EF001 | 公告全部或任何部份內容而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 | 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦不發表任何聲明，並明確表示，概不對因 | | --- | --- | | | 股票發行人現金股息公告 | | 發行人名稱 | China Medical System Holdings Limited 康哲藥業控股有限公司* (*僅供識別) | | 股份代號 | 00867 | | 多櫃檯股份代號及貨幣 | 不適用 | | 相關股份代號及名稱 | 不適用 | | 公告標題 | 截至二零二五年六月三十日止六個月之中期股息 | | 公告日期 | 2025年8月18日 | | 公告狀態 | 新公告 | | 股息信息 | | | 股息類型 | 中期（半年期） | | 股息性質 | 普通股息 | | 財政年末 | 2025年12月31日 | | 宣派股息的報告期末 | 2025年6月30日 | | 宣派股息 | 每 股 0.1555 RMB | | 股東批准日期 | 不適用 | | 香港過戶登記處相關信息 | | | 派息金額及公司預 ...

*僅供識別 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦 不發表任何聲明，並表明概不就因本公告全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失 承擔任何責任。 CHINA MEDICAL SYSTEM HOLDINGS LIMITED 康 哲 藥 業 控 股 有 限 公 司 * （於開曼群島註冊成立的有限公司） （香港股份代號：867） （新加坡股份代號：8A8） 截至二零二五年六月三十日止六個月之中期業績公告及非執行董事辭任 China Medical System Holdings Limited（「本公司」）之董事會（「董事會」）欣然公佈本公司及其附屬 公司（「本集團」或「康哲藥業」）截至二零二五年六月三十日止六個月(「報告期」)之未經審計簡明 合併業績。 財務摘要 1 營業額同比增長 10.8%至人民幣 4,002.0 百萬元（二零二四年中期：人民幣 3,611.1 百萬元）；若全 按藥品銷售收入計算則營業額同比增長 8.9%至人民幣 4,669.6 百萬元（二零二四年中期：人民幣 4,287.5 百萬元） 毛利同比增長 7.2%至人民幣 2,8 ...

Core Insights - Chinese pharmaceutical companies are transitioning from "followers" to "leaders" in the global market, particularly focusing on Southeast Asia as a new growth area [1][3] - The recent secondary listing of Kangzhe Pharmaceutical on the Singapore Exchange marks a significant step in its internationalization strategy, aiming to leverage Southeast Asia's vast market potential [1][3][10] Market Expansion Strategies - Kangzhe Pharmaceutical is utilizing Singapore as a strategic hub to access the Southeast Asian pharmaceutical market, which has over 600 million people [3][10] - The company has established a comprehensive business ecosystem in Singapore, covering research, production, and sales, to enhance operational efficiency and market responsiveness [8][10][12] Challenges and Solutions - The company faces challenges such as fragmented regulations in emerging markets, varying payment capabilities, and differing healthcare needs across countries [5][6] - To address these challenges, Kangzhe Pharmaceutical has implemented localized registration strategies and established dedicated teams with extensive local experience [5][8] Product Focus and Innovation - Kangzhe Pharmaceutical is concentrating on specialized fields such as dermatology and ophthalmology, aiming to become a leader in niche markets rather than competing in saturated areas like oncology [13][14] - The company has a robust pipeline of approximately 40 innovative products, with a focus on high-quality, cost-effective solutions tailored to local market needs [14][17] Future Outlook - The company has invested over $100 million in the Southeast Asian and Middle Eastern markets over the past three years, indicating a strong commitment to expanding its footprint in these regions [10] - Kangzhe Pharmaceutical aims to leverage its established R&D capabilities and cost advantages from the Chinese market to enhance its product offerings in Southeast Asia [16][17]

Investment Rating - The industry investment rating is "Outperform the Market" [1][47]. Core Insights - The white spot market for vitiligo treatment is vast, with a potential market size expected to reach 21.7 billion yuan by 2030, driven by an increasing number of patients and the need for effective treatments [3][15][39]. - Current treatment options are inadequate, with no approved products specifically for vitiligo in China, highlighting a significant gap in the market that innovative drugs could fill [3][26]. - The competitive landscape is favorable, with several small pharmaceutical companies and leading firms vying for market share, and key products expected to receive approval soon [3][39]. Summary by Sections Part 1: Patient Demographics and Health Risks - The prevalence of vitiligo is significant, with approximately 22.83 million patients in China, of which 54.01% are receiving treatment [3][15]. - The condition is associated with severe psychological impacts, including a higher incidence of depression among patients [3][10]. Part 2: Current Treatment Limitations - Existing treatments, primarily involving drug therapy and phototherapy, have shown limited effectiveness, necessitating the introduction of new drugs with higher repigmentation rates [3][24]. - The current market lacks approved medications specifically for vitiligo, with existing drugs primarily approved for other conditions [3][26]. Part 3: Competitive Landscape and Drug Development - The vitiligo treatment sector is characterized by a lack of approved products, with several drugs in various stages of clinical trials, including one in Phase III and six in Phase II [3][39]. - JAK inhibitors are identified as key targets in drug development, with the first approved topical JAK1/JAK2 inhibitor, Ruxolitinib cream, showing promising sales growth [3][32][39]. - The innovative drug market for vitiligo is projected to reach 10 billion yuan, with significant interest in companies like Kangzheng Pharmaceutical and TianKang [3][39]. Part 4: Investment Recommendations - The report suggests focusing on the progress of drug development in the vitiligo sector and monitoring companies involved, including Kangzheng Pharmaceutical, TianKang, Huadong Medicine, and others [3][39].

