Core Viewpoint - Shanghai Pharmaceuticals announced that its subsidiary, Shanghai Shenyang Pharmaceutical Co., Ltd., successfully negotiated to include Amisulpride orally disintegrating tablets in the National Medical Insurance Directory, effective from January 1, 2026, to December 31, 2027 [1] Group 1 - Amisulpride orally disintegrating tablets are an improved formulation of Amisulpride tablets, which were launched by Sanofi in France in 1986, and are used for the treatment of adult schizophrenia [1] - As of the announcement date, there are no other companies in China that have launched Amisulpride orally disintegrating tablets [1] - Shanghai Shenyang Pharmaceutical Co., Ltd. became the marketing authorization holder for Amisulpride orally disintegrating tablets after receiving approval from the National Medical Products Administration in October 2025 [1]

Core Viewpoint - Shanghai Pharmaceuticals has successfully included its amisulpride orally disintegrating tablets in the National Medical Insurance Directory, effective January 1, 2026, which is expected to enhance market share and competitiveness [1] Group 1: Company Information - Shanghai Pharmaceuticals' subsidiary, Shanghai Shiyou Zhongxi Pharmaceutical Co., Ltd., has obtained the marketing authorization for amisulpride orally disintegrating tablets [1] - The amisulpride orally disintegrating tablets are a modified formulation of amisulpride tablets originally launched by Sanofi in France in 1986, used for treating adult schizophrenia [1] - As of the announcement date, there are no other companies in China that have launched amisulpride orally disintegrating tablets [1] Group 2: Market Impact - The inclusion of amisulpride orally disintegrating tablets in the National Medical Insurance Directory is expected to expand the product's market share and improve its competitive position [1] - According to the IQVIA database, the hospital procurement amount for amisulpride oral formulations in 2024 is projected to be RMB 168.41 million [1] - The successful negotiation for inclusion in the insurance directory will provide valuable experience for the company in promoting other products [1]

Core Viewpoint - Shanghai Pharmaceuticals has successfully included its amisulpride orally disintegrating tablets in the National Medical Insurance Directory, effective January 1, 2026, which is expected to enhance market share and competitiveness [1] Group 1: Company Information - Shanghai Pharmaceuticals' subsidiary, Shanghai Shiyou Zhongxi Pharmaceutical Co., Ltd., has obtained the listing rights for amisulpride orally disintegrating tablets [1] - The amisulpride orally disintegrating tablets are a modified formulation of the amisulpride tablets launched by Sanofi in France in 1986, used for treating adult schizophrenia [1] - As of the announcement date, there are no other companies in China that have launched amisulpride orally disintegrating tablets [1] Group 2: Market Impact - The inclusion of amisulpride orally disintegrating tablets in the National Medical Insurance Directory is expected to expand the product's market share and improve its competitive position [1] - According to the IQVIA database, the hospital procurement amount for amisulpride oral formulations in 2024 is projected to be RMB 168.41 million [1] - The successful negotiation for inclusion in the insurance directory will provide valuable experience for the company in promoting other products [1]

Core Viewpoint - Shanghai Pharmaceuticals (02607.HK) announced that its drug, Amisulpride Orally Disintegrating Tablets, has been successfully included in the National Medical Insurance Catalog, effective from January 1, 2026, following negotiations with the National Healthcare Security Administration and the Ministry of Human Resources and Social Security [1] Group 1: Drug Information - Amisulpride Orally Disintegrating Tablets is a modified formulation of Amisulpride, originally launched by Sanofi in France in 1986, used for treating adult schizophrenia [1] - Shanghai Pharmaceuticals' subsidiary, Shanghai Shiyou Zhongxi Pharmaceutical Co., Ltd., became the marketing authorization holder for Amisulpride Orally Disintegrating Tablets after approval from the National Medical Products Administration in October 2025 [1] - As of the announcement date, there are no other companies in China that have listed Amisulpride Orally Disintegrating Tablets [1] Group 2: Market Data - According to the IQVIA database, the hospital procurement amount for Amisulpride oral formulations in 2024 is projected to be RMB 168.41 million [1]

香港交易及結算所有限公司和香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或因依賴 該等內容而引致的任何損失承擔任何責任。 上 海 醫 藥 集 團 股 份 有 限 公 司 本公告乃根據香港聯合交易所有限公司證券上市規則第 13.10B 條而作出。 茲載列上海醫藥集團股份有限公司（「本公司」）在上海證券交易所網站(http://www.sse.com.cn) 刊登的《上海醫藥集團股份有限公司關於氨磺必利口崩片通過國家醫保談判並成功納入國家 醫保目錄的公告》僅供參閱。 承董事會命 上海醫藥集團股份有限公司 楊秋華 董事長 中國上海，2025 年 12 月 9 日 於本公告日期，本公司的執行董事為楊秋華先生、沈波先生、李永忠先生及董明 先生；非執行董事為張文學先生；以及獨立非執行董事為顧朝陽先生、霍文遜先 生、王忠先生及萬鈞女士。 * 僅供識別 Shanghai Pharmaceuticals Holding Co., Ltd. * （於中華人民共和國註冊成立的股份有限公司） （股份代碼：02607） 海外監管公告 关于氨磺必利口 ...

