中国经济网北京11月3日讯 安徽省药品监督管理局官网近期发布第一分局化妆品生产监督检查信息通告（2025年第5期）。 （责任编辑：徐自立） | 序号 | 检查时间 | 企业名称 | 生产地址 | 椅查范围 | 检查依据 | 检查结论 | 处理措施 | 备注 | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | | | 安徽省合肥经济技 | | 《化妆品监督管理条例》《化 妆品生产质量管理规范 » 《化 | 基本符合(生 | | | | 1 | 2025年9月4日 | 联合利益(中 | 术开发区锦绣大道 | 般液态单元、青霜乳液 | 妆品生产质量管理规范检查要 | 产质量管理体 | 限期營改 | 元 | | | | 国)有限公司 | 88号 | 单元、牙膏单元 | 点及判定原则》《化妆品检查 | 系存在缺陷) | | | | | | | | | 管理办法》等。 | | | | | 2 | | 联合利华(中 | 安徽省合肥经济技 | | 《化妆品监督管理条例》《化 妆品生产质量管理规范 » 《化 | | | 无 | | | 2025年9月4日 ...

Investment Rating - The investment rating for the company is upgraded to "Accumulate" [1] Core Insights - The company reported a 10.5% year-on-year increase in net profit attributable to the parent company for Q3 2025, indicating effective operational adjustments [7] - The company has experienced a significant improvement in profitability, with a notable recovery trend in profits over the last two quarters [7] - Strategic investments in Saint Pharma and international collaborations are expected to enhance long-term growth prospects [7] Financial Performance Summary - For Q1-Q3 2025, the company achieved total revenue of 3.16 billion, down 18.4% year-on-year, and a net profit of 250 million, down 30.3% year-on-year [7] - In Q3 2025, the company reported revenue of 900 million, a decrease of 15.2% year-on-year, but a net profit of 31.53 million, an increase of 55.6% year-on-year [7] - The gross profit margin for Q1-Q3 2025 was 70.7%, a decrease of 3.2 percentage points year-on-year, while the gross profit margin for Q3 2025 was 69.9%, a decrease of 2.5 percentage points year-on-year [7] - The company’s operating expenses ratio decreased by 4.9 percentage points year-on-year in Q3 2025, with the sales expense ratio reaching its lowest level in five years [7] Earnings Forecast and Valuation - The forecast for net profit attributable to the parent company has been revised down from 720 million and 860 million for 2025 and 2026 to 380 million and 520 million, respectively [7] - The new forecast for 2027 net profit is 620 million, with corresponding P/E ratios of 69, 50, and 42 for 2025, 2026, and 2027 [7]

Core Viewpoint - The article discusses the strategic transformation of the brand Quadi, emphasizing its emotional connection with consumers and the introduction of the CT50 patented technology for anti-aging skincare, which is positioned as a "cell charger" for skin health [2][12][38]. Group 1: Brand Transformation - Quadi has appointed Yang Tianzhen as its brand energy ambassador, launching the slogan "Use Quadi to Avoid Collapse," which resonates emotionally with consumers sharing their personal stories of resilience [2][4]. - The brand has undergone a comprehensive renewal over the past year, focusing on brand value propositions, scientific positioning, and narrative development [4][12]. - Quadi's brand narrative has evolved to emphasize "energy skincare," aligning with consumer preferences for scientific and effective skincare solutions [27][34]. Group 2: Market Challenges - Huaxi Biological, Quadi's parent company, has faced challenges in the efficacy skincare market despite high R&D investment, with R&D expenses rising from 6.15% in 2020 to 10.22% by mid-2025, totaling 1.977 billion yuan over five years [6][9]. - Consumer behavior has shifted, with over 80% prioritizing "ingredients and efficacy" over "brand recognition," necessitating clear differentiation in market positioning [9][12]. Group 3: CT50 Technology - The CT50 technology, developed from Huaxi Biological's acquisition of RevitaCare Lab, focuses on non-crosslinked hyaluronic acid and aims to create a favorable environment for cell health [20][22]. - CT50 combines various active ingredients into three functional packages: cell nutrition support, signal enhancement, and mitochondrial energy remodeling, forming a comprehensive "cell charging solution" [25][26]. - The technology is positioned as a key competitive advantage for Quadi, leveraging Huaxi Biological's extensive research capabilities and infrastructure [26][38]. Group 4: Brand Narrative Framework - Quadi's new narrative framework consists of four dimensions: personal growth, technological innovation, women's empowerment, and authentic user experiences, enhancing consumer engagement [27][28]. - The brand's archetype has shifted from "Caregiver" to include "Hero," reflecting a strategic upgrade to position itself as a solution provider against aging and stress [34][35]. - This transformation aims to establish Quadi as a "cell anti-aging expert" in consumers' minds, aligning with the industry's trend towards science-driven branding [38][41].

