股票代码：000538 股票简称：云南白药 公告编号：2025-33 云南白药集团股份有限公司 关于持股 5％以上股东拟非公开发行可交换公司债券及拟 对其持有的部分股票办理担保及信托登记的公告 本公司及董事会全体成员保证信息披露内容的真实、准确、完整，没有 虚假记载、误导性陈述或重大遗漏。 云南白药集团股份有限公司（以下简称"公司"或"云南白药"）于 2025 年 9 月 22 日收到持股 5%以上股东新华都实业集团股份有限公司（以 下简称"新华都"）的书面通知，新华都拟以其持有的部分公司 A 股股票 为标的非公开发行可交换公司债券（以下简称"本次可交换债券"），并 已于近日获得深圳证券交易所出具的《关于新华都实业集团股份有限公司 非公开发行可交换公司债券符合深交所挂牌条件的无异议函》（深证函 〔2025〕881 号，以下简称"《无异议函》"），发行规模不超过 20 亿元 人民币。《无异议函》有效期为自出具之日起 12 个月，新华都将在《无 异议函》有效期内，根据自身资金安排和市场情况，择机发行本次可交换 债券。在满足换股条件下，本次可交换债券的债券持有人有权在换股期内 将其持有的本次可交换债券交换为云南白药 ...

Core Insights - Yunnan Baiyao's smart factory has been recognized as the first certified "Lighthouse Factory" in the global traditional Chinese medicine health product sector, marking a significant achievement in digital manufacturing and intelligent management within the toothpaste industry [1][2] - The certification is considered the "Oscar of manufacturing," highlighting the factory's innovative integration of traditional agriculture with modern technology to create a smart manufacturing system that is transparent, traceable, and perceptible [1] Group 1 - The smart factory has deployed over 7,500 sensors to establish a comprehensive digital management system covering the entire production process [1] - The factory has broken down production processes into 56 minimal functional units, enabling "one-click switching" to address efficiency bottlenecks in multi-category production [1] - Quality control innovations include a "data-driven full-link quality traceability model," which has reduced product release audit times by 55% and decreased active ingredient detection time from 710 minutes to 2 minutes, achieving a 355-fold efficiency improvement [1] Group 2 - The company extends its intelligent practices across the entire industry chain, creating a digital closed-loop from agriculture to industry to market [2] - In the upstream herbal medicine segment, satellite remote sensing and AI yield forecasting are used to establish a digital management system for key quality characteristics of suppliers, enabling rapid responses to large orders and small batch personalized demands [2] - Consumers can scan codes to trace raw material sources, production processes, and testing results, forming a positive feedback loop of market response, R&D optimization, and production iteration [2] - Yunnan Baiyao plans to replicate its "smart manufacturing" model across other product lines, including traditional Chinese medicine health products and wellness foods, promoting technology experiences such as multi-category production switching and full-link quality traceability to support industry upgrades [2]

Core Insights - The "Digital Cloud Medicine" platform, developed by Wenshan Yi Autonomous County and Yunnan Baiyao Group, enhances the red flower industry through comprehensive digitalization from planting to trading, integrating cybersecurity into its core operations [1][2][4] Group 1: Digital Empowerment - The platform has achieved full digital control over the entire process, including seed sourcing, planting, processing, testing, and trading, resulting in a planting area of 28,000 acres and an average income increase of over 20% for 9,900 farmers, equating to approximately 1,600 yuan per acre [2] - The digitalization addresses previous issues of resource fragmentation, inconsistent standards, and poor information flow, transforming valuable resources into a robust industry [1] Group 2: Cybersecurity Integration - Yunnan Baiyao Group has elevated cybersecurity to a strategic priority, establishing a comprehensive information security system that includes technology, regulations, and personnel, ensuring all transactions and data are encrypted and secure [4] - The cybersecurity measures provide a reliable protective framework that safeguards farmers' financial interests and ensures data integrity throughout the digital platform [3][4] Group 3: Replication and Expansion - The "Digital Cloud Medicine" platform is not only successful in Wenshan but is also being replicated in six other counties, creating a sustainable model for digital transformation in the traditional Chinese medicine industry [6] - The integration of cybersecurity into every aspect of the red flower industry chain is seen as a crucial foundation for protecting data and transactions, thereby supporting the livelihoods of numerous farmers [6]

