股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年7月31日 狀態: 新提交 FF301 致：香港交易及結算所有限公司 公司名稱: 上海君實生物醫藥科技股份有限公司 呈交日期: 2025年8月6日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 01877 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 260,295,700 | RMB | | 1 RMB | | 260,295,700 | | 2. 股份分類 | 普通股 | 股份類別 ...

Core Viewpoint - Junshi Biosciences is positioned as a leading innovative pharmaceutical company in China, focusing on the development and commercialization of first-in-class and best-in-class drugs, with a comprehensive industry chain from drug discovery to large-scale production and global clinical research [2][3]. Company Overview - Junshi Biosciences was established on December 27, 2012, and went public on July 15, 2020. The company is headquartered in Shanghai and specializes in the research and commercialization of monoclonal antibody drugs and other therapeutic protein drugs [7]. - The main revenue sources for the company include drug sales (84.18%), technology licensing and royalties (12.08%), and other income (3.73%) [7]. Recent Developments - On October 27, 2023, Junshi Biosciences announced a collaboration with Peking University, the Institute of Microbiology of the Chinese Academy of Sciences, Shanxi Advanced Innovation Research Institute, and Beihang University to jointly develop a monkeypox recombinant protein vaccine [3]. - The company’s subsidiary, JunTuo Biotech, is involved in the development of vaccine-related products, including monkeypox and Zika vaccines, which are currently in the preclinical development stage [3]. Financial Performance - For the period from January to March 2025, Junshi Biosciences reported a revenue of 5.01 billion yuan, representing a year-on-year growth of 31.46%. However, the net profit attributable to the parent company was -2.35 billion yuan, showing a year-on-year increase of 17.01% [8]. Market Activity - On August 6, 2023, Junshi Biosciences' stock rose by 4.61%, with a trading volume of 1.663 billion yuan and a turnover rate of 5.09%, bringing the total market capitalization to 42.382 billion yuan [1].

Group 1 - The Shanghai Stock Exchange Sci-Tech Innovation Board Biopharmaceutical Index increased by 0.85%, with notable stock performances including Boryung Pharmaceutical up by 15.37% and Junshi Biosciences up by 6.49% [1] - The market activity for the Jiashi Sci-Tech Medicine ETF was robust, with a turnover rate of 18.13% and a transaction volume of 42.47 million yuan, leading in comparable funds [3] - As of August 5, the Jiashi Sci-Tech Medicine ETF achieved a net inflow of 11.73 million yuan, totaling 14.69 million yuan over the last five trading days [3] Group 2 - The top ten weighted stocks in the Sci-Tech Innovation Board Biopharmaceutical Index accounted for 49.14% of the index, with leading stocks including United Imaging Healthcare and Boryung Pharmaceutical [3][5] - A significant business development deal was announced by Crystal Technology Holdings, with a total order size of approximately 47 billion HKD (5.99 billion USD), marking it as one of the largest BD transactions in China's AI pharmaceutical sector for 2025 [5] - According to research from Everbright Securities, the mid-year reporting period in July may lead to positive changes in the performance of some innovative drug companies, potentially catalyzing a new market trend [6]

本文源自：金融界AI电报 昨日暴涨近34%的君实生物(1877.HK)今日回调，盘中跌12%报28.32港元。 ...

北京商报讯（记者 丁宁）8月6日，创新药概念股再度走强，其中，君实生物（688180）涨超10%，泓 博医药、康弘药业、悦康药业等个股跟涨。 ...

Group 1 - The core viewpoint of the news highlights the positive performance of the biotech sector, particularly driven by a significant collaboration in the AI pharmaceutical space, which has boosted investor sentiment and stock prices of key companies in the sector [1][2] - The Kexin Biopharmaceutical ETF (588250.SH) rose by 0.89%, with its associated index Kexin Biopharmaceutical (000683.SH) increasing by 0.90%. Notable stock performances included Junshi Biosciences-U up by 10.92% and CanSino up by 7.96% [1] - A major order of approximately $59.9 billion was announced by Crystal Technology Holdings, which is expected to enhance the innovation drug sector's outlook and positively impact related stocks [1] Group 2 - Research from Guolian Minsheng Securities indicates a strong net subscription performance for pharmaceutical and biotech theme funds in Q2 2025, with notable funds like Huatai Fuyou Innovation Medicine A and Yongying Medicine Innovation Smart Selection C leading in net subscriptions [2] - The innovative drug industry is reportedly at a turning point, with domestic pharmaceutical companies achieving commercial closure through business development collaborations, which is expected to improve the financing environment and support valuation recovery for innovative drug companies [2]

