2025年8月20-22日，第四届合成生物与绿色生物制造大会（SynBioCon 2025）于浙江宁波召开。这场以"生物制造赋能未来"为核心的行业峰会， 汇聚了全球顶尖科研机构与产业领袖。 中国健康食用油领域的突破者—— 轻云减负油 ，凭借" 生物科技重构油脂产业 "的创新实践成为焦点。其 联合创始人兼CTO贺林博士 受邀发表主题 演讲， 公布与北京大学医学部合作的百人规模甘油二酯（DAG）临床研究成果 ，以硬核数据宣告 ：合成生物技术正推动食用油产业进入"代谢减负时 代" 。 技术破局：生物酶解重构油脂分子 从 "易囤积"到"代谢友好"的进化 传统食用油的加工理念通常可概括为 "提高纯度，牺牲营养"。这类油通过高温精炼工艺去除杂质，却也在这一过程中破坏了油脂中的天然活性成分。 此外，传统油脂中甘油三酯（TAG）"易囤积的脂肪"含量超过95%，其代谢需经肠壁吸收进入血液循环，最终以脂肪形式储存于体内。长期过量摄入易 引发脂肪堆积和胰岛素抵抗。相比之下，生物技术所倡导的油脂加工逻辑更倾向于"精准改造，保留精华"。 以轻云减负油为例，该产品依托自主研发的 生物酶解工艺 ，在低温条件下将天然甘油三酯转化为 甘油二酯 ...

Core Viewpoint - The collaboration between Shanghai Zhiyu Biotechnology, Nanjing Normal University, and Changzhou Beiliguan Biotechnology aims to innovate and industrialize the production of taurine using a biocatalytic method, contributing to a green industry chain driven by synthetic biology [2][3][5]. Group 1: Collaboration Details - The partnership involves three parties: Zhiyu Biotechnology will focus on the core process development for biocatalytic taurine production, ensuring technological leadership and innovation [5]. - Nanjing Normal University will handle pilot-scale testing and technical validation to ensure stable experimental conditions and reliable results [5]. - Changzhou Beiliguan will provide market insights, focusing on market research, channel development, and promotion to facilitate the commercialization of the technological outcomes [5]. Group 2: Taurine Overview - Taurine is a significant ingredient in functional beverages and health products, with its green and efficient production technology being a focal point of industry interest [6]. - As a β-amino acid and a derivative of cysteine, taurine is abundant in various tissues in the human body and is widely used in pharmaceuticals and food sectors for its nutritional enhancement, immune support, and fatigue relief properties [6]. - The biosynthesis of taurine primarily occurs through a series of enzymatic reactions involving cysteine, leading to its final form, which is crucial for various physiological functions [6].

Core Viewpoint - The establishment of the China-Malaysia joint laboratory for oil processing and safety marks a significant collaboration under the Belt and Road Initiative, aimed at advancing key technologies in the oil industry and promoting sustainable development [1][2]. Group 1: Joint Laboratory Overview - The joint laboratory is the first of its kind between China and Malaysia, co-established by Jinan University and Universiti Putra Malaysia, serving as a national-level technology innovation platform [1]. - The laboratory focuses on four main research areas: oil bio-processing and safety, extraction of bioactive lipid molecules and their health effects, applications of healthy oils and functional foods, and the sustainability of the palm oil supply chain [1]. Group 2: Research Directions and Goals - The laboratory aims to transform palm oil from Malaysia into more nutritious and healthy glycerol diesters, representing the future of healthy oils, through methods like bio-processing and synthetic biology [1]. - Research will also focus on extracting active components such as beta-carotene from structural lipids to study their anti-inflammatory, anti-osteoporosis, and anti-cancer mechanisms, with plans to develop functional products [1]. - Collaboration with the School of Pharmacy at Jinan University will explore lipid bio-molecules from Malaysian medicinal plants [1]. Group 3: Bilateral Trade Context - By 2025, China and Malaysia will celebrate the 51st anniversary of diplomatic relations and the 12th anniversary of their comprehensive strategic partnership [2]. - China imports approximately 28 million tons of oils annually, while Malaysia exports about 15 million tons of palm oil, indicating a highly complementary supply-demand structure between the two countries [2].