Core Viewpoint - The company reported a decline in revenue and net profit for the first three quarters of 2025, with revenue at 3.16 billion and net profit at 250 million, reflecting year-on-year decreases of 18.4% and 30.3% respectively [1] Group 1: Financial Performance - In Q1, Q2, and Q3 of 2025, the company achieved revenues of 1.08 billion, 1.18 billion, and 900 million respectively, with year-on-year declines of 20.8%, 18.4%, and 15.2% [1] - The net profit for Q1, Q2, and Q3 of 2025 was 100 million, 120 million, and 30 million respectively, showing a year-on-year change of -58.1%, +20.9%, and +55.6% [1] - The gross profit margin for the first three quarters of 2025 was 70.7%, a decrease of 3.2 percentage points year-on-year, while the gross profit margin for Q3 2025 was 69.9%, down 2.5 percentage points year-on-year [3] Group 2: Business Segments - The raw materials business showed steady growth, with a revenue increase of 2.69% year-on-year in Q3 2025, and a high gross margin of 84.8%, indicating strong core barriers in high-end raw materials [2] - The medical terminal business achieved revenue of 359 million in Q3 2025, a year-on-year increase of 14.51%, with the medical beauty segment contributing 229 million, up 7.88% [2] - The skin science innovation transformation business is in a deepening transition phase, with a nearly 10 percentage point decrease in sales expense ratio in Q3 2025, leading to improved overall operational quality [2] Group 3: Strategic Initiatives - The company is transitioning its brand communication from a "scale-oriented" approach to an "efficiency-oriented" one, resulting in a significant reduction in sales expense ratio [4] - The company is actively pursuing external growth, including strategic placements in companies like Saint Pharma and He Yuan Bio, to expand its product offerings in the field of small nucleic acid drugs and plant-based bioactive products [4] - The company is enhancing its global research collaborations, with strategic partnerships established for ECM-related research and joint development projects in PDRN with leading international medical beauty firms [4] Group 4: Future Outlook - The company has adjusted its net profit forecasts for 2025-2027 to 380 million, 540 million, and 720 million, reflecting downward revisions of 19%, 9%, and 10% respectively [5] - The company is recognized as a leading player in the ECM field, with a strong emphasis on foundational research and product synergy, maintaining a "buy" rating despite current challenges [5]

Investment Rating - The investment rating for the company is "Accumulate" (maintained) [2] Core Views - The company has shown continuous improvement in profitability in Q3 2025, with expectations for operational flexibility to be released [8] - The company achieved a revenue of 3.163 billion yuan in the first three quarters, a year-on-year decrease of 18.4%, and a net profit attributable to shareholders of 252 million yuan, down 30.3% [8] - The company anticipates a rebound in performance due to the improvement in its skin care business [8] Financial Performance Summary - Revenue for 2023 is projected at 6.076 billion yuan, with a decline of 4.5% year-on-year, and a net profit of 593 million yuan, down 39.0% [7] - The company expects net profits to recover to 411 million yuan in 2025, with a projected PE ratio of 62.7 [8] - The gross profit margin for Q3 2025 was 69.9%, a decrease of 2.5 percentage points [8] Business Segments Summary - The raw materials segment generated revenue of 923 million yuan in the first three quarters, with a gross margin of 84.81% [8] - The medical terminal segment saw a revenue increase of 14.5% in Q3 2025, with the medical beauty business contributing 229 million yuan [8] - The nutrition science business achieved its first quarterly profit while maintaining revenue growth [8] Future Outlook - The company forecasts net profits of 4.11 billion yuan, 5.09 billion yuan, and 5.74 billion yuan for 2025, 2026, and 2027 respectively, with corresponding PE ratios of 62.7, 50.7, and 44.9 [8]

