Core Viewpoint - Zhaoyan New Drug (06127) has seen its stock price increase by over 60% in the past month, with a current price of HKD 25.92, reflecting a rise of 7.02% as of the latest report [1] Group 1: Stock Performance - The stock price of Zhaoyan New Drug has risen by more than 7% recently, with a trading volume of HKD 203 million [1] - Over the past month, the cumulative increase in stock price is nearly 60% [1] Group 2: Market Insights - Guohai Securities highlights that during the safety evaluation phase, new technology platforms such as large molecules (multi-antibodies, ADC), small nucleic acids, peptides, and cell gene therapies require macaque monkeys for safety testing, indicating a recovery in the domestic innovative drug development environment [1] - The price of macaque monkeys has increased significantly, reaching HKD 140,000 each, leading to a supply-demand imbalance in the market [1] Group 3: Financial Projections - According to estimates from Founder Securities, if the average price of experimental monkeys is set at HKD 84,900 per monkey for 2024 and increases to HKD 140,000 by Q4 2025, the projected fair value increase for Zhaoyan New Drug could be approximately HKD 220 million in 2025, based on a known population of 23,200 monkeys [1]

Core Viewpoint - The price of experimental monkeys, particularly for the 3-5 year old crab-eating macaques, has surged to 140,000 yuan each, indicating a supply-demand imbalance in the market. This trend is expected to benefit companies like Zhaoyan New Drug, which possess valuable resources in this area [1] Company Summary - Zhaoyan New Drug's stock has seen an increase of over 4%, currently trading at 24 Hong Kong dollars with a transaction volume of 108 million Hong Kong dollars [1] - The company has access to high-quality and scarce experimental monkey resources, which contribute to a stable profit base through annual sales of a certain number of monkeys for internal use [1] - In the context of tightening supply of experimental monkeys, Zhaoyan New Drug may gain stronger bargaining power, potentially leading to increased order rates and the ability to charge premium service fees [1] Industry Summary - The supply of experimental monkeys is declining while demand is stabilizing and recovering, driven by new technologies such as small nucleic acids and CAR-T, which require the use of experimental monkeys [1] - The gap between supply and demand for experimental monkeys is widening, leading to an upward trend in monkey prices [1]

Group 1 - The core viewpoint of the article highlights the rising price of experimental monkeys, particularly for the species used in research, which has reached 140,000 yuan each, indicating a supply-demand imbalance in the market [1] - Changjiang Securities reports that the supply of experimental monkeys is decreasing while demand is stabilizing and increasing, particularly due to new technologies like small nucleic acids and CAR-T that require these monkeys, leading to a widening supply-demand gap [1] - The company, Zhaoyan New Drug, possesses valuable and scarce resources of experimental monkeys, which not only contributes to a stable profit base through annual sales but also enhances its bargaining power in a tightening supply environment, potentially leading to increased order rates and service fee premiums [1]

昭衍新药（603127）(06127)发布公告，于2026年1月7日，注销有关2021年和2022年A股员工持股计划的 12.91万股库存股份。 ...

智通财经APP讯，昭衍新药(06127)发布公告，于2026年1月7日，注销有关2021年和2022年A股员工持股 计划的12.91万股库存股份。 ...

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 公司名稱： 北京昭衍新藥研究中心股份有限公司 呈交日期： 2026年1月7日 如上市發行人的已發行股份或庫存股份出現變動而須根據《香港聯合交易所有限公司（「香港聯交所」）證券上市規則》(「《主板上市規則》」)第13.25A條 / 《香港聯合交易所有限公司GEM證券 上市規則》(「《GEM上市規則》」)第17.27A條作出披露，必須填妥第一章節 。 | 第一章節 | | | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | | 1. 股份分類 | 普通股 | 股份類別 A | | | 於香港聯交所上市 | 否 | | | 證券代號 (如上市) | 603127 | 說明 | | | | | | | A. 已發行股份或庫存股份變動 | | | | | | | | | | | 已發行股份（不包括庫存股份）變動 | | | 庫存股份變動 | | | | 事件 | | 已發行股份（不包括庫存股份）數 目 | 佔 ...

