Investment Rating - The report maintains an "Outperform" rating for the following A-share targets: Jiangsu Heng Rui Medicine, Sichuan Kelun Pharmaceutical, Huadong Medicine, Jiangsu Nhwa Pharmaceutical, Xiamen Amoytop Biotech, Zhejiang Jingxin Pharmaceutical, Innovent Biologics, WuXi AppTec, Hangzhou Tigermed Consulting, Lepu Medical, MicroPort EP MedTech [5][36][8] - The report also maintains an "Outperform" rating for the following H-share targets: Hansoh Pharmaceutical Group, 3SBio, PATEO Biotech, Akeso, and related targets: Innovent Biologics, WuXi AppTec [8][36] Core Insights - The report continues to recommend the innovative drug and device industry and its supply chains, indicating a positive outlook for this sector [1][36] - In December 2025, the pharmaceutical sector underperformed the market, with the SW Pharmaceutical and Biological index falling by 4.1%, while the SHCOMP rose by 2.1%, ranking 26th among Shenwan primary industries [15][37] - The report highlights that the premium level of the pharmaceutical sector relative to all A-shares is currently at a normal level, with a relative premium rate of 63.2% as of the end of December 2025 [25][37] Summary by Sections A-Share Targets - The report includes a monthly portfolio of A-share targets that outperformed the pharmaceutical index, with a monthly average decline of 1.8% compared to the overall pharmaceutical index decline of 3.9% in December 2025 [11][36] - The top three stock gains in December 2025 were Luyan Pharma (+118.8%), CareRay Digital Medical Technology Co., Ltd. (+36.6%), and Hubei Hongyuan Pharmaceutical Technology Co., Ltd. (+34.0%) [24][37] H-Share Targets - The report notes that the Hong Kong stock pharmaceutical sector also underperformed the market, with the Hang Seng Healthcare index falling by 9.5% and the Hong Kong Biological Technology index falling by 10.6% in December 2025 [26][38] U.S. Market Performance - In December 2025, the U.S. pharmaceutical sector underperformed the market, with the S&P 500 Healthcare Select Sector declining by 1.5% while the S&P 500 fell by only 0.1% [26][39]

Group 1: Market Performance - The medical device ETF fund (159797) surged over 5% after four consecutive days of decline, indicating a significant rebound in the market [1] - The fund saw a net subscription of 6 million shares during the trading session, with a total inflow of over 30 million yuan in the past 10 days, including 7 days of net inflow [1] - Most component stocks of the medical device ETF fund performed positively, with notable gains including Lepu Medical reaching a 20% limit up, and other companies like United Imaging and Huatai Medical rising over 4% [1] Group 2: Neuralink and Brain-Computer Interface Developments - Neuralink is expected to enter large-scale production by January 1, 2026, with nearly automated surgical operations, enhancing safety by allowing guide wires to pass through the dura mater without opening it [4] - The advancement of Neuralink's technology is anticipated to facilitate collaboration with Tesla's Optimus humanoid robot, aiming to create a "human brain + robot" ecosystem [5] - The technology is transitioning from clinical trials to commercial viability, marking a significant step in making brain-computer interfaces widely accessible [3] Group 3: Policy and Industry Trends - The National Medical Products Administration (NMPA) emphasized the strategic importance of brain-computer interfaces in a meeting held on December 18, 2025, focusing on safety, innovation in regulatory methods, and collaboration across sectors [6] - Recent clinical trials have shown promising results for brain-computer interface systems, with successful implantations and significant improvements in patients' hand functions [6] - The rapid iteration and upgrade of brain-computer interface technology are driven by advancements in signal acquisition, materials science, and multi-modal integration, paving the way for broader applications beyond medical use [7]

Core Viewpoint - The medical device sector is experiencing significant growth, with notable stock increases for companies like Lepu Medical, Mindray, and United Imaging, driven by favorable regulatory developments and market sentiment [1][2]. Group 1: Stock Performance - Lepu Medical's stock surged by 20%, while Mindray and United Imaging saw increases of over 4% [1]. - Medical device-related ETFs rose by more than 5%, indicating strong investor interest in the sector [1]. Group 2: Regulatory Developments - The National Medical Products Administration has developed a "Priority Approval List for High-end Medical Devices (2025 Edition)," which includes advanced technologies such as medical electronic accelerators and implantable brain-machine interface devices [2]. - The inclusion of these high-end products in the priority approval category highlights the government's support for technological advancements in the medical device industry [3]. Group 3: Market Potential - The brain-machine interface sector is characterized by diverse application scenarios and rich research and development pathways, suggesting a broad potential market space [3]. - With supportive policies for product registration and medical insurance project approvals, the commercialization process for these technologies is expected to accelerate [3].

