21世纪经济报道记者 韩利明 上海报道 日前，华熙生物在官微发布《概念总在重演，科技永远向前》一文，直指资本市场不断追求新的公司题 材，为了营造比透明质酸产业更大的预期，围绕某重组胶原企业的研报中，出现了大量直接针对中国透 明质酸产业的"对比研究"。 一时间，有关"透明质酸（玻尿酸）与重组胶原蛋白""华熙生物'炮轰'券商"的讨论持续发酵。 5月21日晚间，华熙生物再次发文回应，坦言作为在资本市场经历过第一轮完整周期的企业，深切体会 概念切换对企业经营带来的影响，"正是因为现在经营环境面临挑战，华熙生物才会更多体会到行业中 众多企业的难处，才会有新的角度审视产业的生态环境，才会与所有的同行一起审视这个环境有哪些因 素在鼓励价值创造，有哪些是在导致价值损耗。" 不可否认，自2022年登顶业绩巅峰后，华熙生物近两年来直面营收和净利润双降的压力，2024年更是启 动一次包括业务流程重塑、组织与人才变革、指标与绩效体系变革、推动企业数智化等多个项目在内的 全面的管理变革。 在此背景下，这场关于产业生态中"资本逐利"与"科技长期主义"的公开博弈，也是对行业发展逻辑的深 层叩问。摆脱概念炒作窠臼，以技术壁垒构建可持续的产业 ...

5月21日晚间，华熙生物官方公众号发布消息，再次就透明质酸、重组胶原蛋白等问题进行回应。 在谈到对透明质酸市场的现在和未来看法时，华熙生物表示，任何产业领域都有一个共同点：当某一领域展现出良好 的赚钱效应后就会吸引大量资本和企业涌入，随之引发价格和利润的下滑。这个现象在透明质酸领域发生过，在其他 任何领域都会发生。 但并非所有的企业都会在低端竞争，华熙生物的进阶道路并非特殊，是在中国很多企业中发生过的，这就是进入高端 透明质酸市场，做精做深，做出新的延伸和高度。在医用和试验用的高端透明质酸和生物制造领域，华熙生物依靠健 全的酶库和全球最大的中式转化平台，占据着高端市场技术与品牌的制高点，并依靠透明质酸打开了庞大的糖生物产 业和细胞生物学的认知窗口。 对于如何看待重组胶原蛋白，华熙生物方面指出，首先，就像不能比较肝脏与肾脏孰强孰弱一样，在很多场景下，也 无法比较透明质酸（HA）与胶原蛋白孰强孰弱。透明质酸和胶原蛋白都是人体重要的物质，透明质酸与胶原蛋白的 互动，构成了细胞外基质ECM功能的核心，这两个物质形成了信号共生、力学共生、病理共损的三重关系： 1、在力学层面，HA凭借其卓越的高保水性和粘弹性，在细胞外基 ...

Core Viewpoint - Huaxi Biological (688363.SZ) criticizes certain brokerage reports for misleading the market regarding the hyaluronic acid (HA) industry, claiming that these reports promote the idea that HA is outdated and misrepresent its value compared to recombinant collagen [1][2][5] Group 1: Criticism of Brokerage Reports - Huaxi Biological specifically names brokerages such as Western Securities, Anxin Securities, and Xinda Securities, accusing them of publishing misleading conclusions that favor recombinant collagen over hyaluronic acid [1][2][4] - The company argues that these reports distort scientific facts and mislead consumers, damaging the trust in the Chinese biotechnology and medical aesthetics industry [1][6] - Huaxi Biological emphasizes the importance of maintaining a fair competitive environment and the integrity of scientific information in the industry [1][6] Group 2: Market Dynamics and Competition - The criticism from Huaxi Biological is seen as a response to the rising competition from Juzhi Biological (02367.HK), which focuses on recombinant collagen and has been gaining market traction [1][8][12] - Huaxi Biological's performance has been declining, with projected revenues and net profits for 2024 showing significant decreases compared to previous years, while Juzhi Biological has experienced substantial growth [10][12] - The company highlights that the narrative of HA being outdated is a construct of "restless capital" aiming to shift focus to new market trends, which undermines the established value of HA [13][14] Group 3: Industry Support and Response - Following Huaxi Biological's statements, two industry associations, the China Fragrance and Cosmetic Industry Association and the China Aesthetic Medicine Association, issued a joint initiative advocating for scientific integrity and ethical marketing practices [7] - Huaxi Biological reports that many institutions have retracted erroneous reports and some have issued apologies, indicating a recognition of the misleading nature of the previous analyses [6][12] - The company maintains ongoing communication with brokerage firms regarding the accuracy of research reports and their implications for the industry [6][12]