Core Viewpoint - Shanghai Pharmaceuticals (601607.SH) announced that its product, Amisulpride Orally Disintegrating Tablets, has been successfully included in the National Medical Insurance Directory, effective January 1, 2026, following negotiations with the National Healthcare Security Administration and the Ministry of Human Resources and Social Security [1] Group 1 - The National Medical Insurance Directory for 2025 was published on December 7, 2025, by the National Healthcare Security Administration and the Ministry of Human Resources and Social Security [1] - The Amisulpride Orally Disintegrating Tablets are a modified formulation of the original Amisulpride Tablets launched by Sanofi in France in 1986, used for treating adult schizophrenia [1] - Shanghai Pharmaceuticals' subsidiary, Shanghai Shiyou Zhongxi Pharmaceutical Co., Ltd., became the marketing authorization holder for Amisulpride Orally Disintegrating Tablets after approval from the National Medical Products Administration in October 2025 [1]

证券代码：601607 证券简称：上海医药 编号：临 2025-112 上海医药集团股份有限公司 关于氨磺必利口崩片通过国家医保谈判并 成功纳入国家医保目录的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 2025 年 12 月 7 日，国家医保局、人力资源社会保障部发布《国家基本医疗 保险、生育保险和工伤保险药品目录（2025 年）》（以下简称"《国家医保目 录》"），自 2026 年 1 月 1 日起执行。上海医药集团股份有限公司（以下简称 "公司"）下属上海上药中西制药有限公司（以下简称"上药中西"）的氨磺必 利口崩片（以下简称"该药品"） 通过国家医保谈判，成功纳入《国家医保目 录》。具体情况如下： 一、该药品基本情况 药品名称：氨磺必利口崩片 剂型：片剂 规格：50mg、0.2g 注册分类：化学药品 药品批准文号：国药准字 H20250041、国药准字 H20250042 协议有效期：自 2026 年 1 月 1 日至 2027 年 12 月 31 日 截至本公告日，中国境内氨磺必利口崩片暂无其他企业上市 ...

Core Viewpoint - Shanghai Pharmaceuticals (601607.SH) announced that its subsidiary, Shanghai Shiyou Zhongxi Pharmaceutical Co., Ltd., has successfully negotiated to include Amisulpride orally disintegrating tablets in the National Medical Insurance Directory, effective from January 1, 2026, to December 31, 2027 [1] Group 1 - Amisulpride orally disintegrating tablets are a modified formulation of Amisulpride tablets, which were launched by Sanofi in France in 1986, and are used for the treatment of adult schizophrenia [1] - As of the date of the announcement, there are no other companies in China that have listed Amisulpride orally disintegrating tablets [1] - According to the IQVIA database, the hospital procurement amount for Amisulpride oral formulations in 2024 is projected to be 168 million yuan [1]

Core Viewpoint - Shanghai Pharmaceuticals (601607) announced that its subsidiary, Shanghai Pharmaceuticals Zhongxi, has successfully negotiated for the inclusion of Amisulpride orally disintegrating tablets in the National Medical Insurance Directory [1] Group 1: Company Information - The Amisulpride orally disintegrating tablets are an improved formulation of the Amisulpride tablets launched by Sanofi in France in 1986 [1] - The drug is indicated for the treatment of adult schizophrenia [1] Group 2: Industry Impact - The inclusion of Amisulpride in the National Medical Insurance Directory may enhance its market accessibility and potentially increase sales [1]

Core Viewpoint - Shanghai Pharmaceuticals has officially terminated its cooperation agreement with Guizhou Shengnuo Biotechnology regarding the new acid suppressant project X842, based on a comprehensive assessment of the external market and overall business development plans of all parties involved [1][2]. Group 1: Termination Agreement Details - The termination agreement stipulates that Guizhou Shengnuo must return a total of 110 million yuan (approximately 15.5 million USD) in advance payment and development registration milestone fees to Shanghai Pharmaceuticals within 45 working days after signing the agreement [2]. - Guizhou Shengnuo is also required to pay a fund occupation fee at an annualized interest rate of 3% for the amount returned, calculated based on the actual days of fund occupation [2]. - The dispute resolution mechanism will follow the original agreement, applying Chinese law and submitting disputes to the China International Economic and Trade Arbitration Commission in Beijing [2]. Group 2: Market Context and Implications - The termination of the cooperation is seen as a result of significant changes in the market environment for the X842 project over the four years of collaboration, indicating that the competitive landscape for acid suppressants has become more intense [2]. - The market for proton pump inhibitors (PPIs) already has several established products, and the development progress and market acceptance of the new acid suppressants may not have met expectations [2]. - Shanghai Pharmaceuticals emphasized that the termination will not have a significant impact on its financial status or operational results, and it does not impose any additional unfavorable obligations on its subsidiary, Shanghai Shenyin [3].