Core Viewpoint - Huiyu Pharmaceutical (688553) announced that its wholly-owned subsidiary, Huiyu Haiyue, has initiated a Phase I clinical trial for its self-developed innovative biological drug, HY0001a, aimed at treating advanced solid tumors, with the first patient successfully dosed recently [1] Company Summary - Huiyu Pharmaceutical's subsidiary, Huiyu Haiyue, is responsible for the development of the innovative drug HY0001a [1] - The drug is classified as a Class I biological innovative drug [1] - The clinical trial is focused on advanced solid tumors, indicating a strategic move into a critical area of oncology [1]

Core Viewpoint - Huiyu Pharmaceutical (688553.SH) announced the successful completion of the first dosing of its self-developed innovative drug HY0001a for the treatment of advanced solid tumors in a Phase I clinical trial [1] Group 1 - The drug HY0001a is classified as a Class 1 innovative biological product and is an antibody-drug conjugate [1] - There are currently no approved products targeting the same site both domestically and internationally [1]

金融界消息 截至2025年7月30日收盘，汇宇制药W（688553）报收于22.68元，上涨0.4%，换手率 6.97%，成交量23.95万手，成交金额5.53亿元。 资金流向方面，今日主力资金净流入2521.44万元，占比成交额4.56%。其中，超大单净流入2946.81万 元、占成交额5.33%，大单净流出425.37万元、占成交额0.77%，中单净流出流出530.16万元、占成交额 0.96%，小单净流出1991.28万元、占成交额3.6%。 汇宇制药最新一期业绩显示，截至2025一季报，公司营业总收入2.39亿元、同比减少1.46%，归属净利 润2562.65万元，同比减少155.19%，扣非净利润3441.09万元，同比减少8.27%，流动比率3.409、速动比 率3.189、资产负债率20.27%。 天眼查商业履历信息显示，四川汇宇制药股份有限公司，成立于2010年，位于内江市，是一家以从事医 药制造业为主的企业。企业注册资本42360万人民币，实缴资本36000万人民币。公司法定代表人为丁 兆。 通过天眼查大数据分析，四川汇宇制药股份有限公司共对外投资了13家企业，参与招投标项目693次， 知识 ...

Investment Rating - The report initiates coverage with a "Buy" rating for the company [6][8]. Core Insights - The company has a strong starting point in innovative drug development, with multiple candidates showing First in Class (FIC) potential. The generic drug business is experiencing steady growth while expanding its innovative drug portfolio [3][4]. - In 2024, the company achieved a revenue of 1.094 billion yuan, representing an 18.05% year-on-year increase, and a net profit of 325 million yuan, up 132.78% year-on-year. However, in Q1 2025, the company reported a revenue of 239 million yuan and a net loss of 26 million yuan [3]. - The company has successfully launched 17 new drugs domestically and holds over 400 drug approvals internationally, with more than 190 pending registrations [3][5]. - The company is accelerating its international expansion, particularly in Europe and the US, with foreign sales revenue reaching approximately 166 million yuan in 2024, a growth rate of 97.12% compared to 2023 [5]. Financial Projections - Revenue projections for 2025-2027 are 1.196 billion yuan, 1.446 billion yuan, and 1.742 billion yuan, respectively, with corresponding net profits of 91 million yuan, 201 million yuan, and 301 million yuan. The price-to-earnings (PE) ratios are expected to be 100.40, 45.27, and 30.28 [6][9].

Investment Rating - The report maintains a "Recommended" investment rating for the pharmaceutical industry [1] Core Views - The innovation environment is continuously improving, leading to an optimistic outlook on innovation premiums. In the first half of 2025, global pharmaceutical transactions reached 456, a 32% year-on-year increase, with total upfront payments soaring to $11.8 billion, a 136% increase. The total transaction value hit $130.4 billion, up 58% year-on-year, with Chinese companies contributing nearly 50% of the total value and over 30% of the transaction count [3] - The CXO sector is expected to gradually recover following a supply-side cleansing post-COVID-19, with a significant increase in License-out transactions and total transaction amounts surpassing previous years [4] - The TCE technology is being continuously iterated and updated, with promising clinical data emerging for TCE-based therapies, indicating a strong market potential [5] - The trend towards more effective and scientific weight loss solutions is evident, with GLP-1 drugs generating over $50 billion in global sales, driving capital interest in the sector [6] - There is a growing focus on autoimmune diseases, with significant clinical data supporting new treatments and collaborations in the field [7] Summary by Sections 1. Pharmaceutical Market Tracking - The pharmaceutical industry outperformed the CSI 300 index by 0.21 percentage points in the last week, with a weekly increase of 1.90% [18] - Over the past month, the industry outperformed the CSI 300 index by 6.73 percentage points, with a monthly increase of 10.95% [21][24] 2. Pharmaceutical Sector Trends and Valuation - The pharmaceutical and biotechnology industry index currently has a PE (TTM) of 37.98, above the 5-year historical average of 32.08 [41] 3. Recent Research Achievements - The report highlights various recent research findings, including the positive outlook for the blood products industry and the acceleration of the inhalation drug sector due to policy support [45] 4. Recent Industry Policies and News - The National Healthcare Security Administration has implemented measures to support the high-quality development of innovative drugs, enhancing the support for R&D and clinical applications [46] - Recent news includes significant approvals and collaborations in the pharmaceutical sector, indicating a vibrant market environment [48][49] 5. Key Company Recommendations - The report recommends specific companies based on their potential to benefit from the improving innovation environment and market trends, including CXO firms and those involved in TCE technology [8]