Core Viewpoint - The traditional growth paradigm is being deconstructed and reshaped, necessitating the exploration of new growth paths in the current macroeconomic environment, industry landscape, and market valuation system [3][10]. Group 1: Market Dynamics - The A-share market is experiencing a significant bull market, with all three major indices rising and the ChiNext index reaching a new high [5]. - The average return of actively managed public equity funds has approached 30% since the beginning of the year, significantly outperforming the CSI 300 index [8]. - The improvement in liquidity and the fundamental performance of companies, particularly in the innovative pharmaceutical sector, are driving this bull market [10]. Group 2: Industry Insights - The integration of AI with traditional industries is enhancing efficiency, while sectors like pharmaceuticals and advanced manufacturing are witnessing innovative breakthroughs [3]. - The consumer sector, particularly large consumption, is still perceived to have substantial growth potential despite being relatively low compared to other industries [12]. Group 3: Company Strategies - Yunnan Baiyao emphasizes "guarding and attacking" in its strategy, maintaining market leadership in core products while achieving significant growth in new businesses, such as a 116% increase in the sales of its Qi Xue Kang oral liquid [15]. - Yonghui Supermarket is undergoing a transformation to enhance product and service quality, focusing on employee satisfaction and customer experience through initiatives like the "Craftsman Plan" [15]. - Both companies are adapting to market changes by innovating their product structures and business models, with Yunnan Baiyao leveraging its full industry chain competitiveness [14]. Group 4: Valuation Perspectives - New growth companies require new valuation anchors, with traditional businesses valued by conventional methods and new growth segments assessed based on penetration rates and market space [16]. - A threshold of 30% revenue contribution from new businesses is identified as a critical point for reevaluating valuation approaches [16]. - The ability to continuously innovate and adapt to market demands is seen as a cornerstone of long-term investment value for companies [16].

Group 1 - The 2025 "Belt and Road" Media Cooperation Forum was held in Yunnan, attended by over 200 foreign representatives from 87 countries and international organizations [2] - A research team from 14 countries, including Laos, Cambodia, and Malaysia, conducted investigations into Yunnan Baiyao and the development of traditional Chinese medicine and sports training in Yunnan [2][4] - Yunnan Baiyao's smart toothpaste factory utilizes industrial 4.0 standards, featuring IoT technology and six core information systems, demonstrating high production efficiency with minimal labor [4] Group 2 - Yunnan Baiyao's medicinal plant garden showcases over 1,000 plant species, with more than 600 having medicinal value, highlighting the region's biodiversity and rich history in traditional medicine [6][8] - The company integrates the entire industry chain of traditional Chinese medicine, from cultivation to industrial production and health services, promoting the development of a comprehensive health service system [8] - Traditional Chinese medicine is gaining popularity in countries like Malaysia, with local media expressing interest in the production processes and applications of Chinese herbal products [8]

Group 1: Company Overview - Lepu Medical - Lepu Medical is a leading cardiovascular company in China, with a diverse product matrix. In H1 2025, the company achieved revenue of 3.369 billion yuan, a year-on-year decrease of 0.43%, and a net profit of 691 million yuan, down 0.91% year-on-year [3] - The company is strategically expanding into innovative drugs for cardiovascular and metabolic diseases through its subsidiary, Minwei Biotech, which focuses on obesity and type 2 diabetes treatments. As of August 2025, several products are in various clinical trial phases [3] - Lepu Medical is also actively developing its aesthetic medicine segment, with new products like dermal fillers and hyaluronic acid injections receiving approval, indicating strong growth potential in the non-medical insurance market [3] Group 2: Company Overview - Superwin International Holdings - Superwin International Holdings has over 20 years of experience in elastic fabric, with a stable management team. The company generates 55.4% of its revenue from sports fabrics and is well-positioned to capture more orders due to its mature overseas production capacity [6][7] - The company is expected to see net profits of 590 million, 640 million, and 700 million HKD from 2025 to 2027, benefiting from a rebalancing of supply and demand and moderate raw material prices [5][6] - Superwin has maintained a stable dividend payout ratio of around 50%, with a dividend yield exceeding 9% for the past four years, making it an attractive investment opportunity [8] Group 3: Industry Insights - Biopharmaceuticals - The biopharmaceutical industry is witnessing a shift towards innovative drug development, particularly in cardiovascular and metabolic diseases, driven by companies like Lepu Medical [3] - The market for aesthetic medicine is expanding, with increasing regulatory approvals for new products, indicating a growing consumer demand for non-traditional medical treatments [3] Group 4: Industry Insights - Textile and Apparel - The sportswear segment is outpacing other apparel categories, with rising demand for elastic, breathable, and antibacterial fabrics benefiting suppliers like Superwin International [8] - The company is positioned to leverage its established relationships with major sports brands, which have been in collaboration for over five years, ensuring a steady flow of orders [8]

