Group 1 - The article highlights the transformation of Taohua Mountain from a historical site of resistance during the Anti-Japanese War to a modern integrated tourism, leisure, and vacation forest park, leveraging red culture and ecological resources [6][10] - The local economy has diversified with the development of specialty agriculture and cultural tourism projects, leading to significant improvements in living standards and the eradication of poverty in 28 villages by 2017 [10][18] - The region has seen a substantial increase in agricultural productivity, with over 5,000 acres of wrinkled tangerines bearing fruit, indicating a successful agricultural initiative [8][10] Group 2 - Huarong County has actively aligned with the Yangtze River Economic Belt development strategy, enhancing its industrial layout, including the recent launch of a coal-water transport and storage base [12][14] - The county's industrial structure has evolved to focus on modern agriculture, green food processing, textile manufacturing, general equipment manufacturing, and biomanufacturing, with 60 national high-tech enterprises and 27 specialized enterprises [16] - The GDP of Huarong County has increased from 20.41 billion yuan in 2012 to 41.67 billion yuan in 2024, while rural residents' per capita disposable income has risen from 8,860 yuan to 30,296 yuan, marking a 241.9% increase [18]

Core Points - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI with bio-manufacturing, green chemicals, new materials, future food, and future agriculture [2][3] - The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [2][3] - Various activities will take place during the conference, including a Youth Forum on Bio-Manufacturing, a high-level roundtable discussion, and a closed-door seminar on the "2025 AI Empowering Bio-Manufacturing Industry Innovation Development Blue Book" [2][3][20] Organizational Structure - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by several institutions, including Peking University Ningbo Institute of Ocean Medicine and Ningbo Meisai Bioengineering Co., Ltd. [3] - Supporting organizations include the Chinese Society of Biotechnology's Bio-based Materials Committee and various regional bio-manufacturing alliances [3] Conference Agenda - The agenda includes registration, high-level discussions, and thematic forums on topics such as green chemicals and new materials, AI-driven innovations in bio-manufacturing, and future food and agriculture [6][7][21] - Specific sessions will cover topics like enzyme molecular engineering, bio-based carboxylic acid conversion, and the design of humanized "4D" collagen proteins [11][12][17][25] Special Acknowledgments - Several companies and institutions have been acknowledged for their support, including Ningbo Meisai Bioengineering Co., Ltd., Peking University Ningbo Institute of Ocean Medicine, and various technology firms [4] Industry Insights - The conference will also feature the release of the "China Synthetic Biology Industry Distribution Map (2025 Edition)" and a list of over 500 representative bio-manufacturing enterprises in China [50][51] - The event aims to facilitate technology transfer, product scaling, and talent acquisition within the bio-manufacturing sector [2][3]

Core Viewpoint - The article discusses the construction project of a collagen production line by Shandong Furida Biotechnology Co., Ltd., highlighting its investment, production capacity, and timeline for completion [2]. Summary by Sections Project Progress - Shandong Furida Biotechnology Co., Ltd. is expanding its collagen production line, located in Linyi City, Shandong Province, with a total investment of 12 million yuan, including 500,000 yuan for environmental protection [2]. - The project will utilize existing facilities and is expected to produce 200 kg of collagen annually upon completion in June 2025 [2]. Existing Project Status - The company has several ongoing projects, including: - Sodium hyaluronate project with an annual output of 50 tons [4]. - Various fermentation projects with different production capacities, including: - Recombinant Type II collagen: 115.2 kg/a - Recombinant Type XVII collagen: 64 kg/a - Recombinant Type III transmembrane collagen: 20.8 kg/a - The total annual production capacity for collagen will reach 200 kg [3][4]. Industry Events - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22, 2025, in Ningbo, Zhejiang Province, focusing on AI and bio-manufacturing, green chemicals, new materials, future food, and agriculture [8][9].

Core Viewpoint - The article highlights the approval of the "Regulations on Promoting the Development of Synthetic Biology Manufacturing Industry in Changde City," marking a significant step in the local government's efforts to foster the synthetic biology sector and establish a national-level industrial cluster [2]. Group 1: Legislative Developments - The Changde City government has prioritized the development of the synthetic biology manufacturing industry, creating a multi-faceted industrial landscape across various regions such as Jinshi City, Anxiang County, and Changde Economic Development Zone [2]. - The "Regulations" represent the first local legislation in the synthetic biology manufacturing field in China, consisting of 19 articles covering objectives, scope, government responsibilities, innovation platform construction, and more [2]. Group 2: Upcoming Events - The 4th Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on the intersection of AI and bio-manufacturing, as well as advancements in green chemicals, new materials, future food, and agriculture [4][5]. - The conference will feature various activities, including a youth forum, high-level discussions, and a closed-door seminar on the "2025 Blue Book for AI-Enabled Bio-Manufacturing Industry Innovation Development" [5].

