Core Viewpoint - The announcement details a change in shareholder equity for WuXi AppTec Co., Ltd., indicating a reduction in the shareholding percentage of the actual controllers and their concerted action parties due to stock dilution and share reduction activities [1][2][3] Group 1: Shareholder Information - The actual controllers of the company are Ge Li, Zhang Chaohui, and Liu Xiaozhong, who control the shareholder entities [1] - The shareholders who signed voting proxies with the actual controllers are also mentioned, indicating a structured governance approach [1] Group 2: Equity Change Details - On October 10, 2025, the company's total share capital increased from 2,965,692,554 shares to 2,983,757,155 shares due to H-share convertible bonds conversion, resulting in a dilution of the shareholding percentage from 18.46% to 18.35% [1] - From November 20 to November 25, 2025, the information disclosure obligor reduced their holdings by 11,827,898 shares, representing 0.40% of the total share capital, decreasing their total shareholding from 547,539,294 shares to 535,711,396 shares, and the percentage from 18.35% to 17.95% [2] Group 3: Compliance and Future Actions - The equity change complies with relevant laws and regulations, does not trigger a mandatory takeover, and will not change the actual control of the company [2][3] - The equity change is attributed to both the increase in total share capital and the execution of a previously disclosed share reduction plan, ensuring adherence to disclosure obligations [3]

（文章来源：证券日报） 证券日报网讯 11月26日晚间，药明康德发布公告称，2025年11月26日，公司收到信息披露义务人发出 的通知，获知其于2025年11月20日至2025年11月25日通过集中竞价方式合计减持公司股份11，827，898 股，占本公告日公司总股本的0.40%。信息披露义务人及与实际控制人签署投票委托书的股东合计持有 公司股份数从547，539，294股减少至535，711，396股，持股比例从18.35%减少至17.95%，权益变动 触及1%刻度。 ...

Group 1 - China Iron & Steel Group disclosed plans for its controlling shareholder to increase its stake in the company by 65 million to 130 million yuan [1][2] - A total of 11 A-share listed companies announced share reductions, including Meixin Technology, Southern Precision, and Huasheng Lithium Electric [1][2] Group 2 - Meixin Technology's shareholders plan to reduce their holdings by no more than 3.57% [2] - Southern Precision's shareholders intend to reduce their holdings by no more than 2.54% [2] - Huasheng Lithium Electric's shareholders plan to reduce their holdings by no more than 0.63% [2] - Other companies such as Bo Technology, Hesheng Co., Jiangbolong, and Zhangjiang Hi-Tech also announced share reductions ranging from 0.50% to 3.06% [2]

智通财经APP获悉，香港联交所最新数据显示，11月21日，摩根大通增持药明康德(02359)73.6509万 股，每股作价102.4881港元，总金额约为7548.34万港元。增持后最新持股数目约为2572.02万股，持股 比例为5.03%。 ...

智通财经APP获悉，香港联交所最新数据显示，11月21日，摩根大通增持药明康德(02359)73.6509万 股，每股作价102.4881港元，总金额约为7548.34万港元。增持后最新持股数目约为2572.02万股，持股 比例为5.03%。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因依賴該等內容而引致之任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B條作出。 茲載列本公司在上海證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 無錫藥明康德新藥開發股份有限公司 董事長 李革博士 香港，2025年11月26日 截至本公告日期，本公司董事會包括執行董事李革博士、陳民章博士、楊青博士及張朝暉先生； 非執行董事童小幪先生及吳亦兵博士；以及獨立非執行董事盧韶華女士、俞衛博士、張新博士、 詹智玲女士及冷雪松先生。 * 僅供識別 证券代码：603259 证券简称：药明康德 公告编号：临 2025-072 关于股东权益变动触及 1%刻度的提示性公告 相关股东保证向公司提供的信息真实、准确、完整，没有虚假记载、误导性陈 ...

