武汉明德生物科技股份有限公司 2025 年半年度报告全文 武汉明德生物科技股份有限公司 2025 年半年度报告 2025 年 8 月 1 武汉明德生物科技股份有限公司 2025 年半年度报告全文 第一节 重要提示、目录和释义 公司董事会、监事会及董事、监事、高级管理人员保证年度报告内容的 真实、准确、完整，不存在虚假记载、误导性陈述或重大遗漏，并承担个别 和连带的法律责任。 公司负责人陈莉莉、主管会计工作负责人王锐及会计机构负责人（会计 主管人员）黎朝辉声明：保证本年度报告中财务报告的真实、准确、完整。 所有董事均已出席了审议本报告的董事会会议。 公司在本报告"第三节 管理层讨论与分析"之"十、公司面临的风险和 应对措施"部分详细描述了未来将面临的主要风险及应对措施，敬请广大投 资者认真阅读相关内容，注意投资风险。 公司计划不派发现金红利，不送红股，不以公积金转增股本。 2 | | | 武汉明德生物科技股份有限公司 2025 年半年度报告全文 备查文件目录 一、载有法定代表人签名的 2025 年半年度报告文本。 二、载有公司法定代表人、主管会计工作负责人、会计机构负责人签名并盖章的财务报告文本。 三、报告期内 ...

Company Overview - Mingde Biological Technology Co., Ltd. specializes in the research, production, sales, and service of in vitro diagnostic reagents and instruments, as well as information solutions for critical care and third-party medical testing services [1] - The company's main products include in vitro diagnostic reagents and instruments, critical care information solutions, and third-party medical testing services [1] Financial Performance - As of the first quarter of 2025, the company reported a revenue of 69.96 million yuan, representing a year-on-year increase of 14.76% [1] - The net profit for the same period was -3.66 million yuan, showing a year-on-year decline of 111.43% [1] - The sales gross margin stood at 16.37% [1] Market Position - The company's current stock price is 21.53 yuan, with a PE ratio of 129.01, significantly higher than the industry average of 55.91 and the industry median of 40.36 [2] - Mingde Biological's total market capitalization is 5.006 billion yuan [1][2] - As of the first quarter of 2025, there are 2 institutional investors holding shares in the company, with a total holding of 123,100 shares valued at 0.02 million yuan [1]

Company Overview - Mingde Biological's stock price is reported at 20.97 yuan, down 0.11 yuan from the previous trading day, representing a decline of 0.52% [1] - The stock reached a high of 21.00 yuan and a low of 20.76 yuan during the trading session, with a trading volume of 26,255 hands and a transaction amount of 55 million yuan [1] Industry Information - The company operates in the medical device industry, focusing on the research, development, production, and sales of in vitro diagnostic reagents and related instruments [1] - Its product range includes testing for infectious diseases, cardiovascular diseases, kidney diseases, and diabetes among other areas [1] Shareholder and Fund Flow Data - As of August 8, 2025, the total number of shareholders for Mingde Biological is reported to be 24,532 [1] - On August 20, the net outflow of main funds was 1.3974 million yuan, with a cumulative net outflow of 12.1727 million yuan over the past five trading days [1]

参考上交所《上市公司治理准则》、港交所《环境、社会及管治守则》等文件，搜狐财经迭代完善各行 业ESG测评体系标准，并以最新标准为依托，以2024年公司ESG报告为主要数据来源，对公司环境资 源、社会责任及公司管治进行了评价。 编者按：ESG年报解读为搜狐财经及价值公司100联合发起的针对各公司ESG报告披露情况的解读专 栏。 本文为"明德生物"篇。 网 资料来源：明德生物官 研究员 | 张子豪 荧光PCR技术赋能检测方案，明德生物体外诊断创新提速 近期，基孔肯雅病毒在中国呈现输入性病例引发局部传播、防控压力持续的态势，主要集中在华南地 区。病毒主要通过埃及伊蚊和白纹伊蚊叮咬传播。 8月12日，明德生物发布了基孔肯雅病毒及蚊媒病原体核酸检测解决方案，采用荧光PCR方法，灵敏度 可达50至200拷贝/毫升，最快1小时内生成检测结果。且该方案已在湖北省内及我国西南地区的疾控中 心与医院中投用。此消息被看作是公司在体外诊断业务产品创新层面的积极动态。 明德生物的基孔肯雅病毒核酸检测解决方案对该病的防控具有快速诊断、精准溯源、降低传播风险的核 心作用，同时也体现了该公司在在技术投入、团队建设、专利布局及产品转化等方面的 ...

