Core Points - The Shenzhen-Hong Kong Medical Index (983035) closed at 4494.42 points, up 0.15%, with a trading volume of 7.52 billion yuan and a turnover rate of 0.75% [1] - Among the index constituents, 32 stocks rose while 24 fell, with Medical Pulse leading the gainers at 3.65% and Health Road leading the decliners at 3.41% [1] Index Constituents Summary - The top ten constituents of the Shenzhen-Hong Kong Medical Index include: - Mindray Medical (14.56% weight, latest price 196.30 yuan, market cap 238 billion yuan, up 1.50%) [1] - Yier Eye Hospital (11.62% weight, latest price 11.40 yuan, market cap 106.31 billion yuan, down 0.26%) [1] - Lejin Medical (4.85% weight, latest price 15.87 yuan, market cap 29.26 billion yuan, up 0.13%) [1] - Aimeike (4.80% weight, latest price 146.26 yuan, market cap 44.26 billion yuan, up 0.83%) [1] - Yuyue Medical (4.66% weight, latest price 35.70 yuan, market cap 35.79 billion yuan, down 0.67%) [1] - Yingke Medical (3.64% weight, latest price 41.53 yuan, market cap 27.21 billion yuan, up 1.94%) [1] - Furuide (3.59% weight, latest price 67.08 yuan, market cap 17.78 billion yuan, up 1.36%) [1] - Meinian Health (3.58% weight, latest price 5.28 yuan, market cap 20.67 billion yuan, down 1.68%) [1] - Sinopharm (3.35% weight, latest price 18.42 yuan, market cap 57.48 billion yuan, down 0.69%) [1] - Ping An Good Doctor (2.63% weight, latest price 13.66 yuan, market cap 29.52 billion yuan, down 1.83%) [1] Capital Flow Analysis - The net outflow of main funds from the index constituents totaled 58.83 million yuan, while retail investors saw a net inflow of 78.07 million yuan [1] - Specific stock capital flows include: - Aimeike: Main fund net inflow of 46.99 million yuan, retail net outflow of 30.07 million yuan [2] - Mindray Medical: Main fund net inflow of 33.08 million yuan, retail net outflow of 17.11 million yuan [2] - Furuide: Main fund net inflow of 13.68 million yuan, retail net outflow of 19.08 million yuan [2] Recent Adjustments - The Shenzhen-Hong Kong Medical Index has undergone adjustments in the last 10 days, with one new stock added [2]

Market Overview - The medical services sector declined by 0.47% on November 14, with the digital human sector leading the drop [1] - The Shanghai Composite Index closed at 3990.49, down 0.97%, while the Shenzhen Component Index closed at 13216.03, down 1.93% [1] Stock Performance - Notable declines in individual stocks include: - Digital Human: closed at 17.28, down 4.85% with a trading volume of 80,400 shares and a turnover of 1.411 million [1] - Haoyuan Pharmaceutical: closed at 77.20, down 3.54% with a trading volume of 30,800 shares and a turnover of 2.4212 million [1] - Yinos: closed at 48.69, down 2.62% with a trading volume of 14,300 shares and a turnover of 7132.217 [1] - Other notable declines include Taige Pharmaceutical, MediX, and WuXi AppTec, all showing declines between 1.28% and 2.08% [1] Capital Flow - The medical services sector experienced a net outflow of 238 million yuan from institutional investors, while retail investors saw a net inflow of 181 million yuan [3] - Notable capital flows for specific stocks include: - Ruizhi Pharmaceutical: net inflow of 38.93 million yuan from institutional investors, but net outflows from retail and speculative investors [3] - Chengda Pharmaceutical: net inflow of 37.96 million yuan from institutional investors, with significant outflows from speculative investors [3] - Other stocks like Sanbo Brain Science and Jinyu Medical also showed varying net inflows and outflows among different investor types [3]

Core Insights - The brain engineering sector is leading the market with a rise of 1.05% [1] Company Performance - Aipeng Medical saw a significant increase of 7.51% [1] - Innovation Medical experienced a rise of 4.41% [1] - Century Huatong increased by 3.41% [1] - Chengyitong, Xiangyu Medical, and Sanbo Brain Science all rose by over 2% [1]