Overview - The core viewpoint of the article highlights the growing demand for traditional Chinese medicine (TCM) transdermal patches due to their advantages such as no first-pass effect, minimal gastrointestinal damage, low toxicity, prolonged efficacy, and ease of use, particularly among populations that cannot take oral medications, like the elderly and children [1][4][8]. Market Size - The market size of TCM transdermal patches in China is projected to reach 14 billion yuan by 2024, accounting for 65.34% of the overall medicinal patch market [1][8]. Market Policies - The Chinese government has implemented various policies to support the development of the TCM industry, including measures to enhance scientific regulation, promote innovation, and improve healthcare quality from 2023 to 2025 [5][6]. Industry Chain - The upstream of the TCM transdermal patch industry includes suppliers of raw materials such as Chinese medicinal herbs, rubber, and various excipients, while the midstream consists of manufacturers of TCM transdermal patches, and the downstream includes medical institutions, retail pharmacies, and online pharmacies [6][7]. Sales Channels - Medical institutions are the primary sales channel for TCM transdermal patches, accounting for over 60% of sales. By the end of 2024, there will be approximately 1.092 million medical institutions in China, with a 2.0% year-on-year growth [7][8]. Competitive Landscape - The top five companies in the TCM transdermal patch market as of Q1 2025 include Qizheng Group, Yunnan Baiyao, Lingrui Pharmaceutical, Hillman Pharmaceutical, and China Resources Pharmaceutical, with Qizheng Group and Yunnan Baiyao leading the market [10][11]. Company Analysis - Qizheng Tibetan Medicine Co., Ltd. is a leading modern Tibetan medicine company with a revenue of 1.175 billion yuan in the first half of 2025, of which 824 million yuan (70.11%) comes from transdermal patch sales [12]. - Lingrui Pharmaceutical Co., Ltd. reported a total revenue of 2.099 billion yuan in the first half of 2025, with a gross profit of 1.707 billion yuan and a gross margin of 81.33% [13]. Development Trends - The demand for TCM transdermal patches is expected to grow due to the aging population and increasing prevalence of musculoskeletal and cardiovascular diseases. Additionally, the shift in health consciousness and the rise of online sales channels will further expand the market [13].

Core Viewpoint - The traditional Chinese medicine (TCM) sector is experiencing a phase of adjustment, with signs of resilience and potential recovery in profitability, supported by policy backing and market dynamics [3][4]. Group 1: Market Performance - The Shanghai Composite Index experienced a pullback, while the TCM sector continued to adjust, with the TCM ETF (560080) declining by 0.91% for five consecutive days [1]. - The trading volume for the TCM ETF exceeded 120 million yuan, marking a 68% increase compared to the previous day [1]. - The TCM ETF has seen net inflows in 9 out of the last 10 days, accumulating over 150 million yuan, with the latest fund size exceeding 2.4 billion yuan, leading its peers significantly [1]. Group 2: Financial Performance - In the first half of 2025, the TCM sector's total revenue was 172.9 billion yuan, a year-on-year decrease of 4.95%, while the net profit attributable to the parent company was 19.1 billion yuan, down 9.31% [4]. - The operating cash flow improved by 30.77% year-on-year, reaching 16.96 billion yuan [4]. - The gross margin for the TCM sector in H1 2025 was 42.05%, a decrease of 1.01 percentage points year-on-year, while the net profit margin was 11.04%, down 0.56 percentage points [4]. Group 3: Market Dynamics and Trends - Despite short-term demand pressures, the retail pharmacy sector's consolidation is expected to enhance the market concentration of OTC products [7]. - Market shares for leading OTC products have increased, with notable gains for brands like Huazhu Sanjiu and Jiangzhong Pharmaceutical [7]. - The TCM sector is characterized by both new consumer demand and pharmaceutical attributes, suggesting a favorable investment outlook for the TCM ETF (560080) and related funds [7].

