致：香港交易及結算所有限公司 公司名稱: 無錫藥明康德新藥開發股份有限公司 呈交日期: 2025年9月5日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02359 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 387,076,150 | RMB | | 1 RMB | | 387,076,150 | | 增加 / 減少 (-) | | | 91,150,340 | | | RMB | | 91,150,340 | | 本月底結存 | | | 478,226,490 | RMB | | 1 RMB | | 478,226,490 | | 2. 股份分類 | 普通股 | 股份類別 | A | | 於香港聯交所上市 (註1) | | 否 | | | --- | --- | --- | ...

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年8月31日 狀態: 重新提交 致：香港交易及結算所有限公司 公司名稱: 無錫藥明康德新藥開發股份有限公司 呈交日期: 2025年9月5日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02359 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 387,076,150 | RMB | | 1 RMB | | 387,076,150 | | 增加 / 減少 (-) | | | 91,150,340 | | | RMB | | 91,150,340 | | 本月底結存 | | | 478,226,490 | RMB | | 1 RMB | | 478,226,490 | | 2. 股份分類 ...

Company Overview - WuXi AppTec Co., Ltd. is a leading global pharmaceutical and biotechnology company, providing comprehensive services in drug discovery, development, and manufacturing [1] - The company was established on December 1, 2000, and went public on May 8, 2018 [1] - The main business segments include small molecule chemistry (78.37%), testing services (12.93%), biological services (6.02%), and other services (1.90%) [1] Stock Performance - On September 5, the stock price of WuXi AppTec increased by 5.09%, reaching 107.13 CNY per share, with a trading volume of 7.877 billion CNY and a turnover rate of 3.05% [1] - The total market capitalization of the company is approximately 316.195 billion CNY [1] Fund Holdings - The Shangyin Fengyi Mixed A Fund (011504) holds a position in WuXi AppTec, having reduced its holdings by 2,000 shares in the second quarter, now holding 10,000 shares, which represents 1.26% of the fund's net value [2] - The fund has achieved a floating profit of approximately 51,900 CNY from its investment in WuXi AppTec [2] Fund Manager Information - The fund manager of Shangyin Fengyi Mixed A is Gao Yong, who has been in the position for 8 years and 255 days [3] - The total asset size of the fund is 55.1468 million CNY, with a best return of 23.78% during Gao Yong's tenure [3]

9月5日，药明康德涨5.09%，截至发稿，报107.13元/股，成交78.76亿元，换手率3.05%，总市值3161.95 亿元。 长安沪深300非周期指数A（740101）基金经理为肖洁。 截至发稿，肖洁累计任职时间3年211天，现任基金资产总规模5.16亿元，任职期间最佳基金回报 27.32%， 任职期间最差基金回报-26.3%。 风险提示：市场有风险，投资需谨慎。本文为AI大模型自动发布，任何在本文出现的信息（包括但不 限于个股、评论、预测、图表、指标、理论、任何形式的表述等）均只作为参考，不构成个人投资建 议。 责任编辑：小浪快报 资料显示，无锡药明康德新药开发股份有限公司位于上海浦东新区外高桥保税区富特中路288号,香港铜 锣湾希慎道33号利园1期19楼1910室，成立日期2000年12月1日，上市日期2018年5月8日，公司主营业务 涉及小分子化学药的发现、研发及生产全方位、一体化平台服务,以全产业链平台的形式面向全球制药 企业提供各类新药的研发、生产及配套服务。主营业务收入构成为：化学业务78.37%，测试业务 12.93%，生物学业务6.02%，其他(补充)1.90%，其他业务0.79%。 从 ...

Company Overview - WuXi AppTec, established on December 1, 2000, is located in Shanghai and Hong Kong, and was listed on May 8, 2018. The company provides a comprehensive platform for the discovery, development, and manufacturing of small molecule drugs, serving global pharmaceutical companies [1] - The company's revenue composition is as follows: Chemical business 78.37%, Testing business 12.93%, Biological business 6.02%, Other (supplementary) 1.90%, Other business 0.79% [1] Stock Performance - On September 4, WuXi AppTec's stock fell by 5.04%, trading at 105.29 CNY per share, with a total transaction volume of 4.619 billion CNY and a turnover rate of 1.74%. The total market capitalization is 310.764 billion CNY [1] Fund Holdings - TaiKang Fund has a significant position in WuXi AppTec, with its Medical Health fund (159760) reducing its holdings by 10,200 shares in the second quarter, now holding 121,100 shares, which constitutes 10.52% of the fund's net value, making it the largest holding [2] - The Medical Health fund was established on December 6, 2021, with a latest scale of 80.0606 million CNY. Year-to-date returns are 22.55%, ranking 1802 out of 4222 in its category, while the one-year return is 37.42%, ranking 2442 out of 3789 [2]

