Core Viewpoint - A novel non-invasive method for brain stimulation using microelectrodes delivered via immune cells has been developed, potentially revolutionizing the treatment of neurological diseases without the need for invasive surgery [1][2][3]. Group 1: Research Background - Traditional treatments for brain diseases like Parkinson's and epilepsy often require invasive electrode implantation through craniotomy, which carries risks of infection and tissue damage [1]. - Existing non-invasive techniques, such as transcranial magnetic stimulation, lack the spatial resolution needed for precise neuronal control [1]. Group 2: Innovative Technology - The research team introduced a biological "delivery" system named "Circulatronics," utilizing subcellular-sized wireless electronic devices (SWEDs) that are approximately 10 micrometers in diameter [2]. - These devices can be powered wirelessly by near-infrared light, which penetrates several centimeters of tissue, including the skull and brain [2]. Group 3: Experimental Validation - In experiments, the team induced localized inflammation in the brains of mice and injected the "cell-electronic" hybrids, which successfully targeted the inflamed areas [3]. - The devices were activated by external near-infrared light, demonstrating precise stimulation of surrounding neurons with a spatial accuracy of 30 micrometers [3]. Group 4: Future Implications - The technology could potentially eliminate the need for craniotomy in treating various inflammation-related neurological diseases, such as Alzheimer's and post-stroke conditions [3]. - There is potential for broader applications by using different types of immune cells for targeting other diseases in various body parts [3]. Group 5: Current Limitations - The technology is still in early animal testing stages, and improvements in targeting efficiency and long-term safety need to be validated through larger studies [4].

Core Insights - A new method developed by the Medical University of Vienna and Imperial College London allows for precise capture and decoding of hidden neural signals in the residual limbs of upper limb amputees, translating them into accurate movement commands for prosthetic limbs [1][2] Group 1: Research and Development - The research involved implanting a novel 40-channel microelectrode array into three upper limb amputee volunteers, utilizing targeted muscle reinnervation (TMR) surgery to create a new biological interface [1] - TMR surgery reconnects residual arm nerves to remaining muscles, enabling the detection of neural signals originally used to control the hand and arm [1] - The team achieved direct measurement of individual motor neuron activity located in the spinal cord, which transmits movement commands from the brain to the muscles [1] Group 2: Implications for Prosthetics - This breakthrough indicates that future prosthetic limbs will no longer rely on simple muscle contraction patterns for coarse control but will respond to users' finer and more natural movement intentions [2] - The current research lays the groundwork for the development of next-generation wireless implantable devices, which may enable real-time wireless transmission of neural signals to prosthetic hands or other assistive systems [2] - Ultimately, this technology aims to help amputees regain near-natural limb functionality [2]

Core Insights - The third National Postdoctoral Innovation and Entrepreneurship Competition showcased the increasing collaboration between research teams and industries, emphasizing the practical applicability of research outcomes [1][6] - The competition attracted 8,006 projects and 36,000 participants, highlighting the growing interest in innovative technologies across various sectors [4][8] - The event underscored the importance of young scientific talent as a bridge between research and industry, driving innovation and addressing market needs [1][12] Group 1: Event Overview - The competition took place from October 26 to 28 in Quanzhou, Fujian, featuring significant participation from various sectors [1] - A total of 2,100 companies, 20 industry associations, and 13 venture capital institutions engaged with project teams during the event, resulting in 220 intended cooperation projects and 150 signed agreements [8] Group 2: Technological Innovations - A new device developed by a postdoctoral team allows for painless home testing of multiple health indicators, addressing the needs of chronic disease patients [2][5] - The device utilizes 3D microstructure printing technology to enhance the efficiency of biological sample extraction, positioning it as a leading solution in the field [4] Group 3: Industry Collaboration - Companies are increasingly recognizing the value of practical research solutions, as evidenced by the collaboration between Guangdong Lingnan Big Health Ecological Technology Group and South China University of Technology to improve the preservation technology of dried tangerine peel [1][6] - The competition has led to significant interest from venture capital firms, particularly in artificial intelligence projects, indicating a shift towards seed-stage investments focused on innovation potential rather than immediate financial returns [4][8] Group 4: Talent Development Strategies - The event highlighted a shift in talent strategy, emphasizing the need for investment in human resources to drive technological innovation and industry growth [9][10] - Cities like Jinjiang are implementing mechanisms to integrate entrepreneurs and scientists, fostering an environment conducive to innovation and project commercialization [10]

