报名：首届全球眼科大会 | 参会须知 报名：首届全球骨科大会 | 议程更新 报名：首届全球心血管大会 | 奖项申报 合作伙伴征集：2025全球手术机器人大会 2025年4月15日， 强生 Johnson & Johnson (NYSE: JNJ) 受第一季度业绩和关税影响， 股价略有下跌。15日 下午的交易中，强生股价下跌近 1%，至 每股 153.21 美元。 在公司第一季度财报电话会议上，首席财务官Joseph Wolk 首次向 CNBC 概述此次关税成本预计达到4亿美元（约合30亿人民币），并解释了特朗普政府 关税政策对公司可能产生哪些影响。 # 财报亮点 | | | Q1 | | | --- | --- | --- | --- | | ($ in Millions, except EPS) | 2025 | 2024 | % Change | | Reported Sales | $21,893 | $21,383 | 2.4% | | Net Earnings | $10,999 | $3,255 | 237.9% | | EPS (diluted) | $4.54 | $1.34 | 238.8% ...

Regulatory Developments - The National Medical Products Administration reported four cases of illegal online sales of medical devices, emphasizing a "zero tolerance" regulatory attitude to ensure safety in medical device usage [2] - Companies involved include Jiangyin Tianyu Medical Device Co., Yiwu Shenghe Medical Device Co., Shanghai Yile Warehouse Medical Device Co., and Hefei Baohua Design Studio, all of which failed to comply with regulatory requirements [2] Industry Advancements - Hangzhou is accelerating the development of medical artificial intelligence applications, aiming to establish a national AI (medical) application pilot base and create intelligent medical entities focused on various health management areas [3] - The city plans to build digital health innovation laboratories to advance key technologies in medical AI [3] Company Announcements - Leksin Medical received a medical device registration certificate for its wrist-type electronic blood pressure monitor from the Guangdong Provincial Drug Administration [5] - David Medical's wholly-owned subsidiary, Ningbo Yongxing Medical Instruments Co., obtained a medical device registration certificate for a linear cutting stapler used in various surgical procedures [6] - Warner Pharmaceuticals announced the approval of its drug registration certificate for the injection of methoxamine hydrochloride, used for treating acute hypotension during spinal anesthesia [7] Financial Reports - Guobang Pharmaceutical reported a revenue of 1.44 billion yuan for Q1 2025, a year-on-year increase of 7.57%, with a net profit of 215 million yuan, up 8.17% [9] - Johnson & Johnson's Q1 sales reached 21.89 billion dollars, with an annual sales forecast of 91 to 91.8 billion dollars and adjusted earnings per share projected between 10.50 and 10.70 dollars [10] Market Movements - In Hong Kong, InnoCare's stock surged by 130% on its first trading day [12] - Darentang announced plans to transfer a 12% stake in China-US Tianjin Schering Pharmaceutical Co., with estimated investment income of approximately 1.54 billion yuan from the transaction [13] - Nanjing Noling Biotechnology completed a C-round financing of several hundred million yuan, led by Dingxin Capital [14] Collaborative Initiatives - Berry Genomics' subsidiary signed a project cooperation framework agreement with Beijing Children's Hospital to promote clinical transformation and commercialization of research outcomes related to newborn screening technologies [16] - Bangyan Technology plans to officially launch its AI Agent product this year, aimed at assisting digital transformation in the healthcare sector [17] Personnel Changes - Bell Bio's financial officer, Zhao Baozhen, resigned for personal reasons but will continue to serve as the board secretary [19]

Group 1 - Proactive provides fast, accessible, informative, and actionable business and finance news content to a global investment audience [2] - The news team covers medium and small-cap markets, as well as blue-chip companies, commodities, and broader investment stories [3] - Proactive has bureaus and studios in key finance and investing hubs including London, New York, Toronto, Vancouver, Sydney, and Perth [2][3] Group 2 - The company is focused on sectors such as biotech and pharma, mining and natural resources, battery metals, oil and gas, crypto, and emerging digital and EV technologies [3] - Proactive adopts technology to enhance workflows and improve content production [4] - Automation and software tools, including generative AI, are used, but all content is edited and authored by humans [5]