Core Viewpoint - The Chinese medicine sector is experiencing a mixed performance, with the leading Chinese medicine ETF (560080) showing resilience despite market fluctuations, attracting significant capital inflows and demonstrating strong growth potential in the context of regulatory changes and industry innovation efforts [1][4][6]. Market Performance - The Chinese medicine ETF (560080) recorded a slight decline but maintained a premium throughout the day, with a trading volume exceeding 71 million yuan. Over the past 10 days, it has seen net inflows on 9 occasions, totaling over 150 million yuan, and its latest scale has surpassed 2.4 billion yuan, leading its peers [1][4]. - Major components of the ETF index mostly experienced pullbacks, with Renhe Pharmaceutical declining over 1%, while Panlong Pharmaceutical rose over 1% [3][5]. Financing and Investment Trends - Leveraged funds are increasingly utilizing the ETF to invest in the high-value Chinese medicine consumer sector, with the latest financing balance approaching 80 million yuan and a financing buy-in amount exceeding 12 million yuan as of September 16, 2025 [4]. - The Chinese medicine industry is viewed as having stable cash flow and high dividends, with companies like Huaren Sanjiu and Jiangzhong Pharmaceutical showing strong performance in their incentive plans, which are expected to drive new growth [7][8]. Regulatory Developments - The National Medical Products Administration has announced new regulations for Chinese medicine production supervision, effective March 1, 2026, emphasizing quality control throughout the entire production process [5]. Innovation and Growth Strategies - Chinese medicine companies are actively pursuing innovation and transformation into chemical and biological pharmaceuticals through self-research, mergers and acquisitions, and strategic partnerships, aiming to create a second growth curve [6]. - The industry is expected to see improved performance in the second half of 2025, driven by reduced cost pressures from declining raw material prices and enhanced operational efficiencies [7][9]. Dividend and Profitability Insights - A significant number of central state-owned enterprises in the Chinese medicine sector are projected to have dividend yields exceeding 3% in 2024, with Jiangzhong Pharmaceutical and Dong'e Ejiao leading in dividend rates [8][9]. - Despite facing growth pressures in the first half of 2025, many companies have managed to achieve positive growth in net profit through quality improvement and efficiency enhancement strategies [9]. Market Sentiment and Future Outlook - The Chinese medicine index is gradually recovering, with institutional holdings remaining light. The sector is expected to attract more capital as it combines attributes of new consumer demand and pharmaceutical needs [10][12].

Core Viewpoint - The recent announcement by the World Economic Forum highlights that 8 out of 12 selected "Lighthouse Factories" are Chinese companies, showcasing China's leading position in the digital and intelligent transformation of manufacturing [1][4]. Group 1: Lighthouse Factories Selection - The new list of "Lighthouse Factories" includes 12 companies globally, with 8 being from China, indicating a significant breakthrough in China's manufacturing sector [1]. - The selected Chinese companies include Tongwei Solar, Eaton Electric, Mettler Toledo, Yunnan Baiyao, Hisense Hitachi, and two subsidiaries of Haier, reflecting the advancements in smart manufacturing [1][2]. Group 2: Technological Advancements - Tongwei Solar's factory utilizes automated production lines and big data analysis to achieve precise control in key processes, reducing energy and material waste [2]. - Eaton Electric's facility in Changzhou has implemented 10 Industry 4.0 solutions, resulting in a 26% increase in production efficiency, a 33% reduction in delivery time, and a 55% increase in capacity since its digital transformation began in 2022 [2]. - Mettler Toledo's Changzhou factory has integrated digital technologies deeply into its operations, achieving a 98.4% on-time delivery rate and a 22% reduction in delivery cycles through 49 Industry 4.0 applications [2]. Group 3: Other Notable Chinese Factories - Yunnan Baiyao has applied digital technology for raw material traceability, process optimization, and quality control [3]. - Hisense Hitachi has improved labor efficiency by 63% and reduced defect rates by 57% through over 70 innovative technology applications in welding and logistics [3]. - Haier's factories have achieved mass customization and rapid delivery through modular design and flexible production techniques [3]. Group 4: International Presence - Lenovo's Monterrey manufacturing base in Mexico and Midea's Racha factory in Thailand are also recognized as "Lighthouse Factories," showcasing China's global manufacturing capabilities [3]. - Lenovo's facility has been upgraded continuously over nearly 20 years, while Midea's factory has implemented 72 digital and AI solutions, reducing order delivery times by 43% and customer complaints by 32% [3]. Group 5: Significance of Lighthouse Factories - The "Lighthouse Factory" initiative, a collaboration between the World Economic Forum and McKinsey, represents the pinnacle of digital manufacturing and serves as a model for global manufacturing excellence [4]. - Since the initiative's inception in 2018, the number of Chinese companies selected has been increasing, reflecting the country's proactive approach in the competitive landscape of intelligent manufacturing [4].