Group 1 - JPMorgan's long position in Wuxi AppTec's H-shares increased from 4.89% to 5.03% on November 21, 2025 [1]

证券代码：603259 证券简称：药明康德 公告编号：临 2025-072 关于股东权益变动触及 1%刻度的提示性公告 相关股东保证向公司提供的信息真实、准确、完整，没有虚假记载、误导性陈述或 重大遗漏。 公司董事会及全体董事保证公告内容与相关股东提供的信息一致。 重要内容提示： | 权益变动方向 | 比例增加□ | | 比例减少√ | | --- | --- | --- | --- | | 权益变动前合计比例 | 18.46% | | | | 权益变动后合计比例 | 17.95% | | | | 本次变动是否违反已作出的承 诺、意向、计划 | 是□ | 否√ | | | 是否触发强制要约收购义务 | 是□ | 否√ | | 一、 信息披露义务人及其一致行动人的基本信息 1、身份类别 投资者及其一致行动人的身份 √控股股东/实际控制人及其一致行动人 □其他 5%以上大股东及其一致行动人 □合并口径第一大股东及其一致行动人（仅适用 于无控股股东、实际控制人） □其他______________（请注明） 2、信息披露义务人信息 | 信息披露义务人名称 | | | | | 投资者身份 | | 统一社会信用代码 | ...

Core Viewpoint - The overall market sentiment remains cautiously optimistic, with no significant negative trends observed in the fundamental performance of key sectors, particularly in technology and growth stocks [1] Group 1: Market Performance - As of November 26, 2025, the Shanghai 180 Index rose by 0.30%, with notable increases in stocks such as Haiguang Information (3.95%) and Zhongke Shuguang (3.53%) [1] - The Shanghai 180 ETF Index Fund also saw a slight increase of 0.17%, marking its third consecutive rise [1] Group 2: Sector Analysis - The technology growth sector, including communications and semiconductors, continues to show strong performance, suggesting that recent market adjustments may be positioning for future gains [1] - Despite a slowdown in policy support compared to the first half of the year, the overall market remains in a loose monetary environment, which is expected to support recovery in the technology sector [1] Group 3: Investment Strategy - A "barbell strategy" is recommended for investment, suggesting to maintain positions in growth sectors like communications, semiconductors, and innovative pharmaceuticals while being cautious with short-term operations [1] - Defensive investments in dividend-paying sectors are advised to mitigate risks during market fluctuations [1] Group 4: Index Composition - The Shanghai 180 Index comprises 180 large-cap stocks selected for their market capitalization and liquidity, reflecting the overall performance of core listed companies in the Shanghai securities market [2] - As of October 31, 2025, the top ten weighted stocks in the index account for 26.29% of the total index, with notable companies including Kweichow Moutai and China Ping An [2]

Market Overview - The Hong Kong stock market showed a significant recovery on November 24, with all three major indices ending a streak of declines[9] - Large tech stocks performed strongly, with Kuaishou rising over 7%, and NetEase and Bilibili increasing over 5%[9] - The Hang Seng Tech Index closed at 5,546, up 2.78% for the day and 24.11% year-to-date[3] Sector Performance - Innovative pharmaceuticals and outsourcing concepts saw notable gains, with companies like Innovent Biologics rising over 6%[9] - Military stocks also performed well, with China Shipbuilding Defense up over 13%[9] - Oil stocks were weak, with China National Offshore Oil Corporation and China Oilfield Services both declining over 1%[9] U.S. Market Insights - On the same day, U.S. markets saw all three major indices close higher, driven by increased bets on a Federal Reserve rate cut[9] - The "Magnificent Seven" tech stocks, including Google and Nvidia, all rose, with Google gaining over 6%[9] - The S&P 500 index is projected to achieve double-digit annual growth according to HSBC strategists[14] Economic Indicators - The Federal Reserve is expected to cut rates in December, with market predictions showing a 70% probability[14] - The U.S. economy's third-quarter GDP report has been delayed due to a government shutdown, affecting economic analysis[14] Investment Trends - The Nasdaq Golden Dragon China Index rose by 2.82%, indicating a positive trend for Chinese concept stocks[13] - Significant inflows into semiconductor stocks were noted, with companies like Broadcom surging 11%[13]