N Health旨在强化其在提供端到端医疗保健解决方案方面的角色，同时通过战略伙伴关系在全国范围内 扩大先进癌症筛查的可及性，亦将使N Health能够将先进的癌症风险评估整合至预防保健中，从而在泰 国过度至老龄化社会的过程中支持早期干预并促进更健康的老龄化过程。此外，战略伙伴关系将改变泰 国癌症的识别与管理方式，同时为本公司在整个东南亚的成长铺路。 来源：智通财经网 MIRXES-B(02629)发布公告，本公司已于2025年12月15日与N Health (N Health，为一家医疗保健解决方 案供应商及泰国最大医疗保健供应商Bangkok Dusit Medical Services (BDMS) Group的成员公司)建立战 略伙伴关系。战略伙伴关系旨在将先进的microRNA (miRNA)癌症筛查解决方案引进泰国，并标志着泰 国及更广泛地区在加强早期癌症检测及改善患者疗效方面向前迈进了一大步。 战略伙伴关系进军泰国体检市场，该市场正经历大幅增长。预期到2030年，泰国的体检市场规模将达到 约5亿美元，自2025年起复合年增长率为9.2%，其专科体检为增长最快的分部，显示对先进且具针对性 的筛查解 ...

粪便隐血检测被广泛用作结直肠异常的前线筛查方法，而幽门螺桿菌感染则属胃部疾病(特别是胃癌)的 既定风险因素。这两项指标亦与胃肠疾病密切相关，且被公认为早期检测胃癌及结直肠癌的重要指标。 这些居家检测试剂盒可让患者及早发现癌症，并鼓励患者及时就医，为重要的首选筛查工具，与本公司 更广泛的早期癌症检测生态系统(包括先进分子诊断技术)相辅相成。 为确保广泛的可及性，本公司将透过泰国各地的现代贸易通路及药房网路分销这些检测试剂盒，以符合 消费者不断演变的医疗保健行为以及对预防性、自助式诊断日益增加的需求。产品的推出强调本公司早 期检测民主化的使命，让个人拥有实用的工具来掌控自身的健康，同时透过早期介入及提高疾病意识以 支持医疗保健系统。这亦为本公司长期战略中的一项重要里程碑，该战略旨在将早期癌症检测扩展至医 院及实验室之外，使可靠的筛查解决方案能够在日常消费环境中得到应用。 N Health旨在强化其在提供端到端医疗保健解决方案方面的角色，同时通过战略伙伴关系在全国范围内 扩大先进癌症筛查的可及性，亦将使N Health能够将先进的癌症风险评估整合至预防保健中，从而在泰 国过度至老龄化社会的过程中支持早期干预并促进更 ...

格隆汇1月9日丨MIRXES-B(02629.HK)发布公告，公司已于2025年12月15日与N Health("N Health"，为 一家医疗保健解决方案供应商及泰国最大医疗保健供应商Bangkok Dusit Medical Services (BDMS) Group 的成员公司)建立战略伙伴关系。战略伙伴关系旨在将先进的microRNA (miRNA)癌症筛查解决方案引进 泰国，并标志着泰国及更广泛地区在加强早期癌症检测及改善患者疗效方面向前迈进了一大步。 随着泰国FDA分别于2025年10月及2025年12月授出批准，公司已于2026年1月9日在泰国推出新系列的居 家筛查检测试剂盒，即HELICORapid(专为检测幽门螺旋杆菌(H. pylori)感染而设，而幽门螺旋杆菌为已 知可诱发胃癌的主要和重大成因)及FITRapid(专为检测大便隐血而设，而大便隐血是结肠或直肠癌症或 息肉的指标)。这两项直接面向消费者的癌症风险因素检测旨在补充及协同公司的核心创新miRNA癌症 筛查解决方案(包括泰国FDA批准的GASTROClear™及其管线中的结直肠癌及多癌种血液检测)，并使公 司能够将其销售及营销工 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或依 賴該等內容而引致的任何損失承擔任何責任。 Mirxes Holding Company Limited （ 於 開 曼 群 島 註 冊 成 立 的 有 限 責 任 公 司 ） （股份代號：2629） 自願性公告 於泰國的近期業務發展進程 本公告乃由Mirxes Holding Company Limited（「本公司」，連同其附屬公司統稱「本 集團」）自願刊發，旨在知會本公司股東及潛在投資者有關本集團的最新業務 發展。 與N HEALTH建立戰略夥伴關係 本公司董事（「董事」）會（「董事會」）宣佈，本公司已於2025年12月15日與N Health （「N Health」，為 一 家 醫 療 保 健 解 決 方 案 供 應 商 及 泰 國 最 大 醫 療 保 健 供 應 商 Bangkok Dusit Medical Services (BDMS) Group的成員公司）建立戰略夥伴關係（「戰 略夥伴關係」）。戰略夥伴關係旨在將先進的microRN ...

