证券代码：002252 证券简称：上海莱士 公告编号：2025-061 上海莱士血液制品股份有限公司 关于回购公司股份比例达到 1%暨回购进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 上海莱士血液制品股份有限公司（"公司"）于 2025 年 1 月 13 日召开了第六 届董事会第七次（临时）会议，审议通过了《关于回购公司股份方案的议案》， 同意公司使用自有或自筹资金以集中竞价交易方式从二级市场回购公司股份，用 于实施员工持股计划或股权激励，拟回购股份的资金总额为不低于人民币 2.5 亿 元（含）且不超过人民币 5 亿元（含），拟回购股份价格不超过人民币 9.55 元/ 股（含），具体回购股份数量以回购股份方案实施完毕或回购实施期限届满时实 际回购情况为准。回购期限自股东大会审议通过本次回购股份方案之日起 12 个 月内，如果触及回购股份方案提及的相关条件时，回购期限提前届满。公司于 2025 年 2 月 14 日召开 2025 年第一次临时股东大会审议通过了上述股份回购方 案。具体内容详见公司分别于 2025 年 1 月 14 日、2025 年 2 ...

Core Insights - The A-share market continues to rise, leading to a prosperous season for brokerage firms, with 42 listed brokerages achieving a total operating income of 251.87 billion yuan and a net profit of 104.02 billion yuan in the first half of the year, representing year-on-year growth of 11.37% and 65.08% respectively [1] - The significant increase in brokerage performance is largely attributed to proprietary trading, which generated a total income of 112.35 billion yuan, a year-on-year increase of over 50%, accounting for more than 40% of total income [1][2] - Among the brokerages, CITIC Securities stands out as the only firm with proprietary income exceeding 10 billion yuan, reaching 19.05 billion yuan, contributing approximately 57% to its total revenue [2] Brokerage Performance - In the first half of the year, 25 out of 42 listed brokerages reported proprietary income exceeding 1 billion yuan, accounting for nearly 60% of the total [2] - Notable performers include Changjiang Securities, which saw a staggering year-on-year increase of 668.35% in proprietary income, and Guolian Minsheng and Huaxi Securities with increases of 458.78% and 245.07% respectively [2] Stock Holdings - As of the end of June, the top three stocks held by brokerages were Jiangsu Bank, Yong'an Futures, and CITIC Construction Investment, with holdings of 923 million shares, 43.9 million shares, and 38.3 million shares respectively, translating to market values of 11.03 billion yuan, 6.51 billion yuan, and 9.21 billion yuan [4] - Brokerages have shown a preference for sectors such as non-bank financials, electronics, and biomedicine in their proprietary trading [1] Changes in Holdings - In the second quarter, significant increases in holdings were observed in stocks like Sichuan Chengyu, Hongchuang Holdings, and Yuntianhua, with increases of 9.89 million shares, 5.76 million shares, and 5 million shares respectively [6] - Conversely, stocks such as Huangshi Group, Shanghai Mechanical, and Northeast Securities experienced substantial reductions in holdings, with the largest decrease being 14 million shares for Huangshi Group [8][11] Regulatory Impact - Some stocks faced significant reductions in holdings due to regulatory penalties, with brokerages exiting positions in companies like Huangshi Group, which was under investigation for information disclosure violations [10][11]

Core Viewpoint - The blood products industry is experiencing significant performance differentiation among listed companies due to fluctuating terminal medical demand, ongoing centralized procurement policies, and intensified competition for plasma station resources [1][2]. Revenue Performance - The blood products industry has shown a clear tiered revenue structure, with leading companies benefiting from resource barriers while smaller firms struggle with revenue growth [2][3]. - Shanghai Raist achieved a revenue of 3.952 billion yuan, with a year-on-year plasma collection increase of nearly 12% [2]. - Tian Tan Bio reported a revenue of 3.110 billion yuan, a year-on-year increase of 9.47%, supported by its stable plasma collection capabilities [2]. - Hualan Bio generated a revenue of 1.798 billion yuan, up 8.8% year-on-year, with its blood products segment contributing 1.737 billion yuan, a 7.57% increase [2]. - The top three companies accounted for 74.64% of the total revenue of the eight listed companies in the industry [2]. Profitability Analysis - There is a significant disparity in net profit performance, with only two companies reporting positive year-on-year growth in net profit [4][5]. - Shanghai Raist led with a net profit of 1.03 billion yuan, while Hualan Bio saw a notable increase of 17.19% in net profit to 516 million yuan, driven by improved gross margins [4]. - Tian Tan Bio's net profit decreased by 12.88% to 633 million yuan, impacted by declining product sales prices and reduced interest income [4]. - The profitability of smaller companies is under pressure, with Baiya Bio reporting a net profit of 225 million yuan and a cash dividend plan reflecting shareholder returns [5]. - Bai Lin Bio's net profit fell by 27.89% to 236 million yuan due to capacity expansion efforts, while Wei Guang Bio's net profit slightly decreased by 2.02% to 108 million yuan [5][6]. Industry Challenges - The industry faces challenges such as weak terminal demand, ongoing centralized procurement pressures, and financial and R&D constraints [6]. - The demand for conventional products like human albumin has decreased due to adjustments in treatment rhythms at medical institutions [6]. - Centralized procurement policies continue to exert pressure on pricing, affecting revenue from related business lines [6]. - Companies are experiencing tight funding issues as they invest in expanding plasma stations and advancing new product development [6].