Core Insights - The article highlights the development of a billion-level "Northern Bio Valley" in Dezhou, focusing on the growth of the biotechnology industry through collaboration and innovation [1][2][4] Industry Overview - Dezhou is concentrating on five key areas within the biotechnology sector: biomanufacturing, biomedicine, bio-agriculture, biomedical engineering, and biomass energy, aiming for high-end, clustered, and international development [2][3] - The city has established a clear framework for its biotechnology industry, with 153 enterprises in the sector and projected revenue of 40.4 billion yuan in 2024 [2] Innovation and Collaboration - Innovation is identified as the core driver for overcoming challenges and seizing development opportunities, supported by numerous national and provincial innovation platforms [3] - Dezhou has established long-term collaborations with over 40 universities and research institutions, holding nearly 300 patents related to biopreparation [3] Regional Development - Different regions within Dezhou are focusing on specific areas of biotechnology, such as biomanufacturing in Yucheng and medical devices in Qihe, creating a diverse and collaborative development landscape [4] - The city has mechanisms in place for regular roadshows and result transformation, targeting investors, entrepreneurs, and industry experts to facilitate efficient connections among technology, capital, market, and policy [4] Future Outlook - Dezhou aims to target cutting-edge fields such as synthetic biology, gene cell therapy, and AI pharmaceuticals, with plans to establish high-level innovation platforms and pilot bases [4] - The city is committed to enhancing its industrial cluster development, optimizing its industrial layout, and attracting leading enterprises and major projects to achieve the goal of becoming a billion-level "Northern Bio Valley" [4]

图① 八字 JONHOST STSOO8 YTIUNGSAE ED 图2 图③ 中国国际大学生创新大赛（2025）总决赛举办地。 韩堃霖摄 10月13日至15日，中国国际大学生创新大赛（2025）总决赛在河南郑州举办，广大青年学生敢于做先 锋，用在课堂和实验室学到的知识解决实际问题，在创新实践中增本领、长才干。 高校毕业生等青年是创新创业的生力军，支持其创业有利于更好发挥创业带动就业的倍增效应，激发全 社会的创新创造活力。本期教育版聚焦大学生创业，见证一个个"金点子"结出"金果实"的故事，瞩望广 大青年在中国式现代化的广阔天地中更好展现才华。 ——编 者 创业项目如何选择？ 把市场堵点当作创业起点 本报记者 刘晓宇 "耐高温、个头大、出肉多，我们的鲍鱼苗可以在福建海域安然度夏！"近日，在中国国际大学生创新大 赛（2025）现场，闽江学院物理与电子信息工程学院学生林昕哲（见图①左，受访者供图）带领的项 目，获得佳绩。 "不耐高温一直是制约南方鲍鱼发展的重要因素。"林昕哲家住漳州市漳浦县霞美镇北江村，从小目睹 了"南鲍北养"的转运辛劳。 "鲍鱼生存温度是18至24摄氏度，初夏时全村的鲍鱼都要运到北方海域度夏。转运 ...

Core Insights - The rapid advancements in biomedical engineering are reshaping the future of human health, with innovations such as 3D bioprinting of organs and tissues becoming increasingly feasible [3][20] - Significant breakthroughs include the successful cultivation of a living heart organoid and the discovery of a molecular switch for organ regeneration in mammals [1][4] Group 1: Innovations in Biomedical Engineering - The first living heart organoid over 1 cm in diameter was successfully cultivated in Shanghai, offering new hope for organ transplantation [1][4] - Researchers have developed a method to 3D print active organoids using bioprinting technology, which can replicate the structure and function of real organs [4][20] - The production of bioprinting materials involves creating billions of living cells, which are cultivated in specialized environments to ensure rapid and large-scale expansion [6][8] Group 2: Applications of Bioprinting - Bioprinting technology is being utilized for drug testing, allowing for the creation of mini-tumor models that can simulate patient responses to various treatments [16][18] - The development of in-situ printing techniques enables the direct repair of damaged tissues within the body, such as printing new skin or heart patches [18][20] Group 3: Cross-Disciplinary Collaborations - Collaborative efforts among multiple research institutions have led to the creation of a novel visual prosthetic that allows blind animals to perceive infrared light, showcasing the potential of interdisciplinary research in biomedical engineering [21][27] - The integration of nanomaterials and advanced engineering techniques has resulted in significant improvements in the functionality and efficiency of bioelectronic devices [25][27] Group 4: Strategic Development in Life Sciences - The Chinese government is prioritizing life sciences in its strategic development plans, with initiatives aimed at accelerating the commercialization of cutting-edge technologies in cell and gene therapy [28] - Cities like Shanghai and Shenzhen are actively fostering innovation ecosystems around organoids and biomanufacturing, with ambitious targets for the growth of the biopharmaceutical industry [28]