Core Insights - The 2025 High-Quality Development Forum for Listed Companies and the 27th Golden Bull Award Ceremony took place in Nantong, Jiangsu, highlighting the theme "Moving Towards New Horizons for a Sustainable Future" [1] - Huaxi Biological, established in 2000, is recognized as a global leader in biotechnology and biomanufacturing, focusing on innovative solutions in aging intervention and tissue regeneration [1] - The Golden Bull Award, initiated in 1999 by China Securities Journal, aims to create a transparent and credible platform for recognizing outstanding listed companies in China's capital market [1] Company Overview - Huaxi Biological has built the world's largest synthetic biological manufacturing platform, offering integrated solutions across pharmaceuticals, medical aesthetics, nutritional science, and dermatology [1] - The company has developed several brands, including Runbaiyan, Kuaidi, Mibeier, Jihuo, and Huaxi Dangkang, showcasing its diverse product offerings [1] Award Details - The Golden Bull Award includes nine categories, such as "Most Investment Value Award," "Golden Bull Outstanding Entrepreneur Award," and "Golden Bull Secretary Award," recognizing excellence in corporate governance and investor relations [2] - The "Golden Bull Secretary Award" specifically honors company secretaries who excel in governance, equity management, information disclosure, and investor relations [2]

Core Viewpoint - The medical beauty sector experienced a slight increase of 0.81% on October 31, with Jinbo Biological leading the gains, while the overall market indices saw declines [1]. Group 1: Market Performance - On October 31, the Shanghai Composite Index closed at 3954.79, down 0.81%, and the Shenzhen Component Index closed at 13378.21, down 1.14% [1]. - Jinbo Biological's stock price rose by 2.35% to 251.28, with a trading volume of 16,800 hands and a transaction value of 421 million yuan [1]. - Other notable stocks in the medical beauty sector included *ST Meigu, which increased by 1.42% to 3.58, and Huaxi Biological, which rose by 0.82% to 66.65 [1]. Group 2: Capital Flow - The medical beauty sector saw a net inflow of 5.8151 million yuan from institutional investors, while retail investors experienced a net outflow of 7.1663 million yuan [2]. - The sector also recorded a net inflow of 1.3512 million yuan from speculative funds [2].

Core Viewpoint - The performance of Bloomage Biotechnology, a leading hyaluronic acid company, continues to be negatively impacted by the ongoing transformation pains in its skin science innovation business, with a significant decline in revenue and mixed profit results in the third quarter of 2025 [1]. Financial Performance - In Q3 2025, the company reported revenue of 903 million yuan, a year-on-year decrease of 15.16%, while net profit attributable to shareholders increased by 55.63% to 31.53 million yuan [1][3]. - For the first three quarters of 2025, revenue decreased by 18.36% to 3.163 billion yuan, and net profit fell by 30.29% to 252 million yuan [1]. Business Segment Analysis - The skin science innovation business has been a major drag on the company's performance, with revenue from this segment declining significantly [4]. - In 2022, the functional skincare business peaked with revenue of 4.607 billion yuan, but in 2023, it showed signs of fatigue, with a year-on-year decline of 18.45% to 3.757 billion yuan [5]. - The skin science innovation business's revenue for 2024 was 2.569 billion yuan, down 31.62%, accounting for 47.92% of the company's main business revenue [5]. Strategic Adjustments - The company has made strategic adjustments to focus on core brands and reduce non-essential brand incubation plans, aiming to strengthen the integration of technological achievements with consumer products [6]. - In Q3 2025, the sales expense ratio dropped to 34.26%, the lowest in five years, due to optimized brand communication and channel structure [6]. Asset Impairment and Investments - The company reported significant asset impairment losses in Q3 2025, totaling 23.25 million yuan, which did not affect the overall profit and loss situation [8]. - Bloomage Biotechnology has made strategic investments in the biopharmaceutical sector, including a 138 million HKD subscription for shares in Saintno Pharmaceuticals, aiming to explore collaboration opportunities [9]. - The company also participated in a strategic placement for Heyuan Biotechnology, investing 20 million yuan, focusing on plant-based bioactive substances [10].