来源：新浪证券-红岸工作室 9月3日，药明康德跌1.00%，成交额79.48亿元，换手率2.91%，总市值3272.63亿元。 异动分析 CRO概念+创新药+人民币贬值受益 1、公司是国际领先的开放式能力与技术平台,为全球生物医药行业提供全方位、一体化的新药研发和生 产服务。 2、国内医药外包行业龙头,是国内最早开始从事医药研发生产外包的CRO和CMO一体化公司,高层管理 团队共拥有超过200项的已授权和申请中的专利成果;其主营业务为小分子化学药的发现、研发及生产的 全方位、一体化平台服务,以全产业链平台的形式面向全球制药企业提供各类新药的研发、生产及配套 服务;公司还在境外提供医疗器械检测及境外精准医疗研发生产服务。 3、根据2024年年报，公司海外营收占比为78.67%，受益于人民币贬值。 (免责声明：分析内容来源于互联网，不构成投资建议，请投资者根据不同行情独立判断) 区间今日近3日近5日近10日近20日主力净流入-3.94亿2.88亿10.44亿-6167.27万-25.28亿 主力持仓 主力没有控盘，筹码分布非常分散，主力成交额38.23亿，占总成交额的9.91%。 技术面：筹码平均交易成本为84. ...

Group 1 - The proposal regarding the cancellation of the supervisory board, changes to the company's registered capital, and amendments to the articles of association needs to be submitted to the company's second extraordinary general meeting of shareholders in 2025 for review [1] - The shareholders' meeting will authorize the board of directors to handle the changes to the registered capital and amendments to the articles of association, with further authorization to the chairman or other designated individuals for related business registration and filing matters [1] Group 2 - The announcement is made by the board of directors of Wuxi AppTec Co., Ltd. on September 3, 2025 [2]

Core Viewpoint - WuXi AppTec is restructuring its organization to clarify the roles and responsibilities of its domestic operating entities and holding platforms, which includes transferring 98.9% of the shares of Hualan Pharmaceutical held by its subsidiary Shanghai WuXi to a newly established wholly-owned subsidiary, WuXi Research [1][2] Group 1: Company Actions - The share transfer involves WuXi AppTec transferring its entire 98.9% stake in Hualan Pharmaceutical to WuXi Research, which will directly hold these shares post-transfer [1] - This share transfer is within the board's authority and does not require shareholder approval, nor does it constitute a related party transaction or a major asset restructuring as per regulations [1] Group 2: Industry Context - The global CDMO industry is shifting from "capacity competition" to "technology + efficiency competition," with Hualan Pharmaceutical needing to adapt to technological advancements and evolving customer demands [2] - The restructuring aims to integrate resources between WuXi Research and Hualan Pharmaceutical, facilitating seamless transitions from research demands to production, which is crucial for maintaining Hualan's competitive edge in the small molecule sector [2] Group 3: Financial Implications - The share transfer is an internal asset reconfiguration that does not involve cash transactions, thus it will not significantly impact WuXi AppTec's financial statements [2] - The restructuring is expected to enhance overall operational efficiency in the long term, potentially leading to positive financial performance [2][3] Group 4: Future Considerations - The specific plan and implementation timeline for the share transfer remain uncertain, pending the signing of relevant agreements and approvals from tax authorities and business registration [3]

Core Viewpoint - WuXi AppTec is transferring 98.9% of its shares in Shanghai Hualian Pharmaceutical Co., Ltd. to WuXi AppTec (Shanghai) Pharmaceutical Development Co., Ltd. to optimize its organizational structure and enhance operational efficiency [1][3]. Company Summary - The share transfer is an internal asset reconfiguration and does not involve cash transactions, thus it will not significantly impact WuXi AppTec's financial statements [2]. - The transfer will not change the scope of consolidated financial statements or affect the operational activities of Hualian Pharmaceutical, nor will it impact its profits and overall equity [2]. - The restructuring aims to clarify the roles and responsibilities between domestic operating entities and holding platforms, enhancing the focus on core business areas [3]. Industry Summary - The global pharmaceutical CDMO industry is shifting from "capacity competition" to "technology + efficiency" competition, necessitating that Hualian Pharmaceutical adapt to technological advancements and evolving customer demands [1]. - The restructuring allows Hualian Pharmaceutical to concentrate on small molecule drug production processes, improving its professional capabilities while leveraging WuXi AppTec's global network to meet regional compliance and cost requirements [4]. - The specific implementation of the share transfer remains uncertain, pending the signing of relevant agreements and approvals from tax authorities and business registration [4].

Group 1 - The core point of the article is that WuXi AppTec announced the approval of several resolutions during its board meeting, including the cancellation of the supervisory board, changes to the company's registered capital, and amendments to the company's articles of association [2] Group 2 - The announcement was made on the evening of September 2, indicating a significant corporate governance change [2] - The resolutions will also involve the handling of business registration changes [2]