| | | 首药控股（北京）股份有限公司 章程 首药控股（北京）股份有限公司 章程 二〇二五年八月 第三条 公司于 2022 年 1 月 28 日经中国证券监督管理委员会（以下称"中国 证监会"）同意注册，首次向社会公众发行人民币普通股 3,718.00 万股并于 2022 年 3 月 23 日在上海证券交易所科创板上市。 第四条 公司注册名称： 中文全称：首药控股（北京）股份有限公司 英文全称：Shouyao Holdings (Beijing) Co., Ltd. 公司性质：股份有限公司 第五条 公司住所：北京市北京经济技术开发区荣华中路 10 号 1 幢 19 层 1 单元 2202-2 号，邮政编码：100176。 第一章 总则 第一条 为维护首药控股（北京）股份有限公司（以下称"公司"）、股东、职 工和债权人的合法权益，规范公司的组织和行为，根据《中华人民共和国公司法》 （以下称"《公司法》"）《中华人民共和国证券法》（以下称"《证券法》"）《上 市公司章程指引》《上海证券交易所科创板股票上市规则》等法律、行政法规、 部门规章和其他有关规定，制定本章程。 第六条 公司注册资本为人民币 14,871. ...

首药控股（北京）股份有限公司 董事、高级管理人员离职管理制度 首药控股（北京）股份有限公司 董事、高级管理人员离职管理制度 第一章 总则 第一条 为完善首药控股（北京）股份有限公司（以下称"公司"）董事离职 程序，确保公司治理结构的稳定性和连续性，维护公司及股东的合法权益，公司 根据《中华人民共和国公司法》（以下称"《公司法》"）、《中华人民共和国证 券法》（以下称"《证券法》"）、《上市公司章程指引》《上海证券交易所科创 板股票上市规则》《上海证券交易所科创板上市公司自律监管指引第 1 号——规 范运作》（以下称"《1 号自律监管指引》"）等法律法规、规范性文件、上海证 券交易所业务规则及《首药控股（北京）股份有限公司章程》（以下称"《公司 章程》"）的有关规定，结合公司实际情况，制定本制度。 第二条 本制度适用于公司董事（含独立董事）及高级管理人员因任期届满、 辞职、被解除职务或其他原因离职的情形。 第三条 公司董事、高级管理人员离职管理应遵循以下原则： （一）合法合规原则：严格遵守国家法律法规、监管规定及《公司章程》的 要求； （二）公开透明原则：及时、准确、完整地披露董事、高级管理人员离职相 关信息； ...

首药控股公告，2025年上半年营业收入200万元，同比下降47.37%。归属于上市公司股东的净利润-1.04 亿元，上年同期为-1.03亿元。研发投入占营业收入的比例5,408.49%，增加2590.03个百分点。 ...

Group 1 - The stock of Shouyao Holdings (688197) closed at 55.94 yuan on August 13, reaching the daily limit with a trading volume of 3.58 billion yuan and a turnover rate of 10.63% [2] - The stock was listed on the daily trading list due to a price increase of 15% at the close [2] - The top five trading departments accounted for a total transaction of 1.41 billion yuan, with a net buying amount of 38.7 million yuan [2][3] Group 2 - The main capital inflow for the stock was 45.79 million yuan throughout the day [3] - The largest buying department was the Shanghai-Hong Kong Stock Connect, with a buying amount of 31.85 million yuan [3] - The largest selling department was the Industrial Securities Co., Ltd., with a selling amount of 20.42 million yuan [3]

作者：智投君 兴业证券股份有限公司上海古北路证券营业部、开源证券股份有限公司北京分公司、沪股通专用分别卖 出2041.59万元、839.05万元、808.68万元。 买入金额最大的前5名营业部 买入额/万 卖出额/万 净额/万 沪股通专用 3185.05 0.00 3185.05 中信证券股 份有限公司杭州凤起路证券营业部 2199.56 0.00 2199.56 开源证券股份有限公司西安西大街证券营业部 1684.07 0.00 1684.07 华鑫证券有限责任公司上海宛平南路证券营业部 974.48 0.00 974.48 机构专用 954.31 0.00 954.31 卖出金额最大的前5名营业部 买入额/万 卖出额/万 净额/万 兴业证券股份有限公司上 海古北路证券营业部 0.00 2041.59 -2041.59 开源证券股份有限公司北京分公司 0.00 839.05 -839.05 沪股 通专用 0.00 808.68 -808.68 机构专用 0.00 727.22 -727.22 机构专用 0.00 711.30 -711.3 本文源自：金融界 8月13日，首药控股上涨19.99%登上龙虎榜，有 ...

资金流向方面，首药控股-U当日主力资金净流入4646.49万元，近五日累计净流入7053.19万元。 截至2025年8月13日收盘，首药控股-U股价报55.94元，较前一交易日上涨19.99%。当日开盘价为46.60 元，最高触及55.94元，最低下探46.07元，成交量为68039手，成交额达3.58亿元。 首药控股-U属于生物医药行业，专注于创新药的研发与商业化。公司主要产品管线涵盖肿瘤、自身免 疫疾病等领域，致力于为临床需求提供差异化治疗方案。 消息面上，国家医保局近期推出"新上市药品首发价格机制"，旨在鼓励药品研发创新，为高质量创新药 提供更灵活的定价空间。此外，2025年医保目录调整初步形式审查结果显示，多款创新药进入审查名 单，市场对创新药行业关注度提升。 风险提示：市场波动风险，行业政策变化风险，研发进展不及预期风险。 来源:金融界 ...