Group 1 - Liu Pharmaceutical Group plans to repurchase shares worth between 100 million and 200 million yuan, with a maximum repurchase price of 25.70 yuan per share [1] - Dongshan Precision intends to invest up to 1 billion USD to build a high-end printed circuit board project to meet the long-term demand for high-end printed circuit boards in emerging scenarios such as AI [1] - Bomaike reported a net profit of 12.39 million yuan for the first half of the year, a year-on-year decline of 80.42% [2] Group 2 - Western Mining achieved a net profit of 1.869 billion yuan in the first half of the year, a year-on-year increase of 15% [2] - Fuliwang expects a net loss of approximately 17 million yuan for the first half of the year, a decrease of 137.12% compared to the same period last year [2] - Digital Certification anticipates a net loss of between 80 million and 96 million yuan for the first half of the year, compared to a loss of 29.25 million yuan in the same period last year [3] Group 3 - Shanghai Construction reported a net profit of 710 million yuan for the first half of the year, a year-on-year decrease of 14.04% [5] - Funneng Co. achieved a net profit of 1.337 billion yuan in the first half of the year, a year-on-year increase of 12.48% [6] - Tengda Construction's total contract amount for the first half of the year decreased by 17.55% year-on-year [7] Group 4 - Fudan Fuhua decided to terminate the public transfer of a 28% stake in a subsidiary due to the lack of a deposit from potential buyers [9] - Fulei Ant's subsidiary has decided to cease operations due to intense competition in the photovoltaic industry and ongoing losses [11] - Dongfang Ocean's subsidiary received a medical device registration certificate for a folic acid testing kit [14] Group 5 - Huayu Pharmaceutical's subsidiary received overseas listing approvals for several products [16] - Feima International received a performance commitment compensation of 437 million yuan from its controlling shareholder [16] - Guangshen Railway signed a cooperation agreement for the Guangzhou East Station renovation project with a total investment of approximately 16.66 billion yuan [16] Group 6 - Anhui Construction won the bid for the S68 Jingde to Jixi Expressway project with an estimated total investment of 5.7 billion yuan [18] - China Communications Construction Company signed new contracts worth 991.054 billion yuan in the first half of the year, a year-on-year increase of 3.14% [19] - Kehui Co. plans to use up to 70 million yuan of idle funds for cash management [22] Group 7 - Biological Shares' subsidiary received a clinical trial approval for a cat mRNA vaccine, the first of its kind in China [23] - Ruipu Biological received a clinical trial approval for a pig mRNA vaccine, which is the first economic animal mRNA vaccine in China [24] - Nanjing New Hundred's major assets were judicially frozen due to liquidity debt crisis faced by its controlling shareholder [27] Group 8 - Changshu Bank plans to merge three village banks and establish branches, pending shareholder approval [28] - Yong'an Pharmaceutical plans to reduce its holdings by up to 2.6323 million shares [29] - Zhujiang Co. received approval from the Shanghai Stock Exchange for a stock issuance to specific targets [31] Group 9 - Sanyangma's subsidiary signed a 120 million yuan procurement contract for sensor products [33] - Jintou City Development plans to purchase a villa property for approximately 7.1854 million yuan [35] - Yuanli Co. intends to acquire 100% of Tongsheng Co. through a combination of cash and stock issuance [36] Group 10 - Xin'an Century's controlling shareholder plans to reduce holdings by up to 2.22% of the company's shares [36] - Fute Technology plans to raise up to 528 million yuan through a private placement for various projects [36] - Helen Piano's actual controller is set to change, with stock resuming trading [37] Group 11 - Weiergao expects a net profit increase of 12.55% to 30.87% for the first half of the year [38] - Saiwei Microelectronics plans to transfer up to 18% of its shares through an agreement [40] - Yongli Co. intends to acquire a 22.75% stake in a subsidiary [42] Group 12 - ST Xiachuang plans to publicly transfer a 20% stake in Guangdong Yuweiji [43] - Dema Technology's shareholders plan to transfer 778.84 million shares through an inquiry [45] - Zhongshi Technology's shareholders plan to reduce holdings by up to 2.86% of the company's shares [46] Group 13 - Wufang Optoelectronics' controlling shareholder plans to reduce holdings by up to 0.93% of the company's shares [48] - Fusenmei's chairman has been detained, temporarily unable to fulfill his duties [49] - Reliable Co.'s shareholders plan to reduce holdings by a total of up to 2.63% of the company's shares [51] Group 14 - Gao Neng Environment plans to repurchase shares worth between 100 million and 150 million yuan [53]