Group 1 - The core viewpoint of the news is that United Imaging Healthcare has shown significant financial performance with a notable increase in revenue and net profit, while also experiencing fluctuations in stock trading and financing activities [1][2][3] Group 2 - As of December 31, United Imaging Healthcare's stock price decreased by 1.27%, with a trading volume of 610 million yuan. The financing buy-in amount was 64.52 million yuan, while the financing repayment was 51.51 million yuan, resulting in a net financing buy-in of 13.01 million yuan. The total financing and securities balance reached 1.11 billion yuan [1] - The financing balance of United Imaging Healthcare is 1.11 billion yuan, accounting for 1.07% of the circulating market value, which is above the 80th percentile level over the past year, indicating a high level of financing activity [1] - On the short-selling side, 1,848 shares were repaid, and 3,000 shares were sold short on December 31, with a total short-selling amount of 376,500 yuan. The short-selling balance was 2,738,900 yuan, which is below the 20th percentile level over the past year, indicating a low level of short-selling activity [1] - As of September 30, the number of shareholders of United Imaging Healthcare reached 32,400, an increase of 96.28% compared to the previous period. The average circulating shares per person decreased by 29.23% to 25,444 shares [2] - For the period from January to September 2025, United Imaging Healthcare achieved an operating income of 8.859 billion yuan, representing a year-on-year growth of 27.39%. The net profit attributable to the parent company was 1.12 billion yuan, with a year-on-year increase of 66.91% [2] - Since its A-share listing, United Imaging Healthcare has distributed a total of 641 million yuan in dividends [3] - Among the top ten circulating shareholders as of September 30, 2025, Hong Kong Central Clearing Limited held 19.036 million shares, a decrease of 2.9809 million shares compared to the previous period. Other notable shareholders also saw reductions in their holdings [3]

截至2025年12月31日收盘，联影医疗(688271)报收于125.5元，下跌1.27%，换手率0.59%，成交量4.84万 手，成交额6.1亿元。 当日关注点 交易信息汇总资金流向 12月31日主力资金净流出1.17亿元，占总成交额19.12%；游资资金净流入6115.23万元，占总成交额 10.03%；散户资金净流入5542.54万元，占总成交额9.09%。 以上内容为证券之星据公开信息整理，由AI算法生成（网信算备310104345710301240019号），不构成 投资建议。 来自交易信息汇总：12月31日主力资金净流出1.17亿元，占总成交额19.12%。 来自公司公告汇总：联影医疗2025年第一次临时股东会审议通过关于2026年度日常关联交易预计 的议案，表决结果合法有效。 公司公告汇总上海市通力律师事务所关于上海联影医疗科技股份有限公司2025年第一次临时股东会的法 律意见书 上海市通力律师事务所就上海联影医疗科技股份有限公司2025年第一次临时股东会的召集和召开程序、 出席人员资格、表决程序及表决结果出具法律意见。本次股东会于2025年12月30日以现场和网络投票方 式召开，审议通过《关于 ...