Group 1 - The chemical pharmaceutical sector increased by 2.34% on August 13, with Shouyao Holdings leading the gains [1] - The Shanghai Composite Index closed at 3683.46, up 0.48%, while the Shenzhen Component Index closed at 11551.36, up 1.76% [1] - Notable gainers in the chemical pharmaceutical sector included Shouyao Holdings, which rose by 19.99% to a closing price of 55.94, and Weichip Bio, which increased by 14.39% to 41.18 [1] Group 2 - The chemical pharmaceutical sector saw a net inflow of 342 million yuan from main funds, while retail investors contributed a net inflow of 426 million yuan [2] - Major stocks with significant net inflows included Heng Rui Pharmaceutical with 55.1 million yuan and Fu Xing Pharmaceutical with 23.4 million yuan [3] - Conversely, stocks like ST Sailong and ST Suwu experienced notable net outflows of 4.97% and 3.70%, respectively [2]

Market Overview - A-shares experienced a significant rally, with the Shanghai Composite Index achieving an 8-day winning streak and reaching a new high since December 2021, closing at 3683.46 points, up 0.48% [1] - The total trading volume in the A-share market exceeded 2 trillion yuan for the first time since February 27, with a total of 21,756 billion yuan traded [1] - The Hong Kong stock market also saw substantial gains, with the Hang Seng Index rising over 2% and the Hang Seng Tech Index increasing over 3% [1] AI Industry - AI-related stocks surged, with notable gains including Guangku Technology and Robotech both hitting the 20% limit up, and Industrial Fulian also reaching the limit up [2][4] - Industrial Fulian reported a revenue of 360.76 billion yuan for the first half of 2025, a year-on-year increase of 35.58%, and a net profit of 12.11 billion yuan, up 38.61% [4][5] - The demand for AI servers is expected to grow significantly, driven by increased capital expenditures from major North American cloud service providers [4][5] Innovative Pharmaceuticals - The innovative drug sector saw strong performance, with Shouyao Holdings hitting the 20% limit up, and other companies like Microchip Biotech and WuXi AppTec also posting significant gains [6][8] - The National Medical Insurance Administration has established a "new drug pricing mechanism," which is expected to provide innovative drug manufacturers with greater pricing flexibility and efficiency [8] Humanoid Robotics - The humanoid robotics sector showed renewed activity, with companies like Shenglan Co. and Jieke Co. seeing substantial increases in stock prices [9][11] - The World Robot Conference held in Beijing highlighted advancements in embodied intelligent robots, with local governments offering subsidies for robot purchases [9][11] - The industry is expected to benefit from various supportive policies and events, including the upcoming World Humanoid Robot Games and other robotics-related conferences [11]

创新药概念股，再度异动！ 在高位盘整多日之后，创新药概念股今日再度走强。临近午盘时分，首药控股直线拉升至20cm涨停，海思科盘中也触及涨停，药明康德、美迪西、常山 药业、凯莱英等纷纷走强。 从消息面来看，国家医保局12日对2025年国家医保药品目录初步形式审查结果进行公示，534个药品通过形式审查，较2024年明显增加。首次设立的商保 创新药目录共121个药品通过审查。有券商指出，在医保基础上补充发展商保，有利于具有创新性和临床价值的高价创新药落地。 创新药概念股拉升 8月13日，A股三大指数震荡攀升，创业板指大涨近3%。液冷服务器、CPO、PEEK材料、券商等板块纷纷走强。临近午盘时，创新药概念股也集体发力， 首药控股率先20cm涨停。紧随其后，海思科也被资金拉升至涨停板，股价创出历史新高。美迪西、上海谊众、仙琚制药、昭衍新药、常山药业、凯莱英 等纷纷跟涨。午后，行业巨头药明康德的股价涨幅一度超过8%，市值逼近2900亿元。 从消息面来看，创新药板块近期的利好消息相当密集。8月12日，国家医保局对2025年国家医保药品目录初步形式审查结果进行公示，534个药品通过形式 审查。 值得关注的是，2025年目录调 ...

Core Viewpoint - The innovative drug concept stocks have shown strong performance recently, driven by favorable policy developments and market dynamics [1][4][5]. Group 1: Market Performance - Innovative drug stocks surged, with Shouyao Holdings hitting a 20% limit up and Haishike also reaching the limit, alongside significant gains from companies like WuXi AppTec and MediSino [1][5]. - Since the start of the current market rally on April 8, the innovative drug sector has seen an overall increase of nearly 60%, with individual stocks like Shutai Shen rising nearly 7 times and Guangsheng Tang over 4 times [5][6]. Group 2: Policy Developments - The National Medical Insurance Administration (NMI) announced that 534 drugs passed the preliminary review for the 2025 National Medical Insurance Drug List, a significant increase from 2024 [4][6]. - A new commercial insurance innovative drug list was established, with 121 drugs approved, indicating a shift towards integrating commercial health insurance with basic medical insurance [6][7]. - The NMI's recent meetings emphasized support for genuine innovation in the pharmaceutical sector, aiming to enhance the quality of drugs and medical devices while rejecting subpar innovations [7][8]. Group 3: Industry Outlook - Analysts are optimistic about the investment opportunities within the pharmaceutical industry, driven by supportive policies and the potential for market recovery in the second half of 2025 [8][9]. - The total market size for innovative drugs in China is estimated to be between 200 billion and 300 billion, with significant growth potential as the country becomes a global R&D hub for innovative drugs [9]. - The policy environment remains favorable for innovative drugs, with major pharmaceutical companies gradually clearing risks associated with drug procurement, paving the way for competitive innovative drug pipelines [9].