Core Viewpoint - The article discusses the conflict between Huaxi Biological and several brokerage firms regarding the comparison of hyaluronic acid and recombinant collagen protein, with Huaxi asserting that the notion of hyaluronic acid being outdated is misleading and driven by "restless capital" [1][7]. Company Overview - Huaxi Biological specializes in hyaluronic acid-related products and has faced significant stock price and market capitalization declines since reaching a peak in July 2021, with its stock price dropping from 313.1 yuan to 52.61 yuan as of May 21, 2023, resulting in a market cap reduction from over 1500 billion yuan to 253 billion yuan [2][8]. - The company has reported continuous revenue declines, with revenues of 60.76 billion yuan and 53.71 billion yuan for 2023 and 2024, respectively, representing year-on-year decreases of 4.45% and 11.61% [10]. Industry Dynamics - The market has seen a shift in focus towards recombinant collagen protein, with companies like Juzhi Biological and Jinbo Biological experiencing significant stock price increases and revenue growth, contrasting with Huaxi's struggles [2][13]. - The recombinant collagen protein market in China is projected to grow at a compound annual growth rate of 44.93%, reaching 585.7 billion yuan by 2025 [7]. Performance Comparison - Juzhi Biological's revenues for 2022, 2023, and 2024 were 23.75 billion yuan, 35.26 billion yuan, and 55.39 billion yuan, respectively, with year-on-year growth rates around 50% [13]. - Jinbo Biological's revenues during the same period were 3.9 billion yuan, 7.8 billion yuan, and 14.43 billion yuan, with growth rates of 67.15%, 99.97%, and 84.92% [13]. Regulatory and Market Response - Huaxi Biological has reported the brokerage firms to the China Securities Regulatory Commission for allegedly misleading reports that could distort market perceptions [1][3]. - The company has emphasized the need for a healthy industry ecosystem and has engaged with industry associations to advocate for a return to scientific principles in the market [5][7].

Core Viewpoint - Huaxi Biological has publicly criticized several securities firms for promoting collagen products and suggesting that hyaluronic acid is "outdated," indicating a defensive stance amid declining performance and market competition [1][2][3] Company Performance - Huaxi Biological started with hyaluronic acid and holds nearly 50% of the global market share, expanding into medical products, skincare, and functional foods [5][6] - Despite maintaining positive growth during the pandemic years of 2020 and 2021, the company's revenue and profit have declined since 2021, with net profits projected to drop from 9.71 billion yuan in 2022 to 1.74 billion yuan in 2024 [10] - The company's market capitalization has plummeted from over 140 billion yuan in 2021 to 25.3 billion yuan as of May 21, 2025 [10] Market Comparison - In contrast, competitors like Juzhi Biological and Jinbo Biological have seen significant growth, with Juzhi's net profits increasing from 1 billion yuan in 2022 to 20.62 billion yuan in 2024, and Jinbo's from 1.09 billion yuan to 7.31 billion yuan in the same period [14] - Both companies have also achieved substantial stock price increases, with market capitalizations of 87.5 billion HKD and 51.1 billion yuan, respectively [14] Industry Dynamics - The rise of collagen products has created a competitive threat to hyaluronic acid, with market trends favoring new ingredients [15][18] - The demand for collagen is expected to exceed supply, with projections indicating a production of 200,000 tons against a demand of over 220,000 tons by 2025 [19] Challenges Ahead - Despite Huaxi's efforts to defend hyaluronic acid, the company faces challenges due to internal management issues and a tarnished brand image, which may hinder future sales growth [20][21] - The company's recent foray into collagen products has not yet shown significant revenue impact, suggesting ongoing struggles in adapting to market changes [21]

炒股就看金麒麟分析师研报，权威，专业，及时，全面，助您挖掘潜力主题机会！ 【文/王力 编辑/周远方】 5月17日晚间，华熙生物通过其官方公众号发布《概念总在重演，科技永远向前》一文，文章剑指华泰 证券、安信证券等多家头部券商，指控其通过发布存有偏颇的"对比研究"为同业竞品巨子生物造势，蓄 意贬低透明质酸（玻尿酸）的行业价值。 据该篇檄文披露，相关券商研报通过刻意构建的论证框架，系统性输出"透明质酸技术过时论""胶原蛋 白安全性优势论"等争议性观点，更将透明质酸产业价值置于胶原蛋白之下。 这场罕见的公开呛声事件，将华熙生物与巨子生物的角力推至台前，同时引发业界对生物活性材料及资 本介入产业竞争的多维探讨。 百元玻尿酸时代下，资本市场的题材切换 截图来自 华熙生物公众号 从成分来看，玻尿酸（透明质酸）是一种天然多糖，通过微生物发酵生产，具有超强锁水能力，其核心 功能在于填充塑形与保湿，适用于鼻部、下巴等立体部位，且可通过溶解酶快速逆转效果，安全性较 高。 早在2015年干细胞概念受资本热捧时，玻尿酸就曾被贴上"技术落后"的标签。历史轮回中，相似的剧本 正在重组胶原蛋白领域重演。 近日，华熙生物在公众号发文中更是将 ...

