Group 1: Company Performance - In Q1, Hualan Biological achieved revenue of 868 million yuan, a year-on-year increase of 10.2% [1] - The net profit attributable to shareholders was 313 million yuan, up 19.62% year-on-year, while the net profit excluding non-recurring gains and losses was 300 million yuan, increasing by 35.35% [1] - The blood products segment generated revenue of 843 million yuan, with a year-on-year growth of 11.98% and a net profit of 291 million yuan, reflecting a 23.47% increase [1] Group 2: Vaccine Business - Hualan Vaccine reported Q1 revenue of 24.28 million yuan, a decline of 29.05% year-on-year, with a net profit of 32.78 million yuan, down 15.06% [2] - The net profit excluding non-recurring gains and losses was 15.42 million yuan, showing an increase of 8.89% [2] - The company anticipates that vaccine sales will improve in Q2 as product approvals and sales efforts ramp up [2] Group 3: Industry Trends - The plasma collection volume for Hualan Biological reached a record high of 1586.37 tons in 2024, marking an 18.18% increase [3] - The blood products industry is experiencing increased merger and acquisition activities, with plasma stations becoming a strategic focus for companies [3] - Notable acquisitions include Boya Biological's purchase of 100% of Green Cross China for 1.82 billion yuan, adding 4 plasma stations, and Tian Tan Biological's acquisition of 5 plasma stations from CSL Asia Pacific [3]

Investment Rating - Maintain Outperform rating with a target price adjusted to RMB 32.50 [1][9] Core Views - The company has cleared goodwill impairment risks and is expanding plasma collection stations through both organic and external growth, establishing a foundation for future growth. The potential impact of tariffs on imported albumin may benefit domestic albumin products [1][9] - The company reported a full-year revenue of RMB 1.74 billion, a decrease of 34.58%, while net profit increased by 67.18% to RMB 397 million, primarily due to a low base from goodwill impairment in 2023 [1][9] - The product structure is continuously optimized, with blood product revenue growing by 4.32% to RMB 1.51 billion, despite a slight decline in gross profit margin [1][9] Financial Summary - Revenue and profit forecasts for 2024-2027 show a recovery trend, with net profit expected to reach RMB 753 million by 2027, reflecting a compound annual growth rate [3][6] - The company has a projected EPS of RMB 1.16 for 2025 and RMB 1.50 for 2027, with a PE ratio of 28X for 2025 [1][9] - The company has 20 operating plasma stations and plans to increase plasma collection volume to 630.6 tons in 2024, a 10.4% increase [1][9]

Investment Rating - The report maintains an "Outperform" rating for the company, with a target price adjusted to RMB 32.50 [1][9]. Core Insights - The company has cleared goodwill impairment risks and is expanding its plasma collection stations through both organic growth and acquisitions, establishing a foundation for future growth. The potential impact of tariffs on imported albumin may benefit domestic albumin products [1][9]. - The company reported a full-year revenue of RMB 1.74 billion in 2024, a decrease of 34.58%, while net profit increased by 67.18% to RMB 397 million, primarily due to a low base from goodwill impairment in 2023 [1][9]. - The product structure is continuously optimized, with blood product revenue growing by 4.32% to RMB 1.51 billion in 2024, despite a slight decline in gross profit margin [1][9]. Financial Summary - Revenue and profit forecasts for the upcoming years have been adjusted, with 2025 EPS projected at RMB 1.16 and 2026 EPS at RMB 1.33, while a new forecast for 2027 EPS is set at RMB 1.50 [1][9]. - The company is expected to maintain a steady growth trajectory, with plasma collection volume projected to reach 630.6 tons in 2024, reflecting a 10.4% increase [1][9]. - The financial outlook includes a projected net profit of RMB 585 million for 2025, with a net profit margin expected to improve over the years [1][9].