1 # and In 大量素材料大學杭州研究 TERRET in The 实 验 金 湖 湘 XIANGHU PANI BILA © | AHT 浙江省北大信息技术高等研究院 高能级科创平台牵引下的"科创引领，数实融合"一直是萧山打破路径依赖、实现转型跃升的核心引 擎。7年时间，萧山先后打造了六大高能级科创平台，实现R&D经费投入总量从46.28亿元增长至87.05 亿元（R&D经费占GDP比重从2.57%增长至3.9%），杭州市A-E类高层次人才从437人扩大至14828人， 高新技术产业增加值占比从42.43%提高至69.07%。 案例就是路径。问及"诀窍"，萧山区科技局相关负责人表示，主要得益于处理好了"高校与政 府""高校与平台""平台与企业""平台与产业""平台与人才"的"五对关系"，同时通过"教科人一体化"改革 重塑区域创新生态，为科创新质生产力的发展营造优沃土壤。 从"补短板"到"强磁场"的七年深耕 六大高能级科创平台，是北大信息技术高等研究院、浙大杭州国际科创中心、西电杭州研究院、浙 大计算机创新技术研究院、巴顿焊接技术研究院和湘湖实验室，分别瞄准人工智能、集成电路、生物制 造、先进材料等未来 ...

Core Insights - The article emphasizes the importance of strains as the "chip" of biomass refining, highlighting their role in the new bio-manufacturing industry chain and green low-carbon bio-economy [2] - It discusses the challenges faced by strain cells in bio-manufacturing, such as the accumulation of intermediate metabolites and the inhibition of toxic products, which lead to low reaction efficiency and product concentration [2] - The article outlines key research areas, including the construction of strain cell factories and the enhancement of product synthesis processes [2] Research and Development - The research led by Professor Xue Chuang from Dalian University of Technology focuses on creating artificial organelles using multi-enzyme self-assembled protein cages, which enhance the tunability of organelles through chemical and light induction [2] - A rapid strain construction method called "multi-gun-multi-target" has been developed, revealing new mechanisms for the multidimensional cooperative regulation of strains [2] - The team has also prepared carbon nanotube array composite membranes and developed reaction separation coupling technology, providing breakthroughs in enhancing bio-synthesis of bioenergy-based products [2] Conference Participation - Professor Xue Chuang will present at the SynBioCon 2025 conference, focusing on "Cell Factory Design and Product Synthesis Enhancement" [3] - The conference will take place from August 20-22, 2025, in Ningbo, Zhejiang, and will cover topics related to AI and bio-manufacturing, green chemicals, new materials, future food, and agriculture [14][15]

Core Insights - The article highlights the successful completion of a Pre-A round financing of several million RMB by ZhiNuo Technology, a rising player in the synthetic biology field, which will enhance its production capacity, pipeline expansion, team growth, and commercialization efforts [2][3]. Company Overview - ZhiNuo Technology, established in 2020, is a national high-tech enterprise focused on synthetic biology technology, headquartered in Beijing, with R&D centers and production bases in Suzhou and Dongying, Shandong [3]. - The core team comprises interdisciplinary talents from top institutions like Oxford University and Peking University, led by Dr. Zhu Tianze, who has over a decade of experience in saccharochemistry and metabolic flow optimization [3]. Key Technological Highlights - Precision design of metabolic pathways: The company has built a microbial library covering model and non-model strains, combined with high-throughput screening and AI data analysis, which is expected to release an additional 70% efficiency potential [6]. - Rapid industrialization capability: The transition from laboratory trials to 60-ton fermentation production can be achieved in just 3-6 months, significantly shortening the cycle compared to traditional chemical processes [6]. - Multi-domain pipeline layout: ZhiNuo Technology has developed product lines worth billions to tens of billions, focusing on areas such as human milk oligosaccharides (HMOs), microbial pigments, and food-grade functional ingredients, covering industries like dyeing, daily chemicals, human health, and modern agriculture [6].