作者 | 远禾 数据支持 | 勾股大数 据（www.gogudata.com） 昔日千亿巨头，华熙生物，急了。 最近，华熙生物发布了名为《概念总在重演，科技永远向前》的文章，节选了华泰证券、安信证券、西部证券等多家券商的研报，抨击这些券商 对于 "玻尿酸过时" 的市场观点。 在华熙生物发文的背后，是近几年来玻尿酸概念和重组胶原蛋白概念的对垒。 2019年上市以来，华熙生物顶着"医美茅"的名头，股价一度上涨至309元/股，市值超过1400亿元。 然而 2021年之后，华熙生物股价急转直下，至今已暴跌超80%，跌去超千亿市值，仅剩200多亿元。在近期医美板块的暴涨之中，华熙生物也 成为逐渐掉队的一批。 与之形成鲜明对比的是，北交所目前市值第一的锦波生物， 2023年北交所上市以来股价已经上涨超10倍，市值近500亿元。 目前，锦波生物股价已经超过 500元/股，仅次于贵州茅台和寒武纪。 如果从锦波生物 2015年在新三板挂牌时的最低价算起，锦波生物在这10年里更是已经暴涨约85倍。 因此，华熙生物这次声势浩大的 "指控"，更像是华熙生物为"玻尿酸"（也称"透明质酸"）概念的一次背书。 一边是狂涨40倍的重组胶原蛋 ...

Core Viewpoint - The article highlights a conflict in the biopharmaceutical industry regarding the competition between hyaluronic acid and recombinant collagen, with Huaxi Biological criticizing the notion that hyaluronic acid is outdated, which they attribute to capital-driven speculation [1][4]. Company Performance - Huaxi Biological's performance has declined significantly, with projected revenue for 2024 expected to decrease by 11.61% and net profit to drop by 70.59%, resulting in a market capitalization loss of over 100 billion [1][6]. - In contrast, Juzhi Biological has experienced substantial growth, with a projected revenue increase of 57.2% and net profit growth of 42.4% for 2024, leading to a doubling of its market capitalization [1][6]. Market Dynamics - The article discusses the contrasting market performances of Huaxi Biological and Juzhi Biological, indicating a clear divide in the industry, with Huaxi's stock price falling over 80% from its peak of 309.43 yuan per share in July 2021 to 53.08 yuan per share as of May 20, 2025, resulting in a market cap of less than 25.6 billion [9][6]. - Juzhi Biological's stock has seen a significant increase, reaching a peak of 86.45 HKD, representing a cumulative rise of over 44% from approximately 60 HKD at the end of 2024 [8][6].

近日，华熙生物官方微信号发布了一篇题为《概念总在重演，科技永远向前》的文章，与一般的宣传自 身产品，阐述自身投资价值的文章不同，这篇文章则是公开炮轰多家券商为"港股重组胶原蛋白第一 股"巨子生物站台，宣扬透明质酸钠"过时论"，引发市场广泛关注。 这件事情的起因，还要从多家券商对于巨子生物发布的研报说起。华熙生物作为全球领先的透明质酸原 料生产商，曾凭借玻尿酸在美妆护肤行业占据重要地位，被誉为"医美茅"。然而，在官方微信号的文章 中，华熙生物却指出，近年来随着重组胶原蛋白概念的兴起，部分券商发布研报宣扬玻尿酸"过时论"， 为巨子生物等重组胶原蛋白企业站台。华熙生物认为这些观点是一场"谎言"，是"浮躁资本"构建的题材 幻象，严重伤害了透明质酸产业的市场基础，还导致公司股价大跌，业绩也受到了一定影响。 券商发布的相关研报截图来源：华熙生物官方微信号 两者股价背道而驰的背后，是两者业绩的此消彼长，2024年，华熙生物交出了上市以来最差成绩单，全 年营收53.71亿元，比上年同期下降11.6%；归母净利润1.64亿元，同比大幅下降72.27%。2022—2024年 净利润更是从9.71亿元降至1.74亿元，缩水82%。 ...

Core Viewpoint - The article discusses the ongoing debate regarding the relevance of hyaluronic acid (HA), with Huaxi Biotech refuting claims that HA is outdated and emphasizing its continued importance in life sciences research [1][2]. Group 1: Market Perspective - Huaxi Biotech directly addresses nine brokerage firms that have published reports suggesting that hyaluronic acid is becoming obsolete, labeling this perspective as a product of "restless capital" creating a false narrative [1]. - The company argues that the rise of the "outdated hyaluronic acid" theory is fundamentally a misrepresentation of a substance that has been central to life sciences for millions of years [1]. Group 2: Research and Development - Since the discovery of HA, the number of related studies has been increasing annually, with a significant surge post-2010, where over 60% of research focuses on cutting-edge areas such as immunity, metabolism, and cell differentiation [1]. - Huaxi Biotech's breakthrough enzyme cutting technology in 2011 has significantly advanced research on hyaluronic acid in fields like cancer, aging, and immunity [1]. Group 3: Future Outlook - The company expresses its commitment to leveraging its foundation in the sugar biology industry to explore deeper realms of life sciences, asserting that hyaluronic acid will always be their starting point [2]. - Huaxi Biotech emphasizes the importance of protecting the industry built over generations and is open to discussions on optimizing scientific and industrial ecosystems [2].