Core Viewpoint - The article discusses the challenges faced by Huaxi Biological, particularly its declining performance and the strategic changes initiated by its founder Zhao Yan to revitalize the company after a period of poor financial results [5][19]. Financial Performance - In the first three quarters of 2025, Huaxi Biological reported revenue of 3.163 billion yuan, a year-on-year decrease of 18.36%, and a net profit attributable to shareholders of 252 million yuan, down 30.29% year-on-year [5]. - The decline in profit is attributed to the drop in revenue from the skin science innovation transformation business, previously known as functional skincare products [5][10]. - Despite the overall decline, there was a notable improvement in the second quarter of 2024, with net profit increasing by 20.89% year-on-year, marking the first growth since the second quarter of 2024 [5][6]. Strategic Changes - Zhao Yan returned to the operational front line in March 2024, initiating a comprehensive reform of the company's management, sales expenses, and strategic direction [5][19]. - The company has reduced its sales expense ratio to 34.26%, the lowest in five years, by cutting costs in marketing and promotional activities [6]. - Huaxi Biological is undergoing a transformation process that includes organizational restructuring, talent system adjustments, and marketing model innovations [7][19]. Market Context - The medical beauty market is rapidly changing, with Huaxi Biological's market value dropping significantly from nearly 150 billion yuan at its peak in July 2021 to 25.977 billion yuan by October 29, 2024 [9]. - The stock price has also seen a dramatic decline, falling over 82% from its historical high of 312.99 yuan per share [9][10]. - The emergence of collagen peptide products has shifted investor focus away from hyaluronic acid, leading to a decline in Huaxi Biological's market position [12][13]. Competitive Landscape - Other companies in the hyaluronic acid sector, such as Haohai Biological and Aimeike, have also experienced significant stock price declines, indicating a broader trend in the market [11]. - New entrants focusing on collagen products have gained traction, with companies like Juzhibio and Jinbo Biological reporting substantial revenue growth, further challenging Huaxi Biological's market share [12][13]. Product Performance - The functional skincare product line, once a growth driver, has seen revenue declines exceeding 15% year-on-year in recent quarters, significantly impacting overall performance [6][13]. - The revenue from key brands like Runbaiyan and Kuaidi has also decreased, with projections indicating further declines in 2024 [21].

Core Insights - The medical beauty sector experienced a decline of 0.81% on October 30, with Jinbo Biological leading the drop at 7.07% [1] - The Shanghai Composite Index closed at 3986.9, down 0.73%, while the Shenzhen Component Index closed at 13532.13, down 1.16% [1] Medical Beauty Sector Performance - Huaxi Biological closed at 53.55, down 0.70%, with a trading volume of 30,900 shares and a transaction value of 166 million [1] - *ST Meigu closed at 3.53, down 0.84%, with a trading volume of 71,000 shares and a transaction value of 25.09 million [1] - Aimeike closed at 158.89, down 0.89%, with a trading volume of 30,100 shares and a transaction value of 47.9 million [1] - Jinbo Biological closed at 245.50, down 7.07%, with a trading volume of 29,300 shares and a transaction value of 733 million [1] Capital Flow Analysis - The medical beauty sector saw a net outflow of 2.1553 million from main funds, while retail funds experienced a net outflow of 3.2717 million [1] - Speculative funds had a net inflow of 5.4269 million [1] Individual Stock Capital Flow - Aimeike had a net outflow of 15.355 million, down 3.21%, with a net inflow of 21.139 million, down 0.44% [2] - *ST Meigu experienced a net outflow of 5.6326 million, down 22.45%, with a net inflow of 4.3275 million, up 17.25% [2] - Huaxi Biological had a net outflow of 13.9915 million, down 8.41%, with a net inflow of 16.4544 million, up 9.89% [2]