Major Events - MIRXES-B (02629) received approval from the National Medical Products Administration of China for the GASTROClear™ IVD registration certificate for gastric cancer screening [1] - JD Logistics (02618) plans to acquire JD Group's local instant delivery service business for $270 million to enhance "last mile" delivery capabilities [1] - HSBC Holdings (00005) intends to privatize Hang Seng Bank (00011) [1] - Fuhong Hanlin (02696) reported that the phase III clinical study of Hansu® (sulizumab injection) in combination with chemotherapy for neoadjuvant/adjuvant treatment of gastric cancer achieved its primary endpoint [1] - WuXi AppTec (02126) announced that the National Medical Products Administration officially accepted the supplementary application for the post-marketing use of Benodda® with a domestic viral vector [1] - Sunny Optical (02382) plans to transfer approximately 1.903 billion yuan to Shanghai Aolai and invest in GoerTek to jointly develop AI/AR optical business [1] - CSPC Pharmaceutical Group (01093) received clinical trial approval for SYH2070 injection (double-stranded small interfering RNA drug) in the United States [1] - Yanda Pharmaceutical (00512) completed patient enrollment for the registration clinical study of a globally innovative temperature-sensitive embolic agent in China [1] - CloudWalk Technology (09678) successfully won bids for multiple intelligent agent projects, including the AI capability platform for Beijing Friendship Hospital [1] - Huakang Biomedical (08622) received a cash offer from Anselme Limited to acquire 27.71% of its shares at a discount of approximately 68.10%, with resumption of trading on October 10 [1] Operating Performance - Baolong Properties (01238) reported a total contracted sales of approximately 5.431 billion yuan in the first nine months, a year-on-year decrease of 43.64% [2] - Fast Retailing (06288) released its annual performance, with a net profit attributable to shareholders of 433.009 billion yen, a year-on-year increase of 16.4%, with trading resuming on October 10 [2] - Jingrui Holdings (01862) reported a contracted sales amount of 740 million yuan in the first nine months, a year-on-year decrease of 49.52% [2] - Dongfeng Motor Group (00489) recorded cumulative automobile sales of 1.3168 million units in the first nine months, a year-on-year decline of approximately 3.6% [2] - Yaoshi Bang (09885) reported a total transaction volume of approximately 658.4 million yuan for its brand promotion business in the third quarter, a year-on-year increase of 163% [2]

Market Performance - The Hang Seng Index closed down 0.48% at 26,829.46 points, with the Hang Seng Tech Index down 0.55% and the Hang Seng China Enterprises Index down 0.52%[1] - The total market turnover was HKD 173.8 billion[1] - In contrast, European indices closed higher, and the S&P 500 rose by 0.58% while the Nasdaq increased by 1.12%[1] Federal Reserve Insights - The Federal Reserve's meeting minutes indicated a cautious approach to interest rate cuts due to inflation concerns, with a majority of officials suggesting further easing may be appropriate this year[12] - The Federal Funds rate was lowered by 25 basis points to a range of 4% to 4.25%, marking the first cut of the year[12] Currency Movements - The Japanese yen reached an eight-month low against the US dollar, nearing the critical psychological level of 155[12] - Observers are considering the risk of intervention by Japanese authorities if the yen continues to weaken[12] Geopolitical Developments - Former President Trump announced that Israel and Hamas reached an agreement on the first phase of a peace plan, which includes the release of hostages and the withdrawal of Israeli troops[12] Corporate Actions - HSBC's CEO stated that a 30% premium for privatizing Hang Seng Bank is an attractive offer, emphasizing the potential for growth in Hong Kong[14] - Zijin Mining International exercised its over-allotment option, raising approximately RMB 3.747 billion through the issuance of additional shares[14]

