Investment Rating - The report maintains a "Buy" rating for WuXi AppTec, indicating a potential return of over 15% in the next 12 months [19]. Core Insights - WuXi AppTec reported strong financial performance for Q1 2025, with revenue increasing by 21.0% year-on-year to RMB 9.65 billion, and adjusted non-IFRS net profit rising by 40.0% to RMB 2.68 billion [1][2]. - The TIDES business segment experienced significant growth, with revenue soaring by 187.6% to RMB 22.4 billion, driven by expanded capacity and contributions from oral GLP-1 projects [2]. - Despite ongoing macroeconomic uncertainties, management reaffirmed its annual performance guidance, expecting a revenue growth of 10-15% and an expansion in adjusted non-IFRS net profit margin [1][2]. Financial Summary - For FY25E, revenue is projected at RMB 42.97 billion, reflecting a year-on-year growth of 9.5%, while adjusted net profit is expected to reach RMB 11.61 billion, a growth of 9.7% [4][16]. - The company’s unfulfilled contract amount grew by 47.1% year-on-year to RMB 52.33 billion by the end of Q1 2025, indicating a solid foundation for future growth [1]. - The report also highlights a decrease in the P/E ratio from 16.5 in FY24A to 15.0 in FY25E, suggesting improved valuation attractiveness [4][16]. Shareholder Returns - WuXi AppTec's board proposed a series of shareholder return plans, including maintaining a 30% annual cash dividend payout ratio and a one-time special dividend of RMB 10 billion in 2025 [3]. - The total proposed dividend and buyback plan amounts to nearly RMB 60 billion, representing 62% of the net profit attributable to shareholders for 2024 [3]. Valuation - The target price has been adjusted from RMB 94.05 to RMB 77.22 based on DCF valuation, reflecting a downside risk of 27.7% from the current price of RMB 60.45 [5][6].

Group 1 - Goldman Sachs raised the target price for WuXi AppTec to HKD 74.9, up from HKD 70.9, maintaining a "Neutral" rating [1] - The company reported strong Q1 performance, and management has maintained its guidance for FY 2025, aligning with Goldman Sachs' expectations [1] - If the company continues its strong performance in the next 1-2 quarters, there is potential for an upward revision of guidance in the second half of the year [1] Group 2 - Goldman Sachs expects the TIDES business to grow by 65% this year, surpassing the official guidance of 60% [1] - The revenue forecasts for the TIDES business for 2025 to 2027 have been increased by 3.1%, 5%, and 5% respectively [1] - The profit forecasts for 2025 to 2027 have been raised by 7%, 3.5%, and 2.3% respectively, reflecting better-than-expected performance in TIDES and small molecule R&D and manufacturing [1]

Core Viewpoint - WuXi AppTec (药明康德) has reported significant growth in its Q1 2025 financial results, with revenue and net profit reaching historical highs, driven by increased production capacity and operational efficiency [2][4]. Financial Performance - In Q1 2025, WuXi AppTec achieved revenue of 96.55 billion yuan, a year-on-year increase of 20.96%, and net profit of 36.72 billion yuan, up 89.06% [2][4]. - The company’s ongoing business orders reached 523.3 billion yuan as of March 31, 2025, reflecting a 47.1% year-on-year growth [3][10]. Business Segments - The TIDES (oligonucleotide and peptide) business generated revenue of 22.4 billion yuan in Q1 2025, marking a substantial year-on-year increase of 187.6% [3][10]. - The chemical business reported revenue of 73.91 billion yuan, up 32.87% year-on-year, with over 460,000 new compounds synthesized and delivered in the past 12 months [9]. - The small molecule D&M (Development and Manufacturing) business achieved revenue of 38.5 billion yuan, a 13.8% increase year-on-year [9]. Operational Efficiency - WuXi AppTec has optimized production processes and operational efficiency, contributing to improved profitability [4][10]. - The company has successfully passed FDA inspections for its Changzhou and Taixing API bases, with plans to increase small molecule API reactor capacity to over 4,000 KL by the end of 2025 [9]. Future Outlook - WuXi AppTec maintains its annual guidance, expecting a revenue growth of 10% to 15% for its ongoing business in 2025 [11].