Investment Rating - The industry investment rating is "Outperform the Market - A" [4] Core Viewpoints - The report highlights a steady growth in domestic albumin batch approvals, with a 12% year-on-year increase in Q1 2025, while imported albumin saw a 9% decline [9][10] - The report suggests a long-term growth potential in the immunoglobulin market, with a 15% year-on-year increase in intravenous immunoglobulin (IVIG) approvals in Q1 2025 [18][24] - The report identifies key companies to watch, including Tian Tan Biological, Pai Lin Biological, Bo Ya Biological, Shanghai Lai Shi, and Hua Lan Biological [3] Summary by Sections 1. Overview of Blood Product Batch Approvals in Q1 2025 - Domestic albumin approvals reached 418 batches, up 12% year-on-year, while imported albumin approvals totaled 778 batches, down 9% [9][10] - Intravenous immunoglobulin (IVIG) approvals were 324 batches, up 15%, and intramuscular immunoglobulin (IMIG) approvals were 9 batches, up 13% [9] - For specific immunoglobulins, hepatitis B immunoglobulin approvals were 11 batches (up 83%), tetanus immunoglobulin 35 batches (up 13%), and rabies immunoglobulin 34 batches (up 42%) [9] 2. Albumin Analysis - The report notes a compound annual growth rate (CAGR) of 11.4% for albumin approvals from 2011 to 2024, with domestic albumin growing at 5.9% and imported at 16.7% [11] - In Q1 2025, the total albumin approvals were 1196 batches, reflecting a slight decline of 2.4% year-on-year [11] 3. Immunoglobulin Analysis - The report indicates a CAGR of 8.4% for IVIG approvals from 2011 to 2024, with Q1 2025 showing 324 batches approved [18] - The leading companies in the IVIG market accounted for approximately 61% of the market share in Q1 2025 [24] 4. Special Immunoglobulins - The report highlights significant growth in specific immunoglobulin approvals, particularly for hepatitis B and rabies, with notable increases in batch approvals [28][29] - The market for tetanus immunoglobulin is also growing, with a 13% increase in approvals [28] 5. Coagulation Factor Analysis - The report notes a CAGR of 13.6% for human coagulation factor VIII approvals from 2011 to 2024, with Q1 2025 approvals at 163 batches, up 12% [35] - Prothrombin complex concentrate (PCC) approvals increased by 26% year-on-year, totaling 82 batches in Q1 2025 [35] - The report identifies leading companies in the coagulation factor market, which hold significant market shares [43]

NO.1 万泰生物一季度净亏损5300万元 丨2025年4月25日星期五丨 点评：东地块的公司智能工厂（一期）建设项目正常推进，项目具备年处理血浆1200~1500吨生产能 力。西地块因规划环评未完成被收储，补偿价格公允，未损害股东利益。 NO.4 甘李药业去年研发投入超归母净利润 4月24日晚间，甘李药业发布2024年年报。甘李药业2024年实现总营业收入30.45亿元，同比增长 16.77%；利润总额达到6.30亿元，同比增长105.91%；实现归母净利润6.15亿元，同比增长80.75%。 2024年，甘李药业研发投入6.45亿元，占营业收入的21.20%，较上年有所增加。 点评：甘李药业通过研发高壁垒生物类似药与创新管线持续强化竞争力，未来在糖尿病及代谢疾病领域 的发展潜力值得关注。 2025年一季度，万泰生物实现总营业收入4.01亿元，同比减少46.76%；利润总额达到-0.58亿元，同比减 少146.08%；实现归母净利润-0.53亿元，同比减少141.98%。 点评：长期看，公司技术平台（大肠杆菌表达系统）仍具竞争力，但需加速九价苗临床进度及国际化布 局以扭转颓势。 NO.2 恒瑞医药一季度归母 ...

博雅生物（300294）公告，2025年第一季度营收为5.36亿元，同比增长19.49%；净利润为1.39亿元，同 比下降8.25%。 ...