Core Viewpoint - MIRXES-B (02629.HK) has received approval from the National Medical Products Administration of China for its core product GASTROClear™, marking it as the first blood test approved for non-invasive gastric cancer screening in China [1] Product Approval - GASTROClear™ is the world's first microRNA blood test approved for early detection of gastric cancer, assessing cancer risk by detecting 12 gastric cancer-related miRNA biomarkers [1] - The product was previously approved in Singapore in 2019 and received "breakthrough device" designation from the FDA in 2023 [1] Significance of Approval - The approval in China represents a significant milestone for the company, indicating a successful transition from research and development to commercialization [1] - This achievement reflects the company's long-term commitment and investment in technological innovation and large-scale clinical trials [1]

Core Insights - MIRXES-B's core product GASTROClear™ has received approval from the National Medical Products Administration of China for Class III medical device registration, marking it as the first blood test approved for non-invasive gastric cancer screening in China [1] - GASTROClear™ is the world's first microRNA blood test approved for early detection of gastric cancer, assessing cancer risk by detecting 12 gastric cancer-related miRNA biomarkers [1] - The approval allows GASTROClear™ to be used for screening high-risk adults aged 45-74, potentially covering over 500 million people in China [1] Company Strategy - The company plans to continue expanding its commercialization efforts in China, including increasing the size of its sales team and upgrading local production capabilities [2] - The company aims to strengthen its business development and collaboration efforts in mainland China to promote wider adoption of its products [2]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內容而產生或依 賴該等內容而引致的任何損失承擔任何責任。 本公告乃由Mirxes Holding Company Limited（「本公司」，連同其附屬公司統稱「本 集團」）自願刊發，旨在知會本公司股東及潛在投資者有關本集團最新業務發展。 本公司董事（「董事」）會（「董事會」）欣然宣佈，其核心產品GASTROClear™已獲 得中國國家藥品監督管理局（「國家藥監局」）批准第三類醫療器械注冊證，作 為體外診斷（「IVD」）產品在中國用於非侵入性胃癌篩查。該款產品為首款獲國 家藥監局批准用於胃癌篩查的血液檢測。 GASTROClear™為全球首個獲批用於胃癌早期檢測的微小核酸(miRNA)血液檢 測方法，通過檢測12種胃癌相關miRNA標誌物評估胃癌風險。此前，該產品已 於2019年在新加坡獲批，並於2023年獲美國食品藥物管理局（「FDA」）「突破性 器械」認定。此次在中國獲國家藥監局批准，標誌著本公司完成了從研發到商 業化的重要跨越，也體現了其在技術創新、大規模臨 ...

Core Viewpoint - The mid-term performance of Mirxes Holding Company Limited demonstrates its commercial capabilities in the field of early cancer screening [1] Financial Performance - For the first half of 2025, Mirxes achieved revenue of $10.5 million, a 9.4% increase compared to the same period in 2024, driven by a 50% growth in the early detection and precision multi-omics segment, which now accounts for 100% of the company's revenue [4] - The gross profit for this segment reached $7.1 million, reflecting a 102.9% year-on-year increase [4] - The gross margin improved from 49.0% to 67.6%, with gross profit increasing by 51.1% [5][6] - The company reported a significant reduction in losses, down 36.3% to $28.23 million, aided by effective cost management [6] Market Expansion and Strategic Partnerships - Mirxes has engaged in strategic partnerships to enhance its market presence, including a nationwide early screening project in Japan and a memorandum of understanding with PT DIASTIKA BIOTEKINDO in Indonesia [4] - The company’s flagship product, GASTROClear™, has received regulatory approval in Singapore and Thailand, and has been recognized as a "breakthrough medical device" by the FDA in the U.S. [6] Product Development and Future Outlook - The company is advancing its product pipeline, with plans for the CRC-1 colorectal cancer detection product to complete prototype design in the second half of this year and initiate clinical trials in Singapore and China in 2026 [7] - The CEO emphasized the company's commitment to accelerating the global registration process for core products and expanding its product pipeline through a multi-omics technology platform [7]