Investment Rating - The industry investment rating is "Outperform the Market," indicating an expected performance that exceeds the market by more than 5% over the next six months [29]. Core Insights - The report highlights that the national government will continue to support the renewal of medical equipment in 2026, which is expected to drive demand in the medical device sector. The focus is on high-end equipment and companies with significant performance improvements and international expansion, such as Mindray Medical, United Imaging, Aohua Endoscopy, and Kaili Medical [3]. - The report emphasizes the optimization of application conditions and review processes for equipment renewal projects, aiming to lower investment thresholds and enhance support for small and medium-sized enterprises [3]. - The ongoing policy for equipment renewal is anticipated to sustain a favorable bidding environment for medical devices, with a gradual improvement in performance as inventory clears [3]. Summary by Sections Industry Overview - The report discusses the government's announcement on December 30, 2025, regarding large-scale equipment renewal and the inclusion of various sectors, including healthcare, in the support framework for 2026 [3]. - It outlines the measures to improve the application process for equipment renewal, including stricter requirements for equipment depreciation and minimum usage periods [3]. Investment Opportunities - The report suggests focusing on companies that are expected to show significant performance improvements and have a leading international presence in the medical device sector [3]. - Specific companies recommended for investment include Mindray Medical, United Imaging, Aohua Endoscopy, and Kaili Medical, which are well-positioned to benefit from the anticipated demand for high-end medical equipment [3]. Market Performance - The medical sector has experienced a decline, with a reported drop of 2.06% in the last week, ranking 25th among 28 industries [8][18]. - The report notes that the medical device market is under pressure in the short term due to policy impacts, but improvements are expected as companies innovate and expand internationally [5].

Investment Rating - The report maintains an "Overweight" rating for the innovative pharmaceutical and medical device industry chain [4][8]. Core Viewpoints - The report continues to recommend the innovative pharmaceutical and medical device industry chain, highlighting a selection of A-share and H-share stocks with an "Overweight" rating [2][8][11]. - The performance of the pharmaceutical sector in December 2025 was weaker than the broader market, with the SW Pharmaceutical Biotechnology index declining by 4.1% compared to a 2.1% increase in the Shanghai Composite Index [18][30]. - The report notes that the premium level of the pharmaceutical sector relative to the entire A-share market is currently at a normal level, with a relative premium rate of 63.2% as of December 31, 2025 [29][32]. Summary by Sections A-Share Recommendations - The report lists the following A-share stocks with an "Overweight" rating: - 恒瑞医药 (Hengrui Medicine) - 科伦药业 (Kelun Pharmaceutical) - 华东医药 (East China Pharmaceutical) - 恩华药业 (Enhua Pharmaceutical) - 特宝生物 (Tebao Biological) - 京新药业 (Jingxin Pharmaceutical) - 益方生物 (Yifang Biological) - 药明康德 (WuXi AppTec) - 泰格医药 (Tigermed) - 乐普医疗 (Lepu Medical) - 联影医疗 (United Imaging) - 微电生理 (Microelectrophysiology) [8][9]. H-Share Recommendations - The report maintains an "Overweight" rating for the following H-share stocks: - 翰森制药 (Hansoh Pharmaceutical) - 三生制药 (3SBio) - 科伦博泰生物 (Kelun-Botai Biological) - 康方生物 (CanSino Biologics) - 映恩生物 (InnoCare Pharma) - 百济神州 (BeiGene) [11][12]. Performance Analysis - The report indicates that the 国泰海通医药 monthly portfolio outperformed the pharmaceutical index in December 2025, with an average decline of 1.8% compared to a 3.9% decline in the overall pharmaceutical index [14][15]. - The report highlights the best-performing stocks in December 2025, with 泰格医药 (Tigermed) increasing by 11.2%, 特宝生物 (Tebao Biological) by 7.5%, and 惠泰医疗 (Huitai Medical) by 3.9% [15][18].

公司公告汇总 上海市通力律师事务所就上海联影医疗科技股份有限公司2025年第一次临时股东会的召集和召开程序、 出席人员资格、表决程序及表决结果出具法律意见。本次股东会于2025年12月30日以现场和网络投票方 式召开，审议通过《关于2026年度日常关联交易预计的议案》，关联股东已回避表决，并对中小投资者 投票情况单独统计。表决结果合法有效。 联影医疗2025年第一次临时股东会决议公告显示，会议由董事会召集，董事TAO CAI主持，采用现场与 网络投票结合方式，出席股东所持表决权占公司总表决权的36.8981%。议案对中小投资者单独计票， 表决结果合法有效。上海市通力律师事务所确认会议召集、召开程序及表决结果合法有效。 以上内容为证券之星据公开信息整理，由AI算法生成（网信算备310104345710301240019号），不构成 投资建议。 截至2025年12月26日收盘，联影医疗（688271）报收于130.32元，较上周的127.34元上涨2.34%。本 周，联影医疗12月26日盘中最高价报130.98元。12月24日盘中最低价报124.83元。联影医疗当前最新总 市值1034.32亿元，在医疗器械板块市 ...

