分子育种

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扬大团队发现控制垩白的关键基因
Xin Hua Ri Bao· 2025-07-29 21:26
7月下旬,一场关乎稻米产量和品质的"隐形较量",正在每一粒稻谷内部悄然上演——是粒粒晶莹剔 透,还是会出现恼人的"垩白"?垩白,表现为稻米上不透明的斑块,是稻米胚乳在发育过程中,淀粉颗 粒与蛋白质基质合成节奏失衡所导致的结构性缺陷,是影响稻米外观品质的重要因素。 □ 本报记者叶真 水稻垩白的形成,是一个复杂的系统工程。"淀粉与蛋白质作为这一过程的两大主角,其合成速率必须 严丝合缝、高度协同,"论文第一作者,扬州大学农学院教师胡智介绍,"一旦节奏失控,一方慢了半拍 或快了半步,籽粒内部就会形成垩白区域。" 然而,这个庞大生物过程的总"指挥"是谁?背后的分子开关在哪?为了寻找答案,团队开始"大海捞 针"。"首先我们构建了一个核心籼稻种质资源库,之后通过全基因组关联分析、标记筛选位点等方法, 锁定了关键基因Chalk9。"胡智解释,他们通过进一步分子试验发现,该基因编码一种E3泛素连接酶, 通过调控OsEBP89转录因子的蛋白稳态,确保淀粉与蛋白质合成"同频共振"。"具体来说,当Chalk9基 因功能减弱,OsEBP89蛋白就会积累更多,就会出现垩白。" 在深入解析Chalk9过程中,研究人员还发现了一个振奋人心的 ...
我国科学家发现调控水稻抽穗期的关键基因
Ke Ji Ri Bao· 2025-06-20 07:12
Core Insights - The research team led by academician Wan Jianmin has identified a new gene, ELD1, that specifically regulates the heading date of rice under long-day conditions, which is crucial for breeding high-yield, high-quality, and widely adaptable rice varieties [1][2] - The study reveals that the ELD1 gene can significantly promote heading without causing obvious agronomic defects, indicating its potential for molecular breeding applications [2] Group 1: Gene Discovery and Mechanism - The ELD1 gene regulates the mRNA splicing of the core biological clock gene OsCCA1, affecting the heading date of rice [1] - The research indicates that shorter light exposure leads to faster heading and earlier maturity in rice [1] - ELD1 interacts with OsNKAP protein and multiple core mRNA splicing factors, influencing the splicing of thousands of genes across the genome [1] Group 2: Implications for Breeding - The study provides a new mechanism for understanding how light signals regulate the heading date of rice, which is significant for molecular breeding [2] - The team utilized base editing technology to create targeted mutations in key amino acids of ELD1, resulting in new early-heading germplasm for high-quality rice varieties such as Ningjing 7 and Ningjing 4 [2] - This research offers important genetic resources and theoretical support for addressing the late maturity issues in hybrid rice breeding [2]
华智生物将向巴基斯坦输出分子育种技术
Xin Hua Cai Jing· 2025-05-08 14:48
Group 1 - Huazhi Biotechnology Co., Ltd. is collaborating with Pakistan to transfer molecular breeding technology, aiming to establish a national-level molecular breeding joint laboratory in Pakistan [1][3] - A memorandum of understanding was signed among Huazhi Biotechnology, Beijing Jiaolong Technology Co., Ltd., and Hassan Trading Company for comprehensive cooperation in the field of molecular-assisted breeding [1] - The cooperation will involve sharing germplasm resource databases and utilizing Huazhi's "genotype-phenotype" big data platform to aggregate superior genes [1] Group 2 - The collaboration is expected to enhance Pakistan's agricultural system, enabling the cultivation of "future seeds" that are resilient to climate change, thereby significantly increasing food production and farmers' income [1][2] - Huazhi Biotechnology aims to help Pakistan overcome breeding bottlenecks through technology sharing and promote the international application of China's seed industry "chip" technology [2] - Huazhi Biotechnology is a national-level molecular breeding platform guided by the Ministry of Agriculture and Rural Affairs, established in collaboration with leading seed companies [3]