8月15日，明德生物今日收盘20.77元，下跌1.05%，滚动市盈率PE（当前股价与前四季度每股收益总和 的比值）达到124.46倍，总市值48.29亿元。 从行业市盈率排名来看，公司所处的医疗器械行业市盈率平均56.58倍，行业中值39.97倍，明德生物排 名第108位。 资金流向方面，8月15日，明德生物主力资金净流出1145.22万元，近5日总体呈流出状态，5日共流出 4145.34万元。 武汉明德生物科技股份有限公司的主营业务是体外诊断试剂和诊断仪器的研发、生产、销售和服务。公 司的主要产品是体外诊断试剂和仪器、急危重症信息化解决方案、第三方医学检验服务。 最新一期业绩显示，2025年一季报，公司实现营业收入6996.03万元，同比14.76%；净利润-3662988.06 元，同比-111.43%，销售毛利率16.37%。 序号股票简称PE(TTM)PE(静)市净率总市值(元)13明德生物124.4664.810.8348.29亿行业平均 56.5852.305.00119.53亿行业中值39.9739.072.9157.03亿1九安医疗11.3611.490.89191.70亿2英科医疗 15.6 ...

Core Viewpoint - Mingde Biological's stock closed at 20.99 yuan, down 2.01%, with a rolling PE ratio of 125.77 times, indicating a significant premium compared to the industry average [1] Company Summary - Mingde Biological focuses on the research, production, sales, and service of in vitro diagnostic reagents and instruments, as well as solutions for critical care information and third-party medical testing services [1] - For Q1 2025, the company reported revenue of 69.96 million yuan, a year-on-year increase of 14.76%, but a net loss of approximately 3.66 million yuan, reflecting a year-on-year decline of 111.43%, with a gross profit margin of 16.37% [1] Industry Summary - The average PE ratio for the medical device industry is 55.76 times, with a median of 39.14 times, positioning Mingde Biological at the 108th rank within the industry [1] - As of Q1 2025, there are 2 institutional investors holding shares in Mingde Biological, with a total holding of 123,100 shares valued at 0.02 million yuan [1]

Group 1 - Multiple listed companies are developing detection solutions for Chikungunya virus, including Kingmed Diagnostics, Wanfu Biology, and Shengxiang Biology [1][2] - Kingmed Diagnostics has established a comprehensive platform for serological, fluorescent PCR, and sequencing tests to accurately identify the Chikungunya virus, aiding in clinical diagnosis [1] - Wanfu Biology has responded to the recent guidelines from the National Disease Control Bureau by developing several detection products that create a closed-loop system for rapid screening, precise detection, and monitoring [1] - Shengxiang Biology has introduced a dual-platform solution combining rapid nucleic acid testing and sequencing for precise tracing, with a detection time of 25 to 45 minutes and high sensitivity [1] Group 2 - According to a report by Everbright Securities, several domestic listed companies, including Da'an Gene, Wanfu Biology, Shengxiang Biology, Zhijiang Biology, Shuoshi Biology, Mingde Biology, and Rendu Biology, have launched Chikungunya virus detection solutions [2]

Core Viewpoint - The article discusses the outbreak of Chikungunya fever in China and globally, highlighting the urgent need for effective detection and prevention measures due to the lack of specific treatments and vaccines [2][3]. Group 1: Current Situation - As of July 23, 2025, Foshan reported a total of 3,645 confirmed cases of Chikungunya fever, with the Shunde District accounting for 3,317 cases, an increase of 383 cases from the previous day [2]. - The World Health Organization (WHO) has warned that 119 countries and regions are experiencing virus transmission, with approximately 5.5 million people at risk of infection, potentially straining healthcare systems [2]. Group 2: Prevention and Control - There are currently no specific drugs or vaccines for Chikungunya fever; the primary prevention strategy is mosquito control, including eliminating breeding sites and using personal protective measures [3]. - The clinical features of Chikungunya fever include acute fever, severe joint pain, and rash, with higher risks for children, the elderly, and immunocompromised individuals [3]. Group 3: Diagnostic Methods - Common diagnostic methods for Chikungunya fever include serological testing, nucleic acid testing, and virus isolation, with specific timelines for sample collection to ensure accurate results [4]. - Currently, there are no approved test kits for Chikungunya fever in China, which poses a challenge for timely diagnosis [4]. Group 4: Market Opportunities - Several domestic companies, including DaAn Gene, Wanfu Biology, and Shengxiang Biology, are developing Chikungunya fever detection solutions based on PCR methodologies, with others exploring high-throughput sequencing and antigen-antibody detection methods [5]. - The ongoing outbreak is expected to accelerate the accumulation of clinical data for these detection products, potentially speeding up their approval and market entry [5].