Financial Performance - Worldwide sales for Q1 2025 reached $219 billion, a 24% increase compared to Q1 2024, with operational sales growth of 42%[52] - Adjusted earnings for Q1 2025 were $67 billion, resulting in adjusted EPS of $277, a 22% increase[54] - The company is increasing its 2025 operational sales guidance midpoint by $07 billion to 38% due to the Intra-Cellular Therapies (ITCI) acquisition[72] Innovative Medicine - Innovative Medicine achieved 42% operational sales growth in Q1 2025, driven by key brands growing in double digits[15] - Oncology sales reached $5678 million, demonstrating strong growth[57] - TREMFYA showed superiority versus STELARA in endoscopic endpoints in Crohn's disease, with 34% of patients achieving deep remission at 1 year[42] MedTech - MedTech reported 41% operational sales growth in Q1 2025, with strong performance across Abiomed, Shockwave, Vision, and Wound Closure[17, 59] - Cardiovascular sales increased by 177% operationally[60] - Orthopaedics experienced a (31)% operational decrease, impacted by one-time events[62] Pipeline and Milestones - RYBREVANT plus LAZCLUZE demonstrated a significant overall survival benefit in first-line EGFR-mutated non-small cell lung cancer, with a projected median OS improvement of more than 1 year[38] - Icotrokinra showed potential in treating plaque psoriasis, with 46% of patients achieving completely clear skin (IGA 0) and 75% among adolescents[49] - The company anticipates several milestones in 2025, including potential approvals for nipocalimab in gMG, RYBREVANT Sub-Q in NSCLC, and TREMFYA Sub-Q in UC[75]

Core Insights - Johnson & Johnson (J&J) reported first-quarter 2025 earnings of $2.77 per share, exceeding the Zacks Consensus Estimate of $2.57, with a year-over-year increase of 2.2% [1] - Total sales reached $21.89 billion, slightly above the Zacks Consensus Estimate of $21.62 billion, reflecting a 2.4% increase from the previous year [2] - The Innovative Medicines segment showed strong performance, while the MedTech segment missed sales estimates [4][15] Financial Performance - Adjusted earnings, excluding special items, were reported at $4.54 per share, a significant increase of 238.8% year over year [1] - Domestic sales rose 5.9% to $12.3 billion, while international sales declined 1.8% to $9.59 billion [3] - The company raised its 2025 sales guidance to a range of $91.0 billion to $91.8 billion, reflecting an increase from the previous range of $89.2 billion to $90.0 billion [17] Segment Performance - Innovative Medicines segment sales increased by 2.3% year over year to $13.87 billion, outperforming the Zacks Consensus Estimate of $13.46 billion [5] - Key products driving growth included Darzalex, Tremfya, and Erleada, while Stelara sales declined by 33.7% due to biosimilar competition [6][8] - MedTech segment sales were reported at $8.02 billion, up 2.5% year over year, but missed estimates [15] Market Dynamics - The decline in Stelara sales was attributed to the launch of biosimilars, with competition expected to increase in 2025 [9] - The MedTech business faced challenges in the Asia Pacific region, particularly in China, due to government cost containment efforts [16] - J&J's stock has seen a 7.6% increase year-to-date, contrasting with a 6.0% decrease in the industry [22] Future Outlook - The company anticipates growth in the Innovative Medicines segment driven by key products and new drug launches [23] - Despite the positive outlook, challenges such as the Stelara patent cliff and ongoing legal issues related to talc lawsuits may pose significant headwinds [24]

Core Insights - Johnson & Johnson reported $21.89 billion in revenue for Q1 2025, a year-over-year increase of 2.4% and an EPS of $2.77, up from $2.71 a year ago, exceeding Zacks Consensus Estimates for both revenue and EPS [1] Financial Performance - Revenue of $21.89 billion surpassed the Zacks Consensus Estimate of $21.62 billion, resulting in a surprise of +1.26% [1] - EPS of $2.77 exceeded the consensus estimate of $2.57, delivering a surprise of +7.78% [1] Key Metrics - Organic Sales Growth was reported at 4.2%, higher than the estimated 3.4% [4] - Sales in Innovative Medicine for Oncology (CARVYKTI) reached $369 million, significantly above the estimate of $341.85 million, marking a year-over-year increase of +135% [4] - Sales in Innovative Medicine for Neuroscience (SPRAVATO) were $320 million, slightly above the estimate of $319.68 million, with a year-over-year increase of +42.2% [4] - Total MedTech sales were $8.02 billion, below the estimate of $8.14 billion, reflecting a +2.5% change year-over-year [4] - Sales in MedTech for Cardiovascular (ABIOMED) were $420 million, exceeding the estimate of $400.66 million, with a year-over-year increase of +13.2% [4] Stock Performance - Johnson & Johnson shares returned -5.2% over the past month, compared to the Zacks S&P 500 composite's -3.9% change, indicating potential underperformance in the near term with a Zacks Rank 4 (Sell) [3]