证券代码：300294 证券简称：博雅生物 公告编号：2025-031 华润博雅生物制药集团股份有限公司 关于募集资金投资项目部分用地被收储的公告 本公司及董事会全体成员保证公告内容真实、准确和完整，没有虚假记载、 误导性陈述或重大遗漏。 上述募集资金到位情况业经江苏公证天业会计师事务所（特殊普通合伙）验 证，并出具苏公W[2018]B041号《验资报告》。 （二）募集资金使用和结余情况 为达成公司战略目标，华润博雅生物制药集团股份有限公司（以下简称公司 或博雅生物）使用2018年度募集资金（含利息）及自筹资金建设"血液制品智能 工厂（一期）建设项目"（以下简称本募投项目或智能工厂项目），该项目用地 涉及东地块（322.74亩），西地块（217.92亩、117.18亩；合计335.10亩）三宗合 计657.84亩的工业用地土地使用权。现因受地方政府规划环评未完成等原因影响， 西地块未能在约定的时间内开工建设，经抚州高新技术产业开发区管理委员会 （以下简称区管委会）研究，对公司智能工厂项目西地块（217.92亩、117.18亩； 合计335.10亩）的两宗国有建设用地进行土地收储。经双方协商，区管委会与公 司拟 ...

公司监事会认为：公司董事会审核公司 2025 年第一季度报告的程序符合法 律、行政法规和中国证监会的规定。2025 年第一季度报告真实、准确、完整地 反映了公司的实际情况，不存在任何虚假记载，误导性陈述或者重大遗漏。 具体内容详见同日在巨潮资讯网（网址：http://www.cninfo.com.cn）披露的 《2025 年第一季度报告》。 证券代码：300294 证券简称：博雅生物 公告编号：2025-029 华润博雅生物制药集团股份有限公司 第八届监事会第九次会议决议公告 本公司及监事会全体成员保证公告内容真实，准确和完整，没有虚假记载， 误导性陈述或重大遗漏。 一、监事会会议召开情况 华润博雅生物制药集团股份有限公司（以下简称公司）第八届监事会第九次 会议于 2025 年 4 月 20 日以邮件及通讯方式通知，并于 2025 年 4 月 23 日在公司 会议室以现场加通讯表决的方式召开。会议应参加表决监事 3 人，实参加表决监 事 3 人。会议由监事会主席周娇女士主持，公司部分高级管理人员列席会议。本 次会议符合《中华人民共和国公司法》《中华人民共和国证券法》《深圳证券交 易所创业板股票上市规则》《深圳 ...

证券代码：300294 证券简称：博雅生物 公告编号：2025-028 华润博雅生物制药集团股份有限公司 第八届董事会第十一次会议决议公告 本公司及董事会全体成员保证公告内容真实、准确和完整，没有虚假记载、 误导性陈述或重大遗漏。 一、董事会会议召开情况 华润博雅生物制药集团股份有限公司（以下简称公司）第八届董事会第十一 次会议于 2025 年 4 月 20 日以邮件及通讯方式通知，并于 2025 年 4 月 23 日在公 司会议室以现场加通讯表决的方式召开。会议应参加表决董事 9 人，实参加表决 董事 9 人。会议由董事长邱凯先生主持，公司全体监事出席会议，全体高级管理 人员列席会议。本次会议符合《中华人民共和国公司法》《中华人民共和国证券 法》《深圳证券交易所创业板股票上市规则》《深圳证券交易所上市公司自律监 管指引第 2 号——创业板上市公司规范运作》及《公司章程》等相关规定。经充 分讨论，审议通过了以下议案。 具体内容详见同日在巨潮资讯网（网址：http://www.cninfo.com.cn）披露的 《2025 年第一季度报告》。 表决结果：9 票同意，0 票反对，0 票弃权。 2、审议通过《关于募 ...