Core Viewpoint - The article discusses the development of a biodegradable biohydrogel battery that addresses the limitations of traditional batteries in biomedical applications, emphasizing the need for high-performance energy sources that are compatible with biological systems [4][7]. Group 1: Biohydrogel Battery Development - Researchers from Zhejiang University have designed a biodegradable biohydrogel battery using light polymerization and 3D printing techniques, showcasing excellent mechanical properties and biocompatibility [4]. - The biohydrogel battery operates at a voltage of 1.5 V, providing a current range of 0.001-6 mA, which supports tissue regeneration and cardiac pacing applications [4][8]. Group 2: Hydrogel Characteristics and Applications - Hydrogels, as three-dimensional cross-linked polymer networks, exhibit properties similar to biological tissues, making them suitable for various biomedical applications such as drug delivery and tissue engineering [6]. - The integration of gallium-based liquid metals with hydrogels enhances their conductivity and mechanical performance, promoting their use in flexible bioelectronic devices [6]. Group 3: Challenges and Solutions in Energy Systems - Traditional batteries face significant limitations in biomedical applications due to poor biocompatibility, non-degradability, and rigidity, which can harm surrounding tissues [7]. - The development of a flexible, biodegradable power source using conductive ion hydrogels and InGa3-Cu nanoparticles addresses these challenges, maintaining stable current during degradation [7]. Group 4: Performance Metrics - The biohydrogel battery features a high printing precision of 50 micrometers, with tensile strain and compression rates of 200% and 95%, respectively, aligning with the mechanical properties of biological tissues [8]. - It operates in dual current modes, facilitating microcurrent for tissue regeneration and high current for effective cardiac pacing [8].

Core Viewpoint - Russian scientists have developed a biodegradable implant with shape memory functionality for treating animal joint injuries, which can accelerate recovery and reduce complications, making veterinary services more convenient [1][2]. Group 1: Implant Features - The implant is designed to fix diseased joints in animals and gradually degrade safely within the body, eliminating the need for secondary surgeries [2]. - The material used in the implant has shape memory properties, allowing it to adapt precisely to the anatomical structure of the affected animal, thus speeding up postoperative recovery and minimizing complications [2][3]. - The implant is made from 3D-printed biodegradable polymers filled with hydroxyapatite and silica, enhancing structural strength and compatibility with bone tissue [2][3]. Group 2: Clinical Implications - The implant serves as an "internal cast," suitable for both small animals, like dogs with comminuted fractures, and large animals with intra-articular fractures, allowing joints to rest [5]. - The combination of biodegradable and shape memory functionalities in the implant is expected to improve the accessibility of joint fixation surgeries [5]. - Future studies will focus on the implant's self-positioning ability, biocompatibility, and effectiveness in live animals [3]. Group 3: Technological Advancements - The use of advanced additive manufacturing techniques and 3D printing in biomedical and bioengineering fields shows significant potential for future developments [5].

Group 1: Event Overview - The investor relations activity took place from July 2 to July 24, 2025 [2] - The event was held at the New Industry Biomedical Building, located at 23 Jinxiu East Road, Kengzi Street, Pingshan District, Shenzhen [2] - A total of 10 institutions participated, with 12 attendees [2] Group 2: Participants - Participating institutions included GIC Private Limited, Tiger Pacific Capital LP, and Huaneng Guicheng Trust Co., Ltd. [4] - Other notable participants were Jiangxi Peter Mingqi Private Fund Management Co., Ltd. and Shanghai Chongyang Investment Management Co., Ltd. [4] Group 3: Company Representatives - The event featured company representatives such as Zhang Lei, the Deputy General Manager and Board Secretary [2] - Investor relations were managed by Lu Yuning, the head of investor relations [2] Group 4: Content Summary - No new major interactive content was introduced beyond previously disclosed investor relations activities [2]

Core Insights - The forum focused on the strategic significance of brain-computer interface (BCI) technology in future technological development and industrial transformation [1] - Nearly a hundred experts and scholars from various fields participated, discussing the latest research and clinical applications of BCI technology [1] Group 1: Forum Overview - The 27th China Association for Science and Technology Annual Conference featured a specialized forum on brain-computer interfaces and intelligent innovation [1] - The forum was hosted by the China Association for Science and Technology and organized by the Chinese Rehabilitation Medicine Association [1] Group 2: Key Presentations - Zhao Jizong from the Chinese Academy of Sciences presented on clinical experimental research related to BCIs [3] - Yan Tianyi from Beijing Institute of Technology discussed non-invasive neural modulation technologies and their applications [5] - Liu Hesheng, Chief Scientist at Changping Laboratory, reported on brain function localization and regulation [5] - Chen Xun from the University of Science and Technology of China presented on multi-source neural signal computation [7] - He Huiguang from the Chinese Academy of Automation discussed visual restoration and reconstruction based on BCIs [7] - Shan Chunlei, Dean of the Rehabilitation Research Institute at Shanghai Jiao Tong University, shared insights on the empowerment of functional rehabilitation through BCIs [9] - Li Yuanqing from South China University of Technology highlighted BCIs as a frontier technology benefiting humanity [9] - Wu Wen from Southern Medical University discussed the application of BCI technology in motor rehabilitation [11] Group 3: Expert Discussions - Following the main presentations, experts engaged in discussions on topics such as the accuracy of neural signal encoding and decoding, the development of invasive and non-invasive BCIs, and the standardization of BCI technology [20] - The discussions also covered the exploration of talent cultivation models for BCI technology [20]