Group 1 - Proactive provides fast, accessible, informative, and actionable business and finance news content to a global investment audience [2] - The news team covers medium and small-cap markets, as well as blue-chip companies, commodities, and broader investment stories [3] - Proactive's content includes insights across various sectors such as biotech, pharma, mining, natural resources, battery metals, oil and gas, crypto, and emerging technologies [3] Group 2 - Proactive is committed to adopting technology to enhance workflows and improve content production [4] - The company utilizes automation and software tools, including generative AI, while ensuring all content is edited and authored by humans [5]

Financial Data and Key Metrics Changes - In Q1 2025, the company reported worldwide sales of $21.9 billion, reflecting a 4.2% increase despite a 470 basis point headwind from Stelara [25][27] - Net earnings for the quarter were $11 billion, with diluted earnings per share at $4.54, significantly up from $1.34 a year ago, primarily due to a $7 billion reversal related to the talc settlement proposal [26][40] - Adjusted net earnings were $6.7 billion, with adjusted diluted earnings per share at $2.77, representing increases of 1.9% and 2.2% respectively compared to Q1 2024 [26][40] Business Line Data and Key Metrics Changes - Innovative Medicine achieved worldwide sales of $13.9 billion, up 4.2%, with U.S. growth at 6.3% and international growth at 1.5% [27][30] - In Oncology, DARZALEX grew by 22.5%, while PERVICTI saw over 100% growth, driven by share gains and capacity expansion [28][30] - MedTech reported worldwide sales of $8 billion, increasing by 4.1%, with U.S. growth at 5.1% and international growth at 3% [32][33] Market Data and Key Metrics Changes - U.S. sales growth was 5.9%, while international sales growth was 2.1% [25] - The company experienced a positive impact of 90 basis points from acquisitions and divestitures on worldwide growth [25] - MedTech performance was affected by one-time events, particularly in orthopedics, which declined by 3.1% [37] Company Strategy and Development Direction - The company plans to invest over $55 billion in the U.S. over the next four years to enhance manufacturing, R&D, and technology [13][15] - The acquisition of Intra Cellular Therapies is expected to bolster the neuroscience portfolio, with CAPLYTA projected to have over $5 billion in peak year sales potential [16][46] - A restructuring program is being implemented to simplify operations in the surgery business, with an estimated cost of $900 million [44][45] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving 2025 guidance despite challenges from Stelara's biosimilars and Part D redesign [7][76] - The company anticipates higher growth in the second half of the year, particularly in MedTech, as new products gain traction [44][51] - Management highlighted the resilience of the diversified business model in navigating headwinds and delivering on financial commitments [57] Other Important Information - The company increased its dividend for the 63rd consecutive year, reflecting its commitment to returning capital to shareholders [17][46] - The effective tax rate for the quarter was 19.3%, influenced by the reversal of the talc settlement accrual [40] Q&A Session Summary Question: Impact of tariffs on guidance - The company discussed $400 million in tariffs primarily affecting MedTech, with limited price leverage to pass costs to customers [58][60] Question: Gross margins in the quarter - Management noted that gross margins were impacted by the loss of Stelara and Part D redesign, with expectations for improvement moving forward [68][70] Question: Erosion of Stelara due to biosimilars - Management indicated that the impact of Stelara's biosimilars was in line with expectations, with overall business growth remaining strong despite this headwind [74][76] Question: Recession impact on business - Management expressed confidence in the healthcare sector's resilience during economic downturns, noting that elective procedures may be delayed but not abandoned [81][84] Question: Section 232 potential pharma tariffs - Management is analyzing the potential impact of Section 232 tariffs, emphasizing the importance of partnering with the administration to mitigate supply chain vulnerabilities [90]