Investment Rating - The report maintains an "Overweight" rating for the pharmaceutical and biotechnology sector [4]. Core Insights - The number of confirmed cases of Chikungunya fever is rapidly increasing, with 3,645 cases reported in Foshan as of July 23, 2025, including a daily increase of 383 cases in Shunde District [1]. - The World Health Organization (WHO) has warned that 119 countries and regions are at risk of virus transmission, with approximately 5.5 million people facing infection risk [1]. - There are currently no specific drugs or vaccines available for Chikungunya fever, making mosquito control the primary prevention strategy [2]. - Multiple companies have launched testing solutions for Chikungunya fever, and the approval of these products is expected to accelerate [3]. Summary by Sections Industry Overview - Chikungunya fever is caused by the Chikungunya virus (CHIKV) and primarily transmitted by Aedes mosquitoes, with symptoms including acute fever and severe joint pain [2]. - The absence of effective treatment and vaccines necessitates supportive care and preventive measures such as mosquito control [2]. Testing Solutions - Common testing methods for Chikungunya fever include serological testing, nucleic acid testing, and virus isolation, but no test kits have been approved for sale in China [2]. - Companies like DaAn Gene, Wanfu Biology, and others have developed PCR-based testing solutions, while others are exploring high-throughput sequencing methods [3]. Investment Opportunities - The report suggests focusing on companies that have developed Chikungunya testing solutions, including DaAn Gene, Wanfu Biology, and others [3].

Core Viewpoint - The epidemic of Chikungunya fever in Guangdong Province remains at a high plateau, indicating a severe situation that requires attention [1]. Summary by Sections Epidemic Situation - As of July 22, 2025, Shunde District in Foshan City reported a total of 2,934 confirmed cases of Chikungunya fever, with a significant increase of 463 cases in just one day [4][5]. - The first report of the epidemic in Shunde was on July 15, 2025, with 478 confirmed cases, showing an increase of over 2,000 cases in just over a week [4]. - The World Health Organization (WHO) reported that 119 countries and regions have identified Chikungunya virus transmission, with approximately 5.5 million people at risk globally, potentially leading to widespread outbreaks [4][5]. Companies Involved in Prevention and Detection - **Runben Co., Ltd. (润本股份)**: A leading domestic company in mosquito repellent products, with a revenue of 440 million yuan in 2024, showing a year-on-year growth of 35.4% and a gross margin of 54.2% [7]. - **Rainbow Group (彩虹集团)**: A well-known pest control company in China, offering a full range of mosquito repellent products that play a crucial role in controlling Chikungunya fever [8]. - **Shanghai Jahwa (上海家化)**: The "Liushen" brand is the top brand in China for mosquito repellent flower water, holding significant brand influence in mosquito prevention and personal care [9]. - **Longyun Group (朗云集团)**: A Hong Kong-listed company that has maintained the number one market share in pest control products for ten consecutive years, with notable products performing well during the epidemic [10]. - **Kangzhi Pharmaceutical (康芝药业)**: Offers a full range of baby and child health protection products, including disinfectants and mosquito repellents, demonstrating expertise in child health protection [11]. - **Shuoshi Gene (硕世纪录物)**: Utilizes gene sequencing technology for Chikungunya fever testing, providing precise diagnostic support for epidemic prevention [12]. - **Da'an Gene (达安基因)**: Provides nucleic acid testing kits for Chikungunya virus, leveraging extensive experience in molecular diagnostics [13]. - **Huiyu Medical (会域医学)**: A leading medical testing institution in China, employing advanced technology for accurate diagnosis of Chikungunya fever [14]. - **Wansheng Biology (万学生物)**: Offers rapid testing solutions for Chikungunya virus, focusing on point-of-care testing [16]. - **Nuo Weisha (诺唯莎)**: Combines molecular design with various heat-start technologies to enhance detection efficiency for mosquito-borne viruses [17].