北京市中伦律师事务所 关于三博脑科医院管理集团股份有限公司 2025 年第二次临时股东会的 法律意见 二〇二五年十一月 北京 • 上海 • 深圳 • 广州 • 武汉 • 成都 • 重庆 • 青岛 • 杭州 • 南京 • 海口 • 东京 • 香港 • 伦敦 • 纽约 • 洛杉矶 • 旧金山 • 阿拉木图 Beijing • Shanghai • Shenzhen • Guangzhou • Wuhan • Chengdu • Chongqing • Qingdao • Hangzhou • Nanjing • Haikou • Tokyo • Hong Kong • London • New York • Los Angeles • San Francisco • Almaty 北京市中伦律师事务所 关于三博脑科医院管理集团股份有限公司 2025 年第二次临时股东会的 法律意见 致：三博脑科医院管理集团股份有限公司 北京市中伦律师事务所（以下简称"本所"）接受三博脑科医院管理集团股份 有限公司（以下简称"公司"）委托，指派本所律师列席公司 2025 年第二次临时 股东会（以下简称"本次股东会"），并出具本法律意 ...

证券代码：301293 证券简称：三博脑科 公告编号：2025-046 三博脑科医院管理集团股份有限公司 2025 年第二次临时股东会决议公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 特别提示： 1、本次股东会未出现否决议案的情形； 2、本次股东会未涉及变更以往股东会已通过的决议。 一、会议召开和出席情况 （一）会议召开情况 1、股东会召集人：公司董事会。 2、会议召开的合法、合规性：本次股东会的召开符合有关法律、行政法规、 部门规章、规范性文件及《公司章程》的规定。 3、会议召开时间： 1 权股份总数的 37.3230％。其中：通过现场投票的股东 3 人，代表股份 21,948,003 股，占公司有表决权股份总数的 10.8124％。通过网络投票的股东 288 人，代表 股份 53,813,928 股，占公司有表决权股份总数的 26.5107％。 （1）现场会议时间：2025 年 11 月 12 日下午 15:30 （2）网络投票时间：通过深圳证券交易所交易系统进行网络投票的具体时 间为：2025 年 11 月 12 日上午 9:15-9:25、9: ...

Group 1 - The core point of the news is that Shanghai Ladder Medical Technology Co., Ltd. has developed an "implantable wireless brain-machine interface system" which has entered the special review process for innovative medical devices by the National Medical Products Administration (NMPA) in China, marking a significant step in the commercialization of this cutting-edge technology in the country [1] - This product is the first invasive brain-machine interface to enter the "green channel" for medical devices in China, indicating a transition from clinical validation to market access [1] Group 2 - Following this news, A-share market stocks related to brain-machine interfaces have shown strong performance, with Aipeng Medical rising nearly 12%, Century Huatong and Innovation Medical increasing over 7%, and Botuo Bio up over 5% [2] - Other companies in the sector, such as Xiangyu Medical, Sanbo Neuroscience, Saili Medical, Dinake, Taihe Technology, and Chengyitong, have also seen their stock prices rise by over 3% [2]

Core Viewpoint - The A-share market is experiencing a surge in brain-computer interface concept stocks, driven by the approval of a domestically developed implantable wireless brain-computer interface system entering the special review process by the National Medical Products Administration of China, marking a significant step in the commercialization of this technology in China [1] Group 1: Stock Performance - Aipeng Medical saw a nearly 12% increase in stock price, with a total market value of 40.03 billion and a year-to-date increase of 80.63% [2] - Century Huatong and Innovative Medical both rose over 7%, with market values of 141.1 billion and 10.5 billion respectively, and year-to-date increases of 269.65% and 198.87% [2] - Botao Biological increased by over 5%, with a market value of 6.62 billion and a year-to-date increase of 95.06% [2] - Xiangyu Medical rose over 4%, with a market value of 8.33 billion and a year-to-date increase of 78.19% [2] - Other notable stocks include Sanbo Brain Science, Saily Medical, Dineike, Taihe Technology, and Chengyi Tong, all showing increases of over 3% [1][2] Group 2: Industry Development - The implantable wireless brain-computer interface system developed by Shanghai Ladder Medical Technology Co., Ltd. is the first invasive brain-computer interface product to enter the "green channel" for innovative medical devices in China, indicating a key advancement from clinical validation to market access in this cutting-edge technology field [1]