Core Viewpoint - The A-share pharmaceutical sector in 2025 exhibits structural differentiation, with innovative drugs and CXO sectors thriving due to overseas demand and business development, while traditional Chinese medicine, medical devices, and pharmaceutical commerce face performance pressures [3][20]. Summary by Category Overall Market Performance - The A-share pharmaceutical and biotechnology sector saw an overall increase of 25.64% from January 1 to December 30, 2025, despite a slight decline in revenue and a stabilization in profits, with total revenue of 18,544.52 billion yuan, down 1.42% year-on-year, and net profit of 1,407.32 billion yuan, down 1.65% year-on-year [4][21]. Innovative Drug Sector - The innovative drug sector was a standout performer in 2025, with the chemical pharmaceutical segment rising by 32.58% and the medical services segment by 32.91% [4][21]. - Companies like BeiGene (百济神州) reported significant growth, achieving revenue of 27.595 billion yuan, a 44.2% increase year-on-year, surpassing the total revenue of 27.21 billion yuan for 2024 [4][22]. Business Development (BD) Trends - The business development landscape for innovative drug companies is evolving, with significant partnerships such as the 11.4 billion USD deal between Innovent Biologics and Takeda, and a 12.5 billion USD collaboration between Hengrui Medicine and GlaxoSmithKline [5][22][24]. - The total value of business development transactions reached approximately 94.158 billion USD in the first three quarters of 2025, significantly exceeding the total for 2024 [25]. CXO Sector Performance - The CXO sector, driven by the demand for innovative drug research, achieved a 32.91% increase in 2025, with total revenue of 1,365.72 billion yuan, up 3.63% year-on-year, and net profit of 209.12 billion yuan, up 36.47% year-on-year [10][27]. - Leading companies like WuXi AppTec (药明康德) and Kanglong Chemical (康龙化成) returned to growth, with WuXi AppTec reporting a revenue increase of 18.61% and net profit growth of 84.84% [28][31]. Traditional Chinese Medicine and Medical Devices - The traditional Chinese medicine sector experienced a modest increase of 6.75% in 2025, with total revenue of 2,590.69 billion yuan, down 4.33% year-on-year, and net profit of 294.99 billion yuan, down 1.53% year-on-year [36]. - The medical device sector reported a revenue of 1,792.10 billion yuan, down 2.24% year-on-year, with notable performance differences among sub-sectors, where companies like Mindray Medical (迈瑞医疗) showed strong overseas revenue growth [33][34].

Group 1 - The core viewpoint of the news is that United Imaging Healthcare experienced a decline in stock price, closing at 125.81 CNY per share, with a market capitalization of 103.69 billion CNY as of December 31 [1] - United Imaging Healthcare, established on March 21, 2011, specializes in high-performance medical imaging equipment, radiation therapy products, life science instruments, and digital healthcare solutions [1] - The company's revenue composition includes 81.29% from sales of medical imaging diagnostic and radiation therapy equipment, 13.56% from maintenance services, 4.68% from other sources, and 0.47% from software [1] Group 2 - According to data, a fund under Bank of China holds a significant position in United Imaging Healthcare, with a reduction of 66,100 shares in the third quarter, leaving 47,700 shares, which represents 3.51% of the fund's net value [2] - The estimated floating loss for the fund on the current day is approximately 62,000 CNY [2] Group 3 - The Bank of China’s fund, the Zhongyin SSE Sci-Tech 50 ETF, was established on March 27, 2025, with a current size of 206 million CNY and a return of 36.9% since inception [3] - The fund manager, Zhao Jianzhong, has been in position for 10 years and 210 days, overseeing total assets of 5.22 billion CNY, with the best return during his tenure being 130.53% and the worst being -31.32% [3]