Core Insights - The stock price of United Imaging Healthcare (688271) closed at 147.9 yuan on September 19, 2025, down 1.4% from the previous trading day, with a total market capitalization of 121.893 billion yuan [1] - The company reported a revenue of 6.016 billion yuan for the first half of 2025, representing a year-on-year growth of 12.79% [1] - The net profit attributable to shareholders was 999.8 million yuan, up 5.03% year-on-year, while the net profit excluding non-recurring items was 966 million yuan, showing a growth of 21.01% [1] - Overseas revenue reached 1.142 billion yuan, marking a year-on-year increase of 22.48% [1] - Research and development (R&D) expenses totaled 1.14 billion yuan, with capitalized R&D investments increasing by 95.56% year-on-year [1] - The company has maintained compliance in the use of raised funds, and there have been no significant issues or violations reported during the review period [1]

Core Viewpoint - The Chinese innovative drug industry is gradually catching up with Europe and the United States in terms of technology, with some targets and technical pathways already leading globally. The number and value of new drugs authorized for overseas markets continue to increase, leading to world-class pricing and non-linear investment elasticity. The domestic market is experiencing strong growth in demand, with domestic new drug sales continuing to rise, and several innovative pharmaceutical companies have turned losses into profits, entering a stable growth phase [2]. Group 1: Innovative Drugs - The innovative drug sector is witnessing a significant increase in sales driven by strong domestic demand, with a number of innovative companies achieving profitability [2]. - The trend of domestic innovative drugs going overseas is accelerating, with increasing numbers and values of new drug authorizations [2]. - The pricing power of innovative drugs is improving, reflecting the global competitiveness of Chinese pharmaceutical companies [2]. Group 2: High-Value Medical Consumables - The orthopedic sector is expected to see mild price reductions due to continued domestic substitution and accelerated overseas business progress [2]. - The neurosurgery and neurointervention fields are experiencing stable growth post-collection, with new products being launched [2]. - The high-value consumables market is expected to benefit from ongoing domestic replacement and the introduction of new products [2]. Group 3: Medical Devices - The medical device sector is seeing a recovery in bidding prices, with ongoing high-speed growth in bidding data this year [2]. - Companies are entering a phase of inventory reduction, with performance expected to improve in the second half of the year [2]. - The low-value consumables sector is experiencing product upgrades and accelerated expansion into overseas markets [2]. Group 4: Blood Products - The supply side of the blood products industry is concentrating on central state-owned enterprises, gradually clearing the competitive landscape [2]. - The demand side is expected to see continuous upgrades to new products, with industry sentiment gradually improving [2]. Group 5: API (Active Pharmaceutical Ingredients) - The API sector is benefiting from the end of a capital expenditure peak, with three growth logic points driving upward trends: new high-end market products, integrated consolidation and overseas expansion, and cost-leading CDMO [2]. - Leading companies in the API sector are expected to see explosive growth in revenue and profits [2]. Group 6: CXO (Contract Research Organization) - The CXO sector is witnessing a recovery in A+H financing activity, with multiple significant business developments enhancing market confidence [2]. - The focus is on optimizing the supply-side landscape and increasing market share for leading CRO companies [2]. Group 7: Traditional Chinese Medicine and Retail Pharmacy - The traditional Chinese medicine sector is showing signs of recovery, with friendly pricing for new drugs and ongoing observation of collection progress [2]. - The retail pharmacy sector is influenced by the pace of supply-side clearing and business model upgrades, with expectations of increased store closures in the second half of 2025 [2]. Group 8: Research and Development Services - The domestic innovative drug business development is heating up, likely driving downstream demand recovery [2]. - The overseas market presents significant growth opportunities for domestic companies, leveraging cost-effectiveness and service differentiation [2].