Core Viewpoint - The article emphasizes that biomanufacturing is becoming a key engine for the transformation and upgrading of the chemical industry, driven by the global green transition and "dual carbon" goals [2]. Group 1: Biomanufacturing and Chemical Industry Transformation - Biobased materials, derived from renewable biomass such as starch, cellulose, and fats, are fundamentally changing the linear economic model of "mass production, mass consumption, and mass waste" through a circular economy approach [2]. - Synthetic biology and biomanufacturing utilize biomass as raw materials, leveraging the metabolic functions of microorganisms, cells, and enzymes to achieve large-scale production of target products [3]. - Key pathways for the green transformation of the chemical industry include the development of non-food biobased synthetic products, green biomanufacturing of plastic monomers like dicarboxylic acids and diols, utilization and conversion of one-carbon resources like CO2, and enzymatic recycling of waste plastics [3]. Group 2: Upcoming Conference and Expert Participation - The Fourth Synthetic Biology and Green Biomanufacturing Conference will be held from August 20-22 in Ningbo, Zhejiang, featuring a session on green chemicals and new materials with participation from prominent experts and representatives from biomanufacturing companies [4]. - Notable speakers include Professor Wang Dan from Chongqing University, Professor Xue Chuang from Dalian University of Technology, and Yang Shihui, founder of Wuhan Ruijia Kang, who will discuss various aspects of biomanufacturing and its applications [6][7]. Group 3: Conference Agenda Highlights - The conference will include discussions on cell factory design, microbial cell factories for plastic monomers, and green separation and purification technologies in synthetic biology [30][35]. - A special focus will be on the application of non-food biomass sugars in synthetic biology and green biomanufacturing, showcasing flexible production platforms [7]. - The agenda also features a series of forums on AI empowerment in biomanufacturing and future food and agriculture innovations [14][43]. Group 4: Industry Collaboration and Research - The conference is organized by DT New Materials in collaboration with various academic and research institutions, highlighting the importance of industry-academia partnerships in advancing biomanufacturing technologies [10][16]. - The event aims to promote the sharing of innovative research and practical applications in the field of biomanufacturing, contributing to the overall growth of the industry [39].

Group 1: Technological Innovations - The Beijing Huairou Science City has developed the High Energy Photon Source (HEPS), which emits light 10 trillion times brighter than the sun, enabling detailed analysis of molecular structures and contributing to original innovations [1][2] - The EAST nuclear fusion experiment in Hefei achieved a world record of 100 million degrees Celsius for 1000 seconds, marking a significant step towards fusion power generation [2] - Shenzhen's agricultural drones utilize proprietary rotor drive technology and have secured over 600 patents, with the low-altitude economy in Guangdong exceeding 100 billion yuan [4] Group 2: Industry and Economic Impact - The integration of technology and industry is creating a new engine for high-quality development, with the approval of a low-calorie sweetener, alulose, showcasing rapid market transformation of new technologies [5][6] - The automotive industry in Anhui has become a leader in production, with both traditional and new energy vehicles ranking first in the country as of May 2023 [4] - The Beijing-Tianjin-Hebei region's collaboration in the automotive supply chain has led to a 154% year-on-year increase in new energy vehicle production [7] Group 3: Talent and Innovation Ecosystem - The Huairou Science City attracts top global talent, fostering an environment conducive to innovation and collaboration among researchers [3] - The establishment of the XbotPark robotics base in Dongguan exemplifies the successful collaboration between Hong Kong and mainland scientists, creating a robust innovation ecosystem for robotics [8] Group 4: Regional Collaboration - The Greater Bay Area has developed a "technology innovation corridor," facilitating efficient resource flow and collaboration among various regions [8] - The integration of innovation resources across regions is essential for enhancing productivity and achieving breakthroughs in technology and industry [7][9]

Core Viewpoint - The article highlights the rapid growth of metabolic diseases due to modern lifestyle factors and emphasizes the potential of functional sugars as dietary regulators to alleviate gut microbiota imbalance [2]. Group 1: Functional Sugars Market - The global functional sugars market is experiencing rapid growth, but there is significant product homogeneity and challenges in obtaining new functional sugars with specific structures and targeted regulation [2]. - The difficulties stem from unclear mechanisms of action, unknown biosynthetic pathways, and low levels of intelligent manufacturing in large-scale production [2]. Group 2: Research and Development - Professor Wu Jing's team at Jiangnan University has made advancements in the green biomanufacturing of various functional sugars, including allulose, tagatose, lactulose, resistant dextrin, and human milk oligosaccharides [2]. - These developments are crucial for creating health-oriented dietary regulators for the general public and align with the "Healthy China" strategic planning [2]. Group 3: Upcoming Conference - Professor Wu Jing will present at the SynBioCon 2025 conference, scheduled for August 20-22 in Ningbo, focusing on the topic of "Exploration and Green Biomanufacturing of New Functional Sugars" [2][9]. - The conference will cover topics related to AI and biomanufacturing, green chemicals, new materials, future food, and agriculture [9][10].