Core Insights - The CSI Medical Index (399989) closed at 7188.73 points, down 0.49%, with a trading volume of 15.495 billion yuan and a turnover rate of 1.31% [1] - Among the index constituents, 20 stocks rose while 29 stocks fell, with Furuide (福瑞股份) leading the gainers at 4.41% and Sanbo Brain Science (三博脑科) leading the decliners at 5.29% [1] Index Performance - The CSI Medical Index's top ten constituents include: - WuXi AppTec (药明康德) with a weight of 13.85% and a latest price of 94.84 yuan, down 0.89% [1] - Mindray Medical (迈瑞医疗) with a weight of 8.24% and a latest price of 205.79 yuan, down 0.27% [1] - United Imaging Healthcare (联影医疗) with a weight of 7.95% and a latest price of 137.66 yuan, down 0.10% [1] - Aier Eye Hospital (爱尔眼科) with a weight of 6.56% and a latest price of 12.06 yuan, unchanged [1] - Tigermed (泰格医药) with a weight of 3.55% and a latest price of 58.32 yuan, down 0.63% [1] - Kanglong Chemical (康龙化成) with a weight of 3.41% and a latest price of 31.67 yuan, down 1.80% [1] - Aimeike (爱美客) with a weight of 2.78% and a latest price of 149.16 yuan, down 1.87% [1] - New Industry (新产业) with a weight of 2.75% and a latest price of 62.34 yuan, up 0.58% [1] - Lepu Medical (乐普医疗) with a weight of 2.74% and a latest price of 16.74 yuan, down 3.07% [1] - Huatai Medical (惠泰医疗) with a weight of 2.68% and a latest price of 283.50 yuan, down 0.65% [1] Capital Flow - The net outflow of main funds from the CSI Medical Index constituents totaled 724 million yuan, while retail investors saw a net inflow of 604 million yuan [1] - Notable capital flows include: - Furuide (福瑞股份) with a net inflow of 96.5164 million yuan from main funds [2] - Mindray Medical (迈瑞医疗) with a net outflow of 90.3162 million yuan from speculative funds [2] - Yuyue Medical (鱼跃医疗) with a net inflow of 81.3628 million yuan from main funds [2]

Market Overview - The medical services sector experienced a decline of 0.21% on November 7, with Sanbo Brain Science leading the drop [1] - The Shanghai Composite Index closed at 3997.56, down 0.25%, while the Shenzhen Component Index closed at 13404.06, down 0.36% [1] Stock Performance - Notable gainers in the medical services sector included: - Yingkang Life: closed at 10.64, up 1.04% with a trading volume of 67,000 shares and a turnover of 71.37 million yuan [1] - Lanwei Medical: closed at 9.90, up 0.92% with a trading volume of 41,900 shares and a turnover of 41.39 million yuan [1] - Aoyang Health: closed at 4.51, up 0.89% with a trading volume of 333,700 shares and a turnover of 151 million yuan [1] - Major decliners included: - Sanbo Brain Science: closed at 59.07, down 5.29% with a trading volume of 136,500 shares and a turnover of 812 million yuan [2] - Chuangxin Medical: closed at 23.13, down 4.62% with a trading volume of 567,100 shares and a turnover of 1.316 billion yuan [2] - Shuyuan New Drug: closed at 32.49, down 3.30% with a trading volume of 146,800 shares and a turnover of 482 million yuan [2] Capital Flow - The medical services sector saw a net outflow of 845 million yuan from institutional investors, while retail investors contributed a net inflow of 720 million yuan [2] - Key stocks with significant capital flow included: - Hai Te Biological: net inflow of 20.28 million yuan from institutional investors [3] - Aoyang Health: net inflow of 14.05 million yuan from institutional investors [3] - Yingkang Life: net inflow of 5.65 million yuan from institutional investors [3]

Core Viewpoint - Sanbo Brain Science (301293) stated on November 6 that it will disclose shareholder information in its regular reports according to information disclosure regulations [1] Group 1 - The company will provide details about the number of shareholders in its periodic reports [1]