Market Performance - The Medical Health Index (980016) closed at 7021.34 points, down 1.08%, with a trading volume of 33.906 billion yuan and a turnover rate of 1.07% [1] - Among the index constituents, 5 stocks rose while 45 stocks fell, with Yirui Technology leading the gainers at 1.82% and Changchun High-tech leading the decliners at 3.91% [1] Key Constituents - The top ten constituents of the Medical Health Index include: - WuXi AppTec (13.58% weight) at 108.75 yuan, up 1.23% with a market cap of 320.976 billion yuan - Hengrui Medicine (10.87% weight) at 69.65 yuan, down 2.03% with a market cap of 462.281 billion yuan - Mindray Medical (8.17% weight) at 235.00 yuan, down 1.18% with a market cap of 284.924 billion yuan - United Imaging Healthcare (4.14% weight) at 147.90 yuan, down 1.40% with a market cap of 121.893 billion yuan - Other notable constituents include Pianzai Shou, Yier Eye Hospital, Kelun Pharmaceutical, Xinhecheng, Fosun Pharma, and Yixiao Aoshi [1] Capital Flow - The Medical Health Index constituents experienced a net outflow of 2.29 billion yuan from institutional investors, while retail investors saw a net inflow of 2.013 billion yuan [3] - Notable capital flows include: - Mindray Medical with a net inflow of 98.789 million yuan from institutional investors and a net outflow of 10.5 million yuan from speculative funds - Changchun High-tech with a net inflow of 67.986 million yuan from institutional investors and a significant net outflow from speculative funds [3]

中信证券股份有限公司、中国国际金融股份有限公司 一、持续督导工作概述 关于上海联影医疗科技股份有限公司 2025 年半年度持续督导跟踪报告 中信证券股份有限公司（以下简称"中信证券"或"保荐人"）和中国国际金融 股份有限公司（以下简称"中金公司"或"保荐人"）作为上海联影医疗科技股 份有限公司（以下简称"联影医疗"或"公司"）首次公开发行股票并在科创板 上市项目的保荐人，根据《证券发行上市保荐业务管理办法》《上海证券交易所 科创板股票上市规则》等相关规定，中信证券和中金公司履行持续督导职责，并 出具本持续督导年度跟踪报告。 3、本持续督导期间，保荐人通过与公司的日常沟通、现场回访等方式开展 持续督导工作，并于 2025 年 9 月 5 日对公司进行了现场检查。 1、保荐人制定了持续督导工作制度，制定了相应的工作计划，明确了现场 检查的工作要求。 4、本持续督导期间，保荐人根据相关法规和规范性文件的要求履行持续督 导职责，具体内容包括： 2、保荐人已与公司签订保荐协议，该协议已明确了双方在持续督导期间的 权利义务，并报上海证券交易所备案。 （1）查阅公司章程、三会议事规则等公司治理制度、三会会议材料； （2）查 ...

Investment Rating - The report maintains a "Market Weight" rating for the pharmaceutical and biotechnology industry, indicating that the industry is expected to perform within ±10% of the market index over the next six months [6][29]. Core Insights - The SW pharmaceutical and biotechnology industry underperformed the Shanghai and Shenzhen 300 index, with a gain of 1.36% from September 5 to September 18, 2025, lagging behind the index by approximately 1.66 percentage points [5][13]. - Most sub-sectors within the industry recorded positive returns during the same period, with the medical research outsourcing and medical equipment sectors leading with increases of 8.17% and 5.83%, respectively, while the chemical preparations sector saw a decline of 0.96% [5][14]. - Approximately 48% of stocks in the industry achieved positive returns, with notable performers including Zhendemedical, which had a weekly increase of 62.30% [15][18]. Summary by Sections 1. Market Review - The SW pharmaceutical and biotechnology industry underperformed the Shanghai and Shenzhen 300 index, gaining 1.36% from September 5 to September 18, 2025, which is 1.66 percentage points lower than the index [5][13]. - Most sub-sectors recorded positive returns, with medical research outsourcing and medical equipment sectors leading [5][14]. - About 48% of stocks in the industry recorded positive returns, with Zhendemedical showing the highest weekly increase [15][18]. - The overall industry valuation remained stable, with a PE ratio of approximately 56.10 times as of September 18, 2025, which is 4.26 times relative to the Shanghai and Shenzhen 300 index [19][29]. 2. Industry News - The report highlights the upcoming release of the 11th batch of national drug procurement rules, with discussions held on various aspects of the procurement process [6][27]. - The National Health Commission issued a notification regarding the 2025 version of medical quality control indicators, emphasizing the importance of a scientific and standardized quality control system [23][26]. 3. Company Announcements - Changchun High-tech announced a collaboration with Denmark's ALK-Abelló A/S for the development and commercialization of specific immunotherapy products in China [28]. 4. Weekly Industry Outlook - The report suggests maintaining a focus on investment opportunities in innovative drugs and sectors with expected business development catalysts, particularly in medical devices and pharmaceutical commerce [29][30].