Core Viewpoint - Shanghai Laishi is actively enhancing its market position through strategic share buybacks, continuous growth in plasma collection, and acquisitions, aiming to become a world-class biopharmaceutical company. Group 1: Share Buyback and Investor Confidence - As of August 22, 2025, Shanghai Laishi's controlling shareholder, Haiyingkang, has increased its stake by 2,644.08 shares, representing 0.40% of the total share capital, with an investment of 181 million yuan [1] - This buyback plan reflects Haiyingkang's confidence in Shanghai Laishi's future development and long-term investment value, which is expected to bolster investor confidence [1] Group 2: Plasma Collection and Industry Position - Shanghai Laishi leads the domestic blood products industry, with plasma collection exceeding 1,600 tons in 2024, supported by six production bases and 55 plasma collection stations across 11 provinces [2] - In the first half of 2025, plasma collection increased by over 12% year-on-year, with significant growth in the issuance of various blood products, including a 9% increase in domestic albumin and an 18% increase in human coagulation factor VIII [2] Group 3: Strategic Acquisitions - The acquisition of Nanyue Biological, completed in June 2025, marks a significant step in Shanghai Laishi's "expansion" strategy, enhancing its production capacity and market presence [3] - Nanyue Biological, the only blood product manufacturer in Hunan with GMP certification, adds nine plasma collection stations and a potential increase in plasma collection volume to Shanghai Laishi's operations [3] Group 4: Research and Development Focus - Shanghai Laishi emphasizes R&D as a core development strategy, achieving breakthroughs in key therapeutic areas, including the first virus-inactivated human coagulation factor product [4] - The company is advancing multiple R&D pipelines, with a focus on high-value products and expanding existing product indications, supported by a research investment of 101 million yuan in the first half of 2025 [5] Group 5: Future Growth Strategy - Shanghai Laishi aims to balance its "expansion" and "de-expansion" strategies, focusing on becoming a world-class biopharmaceutical enterprise while contributing to the vision of "health for all" in China [5]

Core Insights - Shanghai Laishi reported a revenue of 3.952 billion yuan and a net profit of 1.03 billion yuan for the first half of the year, driven by policy guidance and clinical demand in the coagulation factor product market [1][2] Group 1: Financial Performance - The company experienced a 29.70% year-on-year increase in sales volume of human fibrinogen, maintaining the top market share in the industry [1] - Sales volume of human coagulation factor VIII grew by 34.40%, positioning it as a new growth engine for the company [1] Group 2: Market Strategy and Operations - The company is actively expanding plasma resources and accelerating the implementation of its defatting strategy to adapt to market changes [1] - By mid-2025, the plasma collection volume is expected to increase by nearly 12% year-on-year, ensuring stable expansion of plasma supply [1] Group 3: Mergers and Acquisitions - The successful acquisition of Nanyue Biological in June 2025 enhanced the company's overall scale and plasma station coverage [1] Group 4: Research and Development - The company is focused on optimizing product structure and accelerating the development of high-value-added products, particularly in the coagulation and immunoglobulin sectors [2] - The innovative research result "SR604" for hemophilia treatment has entered Phase IIb clinical trials, with a recent application for clinical trials for a specific indication being accepted by the National Medical Products Administration [2] Group 5: Future Outlook - The company aims to advance plasma resource construction, innovative drug development, and marketing model upgrades to achieve high-quality growth [2] - The strategic focus remains on the dual approach of "expanding plasma" and "defatting" to become a world-class biopharmaceutical enterprise [2]

这里是《21健讯Daily》，欢迎与21世纪经济报道新健康团队共同关注医药健康行业最新事件！政策动 向 广州"穗新保"新增60种创新药械和6家医院 8月28日，广州市医保局举办"穗新保"新增试点医院签约活动，6家试点商保公司与6家新增试点医疗机 构签署合作协议。广州快速推进"穗新保"扩容提质，全新升级"穗新保"保障范围，新增"60+6"的产品目 录及试点医院。 21点评："穗新保"作为全国首个同步涵盖"港澳药械通"及本地创新药械的商业保险，重点保障省、市创 新药械目录和"港澳药械通"内尚未纳入医保支付范围的产品费用，此前已纳入44种。 山东加强省级仿制药质量和疗效一致性评价补助资金管理 近日，山东省药监局、山东省财政厅联合印发《山东省省级仿制药质量和疗效一致性评价补助资金管理 办法和实施细则》，持续支持和激励山东省药品上市许可持有人开展仿制药一致性评价工作。《细则》 自2025年9月1日起施行，有效期至2027年8月31日。 8月29日，国家药监局官网显示，恒瑞医药（600276）申报的1类新药泽美妥司他片(商品名：艾瑞璟)获 批上市，为国内获批的首个国产EZH2抑制剂，适用于既往接受过至少1线系统性治疗的复 ...