证券代码：603259 证券简称：药明康德 公告编号：临 2025-032 无锡药明康德新药开发股份有限公司 2024年年度股东大会、2025 年第一次 A 股类别股东会 议及 2025 年第一次 H 股类别股东会议决议公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 本次会议是否有否决议案：无 一、 会议召开和出席情况 | 年年度股东大会 2024 | | | --- | --- | | 1、出席会议的股东和代理人人数 | 3,794 | | 其中：A 股股东人数 | 3,793 | | 股） 境外上市外资股股东人数（H | 1 | | 2、出席会议的股东所持有表决权的股份总数（股） | 1,202,669,172 | | 其中：A 股股东持有股份总数 | 1,014,650,572 | | 境外上市外资股股东持有股份总数（H 股） | 188,018,600 | | 3、出席会议的股东所持有表决权股份数占公司有表决权股 | | | 份总数的比例（%） | 41.6702 | | 其中：A | 股股东持股 ...

同日，公司 2024 年年度股东大会审议通过《关于 2025 年以集中竞价交易方 式回购公司 A 股股份的议案》，同意公司采用集中竞价交易方式回购公司 A 股股 份，回购的股份将在回购完成之后全部予以注销并减少注册资本。本次拟回购 A 股股份的资金总额为人民币 10 亿元，若按回购价格上限人民币 92.05 元/股测算， 预计本次回购股份数量约为 10,863,661 股，约占公司于本公告日已发行总股本 （即 2,887,992,582 股）的 0.38%（具体回购股份的数量和占公司总股本的比例以 回购完毕或回购期限届满时实际回购的股份数量为准）。具体内容详见 2024 年年 度股东大会相关公告。 根据上述回购方案，以公司本公告日的总股本为基础且仅考虑回购注销前述 预 计 本 次 回 购 股 份 数 量 约 为 10,863,661 股 计 算 ， 本 公 司 的 注 册 资 本 由 1 2,887,992,582 元减少为 2,877,128, 921 元，本公司的股份总数由 2,887,992,582 股 减少为 2,877,128,921 股。最终公司总股本及注册资本的变动情况以回购实际情 况及对应的减 ...

FANGDA PARTNERS http://www.fangdalaw.com 中国北京市朝阳区光华路一号 电子邮件 E-mail: email@fangdalaw.com 北京嘉里中心北楼 27 层 电 话 Tel.: 86-10-5769-5600 邮政编码：100020 传 真 Fax: 86-10-5769-5788 27/F，North Tower, Beijing Kerry Centre 1 Guanghua Road, Chaoyang District Beijing 100020, PRC 上海市方达（北京）律师事务所 关于无锡药明康德新药开发股份有限公司 2024 年年度股东大会、2025 年第一次 A 股类别股东会议及 2025 年第一次 H 股类别股东会议的法律意见书 致：无锡药明康德新药开发股份有限公司 上海市方达（北京）律师事务所（以下简称"本所"）是具有中华人民共和国 境内法律执业资格的律师事务所。根据相关法律顾问协议，本所指派律师出席无 锡药明康德新药开发股份有限公司（以下简称"药明康德"或"公司"）2024 年年度 股东大会、2025 年第一次 A 股类别股东会议及 20 ...

无锡药明康德新药开发股份有限公司 章 程 (2025年修订) | 第一章 | 总则 1 | | --- | --- | | 第二章 | 经营宗旨和范围 2 | | 第三章 | 股份 3 | | 第一节 | 股份发行 3 | | 第二节 | 股份增减和回购 5 | | 第三节 | 股份转让 7 | | 第四节 | 购买公司股份的财务资助 9 | | 第五节 | 股票和股东名册 9 | | 第四章 | 股东和股东大会 11 | | 第一节 | 股东 11 | | 第二节 | 股东大会的一般规定 13 | | 第三节 | 股东大会的召集 17 | | 第四节 | 股东大会的提案与通知 19 | | 第五节 | 股东大会的召开 20 | | 第六节 | 股东大会的表决和决议 23 | | 第七节 | 类别股东表决的特别程序 27 | | 第五章 | 董事会 29 | | 第一节 | 董事 29 | | 第二节 | 独立董事 32 | | 第三节 | 董事会 34 | | 第六章 | 经理（总裁、首席执行官）及其他高级管理人员 40 | | 第七章 | 监事会 43 | | 第一节 | 监事 43 | | 第二节 | ...