Investment Rating - The report maintains a "Market Weight" rating for the pharmaceutical and biotechnology industry, indicating that the industry is expected to perform within ±10% of the market index over the next six months [36]. Core Insights - The SW pharmaceutical and biotechnology industry underperformed the CSI 300 index, with a gain of 1.36% from September 5 to September 18, 2025, lagging behind the index by approximately 1.66 percentage points [11]. - Most sub-sectors within the industry recorded positive returns during the same period, with the medical research outsourcing and medical equipment sectors leading with increases of 8.17% and 5.83%, respectively [12]. - Approximately 48% of stocks in the industry achieved positive returns, while 52% experienced negative returns during the reporting period [13]. - The overall industry valuation remained stable, with a PE (TTM) ratio of about 56.10 times as of September 18, 2025, and a relative PE to the CSI 300 of 4.26 times [17][27]. Summary by Sections Market Review - The SW pharmaceutical and biotechnology industry underperformed the CSI 300 index, with a 1.36% increase compared to the index's performance [11]. - Most sub-sectors recorded positive returns, particularly in medical research outsourcing and medical equipment [12]. - About 48% of stocks in the industry had positive returns, with notable performers and underperformers identified [13]. Industry News - The report highlights the upcoming release of the 11th batch of national drug procurement rules, with discussions on various aspects of the procurement process [25]. - The National Health Commission issued a notification regarding the 2025 version of medical quality control indicators, emphasizing the importance of a scientific and standardized quality control system [21][24]. Company Announcements - Changchun High-tech announced a collaboration with Denmark's ALK-Abelló A/S for the development and commercialization of specific immunotherapy products in China [26]. Industry Outlook - The report suggests focusing on investment opportunities in innovative drugs and sectors with expected business development catalysts, including medical devices and pharmaceutical commerce [27][28]. - Specific companies to watch include Mindray Medical, Yifeng Pharmacy, and Aier Eye Hospital, among others, due to their strong market positions and growth potential [29].

Core Insights - The export value of China's medical devices reached $24.1 billion in the first half of 2025, showing a year-on-year growth of 5.0% [1] - The revenue and net profit growth rates for Sci-Tech Innovation Board medical device companies were 9% and 3% respectively, with significant quarter-on-quarter increases in Q2 [1] - Nearly 30% of Sci-Tech Innovation Board medical device companies have over 30% of their business from overseas markets, indicating a trend towards internationalization [1] Group 1: Industry Growth and Internationalization - Sci-Tech Innovation Board medical device companies are focusing on high-value consumables and medical equipment, supported by capital market resources to build global marketing networks [2] - The industry is characterized by a strong emphasis on innovation, international expansion, and mergers and acquisitions, with approximately 18,000 invention patents held by these companies [2] - Leading companies like United Imaging and Mindray have made significant advancements in global markets, with United Imaging's overseas revenue increasing from less than 10% at the time of listing to nearly 20% in the first half of 2025 [3] Group 2: Mergers and Acquisitions - The medical device industry is seeing deep integration through mergers and acquisitions, with companies like Sanyou Medical successfully acquiring international firms to enhance their product lines and market reach [4] - Sanyou Medical's acquisition of the French company Implanet has significantly boosted its overseas revenue, with a reported 41.10% year-on-year growth in Q2 2025 [4] - The trend of mergers and acquisitions is supported by national policies aimed at fostering high-quality development in the medical device sector [6] Group 3: Performance of Key Players - Huatai Medical, a leader in electrophysiology and vascular intervention consumables, has seen increased market penetration and product coverage following the introduction of Mindray Medical as a major shareholder [5] - Companies like Sanyou Medical, Weigao Orthopedics, and Chuangli Medical reported net profit growth rates exceeding 40%, while micro-electrophysiology and Bairen Medical saw growth rates over 90% [5] - Nanwei Medical's acquisition of a Spanish company has further deepened its penetration into the European market, with overseas revenue increasing by 45% to 898 million yuan in the first half of 2025 [5]