Core Viewpoint - Shanghai Laishi's half-year report for 2025 indicates a decline in revenue and net profit, highlighting challenges in the blood products industry while emphasizing ongoing innovation and strategic growth initiatives. Financial Performance - In the first half of 2025, the company achieved operating revenue of 3.952 billion yuan, a year-on-year decrease of 7.06% [1] - The net profit attributable to shareholders was 1.03 billion yuan, with a non-recurring net profit of 1.04 billion yuan, both showing a decline of 7.84% year-on-year [1] Business Overview - Shanghai Laishi is a leading manufacturer of blood products in China, focusing on human serum albumin, immunoglobulins, and coagulation factor products [1] - The company has exclusive distribution rights for certain blood products in mainland China through its subsidiary Tonglu Medicine [1] Market Dynamics - The demand for blood products remains stable due to their clinical irreplaceability and strong correlation with demographic changes [2] - The market for coagulation factor products is growing rapidly, driven by policy guidance and clinical demand, although challenges from increased supply and regulatory impacts are noted [2] Innovation and R&D - The company is committed to enhancing its product structure and accelerating the development of high-value products, particularly in the fields of coagulation and immunoglobulin [2] - Shanghai Laishi's innovative research in hemophilia treatment, specifically the "SR604" injection, has entered phase IIb clinical trials, with an application for a new indication recently accepted by the National Medical Products Administration [2] Strategic Initiatives - The company has established a multi-dimensional R&D system focusing on independent innovation, patent introduction, and technology collaboration [3] - Recent acquisitions, including the successful purchase of Nanyue Biotechnology, have expanded the company's scale and coverage in plasma stations [3] - With Haier Group as the controlling shareholder, the company is enhancing its global development strategy through resource integration and market expansion [3]

财务报表中对有大幅变动的财务项目的原因说明如下： 应收款项变动幅度为43.4%,原因:销售信用政策调整。 据证券之星公开数据整理，近期上海莱士（002252）发布2025年中报。根据财报显示，上海莱士净利润 同比下降17%。截至本报告期末，公司营业总收入39.52亿元，同比下降7.06%，归母净利润10.3亿元， 同比下降17.0%。按单季度数据看，第二季度营业总收入19.46亿元，同比下降11.37%，第二季度归母净 利润4.64亿元，同比下降4.17%。 本次财报公布的各项数据指标表现一般。其中，毛利率37.73%，同比减7.7%，净利率26.05%，同比减 10.73%，销售费用、管理费用、财务费用总计2.92亿元，三费占营收比7.4%，同比减20.3%，每股净资 产4.88元，同比增5.53%，每股经营性现金流0.11元，同比增1656.46%，每股收益0.15元，同比减17.11% | 项目 | 2024年中报 | 2025年中报 | 同比增幅 | | --- | --- | --- | --- | | 营业总收入(元) | 42.52 乙 | 39.52亿 | -7.06% | | 归母净利润(元 ...

格隆汇8月29日丨上海莱士(002252.SZ)公布2025年半年度报告，上半年公司实现营业收入39.52亿元，同 比下降7.06%；归属于上市公司股东的净利润10.30亿元，同比下降17.00%；归属于上市公司股东的扣除 非经常性损益的净利润10.40亿元，同比下降7.84%；基本每股收益0.155元。 ...

Core Insights - Shanghai Laishi reported significant improvements in operating cash flow and a strong cash reserve of 3.489 billion yuan as of June 2025, indicating robust financial health and resilience [1] - The company achieved a revenue of 3.952 billion yuan and a net profit attributable to shareholders of 1.03 billion yuan in the first half of 2025, reflecting a solid performance in the blood products sector [1] - The company has expanded its production capabilities with six blood product manufacturing bases and 55 plasma collection stations across 11 provinces, leading to a nearly 12% increase in plasma collection volume year-on-year [1] Industry Developments - The market for coagulation factor products is rapidly growing, driven by policy guidance and clinical demand, with sales of human fibrinogen increasing by 29.70% and human coagulation factor VIII by 34.40% in the first half of 2025 [2] - Shanghai Laishi's innovative research in the field of hemophilia treatment has progressed, with the "SR604" injection entering phase IIb clinical trials, focusing on prevention treatment for bleeding episodes in patients with von Willebrand disease [2]