FF305 翌日披露報表 (股份發行人 ── 已發行股份或庫存股份變動、股份購回及/或在場内出售庫存股份) 表格類別： 股票 狀態： 新提交 | 1). | 購回股份(或其他證券)但沒有註銷 | 379,300 | 0.02 % | RMB | 52.75 | | --- | --- | --- | --- | --- | --- | | | 茲提述本公司於2025年4月8日刊發的公告。 | | | | | | | 於2025年4月18日，本公司實施2025年第二次股份回購，并回購 | | | | | | | 379,300股A股股份。 | | | | | | | 變動日期 2025年4月18日 | | | | | | 2). | 購回股份(或其他證券)但沒有註銷 | | | | | | | | 374,000 | 0.01 % | RMB | 53.5 | | | 茲提述本公司於2025年4月8日刊發的公告。 | | | | | | | 於2025年4月21日，本公司實施2025年第二次股份回購，并回購 | | | | | | | 374,000股A股股份。 | | | | | | | 變動日期 2025年 ...

Investment Rating - The report maintains a "Buy" rating for WuXi AppTec (603259) [2] Core Insights - WuXi AppTec reported a significant revenue increase of 21.0% year-on-year, reaching 9.65 billion yuan in Q1 2025, with a notable 89.1% growth in net profit attributed to one-time investment gains [5][8] - The company has a strong order backlog of 52.33 billion yuan, reflecting a 47.1% year-on-year increase, with TIDES orders growing by 105.5% [8] - The company plans to distribute a special dividend of 1 billion yuan in addition to maintaining a 30% annual cash dividend ratio, alongside a share buyback of 1 billion yuan [8] Financial Data and Profit Forecast - Total revenue projections for 2025 are estimated at 42.77 billion yuan, with a year-on-year growth rate of 9.0% [7] - The forecasted net profit for 2025 is 11.27 billion yuan, representing a 19.3% increase compared to the previous year [7] - The report anticipates a continued double-digit growth trajectory for the company's core business, with overall revenue expected to reach between 41.5 billion and 43 billion yuan [8]

Investment Rating - The investment rating for WuXi AppTec (603259) is "Buy" [5] Core Views - The company's Q1 2025 performance exceeded market expectations, with a revenue of 9.655 billion yuan, a year-on-year increase of 20.96%, and a net profit attributable to shareholders of 3.672 billion yuan, up 89.06% year-on-year [1][2] - The TIDES business significantly contributed to the core performance elasticity, with a revenue of 2.24 billion yuan, representing a remarkable growth of 187.6% year-on-year [2] - The company has a strong order backlog of 52.33 billion yuan, a year-on-year increase of 47.1%, indicating a continued high growth trend [2] Summary by Sections Financial Performance - For Q1 2025, the company achieved a revenue of 9.655 billion yuan, a 21.0% increase year-on-year, with adjusted profit reaching 2.68 billion yuan, up 40% [2] - The chemical business generated 7.39 billion yuan in revenue, a 32.9% increase year-on-year, while the small molecule CDMO business saw a revenue of 3.85 billion yuan, growing 13.8% [2] - The testing and biology segments reported revenues of 1.29 billion yuan and 610 million yuan, showing a decline of 4% and an increase of 8.2% respectively [2] Future Outlook - The company expects a revenue growth guidance of 10% to 15% for its continuing operations in 2025, supported by rapid order growth and ongoing cost reduction efforts [2] - The adjusted revenue forecasts for 2025-2027 are 42.724 billion yuan, 49.093 billion yuan, and 56.747 billion yuan respectively, with EPS estimates of 4.17 yuan, 4.94 yuan, and 5.85 yuan [3][8] Valuation Metrics - The PE ratios for 2025, 2026, and 2027 are projected to be 15, 12, and 10 respectively, based on the closing price of 60.45 yuan per share on April 29, 2025 [3]