海思科医药集团股份有限公司 关于持股 5%以上股东部分股份质押的公告 本公司及董事会全体成员保证信息披露内容的真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 海思科医药集团股份有限公司（以下简称"公司"）于近日接到 公司股东范秀莲女士的通知，获悉其所持有本公司的部分股份被质押， 具体事项如下： 证券代码：002653 证券简称：海思科 公告编号：2025-132 本次质押股份未负担重大资产重组等业绩补偿义务。 二、股东股份累计质押的情况 截至公告披露日，上述股东及其一致行动人所持质押股份情况如 下： | | | | | | | | 已质押股份情况 | | 未质押股份情况 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 股东 | 持股 | 持股 | 本次质押前 | 本次质押后 | 占其所 | 占公司 | | | | | | | 数量 | | 质押股份数 | 质押股份数 | 持股份 | 总股本 | 已质押股 | 占已 | 未质押股 | 占未 | | 名称 | （万股） | 比例 | 量（万股） | 量（万 ...

每经头条（nbdtoutiao）——海南封关政策红利全解析：零关税、低个税、投资准入放宽、跨境资金自 由、创业扶持…… 2025年1至6月份，海思科的营业收入构成为：医药行业占比99.14%，其他业务占比0.86%。 截至发稿，海思科市值为577亿元。 每经AI快讯，海思科（SZ 002653，收盘价：51.5元）12月18日晚间发布公告称，海思科医药集团股份 有限公司于2025年12月18日收到政府补助1.2亿元，占2024年度经审计归属于上市公司股东净利润的 30.34%。 （记者 曾健辉） ...

这里是《21健讯Daily》，欢迎与21世纪经济报道新健康团队共同关注医药健康行业最新事件！ 政策动向 江西出台13条措施全面促进药品零售连锁产业高质量发展 近日，江西省药监局、省医保局联合印发《优化审批流程促进药品零售连锁产业高质量发展若干政策措 施》，以支持企业整合、简化审批流程、鼓励委托储存配送等13条政策措施，力促药品零售连锁产业高 质量发展。 《若干政策措施》提出，支持药品零售连锁企业利用参股、重组、兼并、合作等方式进行整合；鼓励药 品零售企业创新经营模式，支持提供药事服务、健康监测、康复咨询、慢病管理、代煎配送等延伸服 务，并积极引导药品零售连锁企业向偏远地区、城乡接合部、农村地区等药店数量较少、居民购药不方 便的区域布局发展。 12月16日，海思科(002653.SZ)公告称，子公司上海海思盛诺医药科技有限公司近日收到国家药品监督 管理局下发的4个创新药《药物临床试验批准通知书》。这些药品包括HSK45019片、HSK50042片、注 射用HSK55718和HSK36357胶囊，分别用于治疗炎症性肠病、呼吸系统疾病、急性疼痛和肌营养不良 症。这些药品均属于化学药品1类，具有独立知识产权。海思科提 ...

12月16日，海思科（002653）公告称，子公司上海海思盛诺医药科技有限公司近日收到国家药品监督管 理局下发的《药物临床试验批准通知书》，同意开展HSK45019片、HSK50042片、注射用HSK55718、 HSK36357胶囊4款化学药品1类创新药的临床试验。 点评：短期内多款1类新药获批临床，体现海思科研发管线的广度。不过，创新药研发周期长、环节 多、风险高，容易受到一些不确定性因素的影响，投资者需持续观察临床进展。 NO.3阳光诺和：与北京大学医学部共建联合实验室 丨 2025年12月17日星期三丨 NO.1全球首个治疗药物成瘾的侵入式脑机接口产品在中国获批 12月15日，中国国家药品监督管理局签发了景昱医疗科技(苏州)股份有限公司侵入式脑机接口治疗药物 成瘾的三类产品注册证。这是全球首个获批用于治疗成瘾类精神疾病的侵入式脑机接口产品。该系统对 伏隔核和内囊前肢进行刺激，用于难治性的中重度阿片类药物成瘾患者的防复发辅助治疗。植入式脑深 部神经刺激系统填补了物理性干预阿片类药物成瘾治疗的技术空白，为阿片类药物成瘾患者的治疗提供 了更多选择。 点评：该产品获批具有里程碑意义，显示我国脑机接口产品在精神 ...