Core Viewpoint - The article discusses the performance of the Kexin 50 ETF Enhanced (588450) on September 19, highlighting its opening price and the performance of its major holdings [1] Group 1: ETF Performance - Kexin 50 ETF Enhanced (588450) opened down 0.17% at 1.730 yuan [1] - Since its inception on May 6, 2024, the fund has achieved a return of 73.25% [1] - The fund's return over the past month is reported at 20.17% [1] Group 2: Major Holdings Performance - Major holdings include: - SMIC (中芯国际) up 0.70% [1] - Haiguang Information (海光信息) up 1.71% [1] - Lanke Technology (澜起科技) up 2.66% [1] - Zhongwei Company (中微公司) up 4.94% [1] - Kingsoft Office (金山办公) down 0.96% [1] - Cambrian (寒武纪) down 2.04% [1] - Transsion Holdings (传音控股) up 0.54% [1] - Zhongkong Technology (中控技术) down 0.31% [1] - Stone Technology (石头科技) unchanged [1] - United Imaging Healthcare (联影医疗) up 0.59% [1] Group 3: Management Information - The fund is managed by China Merchants Fund Management Co., Ltd. [1] - The fund manager is Deng Tong [1]

Group 1: Shanghai's Private Economy - The private economy in Shanghai plays a crucial role, contributing nearly 30% of the city's industrial output and fixed asset investment, and accounting for three-quarters of new employment in 2024 [1] - 80% of Shanghai's "specialized, refined, distinctive, and innovative" enterprises and "little giant" companies are private enterprises [1] Group 2: Embracing Change - Some Shanghai private enterprises are positioning themselves as "first movers" in their respective fields, such as Boxin Universe, which has successfully launched immersive experience projects [2] - The success of Boxin Universe's business model is attributed to breakthroughs in AI empowerment and equipment adaptability, allowing cultural and artistic resources to reach a global audience [2] Group 3: Digital Transformation - Black Lake Technology has assisted 30,000 factories in achieving digital transformation, becoming one of the largest industrial software developers in the Asia-Pacific region [3] - The increasing awareness of the importance of digital solutions among enterprises is a significant market opportunity for Black Lake Technology [3] Group 4: Industry Innovation and Collaboration - Union Medical, founded by Xue Min, has become a leading high-end medical equipment company in China, reversing the reliance on imported brands in the market [4] - Union Medical's products are now present in over 15,000 clinical and research institutions across nearly 90 countries, promoting the development of high-end medical equipment in China [4][5] - The collaboration with universities and hospitals enhances Union Medical's innovation capabilities, contributing to the establishment of a robust industrial innovation cluster [5] Group 5: Supportive Ecosystem - The supportive policies and healthy investment environment in Shanghai have been crucial for the rapid development of companies like He Yuan Bio, which has invested over 1.5 billion yuan in a new medical manufacturing base [6] - The integration of AI and practical applications is emphasized by companies like Xijing Technology, which is pioneering AI-driven solutions in complex environments such as airports [6]

Group 1 - Foreign institutions have shown high frequency and broad coverage in their research on A-share listed companies, with 415 foreign institutions conducting a total of 1,885 research sessions since the second half of the year [1][2] - Key sectors of focus for foreign institutions include industrial machinery, electronic components, integrated circuits, electronic instruments, and medical equipment, with companies like Huichuan Technology, Estun, Huaming Equipment, and Optoelectronics receiving over 80 research sessions each [1][2] - Notable foreign institutions such as Point72, Goldman Sachs, Bank of America Securities, and Citigroup have been particularly active, with Point72 leading with 63 research sessions [2] Group 2 - The current global political and economic uncertainties have increased investor interest in assets with higher certainty, with China being viewed as a stable environment with strong economic resilience [2][3] - Emerging trends such as the rise of new consumption, strong demand for export trade, and investments related to artificial intelligence (AI) are boosting market confidence in China's economic growth prospects [3] - Foreign institutions are optimistic about sectors like technology, high-end manufacturing, and healthcare, with a clear investment logic emerging in these areas [4] Group 3 - The healthcare equipment sector has also attracted significant attention from foreign institutions, driven by long-term growth factors such as an aging population and increased health awareness among residents [5] - Foreign institutions recognize the long-term growth resilience of the Chinese economy and the trend of industrial upgrading, capturing investment opportunities through in-depth research [6]