Group 1 - The company, Kangzheng Pharmaceutical (00867.HK), has announced a board meeting scheduled for August 18, 2025, to consider and approve the interim results for the six months ending June 30, 2025 [1] - The board meeting will also consider the distribution of an interim dividend, if applicable [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其 準確性或完整性亦不發表任何聲明，並表明概不就因本公告全部或任何部分內容而產生 或因倚賴該等內容而引致的任何損失承擔任何責任。 香港，二零二五年八月六日 於本公告日期，本公司董事包括 (i) 執行董事：林剛先生及陳燕玲女士； (ii) 非執行董事： 陳洪兵先生； (iii) 獨立非執行董事：梁創順先生、羅瑩女士及馮征先生。 *僅供識別 1 董事會會議通告 China Medical System Holdings Limited（「本公司」）董事會（「董事會」）茲通告，本公 司謹定於二零二五年八月十八日（星期一）召開本公司董事會會議，其中包括考慮及擬 批准本公司及其附屬公司截至二零二五年六月三十日止六個月之中期業績，及考慮派發 中期股息（如有）。 承董事會命 China Medical System Holdings Limited 主席 林剛 ...

Group 1 - The core viewpoint is that the liquidity and fundamentals of the Chinese healthcare industry continue to improve, maintaining a positive outlook for the healthcare sector [1] - The report indicates that the weak U.S. employment data may lead to heightened expectations for monetary easing in the second half of the year, suggesting an improved outlook for the industry [1] - The report highlights that the industry fundamentals are recovering, with a month-on-month increase in hospital prescription volumes in July, and significant profit growth expected in the third quarter due to the release of more innovative drugs [1] Group 2 - The company prefers leading large pharmaceutical firms and suggests avoiding companies overly reliant on biosimilars in the short term [2] - Selected stocks include: CSPC Pharmaceutical Group (01093), Sinopharm Group (01099), Hansoh Pharmaceutical (03692), and others [2] - The report emphasizes that the uncertainty in U.S. Treasury yields may prompt a reallocation of funds, further improving the liquidity of innovative drug assets [1]

里昂指出，行业基本面持续复苏，7月院内处方量环比提升，随着更多创新药放量，第三季行业盈利有 望实现显著增长，加上美债不确定性可能促使资金重新配置，进一步改善创新药资产流动性，相信行业 拐点已过，未来将迎来盈喜等正面催化剂。 该行偏好领先大型药厂，短期而言避开过度依赖生物仿制药的公司。该行选股包括石药集团(01093)、 新诺威(300765.SZ)、翰森制药(03692)、爱尔眼科(300015.SZ)、恒瑞医药(01276,600276.SH)、康方生物 (09926)、中生制药(01177)、国药控股(01099)、康哲药业(00867)、大参林(603233.SH)、华东医药 (000963.SZ)、泰格医药(03347)及药明康德(02359)。 智通财经APP获悉，里昂发布研报称，中国医疗健康行业流动性及基本面持续改善，维持对医疗健康板 块正面看法，指出美国就业数据疲软或市场对下半年货币宽松预期急升温，预示着行业下半年改善前 景，相信特朗普再提最惠国药品定价政策及安徽启动生物类似药集中采购，对行业影响则相对有限。 ...

截至月份: 2025年7月31日 狀態: 新提交 FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 致：香港交易及結算所有限公司 公司名稱: China Medical System Holdings Limited 康哲藥業控股有限公司*（*僅供識別） 呈交日期: 2025年8月1日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 00867 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 20,000,000,000 | USD | USD | 0.005 | | 100,000,000 | | 增加 / 減少 (-) | | | | | | USD | | | | 本月底結存 | | | 20,000,000,000 | USD | ...

| 股份代號: | 00867 | | --- | --- | | 上市法國名稱: | 康哲藥業控股有限公司 | | 日期 (日 / 月 / 年): | 01/07/2025 - 01/08/2025 | 格隆汇8月1日丨根据联交所最新权益披露资料显示，2025年7月29日，康哲药业(00867.HK)遭Lazard Asset Management LLC在场内以每股均价13.7518港元减 持774.2万股，涉资约1.06亿港元。 减持后，Lazard Asset Management LLC最新持股数目为121,070,000股，持股比例由5.28%下降至4.96%。 | 麦格序號 | 大股東/董事/最高行政人員名稱作出披露的 買入 / 費出或涉及的 每股的平均價 | | | | 持有權益的股份數目 佔已發行的 有關事件的日期 | | | --- | --- | --- | --- | --- | --- | --- | | | 時代言 | | | | (語参照上述 * 註 有投票權股 (日 / 月 / 年) | | | | | | | | | 防信分同 | | | | | | | | 961 | | ...