimilars such as Bevacizumab and Rituximab is anticipated to contribute to revenue growth in the coming years [3]. Valuation and Forecast - The report projects net profits for 2025, 2026, and 2027 to be 13.7 billion RMB, 17.1 billion RMB, and 20.5 billion RMB respectively, with a target price set at 19.40 RMB based on a 26x PE ratio for 2025 [5][9].

Core Viewpoint - The blood products industry is experiencing a significant divergence in performance among companies, with some reporting growth while others face declines in revenue and profit [1][2]. Group 1: Company Performance in 2024 - Shanghai Laisai (002252) and Tiantan Biological (600161) reported revenue growth of 2.67% and 16.44% respectively, with net profits increasing by 23.25% and 39.58% [1]. - Hualan Biological (002007), Boya Biological (300294), and Bohui Innovation (300318) experienced revenue declines of 18.02%, 34.58%, and 18.53% respectively, while Hualan's net profit fell by 26.57% [1]. - Bohui Innovation managed to turn a profit with a net profit of 0.09 billion yuan, compared to a loss in the previous year [1]. Group 2: Q1 2025 Performance - In Q1 2025, Tiantan Biological, Hualan Biological, and Boya Biological continued to show revenue growth, while Shanghai Laisai, Tiantan Biological, and Paillin Biological saw revenue declines of 2.45%, 0.57%, and 14% respectively [1]. - Hualan Biological's net profit increased by 19.62%, while Shanghai Laisai and Tiantan Biological reported net profit declines of 25.2% and 22.9% respectively [1]. - The decline in profits for Tiantan Biological was attributed to a decrease in product prices that outweighed the benefits of increased sales volume [1]. Group 3: Market Dynamics - The blood products market is expected to maintain stable growth in 2024, with significant competition in the human albumin market due to increased imports [2][3]. - The cancellation of certain medical insurance restrictions is expected to release market demand for coagulation factor products, contributing to their growth [2]. - The overall price trend for blood products is declining, influenced by increased competition and supply exceeding demand for certain products [3]. Group 4: Industry Consolidation - The blood products industry is characterized by high entry barriers, with fewer than 30 companies currently operating due to strict regulations on blood product production [6][7]. - Recent mergers and acquisitions are expected to enhance industry concentration, with leading companies gaining competitive advantages through resource acquisition [6][7]. - Companies like Tiantan Biological and Shanghai Laisai have made significant acquisitions to expand their production capabilities and market presence [7]. Group 5: Market Size and Growth Projections - The blood products market in China reached a scale of 600 billion yuan in 2024, with projections to grow to 780 billion yuan by 2027, reflecting a compound annual growth rate of 11.6% from 2022 to 2027 [8].

Core Viewpoint - The company, Hualan Biological Engineering Inc., has released its first quarter report for 2025, ensuring the accuracy and completeness of the financial information disclosed, with no significant omissions or misleading statements [1][2]. Financial Data Summary - The first quarter report has not been audited [3][7]. - The company does not require retrospective adjustments or restatements of previous accounting data [3]. - Non-recurring gains and losses include a refund of handling fees [3]. - The company confirms that there are no instances of classifying non-recurring gains and losses as recurring [3]. Shareholder Information - As of the reporting period, the total number of ordinary shareholders is not disclosed, but the company holds 6,027,467 shares in a repurchase account, representing 1.00% of total shares, ranking fifth among the top ten shareholders [5].

面对每天上千份上市公司公告该看哪些？重大事项公告动辄几十页几百页重点是啥？公告里 一堆专业术语不知道算利好还是利空？请看智通财经公司新闻部《速读公告》栏目，我们派 驻全国的记者们将于公告当晚为您带来准确、快速、专业的解读。 智通财经4月27日讯（记者 卢阿峰）今年Q1，国内血液制品上市公司普遍业绩下降，但华兰生物 （002007.SZ）仍然交出了一份较好的成绩单。 公司今日晚间发布公告，今年Q1，公司实现营业收入8.68亿元，同比增长10.2%；归属于上市公司股东 的净利润3.13亿元，同比增长19.62%；扣除非经常性损益的净利润3亿元，同比增长35.35%。 公司提供的资料显示，作为业绩的核心支柱，华兰生物血液制品核心产品的批签发量稳居行业前列。 Q1血液制品业务实现营收8.43亿元，同比增长11.98%；净利润为2.91亿元，同比增长23.47%。 疫苗业务方面，由于受季节性因素制约，流感疫苗销售尚未实现大规模放量。公告显示，华兰疫苗 （301207.SZ）Q1实现营收2428万元，同比下降29.05%；归母净利润3278万元，同比下降15.06%；扣非 净利润1541.58万元，同比增长8.89%。随 ...

Core Viewpoint - Hualan Biological's Q1 2025 financial report shows strong growth driven by its "blood products + vaccines + recombinant protein drugs" strategy, with significant increases in revenue and net profit compared to the previous year [1][2]. Financial Performance - The company achieved a revenue of 868 million yuan, a year-on-year increase of 10.2% [1]. - The net profit attributable to shareholders was 313 million yuan, reflecting a growth of 19.62% year-on-year [1]. - The non-recurring net profit reached 300 million yuan, up 35.35% from the same period last year [1]. - Blood products business generated revenue of 843 million yuan, a growth of 11.98% year-on-year, with a net profit of 291 million yuan, increasing by 23.47% [1]. Product Performance - Hualan Biological maintains a leading market share in domestic blood products, with core product batch approvals remaining among the top in the industry [2]. - The vaccine segment is expected to see growth in Q2 as flu vaccine sales ramp up following seasonal factors [2]. - The new product Bevacizumab began sales in Q1 2025, with expectations for increased sales in Q2, potentially creating a new growth driver [2]. Research and Development - The company invested 66.46 million yuan in R&D, accounting for 7.66% of its revenue, indicating a commitment to biopharmaceutical innovation [2]. - Hualan Biological's plasma collection efforts have led to a record high collection volume of 1586.37 tons in 2024, an increase of 18.18% year-on-year [2]. Strategic Outlook - The Q1 performance validates the effectiveness of the company's three-pronged strategy and demonstrates resilience and robust growth in core business areas [2]. - Future growth is anticipated as domestic vaccine demand recovers and the blood products industry consolidates, with Bevacizumab expected to capture a larger market share in a market projected to reach hundreds of billions [2].