Core Insights - Johnson & Johnson (JNJ) reported quarterly earnings of $2.77 per share, exceeding the Zacks Consensus Estimate of $2.57 per share, and showing an increase from $2.71 per share a year ago, resulting in an earnings surprise of 7.78% [1] - The company achieved revenues of $21.89 billion for the quarter ended March 2025, surpassing the Zacks Consensus Estimate by 1.26% and up from $21.38 billion year-over-year [2] - Johnson & Johnson has consistently outperformed consensus EPS and revenue estimates over the last four quarters [2] Earnings Outlook - The future stock price movement will largely depend on management's commentary during the earnings call and the sustainability of the recent earnings performance [3] - Current consensus EPS estimate for the upcoming quarter is $2.67 on revenues of $22.61 billion, and for the current fiscal year, it is $10.54 on revenues of $90.22 billion [7] Industry Context - The Large Cap Pharmaceuticals industry, to which Johnson & Johnson belongs, is currently ranked in the top 30% of over 250 Zacks industries, indicating a favorable outlook compared to the bottom 50% [8] - Empirical research suggests a strong correlation between near-term stock movements and trends in earnings estimate revisions, which can be tracked by investors [5] Competitor Insights - Merck (MRK), another company in the same industry, is expected to report quarterly earnings of $2.16 per share, reflecting a year-over-year increase of 4.4%, with revenues anticipated to be $15.48 billion, down 1.9% from the previous year [9][10]

Financial Data and Key Metrics Changes - In Q1 2025, Johnson & Johnson reported worldwide sales of $21.9 billion, reflecting a 4.2% increase year-over-year despite a 470 basis point headwind from Stellara [36][37] - Net earnings for the quarter were $11 billion, with diluted earnings per share at $4.54, significantly up from $1.34 a year ago, primarily due to the reversal of a $7 billion talc settlement proposal [38][39] - Adjusted net earnings were $6.7 billion, with adjusted diluted earnings per share at $2.77, representing increases of 1.9% and 2.2% respectively compared to Q1 2024 [38][39] Business Line Data and Key Metrics Changes - Innovative Medicine achieved worldwide sales of $13.9 billion, up 4.2%, with U.S. growth at 6.3% and international growth at 1.5% [40] - Oncology products like Darzalex grew by 22.5%, while Carvicti saw over 100% growth, achieving sales of $369 million [40][41] - MedTech reported worldwide sales of $8 billion, a 4.1% increase, with U.S. growth at 5.1% and international growth at 3% [46] Market Data and Key Metrics Changes - U.S. sales growth was 5.9%, while international sales growth was 2.1%, positively impacted by acquisitions and divestitures [37] - The MedTech segment faced challenges due to one-time events and competitive pressures, particularly in orthopedics, which declined by 3.1% [50][46] Company Strategy and Development Direction - The company plans to invest over $55 billion in the U.S. over the next four years to enhance manufacturing and R&D capabilities [19][20] - Johnson & Johnson aims to exit non-strategic product lines and optimize select sites to improve growth and profitability, with a restructuring program expected to be completed by 2027 [60][61] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to grow despite challenges from Stellara biosimilars and Part D redesign, highlighting a 4.2% growth across Innovative Medicine [10][102] - The company anticipates higher growth in the second half of 2025, driven by new product launches and a strong pipeline [66][71] Other Important Information - The company announced a 4.8% increase in dividends, marking the 63rd consecutive year of dividend increases [22][64] - Johnson & Johnson reversed a $7 billion reserve related to the talc settlement, which is expected to positively impact capital allocation priorities [65] Q&A Session Summary Question: Impact of tariffs on guidance - Management explained that the $400 million in tariffs primarily affects MedTech and includes various tariffs from Mexico, Canada, and China, with limited price leverage available to mitigate these costs [82][86] Question: Gross margins in the quarter - Management noted that gross margins were impacted by Stellara's decline and Part D redesign, with expectations for improvement moving forward [93][96] Question: Stellara biosimilar erosion - Management confirmed that the impact of Stellara biosimilars was in line with expectations, with overall business growth remaining strong despite this headwind [99][102] Question: Recession impact on business - Management indicated that healthcare has proven to be more recession-proof than other industries, with a focus on monitoring job reports as a precursor to healthcare demand [110][112] Question: Section 232 potential pharma tariffs - Management is analyzing the potential impact of Section 232 tariffs and emphasized the importance of partnering with the administration to mitigate vulnerabilities in the healthcare supply chain [117][120]