证券代码：688553 证券简称：汇宇制药 公告编号：2025-055 四川汇宇制药股份有限公司 股东名称 黄乾益 股东身份 控股股东、实控人及一致行动人 □是 √否 一、减持主体减持前基本情况 | | 直接持股 5%以上股东 | √是 | □否 | | --- | --- | --- | --- | | | 董事、监事和高级管理人员 | □是 | √否 | | | 其他：不适用 | | | | 持股数量 | 27,219,439股 | | | | 持股比例 | 6.426% | | | | 当前持股股份来源 | IPO 前取得：27,219,439股 | | | 持股 5%以上股东减持股份计划时间届满暨减持股份 结果公告 本公司董事会、全体董事及相关股东保证本公告内容不存在任何虚假记载、 误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律 责任。 重要内容提示： 大股东持股的基本情况 截至本公告披露之日，四川汇宇制药股份有限公司(以下简称"公司")股东 黄乾益持有公司股份数量为 27,219,439 股，占公司总股本的 6.426%；上述股份 来源于公司首次公开发行前取得的股份，且已于 ...

证券代码：688553 证券简称：汇宇制药 公告编号：2025-056 公司唑来膦酸注射液研发成功后已进行了多国注册申报，分别已在中国、英 国、法国、葡萄牙、荷兰、西班牙、意大利、德国等 15 个国家获得上市许可。 截至目前，公司已分别在越南、巴基斯坦等 5 个国家提交注册申请。 （二）注射用赛替派 四川汇宇制药股份有限公司 关于自愿披露公司产品获得境外上市许可的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 四川汇宇制药股份有限公司（以下简称"公司"）子公司 Seacross Pharma (Europe) Ltd.近期收到德国国家药品和保健品安全局和沙特阿拉伯健康产品监管 局分别核准签发的公司产品唑来磷酸注射液、注射用赛替派、丙戊酸钠注射用浓 溶液和注射用盐酸苯达莫司汀的上市许可。现将相关情况公告如下： 二、药品的其他相关情况 （一）唑来膦酸注射液 唑来膦酸注射液主要用于治疗绝经后妇女以及成年男性的骨质疏松症，治疗 绝经后妇女以及成年男性长期糖皮质激素治疗诱发的骨质疏松症，以及成人 Paget's 骨病（变形性骨 ...

汇宇制药公告，公司子公司Seacross Pharma Ltd.近期获得德国国家药品和保健品安全局以及沙特阿拉伯 健康产品监管局的上市许可，涉及唑来磷酸注射液、注射用赛替派、丙戊酸钠注射用浓溶液和注射用盐 酸苯达莫司汀等产品。这些许可有助于公司丰富国际市场产品管线，提升品牌形象，并拓展国际业务的 广度和深度。公司已进行产品上市销售的准备工作，但受市场竞争等因素影响，未来能否产生较大收入 仍具有不确定性。 ...

Market Performance - The recombinant protein concept increased by 2.92%, ranking 7th among concept sectors, with 43 stocks rising, including Chengdu Xian Dao and Mai Wei Bio reaching a 20% limit up [1] - Leading gainers included Shen Zhou Cell, Hai Te Bio, and Ke Xing Pharmaceutical, with increases of 15.40%, 11.93%, and 10.14% respectively [1] - Decliners included ST Wei Ming, *ST Su Wu, and Lizu Group, with decreases of 5.01%, 4.81%, and 0.49% respectively [1] Capital Flow - The recombinant protein sector saw a net inflow of 188 million yuan, with 17 stocks receiving net inflows, and 5 stocks exceeding 30 million yuan in net inflow [1] - Shen Zhou Cell led with a net inflow of 217 million yuan, followed by Chengdu Xian Dao, Mai Wei Bio, and Hui Yu Pharmaceutical with net inflows of 126 million yuan, 96.87 million yuan, and 45.41 million yuan respectively [1] Capital Inflow Ratios - Leading stocks in capital inflow ratios included Shen Zhou Cell, Chengdu Xian Dao, and Cheng Da Bio, with net inflow ratios of 16.25%, 12.33%, and 10.79% respectively [2] - The top stocks in the recombinant protein concept based on capital flow included Shen Zhou Cell, Chengdu Xian Dao, and Mai Wei Bio, with respective daily turnover rates of 3.70%, 12.33%, and 17.80% [2]