NO.1 全球首个治疗药物成瘾的侵入式脑机接口产品在中国获批 12月15日，中国国家药品监督管理局签发了景昱医疗科技（苏州）股份有限公司侵入式脑机接口治疗药 物成瘾的三类产品注册证。这是全球首个获批用于治疗成瘾类精神疾病的侵入式脑机接口产品。该系统 对伏隔核和内囊前肢进行刺激，用于难治性的中重度阿片类药物成瘾患者的防复发辅助治疗。植入式脑 深部神经刺激系统填补了物理性干预阿片类药物成瘾治疗的技术空白，为阿片类药物成瘾患者的治疗提 供了更多选择。 点评：该产品获批具有里程碑意义，显示我国脑机接口产品在精神疾病治疗领域的应用走在全球前列。 但侵入式方案在安全性上仍需长期验证，商业表现亦有待观察。 NO.2 海思科子公司四款新药获批临床 12月16日，海思科公告称，子公司上海海思盛诺医药科技有限公司近日收到国家药品监督管理局下发的 《药物临床试验批准通知书》，同意开展HSK45019片、HSK50042片、注射用HSK55718、HSK36357 胶囊4款化学药品1类创新药的临床试验。 点评：短期内多款1类新药获批临床，体现海思科研发管线的广度。不过，创新药研发周期长、环节 多、风险高，容易受到一些不确定性因素的影 ...

证券日报网讯 12月16日晚间，海思科发布公告称，子公司上海海思盛诺医药科技有限公司于近日收到 国家药品监督管理局下发的《药物临床试验批准通知书》，经审查，2025年10月受理的HSK45019片、 HSK50042片、注射用HSK55718、HSK36357胶囊临床试验申请符合药品注册的有关要求，同意开展临 床试验。 （文章来源：证券日报） ...

Group 1 - Action Education plans to repurchase shares worth between 20 million to 25 million yuan at a price not exceeding 45 yuan per share for employee stock ownership plans or equity incentives [1] - Fulin Technology's shareholders plan to reduce their holdings by up to 2% of the company's total shares, amounting to a maximum of 24.44 million shares starting from December 22, 2025 [2] - Huashu shares' shareholders intend to reduce their holdings by up to 1% of the company's total shares, which is a maximum of 35.94 million shares [3] Group 2 - Silan Microelectronics has obtained a filing certificate for its 12-inch high-end analog integrated circuit chip manufacturing production line project, with an investment of 10 billion yuan and a monthly production capacity of 20,000 wafers [4] - Aerospace Information confirms that its main business does not involve commercial aerospace and that its operations are normal without significant changes [5] - Qinglong Pipe Industry signed a supply contract worth 294 million yuan for PCCP and pressure steel pipes, accounting for 10.43% of its 2024 revenue [6] Group 3 - Huaxin Precision plans to invest up to 1 billion yuan of idle funds in low-risk financial products [7] - Hainan Rubber received insurance compensation totaling approximately 26.65 million yuan for rubber income and tree insurance [8] - Lianmei Holdings announced the suspension of its subsidiary Fulin Thermal Power due to economic slowdown and reduced customer demand [9] Group 4 - Ruifeng Bank has been approved to issue up to 2.5 billion yuan in secondary capital bonds to enhance its capital and risk resistance [11] - China Pacific Insurance reported a 9.4% year-on-year increase in premium income for its life insurance subsidiary, totaling 250.32 billion yuan [12] - Sunshine Nuohuo signed an agreement with Peking University to establish a joint laboratory for innovative drug development [13] Group 5 - Century Huatong completed the cancellation of 56.12 million repurchased shares, reducing its total share capital from 7.428 billion to 7.372 billion shares [14] - Yaxin Security received a government subsidy of 3 million yuan [15] - Haili Biology's subsidiary received registration certification for a bone repair material in Indonesia [16] Group 6 - Yian Technology's subsidiary secured a major project for magnesium alloy components worth 430 million yuan, expected to start production by the end of March 2026 [17] - Jiangte Electric plans to contest the proposed cancellation of its lithium-containing mining rights [18] - COFCO Technology announced the resignation of its deputy general manager due to work changes [19] Group 7 - Fangsheng Pharmaceutical passed the GMP compliance inspection for its raw material production lines [21] - Bohai Ferry announced the resignation of two deputy general managers for personal and age-related reasons [22] - ST Fuhua appointed a new general manager [23] Group 8 - Huazhong CNC received project funding of 17.7 million yuan, accounting for 31.97% of its audited net profit for 2024 [24] - Oppein Home used 15 million yuan of idle funds to purchase a large time deposit with a 0.9% annual yield [25] - China General Nuclear Power's Ningde Unit 6 has begun full construction, utilizing Hualong One technology with a capacity of 1210 MW [26] Group 9 - Jiayuan Technology's chairman has had the investigation order lifted, and the company is operating normally [27] - Fulaixin Materials' application for a specific stock issuance has been approved by the Shanghai Stock Exchange [28] - Shuhua Sports plans to invest up to 500 million yuan in a health industry park project [29] Group 10 - Rhine Biology's stock will continue to be suspended due to ongoing control change and asset acquisition plans [30] - Haishi Science received approval for clinical trials for four innovative drugs targeting various diseases [31] - Hangcai Co. plans to repurchase shares worth between 50 million to 100 million yuan at a price not exceeding 80 yuan per share [32] Group 11 - Yinxin Technology received a cash dividend of 18 million yuan from its subsidiary [33] - Tianfulong plans to increase its wholly-owned subsidiary's capital by 580 million yuan [34] - Poly United's subsidiary won a bid for a stripping project worth 1.528 billion yuan [35] Group 12 - Minglida's deputy general manager resigned due to health reasons [36] - ST Guohua appointed a new deputy general manager [37] - China Xidian's subsidiaries won contracts totaling 1.005 billion yuan for Southern Power Grid projects [38]