Financial Performance - The company's operating revenue for Q1 2025 was CNY 535,876,732.90, representing a 19.49% increase compared to CNY 448,452,537.26 in the same period last year[2] - The net profit attributable to shareholders decreased by 8.25% to CNY 139,484,155.03 from CNY 152,024,886.81 year-on-year[3] - The net profit attributable to shareholders after deducting non-recurring gains and losses fell by 19.67% to CNY 102,261,123.10, down from CNY 127,306,750.41 in the previous year[3] - Operating profit for the current period was ¥162,436,766.94, a decrease of 7% from ¥174,748,795.31 in the previous period[19] - Net profit for the current period was ¥139,291,778.48, down 8.1% from ¥151,760,842.43 in the previous period[19] - The net profit attributable to the parent company was approximately ¥139.48 million, a decrease from ¥152.02 million in the previous period, representing a decline of about 8.5%[20] - The total comprehensive income attributable to the parent company was approximately ¥139.11 million, down from ¥152.02 million, reflecting a decrease of around 8.5%[20] - Basic and diluted earnings per share were both ¥0.28, compared to ¥0.30 in the previous period, indicating a decline of approximately 6.67%[20] Cash Flow - The net cash flow from operating activities was negative CNY 42,119,496.62, a decline of 134.00% compared to a positive CNY 123,871,710.13 in the same period last year[4] - Cash inflows from operating activities totaled approximately ¥427.20 million, slightly down from ¥433.67 million, a decrease of about 1.1%[21] - Cash outflows from operating activities increased significantly to approximately ¥469.32 million from ¥309.79 million, resulting in a net cash flow from operating activities of approximately -¥42.12 million[22] - Cash inflows from investment activities were approximately ¥1.45 billion, up from ¥922.01 million, marking an increase of about 57.3%[22] - Cash outflows from investment activities rose to approximately ¥2.12 billion from ¥1.15 billion, leading to a net cash flow from investment activities of approximately -¥669.31 million[22] - The ending cash and cash equivalents balance was approximately ¥585.46 million, down from ¥1.84 billion, indicating a decrease of about 68.3%[22] - The company reported a significant increase in payments to employees, totaling approximately ¥121.99 million, compared to ¥94.45 million in the previous period, an increase of about 29.4%[22] - The company’s cash flow from financing activities resulted in a net outflow of approximately -¥1.70 million, compared to -¥52,856.64 in the previous period, indicating a larger outflow[22] Assets and Liabilities - Total assets at the end of the reporting period increased by 0.92% to CNY 8,478,706,583.73 from CNY 8,401,144,768.99 at the end of the previous year[2] - Total liabilities decreased to ¥852,022,450.92 from ¥913,381,994.27, a reduction of 6.7%[17] - Cash and cash equivalents decreased to ¥586,740,774.48 from ¥1,299,851,770.61, a decline of 54.8%[16] - Inventory slightly decreased to ¥983,308,049.53 from ¥995,427,153.22, a reduction of 1.4%[16] - Non-current assets increased to ¥3,431,232,325.36 from ¥3,342,794,636.95, an increase of 2.6%[17] - The total equity attributable to the parent company increased to ¥7,626,264,685.05 from ¥7,487,150,950.41, reflecting a growth of 1.9%[18] Shareholder Information - The total number of common shareholders at the end of the reporting period is 27,155[10] - The largest shareholder, China Resources Pharmaceutical Group, holds 30.45% of shares, totaling 153,540,253 shares[10] - Shenzhen Gaotejia Investment Group holds 11.31% of shares, totaling 57,049,640 shares, with 16,450,000 shares pledged[10] - The top ten shareholders collectively hold significant stakes, with the top three accounting for over 45% of total shares[10] - The company has a total of 0 preferred shareholders at the end of the reporting period[10] - The company has not reported any changes in the number of restricted shares during the reporting period[12] Research and Development - Research and development expenses decreased by 44.40% to CNY 10,566,848.19, primarily due to reduced investment in the Pibin project compared to the previous year[9] - Research and development expenses for the current period were ¥10,566,848.19, down 44.5% from ¥19,006,039.85 in the previous period[19] Regulatory Approvals - The company received approval to set up a blood plasma collection station in Daqing, Inner Mongolia, as of January 2025[12] - The company obtained a clinical trial approval for subcutaneous immunoglobulin for primary immunodeficiency disease in April 2025[13] Shareholder Actions - The controlling shareholder plans to increase its stake by at least 1% (5,042,400 shares) within six months starting from November 8, 2024[14] - As of April 8, 2025, the controlling shareholder has cumulatively increased its stake by 1.17% (5,899,700 shares) since November 8, 2024[14] Impact of Acquisitions - The company's gross profit margin was impacted by the acquisition of Green Cross, with operating costs rising by 71.38% to CNY 247,566,329.70[8] - The company reported a significant increase in accounts receivable by 31.94% to CNY 591,733,607.73, attributed to revenue growth and a decline in cash collections[8]