Group 1 - The A-share market saw a collective rise in innovative drug concept stocks on January 7, with notable gains including a 20% increase for Beibete-U and over 17% for Yinos. [1] - Other significant performers included Chengdu XianDao with a 13% rise, and Panlong Pharmaceutical reaching a 10% increase. [1] - Additional stocks such as Yangguang Nuohuo and Zhaoyan New Drug also experienced gains exceeding 9% and 7% respectively. [1] Group 2 - The table lists various stocks with their respective codes, showing percentage increases, total market capitalization, and year-to-date performance. [2] - Beibete-U (688759) had a market cap of 18.6 billion with a year-to-date increase of 42.46%. [2] - Yinos (688710) reported a market cap of 7.611 billion and a year-to-date increase of 22.29%. [2] - Chengdu XianDao (688222) had a market cap of 12.2 billion and a year-to-date increase of 29.59%. [2] - Other stocks listed include Panlong Pharmaceutical (002864) with a market cap of 3.706 billion and a year-to-date increase of 13.07%, and Yangguang Nuohuo (688621) with a market cap of 8.188 billion and a year-to-date increase of 17.63%. [2]

Group 1 - The A-share market saw a collective rise in innovative drug concept stocks, with notable gains including a 20% limit up for Beibetter-U and over 17% increase for Yinos [1] - Other significant performers included Chengdu XianDao with over 13% rise, and Panlong Pharmaceutical with a 10% limit up [1] - Additional stocks such as Sunshine Nuohuo and Zhaoyan New Drug also experienced increases of over 9% and 7% respectively [1] Group 2 - The table lists various stocks with their respective price changes, total market capitalization, and year-to-date performance, highlighting Beibetter-U's market cap at 18.6 billion and a year-to-date increase of 42.46% [2] - Yinos has a market cap of 7.611 billion with a year-to-date increase of 22.29%, while Chengdu XianDao's market cap is 12.2 billion with a 29.59% increase [2] - Other notable stocks include Panlong Pharmaceutical with a market cap of 3.706 billion and a 13.07% year-to-date increase, and Sunshine Nuohuo with a market cap of 8.188 billion and a 17.63% increase [2]

Core Viewpoint - The company, Beijing Zhaoyan New Drug Research Center Co., Ltd., has decided to terminate its employee stock ownership plans for 2021 and 2022, leading to the repurchase and cancellation of a total of 129,114 shares [1][5]. Group 1: Employee Stock Ownership Plans - The 2021 A-share employee stock ownership plan was approved by the board and shareholders but was never established due to lack of participation [2]. - The 2022 A-share employee stock ownership plan was also approved, but the company later decided to terminate it [3][5]. Group 2: Share Repurchase and Cancellation - The company will cancel a total of 129,114 shares from the repurchase account due to the termination of the employee stock ownership plans [9]. - The cancellation of shares will change the total share capital from 749,477,334 shares to 749,348,220 shares [11]. Group 3: Decision Process and Compliance - The decision to terminate the employee stock ownership plans and cancel shares was made after careful consideration of the macroeconomic environment and was agreed upon by the participating employees [8]. - The company has ensured that the decision-making process and information disclosure comply with relevant laws and regulations [12].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 海外監管公告 中 國 北 京，2026年1月6日 於 本 公 告 日 期，董 事 會 包 括 主 席 兼 執 行 董 事 馮 宇 霞 女 士、執 行 董 事 高 大 鵬 先 生、孫 雲 霞 女 士、羅 樨 女 士 及 顧 靜 良 先 生，獨 立 非 執 行 董 事 張 帆 先 生、楊 福 全 先 生、陽 昌 雲 先 生 及 應 放 天 先 生，及 職 工 董 事 李 葉 女 士。 证券代码：603127 证券简称：昭衍新药 公告编号：2026-001 北京昭衍新药研究中心股份有限公司 本公告乃北京昭衍新藥研究中心股份有限公司（「本公司 ...