上海君实生物医药科技股份有限公司主要业务是发现、开发和商业化创新疗法，特别是在肿瘤免疫疗 法、自身免疫系统疾病、慢性代谢类疾病、神经系统疾病、感染类疾病等治疗方面。公司拥有卓越的创 新药物发现能力、先进的生物技术研发、全产业链大规模生产技术和极具市场潜力的在研药品组合。 8月6日，君实生物(01877)盘中下跌4.91%，截至09:45，报30.6元/股，成交3.36亿元。 本文源自：金融界 作者：行情君 截至2025年一季报，君实生物营业总收入5.01亿元、净利润-2.35亿元。 ...

君实生物(01877.HK)回调，开跌超8%，昨日收涨近34%。 ...

专题：专题|2024年度A股CFO数据报告：美的集团钟铮年薪946万，比亚迪周亚琳896万 许宝红先生自2020年11月起担任君实生物财务总监。其专业背景深厚，2004年毕业于上海财经大学，先 后获得经济学学士和管理学硕士学位。职业履历主要集中于财务、投资与研究领域，目前担任君实生物 医药科技（海南）有限公司及君实创业投资（海南）有限公司执行董事兼总经理职务。 （图：新浪财经统计2024年医药生物行业的上海地区上市公司CFO薪酬前十） 在上海地区这一经济与行业高地，样本平均年薪显示，上海地区医药生物行业CFO薪酬水平为113.91万 元（样本为39家上市公司）。这一数字较A股全市场CFO平均值高出32.43万元，溢价幅度达39.8%，凸 显上海作为经济中心的高运营成本与医药生物高附加值行业属性叠加带来的薪酬竞争力。 君实生物-U（688180.SH）财务总监许宝红以2024年度薪酬206.02万元，其2024年薪酬虽同比下降 24.66%，但仍位列上海医药生物行业CFO薪酬榜第五名。 聚焦医药生物行业（申万一级），纳入统计的395家上市公司CFO平均年薪约为91.97万元，显著高于全 市场均值。 | | | ...

Core Viewpoint - Junshi Biosciences-U's stock price has shown an upward trend, reflecting positive market sentiment towards its innovative drug development and commercialization efforts [1] Company Overview - Junshi Biosciences-U's latest stock price is 39.46 yuan, up by 1.80 yuan from the previous trading day, with a trading volume of 196,000 hands and a transaction amount of 755 million yuan [1] - The company specializes in the research and commercialization of innovative drugs, with its core product being the first domestically approved PD-1 monoclonal antibody, Toripalimab injection, which has received approval for 12 indications, 10 of which are included in the national medical insurance catalog [1] - The company has established a diverse research and development system covering monoclonal antibodies, bispecific antibodies, and ADCs, with R&D centers located in the US, Shanghai, and Suzhou [1] Financial Activities - Recently, the company raised over 1 billion Hong Kong dollars through a rights issue, with 70% of the funds allocated for innovative drug research and development, including PD-1/VEGF bispecific antibodies and EGFR/HER3 bispecific ADCs [1] - In the first quarter of 2025, the total number of license-out transactions for innovative drugs in China reached 41, with a total value of 36.929 billion US dollars [1] Market Position - Junshi Biosciences-U has established a global commercialization network covering over 80 countries and regions, utilizing various models such as licensing and joint ventures to advance its international strategy [1] - As of August 5, 2025, the net inflow of main funds into Junshi Biosciences-U was 45.8254 million yuan, accounting for 0.15% of its circulating market value, while the cumulative net outflow over the past five trading days was 126 million yuan, representing 0.42% of its circulating market value [1]