格隆汇12月16日丨海思科(002653.SZ)公布，子公司上海海思盛诺医药科技有限公司于近日收到国家药 品监督管理局下发的《药物临床试验批准通知书》，根据《中华人民共和国药品管理法》及有关规定， 经审查，2025年10月受理的HSK45019片、HSK50042片、注射用HSK55718、HSK36357胶囊临床试验 申请符合药品注册的有关要求，同意开展临床试验。根据国家药品监督管理局关于发布《化学药品注册 分类及申报资料要求》的通告（2020年第44号）中化学药品注册分类的规定，以上四个药品均属于化学 药品1类。 | 药品名称 | 剂型 | 申请事项 | 适应症 | 受理号 | | --- | --- | --- | --- | --- | | HSK45019 | 片剂 | 境内生产药品 | 炎症性肠病 | CXHL2501072 | | | | | | CXHL2501073 | | HSK50042 | | | 呼吸系统疾病 | CXHL2501080 | | | | | | CXHL2501081 | | HSK55718 | 注射剂 | 注册临床试验 | 急性疼痛 | CXHL2501077 | ...

每经AI快讯，12月16日，海思科(002653.SZ)公告称，子公司上海海思盛诺医药科技有限公司近日收到 国家药品监督管理局下发的4个创新药《药物临床试验批准通知书》。这些药品包括HSK45019片、 HSK50042片、注射用HSK55718和HSK36357胶囊，分别用于治疗炎症性肠病、呼吸系统疾病、急性疼 痛和肌营养不良症。这些药品均属于化学药品1类，具有独立知识产权。海思科提醒，创新药研发存在 周期长、环节多、风险高等不确定性因素，投资者需谨慎决策，注意投资风险。 （文章来源：每日经济新闻） ...

智通财经APP讯，海思科(002653.SZ)公告，公司子公司上海海思盛诺医药科技有限公司于近日收到国家 药品监督管理局下发的《药物临床试验批准通知书》，HSK45019片、HSK50042片、注射用 HSK55718、HSK36357胶囊获准开展临床试验，相对应适应症分别为：炎症性肠病、呼吸系统疾病、急 性疼痛、肌营养不良症。 ...